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Original Articles

Generating Nano-Aerosols from TiO2 (5 nm) Nanoparticles Showing Different Agglomeration States. Application to Toxicological Studies

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Pages 86-96 | Published online: 19 Dec 2012

REFERENCES

  • Schrand , A. L. , Liming , D. , Schlager , J. J. and Hussain , S. M. 2012 . Toxicity testing of nanomaterials . Adv. Exp. Med. Biol. , 745 : 58 – 75 .
  • Balbus , J. M. , Maynard , A. D. and Colvin , V. L. 2007 . Meeting report: Hazard assessment for nanoparticles—Report from an interdisciplinary workshop . Environ. Health Perspect. , 115 : 1654 – 1659 .
  • Warheit , D. B. , Hoke , R. A. , Finlay , C. , Donner , E. M. , Reed , K. L. and Sayes , C. M. 2007 . Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management . Toxicol. Lett. , 171 : 99 – 110 .
  • Ma-Hock , L. , Gamer , A. O. and Landsiedel , R. 2007 . Generation and characterization of test atmospheres with nanomaterials . Inhal. Toxicol. , 19 : 833 – 848 . et al.
  • Oberdörster , G. , Maynard , A. D. and Donaldson , K. 2005 . Principles for characterizing the potential human health effects from exposure to nanomaterials: Elements of a screening strategy . Part. Fibre Toxicol. , 2 : 8 et al.
  • Powers , K. W. , Brown , S. C. , Krishna , V. B. , Wasdo , S. C. , Moudgil , B. M. and Roberts , S. M. 2006 . Research strategies for safety evaluation of nanomaterials. Part IV. Characterization of nanoscale particles for toxicological evaluation . Toxicol. Sci. , 90 : 296 – 303 .
  • Powers , K. W. , Palazuelos , M. , Moudgil , B. M. and Roberts , S. M. 2007 . Characterization of the size, shape and state of dispersion of nanoparticles for toxicological studies . Nanotoxicology , 1 : 42 – 51 .
  • Maynard , A. D. and Robert , J. A. 2007 . Assessing exposure to airborne nanomaterials: Current abilities and future requirements . Nanotoxicology , 1 : 26 – 41 .
  • Ferin , J. , Oberdorster , G. and Penney , D. P. 1992 . Pulmonary retention of ultrafine and fine particles in rats . Am. J. Respir. Cell. Mol. Biol. , 6 : 535 – 542 .
  • Oberdörster , G. , Ferin , J. , Gelein , R. , Soderholm , S. C. and Finkelstein , J. 1992 . Role of the alveolar macrophage in lung injury: Studies with ultrafine particles . Environ. Health Perspect. , 97 : 193 – 199 .
  • Oberdörster , G. , Ferin , J. and Lehnert , B. E. 1994 . Correlation between particle size, in vivo particle persistence, and lung injury . Environ. Health Perspect. , 102 ( Suppl 5 ) : 173 – 179 .
  • Janssen , Y. M. , Marsh , J. P. , Driscoll , K. E. , Borm , P. J. , Oberdörster , G. and Mossman , B. T. 1994 . Increased expression of manganese-containing superoxide dismutase in rat lungs after inhalation of inflammatory and fibrogenic minerals . Free Radic. Biol. Med. , 16 : 315 – 322 .
  • Heinrich , U. , Fuhst , R. Rittinghausen , S. 1995 . Chronic inhalation exposure of Wistar rats and 2 different strains of mice to diesel-engine exhaust, carbon black, and titanium dioxide . Inhal. Toxicol. , 7 : 533 – 556 .
  • Baggs , R. B. , Ferin , J. and Oberdorster , G. 1997 . Regression of pulmonary lesions produced by inhaled titanium dioxide in rats . Vet. Pathol. , 34 : 592 – 597 .
  • Bermudez , E. , Mangum , J. B. Wong , B. S. 2004 . Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles . Toxicol. Sci. , 77 : 347 – 357 .
  • Geiser , M. , Casaulta , M. , Kupferschmid , B. , Schulz , H. , Semmler-Behnke , M. and Kreyling , W. 2008 . The role of macrophages in the clearance of inhaled ultrafine titanium dioxide particles . Am. J. Respir. Cell. Mol. Biol. , 38 : 371 – 376 .
  • Nurkiewicz , T. R. , Porter , D. W. and Hubbs , A. F. 2008 . Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction . Part. Fibre Toxicol. , 5 : 1 et al.
  • Ma-Hock , L. , Burkhardt , S. and Strauss , V. 2009 . Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance . Inhal. Toxicol. , 21 : 102 – 118 . et al.
  • Rossi , E. M. , Pylkkänen , L. and Koivisto , A. J. 2010 . Airway exposure to silica-coated TiO2 nanoparticules induces pulmonary neutrophilia in mice . Toxicol. Sci. , 113 : 422 – 433 . et al.
