Pannexin1 Single Nucleotide Polymorphism and Platelet Reactivity in a Cohort of Cardiovascular Patients

References

• Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, et al. 2006. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet. 38:644–651.
   PubMed Web of Science ®Google Scholar
• Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, et al. 2010. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 467:863–867.
   PubMed Web of Science ®Google Scholar
• Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG. 2006. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science. 314:1792–1795.
   PubMed Web of Science ®Google Scholar
• Chen Y, Yao Y, Sumi Y, Li A, To UK, Elkhal A, Inoue Y, Woehrle T, Zhang Q, Hauser C, Junger WG. 2010. Purinergic signaling: a fundamental mechanism in neutrophil activation. Sci Signal. 3:ra45.
   PubMed Web of Science ®Google Scholar
• Creager MA. 1998. Results of the CAPRIE trial: efficacy and safety of clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events. Vasc Med. 3:257–260.
   PubMedGoogle Scholar
• Daneshjou R, Gamazon ER, Burkley B, Cavallari LH, Johnson JA, Klein TE, Limdi N, Hillenmeyer S, Percha B, Karczewski KJ, et al. 2014. Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans. Blood. 124:2298–2305.
   PubMed Web of Science ®Google Scholar
• Fontana P, Berdague P, Castelli C, Nolli S, Barazer I, Fabbro-Peray P, Schved JF, Bounameaux H, Mach F, de Moerloose P, Reny JL. 2010. Clinical predictors of dual aspirin and clopidogrel poor responsiveness in stable cardiovascular patients from the ADRIE study. J Thromb Haemost. 8:2614–2623.
   PubMed Web of Science ®Google Scholar
• Fontana P, James R, Barazer I, Berdague P, Schved JF, Rebsamen M, Vuilleumier N, Reny JL. 2011. Relationship between paraoxonase-1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study. J Thromb Haemost. 9:1664–1666.
   PubMed Web of Science ®Google Scholar
• Fontana P, Nolli S, Reber G, de Moerloose P. 2006. Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers. J Thromb Haemost. 4:813–819.
   PubMed Web of Science ®Google Scholar
• Ioannidis JP, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG. 2001. Replication validity of genetic association studies. Nat Genet. 29:306–309.
   PubMed Web of Science ®Google Scholar
• Lohman AW, Billaud M, Isakson BE. 2012. Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovasc Res. 95:269–280.
   PubMed Web of Science ®Google Scholar
• Meens MJ, Kwak BR, Duffy HS. 2015. Role of connexins and pannexins in cardiovascular physiology. Cell Mol Life Sci. 72:2779–2792.
   PubMed Web of Science ®Google Scholar
• Molica F, Morel S, Meens MJ, Denis JF, Bradfield PF, Penuela S, Zufferey A, Monyer H, Imhof BA, Chanson M, et al. 2015. Functional role of a polymorphism in the Pannexin1 gene in collagen-induced platelet aggregation. Thromb Haemost. 114:325–336.
   PubMed Web of Science ®Google Scholar
• Moshfegh K, Redondo M, Julmy F, Wuillemin WA, Gebauer MU, Haeberli A, Meyer BJ. 2000. Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy. J Am Coll Cardiol. 36:699–705.
   PubMed Web of Science ®Google Scholar
• Pelegrin P, Barroso-Gutierrez C, Surprenant A. 2008. P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J Immunol. 180:7147–7157.
   PubMed Web of Science ®Google Scholar
• Pelegrin P, Surprenant A. 2006. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J. 25:5071–5082.
   PubMed Web of Science ®Google Scholar
• Penuela S, Harland L, Simek J, Laird DW. 2014. Pannexin channels and their links to human disease. Biochem J. 461:371–381.
   PubMed Web of Science ®Google Scholar
• Reny JL, Berdague P, Poncet A, Barazer I, Nolli S, Fabbro-Peray P, Schved JF, Bounameaux H, Mach F, de Moerloose P, et al. 2012. Antiplatelet drug response status does not predict recurrent ischemic events in stable cardiovascular patients: results of the Antiplatelet Drug Resistances and Ischemic Events study. Circulation. 125:3201–3210.
   PubMed Web of Science ®Google Scholar
• Sosinsky GE, Boassa D, Dermietzel R, Duffy HS, Laird DW, MacVicar B, Naus CC, Penuela S, Scemes E, Spray DC, et al. 2011. Pannexin channels are not gap junction hemichannels. Channels (Austin). 5:193–197.
   PubMed Web of Science ®Google Scholar
• Taylor KA, Wright JR, Vial C, Evans RJ, Mahaut-Smith MP. 2014. Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost. 12:987–998.
   PubMed Web of Science ®Google Scholar
• Thompson RJ, Jackson MF, Olah ME, Rungta RL, Hines DJ, Beazely MA, MacDonald JF, MacVicar BA. 2008. Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science. 322:1555–1559.
   PubMed Web of Science ®Google Scholar
• Weilinger NL, Tang PL, Thompson RJ. 2012. Anoxia-induced NMDA receptor activation opens pannexin channels via Src family kinases. J Neurosci. 32:12579–12588.
   PubMed Web of Science ®Google Scholar
• Zufferey A, Reny JL, Combescure C, de Moerloose P, Sanchez JC, Fontana P. 2011. Platelet reactivity is a stable and global phenomenon in aspirin-treated cardiovascular patients. Thromb Haemost. 106:466–474.
   PubMed Web of Science ®Google Scholar