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Research Article

Systemic Therapy for Unresectable Metastatic Melanoma: Impact of Biochemotherapy on Long-Term Survival

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Pages 201-207 | Received 20 Dec 2007, Accepted 12 Mar 2008, Published online: 09 Oct 2008

REFERENCES

  • Ahmann D. L., Creagan E. T., Hahn R. G., Edmonson J. H., Bisel H. F., Schaid D. J. Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma. Cancer 1989; 63: 224–227
  • Allen I. E., Kupelnick B., Kumashiro M., Luo D., Ross S. D., Wolin M. J. Efficacy of interleukin-2 in the treatment of metastatic melanoma: Systematic review and meta-analysis. Cancer Ther. 1998; 1: 168–173
  • Anderson C. M., Buzaid A. C., Legha S. S. Systemic treatments for advanced cutaneous melanoma. Oncology 1995; 9: 1149–1168
  • Atkins M. B., Lee S., Flaherty L. E., Sosman J. A., Sondak V. K., Kirkwood J. M., for the U.S. Melanoma Intergroup. A prospective randomized Phase III trial of concurrent Biochemotherapy (BCT) with cisplatin, Vinblastine, DTIC (CVD), IL-2 and interferon α 2b (IFN) versus CVD alone in patients with metastatic melanoma (E3695): An ECOG-coordinated intergroup trial. Proc. ASCO 2003; 22, (Abstract #2847)
  • Atkins M. B., Lotze M. T., Dutcher J. P., Fisher R. I., Weiss G., Margolin K., Abrams J., Sznol M., Parkinson D., Hawkins M., Paradise C., Kunkel L., Rosenberg S. A. High-dose recombinant interleukin-2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol. 1999; 17: 2105–2116
  • Atkins M. B., O'Boyle K. R., Sosman J. A., Weiss G. R., Margolin K. A., Ernest M. L., Kappler K., Mier J. W., Sparano J. A., Fisher R. I., Eckardt J. R., Pereira C., Aronson F. R. Multi-institutional Phase II trial of intensive combination chemoimmunotherapy for metastatic melanoma. J. Clin. Oncol. 1994; 12: 1553–1560
  • Atzpodien J., Neuber K., Kamanabrou D., Fluck M., Bröcker E. B., Neumann C., Rünger T. M., Schuler G., von den Driesch P., Müller I., Paul E., Patzelt T., Reitz M. Combination chemotherapy with or without subcutaneous IL-2 and 1FNα : Results of a prospectively randomized trial of the Cooperative Advanced Malignant Melanoma Chemoimmunotherapy Group (ACIMM). Br. J. Cancer 2002; 86: 179–184
  • Buzaid A. C., Legha S., Winn R., Belt R., Pollock T., Wiseman C., Ensign L. G. Cisplatin (C), vinblastine (V), DTIC (D) (CVD) versus DTIC alone in metastatic melanoma: Preliminary results Phase III cancer community oncology program (CCOP). Proc. Am. Soc. Clin. Oncol. 1993; 12: 1328, (Abstract #1328)
  • Chapman P. B., Einhorn L. H., Meyers M. L., Saxman S., Destro A. N., Panageas K. S., Begg C. B., Agarwala S. S., Schuchter L. M., Ernstoff M. S., Houghton A. N., Kirkwood J. M. Phase III multi-center randomized trial of the Dartmouth regimen versus DTIC in patients with metastatic melanoma. J. Clin. Oncol. 1999; 17: 2745–2751
  • Cox D. R. Regression models and lifetables. J. Royal Stat. Soc. B 1972; 34: 187–202
  • Del Prete S. A., Maurer L. H., O'Donnell J., Forcier R. J., LeMarbre P. Combination chemotherapy with cisplatin, carmustine, DTIC, and tamoxifen in metastatic melanoma. Cancer Treat. Rep. 1984; 68: 1403–1405
  • Dudley M. E., Wunderlich J. R., Robbins P. F., Yang J. C., Hwu P., Schwartzentruber D. J., Topalian S. L., Sherry R., Restifo N. P., Hubicki A. M., Robinson M. R., Raffeld M., Duray P., Seipp C. A., Rogers-Freezer L., Morton K. E., Mavroukakis S. A., White D. E., Rosenberg S. A. Cancer regression and autoimmunity in patients after clonal repopulation with anti-tumor lymphocytes. Science 2002; 298: 850–854