  • Warheit , D. B. , Brock , W. J. , Lee , K. P. , Webb , T. R. and Reed , K. L. 2005 . Comparative pulmonary toxicity inhalation and instillation studies with different TiO2 particle formulations: Impact of surface treatments on particle toxicity . Toxicol. Sci. , 88 : 514 – 524 .
  • Leppänen , M. , Korpi , A. and Miettinen , M. 2011 . Nanosized TiO2 caused minor airflow limitation in the murine airways . Arch. Toxicol. , 85 : 827 – 839 . et al.
  • Grassian , V. H. , O’Shaughnessy , P. T. , Adamcakova-Dodd , A. , Pettibone , J. M. and Thorne , P. S. 2007 . Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm . Environ. Health Perspect. , 115 : 397 – 402 .
  • Grassian , V. H. , Adamcakova-Dodd , A. , Pettibone , J. M. , O’Shaughnessy , P. T. and Thorne , P. S. 2007 . Inflammatory response of mice to manufactured titanium dioxide nanoparticles: Comparison of size effects through different exposure routes . Nanotoxicology , 1 : 211 – 226 .
  • Van , R. B. , Landsiedel , R. , Fabian , E. , Burkhardt , S. , Strauss , V. and Ma-Hock , L. 2009 . Comparing fate and effects of three particles of different surface properties: Nano-TiO(2), pigmentary TiO(2) and quartz . Toxicol. Lett. , 186 : 152 – 159 .
  • Preining , E. 1998 . The physical nature of very, very small particles and its impact on their behaviour . J Aerosol Sci. , 29 : 418 – 495 .
  • Domingos , R. F. , Baalousha , M. A. and Ju-Nam , Y. 2009 . Characterizing manufactured nanoparticles in the environment—Multimethod determination of particle sizes . Environ. Sci. Technol. , 43 : 7277 – 7284 . et al.
  • Coudray , N. , Dieterlen , A. , Roth , E. and Trouvé , G. 2009 . Density measurement of fine aerosol fractions from wood combustion sources using ELPI distributions and image processing techniques . Fuel , 88 : 947 – 954 .
  • Isabeta , N. 2007 . Étude expérimentale et modélisation de l’émission d’aérosols ultrafins lors du déversement de poudres nanostructurés . [Experimental Study and Modeling of the Emission of Ultrafine Aerosols in the Discharge of Nanostructured Powders]. Thesis. National Polytechnic Institute of Toulouse, Chemical Engineering, Toulouse, France
  • Morency , F. and Hallé , S. 2010 . “ Modelling nanoparticles transport in an animal exposure chamber: A comparison between numerical and experimental measurements ” . In Advanced in Fluid Mechanics VIII , Edited by: Rahman , M. and Brebbia , C. A. 533 – 544 . Southampton , , U.K : WIT Press .
  • Zhao , B. and Wu , J. 2005 . Numerical investigation of particle diffusion in a clean room . Indoor Built Environ. , 14 : 469 – 479 .
  • Schmoll , L. H. , Elzey , S. , Grassian , V. H. and O’Shaughnessy , P. T. 2009 . Nanoparticle aerosol generation methods from bulk powders for inhalation exposure studies . Nanotoxicology , 3 : 265 – 275 .
  • Kim , S. C. , Chen , D. R. and Qi , C. 2010 . A nanoparticle dispersion method for in vitro and in vivo nanotoxicity study . Nanotoxicology , 4 : 42 – 51 . et al.
  • Valverde , J. M. and Castellanos , A. 2007 . Fluidization, bubbling and jamming of nanoparticle agglomerates . Chem. Eng. Sci. , 62 : 6947 – 6956 .
  • Hinds , W. C. 1999 . Aerosol Technology, Properties, Behavior and Measurement of Airborne Particles , 483 New York : John Wiley & Sons Inc .
  • Hakim , L. F. , Portman , J. L. , Casper , M. D. and Wiemer , A. W. 2005 . Aggregation behavior of nanoparticles in fluidized beds . Powder Technol. , 160 : 149 – 160 .
  • Marjamäki , M. , Keskinen , J. , Chen , D. R. and Pui , D. Y.H. 2000 . Performance evaluation of the electrical low-pressure impactor (ELPI) . J. Aerosol Sci. , 31 : 249 – 261 .
  • Mostofi , R. , Noël , A. , Haghighat , F. , Bahloul , A. , Lara , J. and Cloutier , Y. 2012 . Impact of two particle measurement techniques on the determination of N95 class respirator filtration performance against ultrafine particles . J. Haz. Mat. , 217/218 : 51 – 57 .
  • Jiang , J. , Oberdorster , G. and Biswas , P. 2009 . Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies . J. Nanopart. Res. , 11 : 77 – 89 .
  • Hidy , G. M. 1984 . Aerosols—An Industrial and Environmental Science , London : Academic Press, Inc. .

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