1,235
Views
41
CrossRef citations to date
0
Altmetric
INTRODUCTION

How Can We Assess Outcomes of Clinical Trials: The MCID Approach

Pages 191-194 | Published online: 02 Jul 2009

REFERENCES

  • Kaplan R M, Ries A L. Quality of life: Concept and definition. J COPD 2007, (In press)
  • Jones P W. Activity limitation and quality of life in COPD. J COPD 2007, (In press)
  • Berry M J. The relationship between exercise tolerance and other outcomes in COPD. J COPD 2007, (In press)
  • Cohen J. Statistical power analysis for the behavioural sciences. Academic Press, LondonEngland 1969
  • Jaeschke R, Singer J, Guyatt G H. Measurement of health status. Ascertaining the minimal clinically important difference. Control Clin Trials 1989; 10: 407–415
  • Man-Son-Hing M, Laupacis A, O'Rourke K, Molnar F J, Mahon J, Chan K B, Wells G. Determination of the clinical importance of study results. J Gen Intern Med 2002; 17: 469–476
  • Sloan J A. Assessing the minimally clinically significant difference: Scientific considerations, challenges, and solutions. J COPD 2005; 2: 57–62
  • Guyatt G H, Osoba D, Wu A W, Wyrwich K W, Norman G R. Methods to explain the clinical significance of health status measures. Mayo Clin Proc 2002; 77: 371–383
  • Leidy N K, Wyrwich K W. Bridging the gap: Using triangulation methodology to estimate minimal clinically important differences (MCIDs). J COPD 2005; 2: 157–165
  • Make B, Casaburi R, Leidy N K. Interpreting results from clinical trials: Understanding minimal clinically important differences in COPD outcomes. J COPD 2005; 2: 1–5
  • Jones P W. St. George's respiratory questionnaire: MCID. J COPD 2005; 2: 75–79
  • Norman G R, Sloan J A, Wyrwich K W. Interpretation of changes in health-related quality of life: The remarkable universality of half a standard deviation. Med Care 2003; 41: 582–592
  • Wells G, Beaton D, Shea B, Boers M, Simon L, Strand V, Brooks P, Tugwell P. Minimal clinically important differences: Review of methods. J Rheumatol 2001; 28: 406–412
  • Wyrwich K W, Tierney W M, Wolinsky F D. Further evidence supporting a sem-based criterion for identifying meaningful intra-individual changes in health-related quality of life. J Clin Epidemiol 1999; 52: 861–873
  • Hays R D, Farivar S S, Liu H. Approaches and recommendations for estimating minimally important differences for health-related quality of life measures. J COPD 2005; 2: 63–67
  • Redelmeier D A, Bayoumi A M, Goldstein R S, Guyatt G H. Interpreting small differences in functional status: The six minute walk test in chronic lung disease patients. Am J Respir Crit Care Med 1997; 155: 1278–1282
  • Redelmeier D A, Guyatt G H, Goldstein R S. Assessing the minimal important difference in symptoms: A comparison of two techniques. J Clin Epidemiol 1996; 49: 1215–1219
  • Wyrwich K W, Fihn S D, Tierney W M, Kroenke K, Babu A N, Wolinsky F D. Clinically important changes in health-related quality of life for patients with chronic obstructive pulmonary disease: An expert consensus panel report. J Gen Intern Med 2003; 18: 196–202

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.