  • Eton O., Legha S. S., Bedikian A. Y., Lee J. J., Buzaid A. C., Hodges C., Ring S. E., Papadopoulos N. E., Plager C., East M. J., Zhan F., Benjamin R. S. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: Results from a Phase III randomized trial. J. Clin. Oncol. 2002; 20: 2045–2052
  • Flaherty L. E., Atkins M., Sosman J., Weiss G., Clark J. I., Margolin K., Dutcher J., Gordon M. S., Lotze M., Mier J., Sorokin P., Fisher R. I., Appel C., Du W. Outpatient Biochemotherapy with interleukin-2 and interferon-α 2b in patients with metastatic malignant melanoma: Results of two Phase II cytokine working group trials. J. Clin. Oncol. 2001; 19: 3194–3202
  • Hauschild A., Garbe C., Stolz W., Ellwanger U., Seiter S., Dummer R., Ugurel S., Sebastian G., Nashan D., Linse R., Achtelik W, Mohr P., Kaufmann R., Fey M., Ulrich J., Tilgen W. Dacarbazine and interferon-α with or without interleukin 2 in metastatic melanoma: A randomized Phase III multicenter trial of the Dermatologic Oncology Group (DeCOG). Br. J. Cancer 2001; 84: 1036–1042
  • Johnston S. R., Constenia D. O., Moore J., Atkinson H., A'Hern R. P., Dadian G., Riches P. G., Gore M. E. Randomized Phase II trial of BCDT [carmustine (BCNU), cisplatin, DTIC (DTIC), and Tamoxifen] with or without interferon-alpha (IFN〈) and interleukin-2 (IL-2) in patients with metastatic melanoma. Br. J. Cancer 1998; 77: 1280–1286
  • Kaplan E. L., Meier P. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 1958; 53: 457–481
  • Keilholz U., Punt C. J., Gore M., Kruit W., Patel P., Lienard D., Thomas J., Proebstle T. M., Schmittel A., Schadendorf D., Velu T., Negrier S., Kleeberg U., Lehman F., Suciu S., Eggermont A. M. DTIC, cisplatin and interferon-〈 2b with or without interleukin-2 in metastatic melanoma: A randomized Phase III trial (18951) of the European Organization for Research and Treatment of Cancer Melanoma. J. Clin. Oncol. 2005; 23: 6747–6755
  • Khayat D., Borel C., Tourani J. M., Benhammouda A., Antoine E., Rixe O., Vuillemin E., Bazex P. A., Thill L., Franks R., Auclerc G., Soubrane C., Banzet P., Well M. Sequential chemoimmunotherapy with cisplatin, interleukin-2 and interferon-〈 2a for metastatic melanoma. J. Clin. Oncol. 1993; 11: 2173–2180
  • Kim B., Eton O., East M. J., Hodges C., Plager C., Papadopoulos N. E., Rohl C., Grimm E. A., Bedikian A. Y. Pilot study of high dose concurrent biochemotherapy for advanced melanoma. Cancer 2004; 101: 596–603
  • Legha S., Ring S., Bedikian A. Y., Eton O., Plager C., Papadopoulos N. E., Ensign L. G., Benjamin R. S. Lack of benefit from tamoxifen (T) added to a regimen of cisplatin (C), vinblastine (V), DTIC (D) and α -interferon (IFN) in patients (pts) with metastatic melanoma (MM). Proc. Am. Soc. Clin. Oncol. 1993; 12: 388
  • Legha S. S., Ring S., Bedikian A. Y., Plager C., Eton O., Buzaid A. C., Papadopoulos N. E. Treatment of metastatic melanoma with combined chemotherapy containing cisplatin, vinblastine and DTIC (CVD) and biotherapy using interleukin-2 and interferon-α. Ann. Oncol. 1996; 7: 827–835
  • Legha S. S., Ring S., Eton O., Bedikian A., Buzaid A. C., Plager C., Papadopoulos N. Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, DTIC, interferon-α, and interleukin-2 for patients with metastatic melanoma. J. Clin. Oncol. 1998; 16: 1752–1759
  • Legha S. S., Ring S., Eton O., Bedikian A., Plager C., Papadopoulos N. Development and results of biochemotherapy in metastatic melanoma: The University of Texas M.D. Anderson Cancer Center Experience. Cancer J. Sci. Am. 1997; 3: S9–S15
  • Legha S. S., Ring S., Papadopoulos N., Plager C., Chawla S., Benjamin R. A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine, and DTIC (CVD) for metastatic melanoma. Cancer 1989; 64: 2024–2029
  • Lotze M. T., Dallal R. M., Kirkwood J. M., Flickinger J. C. Cutaneous melanoma. Cancer: Principles & Practice of Oncology, 6th Edition, V. T. DeVita, Jr, S. Hellman, S. A. Rosenberg. Lippincott, Williams & Wilkins, Philadelphia 2001; 2:2012–2069
  • Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother. Rep. 1966; 50: 163–170
  • Middleton M. R., Grob J. J., Aaronson N., Fierlbeck G., Tilgen W., Seiter S., Gore M., Aamdal S., Cebon J., Coates A., Dreno B., Henz M., Schadendorf D., Kapp A., Weiss J., Fraass U., Statkevich P., Muller M., Thatcher N. Randomized Phase III study of temozolomide vs. DTIC in the treatment of patients with advanced metastatic malignant melanoma. J. Clin. Oncol. 2000; 18: 158–166
  • Millard M. J., Bedikian A. Y, Conry R. M., Gore M. E., Pehamberger H. E., Sterry W., Pavlick A. C., De Conti R. C., Gordon D., Itri L. M. Randomized multinational Phase 3 trial of DTIC (DTIC) with or without Bcl-2Antisense (oblimersen sodium) in patients (pts) with advanced malignant melanoma (MM): Analysis of long-term survival. Proc. Am. Soc. Clin. Oncol. 2004; 23: 708, (#7505)
  • O'Day S. J., Gammon G., Boasberg P. D., Martin M. A., Kristedja T. S., Guo M., Stern S., Edwards S., Fournier P., Weisberg M., Cannon M., Fawzy N. W., Johnson T. D., Essner R., Foshag L. J., Morton D. L. Advantages of concurrent Biochemotherapy modified by decrescendo interleukin-2, granulocyte colony-stimulating factor, and tamoxifen for patients with metastatic melanoma. J. Clin. Oncol. 1999; 17: 2752–2761
  • Papadopoulos N., Bedikian A. Y., Ring S., Kim K. B., Camacho L. H., Eton O. Phase II study of CTD (cisplatin, paclitaxel, DTIC) in metastatic melanoma (MM). Proc. Am. Soc. Clin. Oncol. 2003; 22, (Abstract #2889)
  • Richards J. M., Mehta N., Ramming K., Skosey P. Sequential chemoimmunotherapy in treatment of metastatic melanoma. J. Clin. Oncol. 1992; 10: 1338–1343
  • Rosenberg S. A., Yang J. C., Schwartzentruber D. J., Hwu P., Marincola F. M., Topalian S. L., Seipp C. A., Einhorn J. H., White D. E., Steinberg S. M. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, DTIC, and tamoxifen alone or in combination with interleukin-2 and interferon α 2b. J. Clin. Oncol. 1999; 17: 968–975
  • Rosenberg S. A., Yang J. C., Topalian S. L., Schwartzentruber D. J., Weber J. S., Parkinson D. R., Seipp C. A., Einhorn J. H., White D. E. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin-2. JAMA 1994; 271: 907–913
  • Thompson J. A., Gold P. J., Fefer A. Outpatient chemoimmunotherapy for the treatment of metastatic melanoma. Sem. Oncol. 1997; 24(S14)S44–S48
  • WHO. World Health Organization. Handbook for Reporting Results of Cancer Treatment. World Health Organization, Geneva 1979
  • Yee C., Thompson J. A., Byrd D., Riddell S. R., Roche P., Celis E., Greenberg P. D. Adoptive T-cell therapy using antigen-specific CD8+ T-cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and anti-tumor effect of transferred T-cells. Proc. Natl. Acad. Sci. USA 2002; 99: 16168–16173
  • Zitvogel L., Apetoh L., Ghiringhelli F., Kroemer G. Immunological aspects of cancer chemotherapy. Nature Med. 2008; 8: 59–73

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