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Research Articles

Improvement and optimization of a T-cell-dependent antibody response (TDAR) method for BALB/c mice using keyhole limpet hemocyanin (KLH) as specific antigen

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Pages 149-154 | Received 15 Mar 2019, Accepted 19 Jun 2019, Published online: 10 Jul 2019

References

  • Bugelski P, Kim C. 2007. T-Dependent antigen response (TDAR) tests: Meta-analysis of results generated across multiple laboratories. J Immunotoxicol. 4:159–164.
  • Chen L, Qi Y, Qi Z, Gao K, Gong R, Shao Z, Liu S, Li S, Sun Y. 2019. A comparative study on the effects of different parts of panax ginseng on the immune activity of cyclophosphamide-induced immunosuppressed mice. Molecules. 4:1096.
  • Ferbas J, Belouski S, Horner M, Kaliyaperumal A, Chen L, Boyce M, Colaço C, McHugh N, Quick V, Nicholl R. 2013. A novel assay to measure B-cell responses to keyhole limpet hemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus. Br J Clin Pharmacol. 76:188–202.
  • Gallegos A, Hoerger M, Talbot N, Krasner M, Knight J, Moynihan J, Duberstein P. 2013. Toward identifying effects of specific components of mindfulness-based stress reduction on biologic and emotional outcomes among older adults. J Alternat Complement Med. 19:787–792.
  • Gehen SC, Blacker AM, Boverhof DR, Hanley TR, Hastings CE, Ladics GS, Lu H, O’Neal FO. 2014. Retrospective evaluation of impact of functional immunotoxicity testing on pesticide hazard identification and risk assessment. Crit Rev Toxicol. 44:407–419.
  • Kawai R, Ito S, Aida T, Hattori H, Kimura T, Furukawa T, Mori K, Sanbuissho A, Kawada T. 2013. Evaluation of primary and secondary responses to a T-cell-dependent antigen, keyhole limpet hemocyanin, in rats. J Immunotoxicol. 10:40–48.
  • Ladics G. 2018. The sheep erythrocyte T-dependent antibody response (TDAR). Methods Mol Biol. 1803:83–94.
  • Lebrec H, Hock M, Sundsmo J, Mytych D, Chow H, Carlock L, Joubert M, Reindel J, Zhou L, Bussiere J. 2014. T-Cell-dependent antibody responses in the rat: Forms and sources of keyhole limpet hemocyanin matter. J Immunotoxicol. 11:213–221.
  • Lebrec H, Molinier B, Boverhof D, Collinge M, Freebern W, Henson K, Mytych DT, Ochs HD, Wange R, Yang Y, et al. 2014. The T-cell-dependent antibody response assay in non-clinical studies of pharmaceuticals and chemicals: Study design, data analysis, interpretation. Regul Toxicol Pharmacol. 69:7–21.
  • Peachee V, Smith M, Beck M, Stump D, White K. 2014. Characterization of the T-dependent antibody response (TDAR) to keyhole limpet hemocyanin (KLH) in the Göttingen minipig. J Immunotoxicol. 11:376–382.
  • Plitnick L, Herzyk D. 2010. The T-dependent antibody response to keyhole limpet hemocyanin in rodents. Methods Mol Biol. 598:159–171.
  • Potter T, Neun B, Dobrovolskaia M. 2018. Methods for analysis of nanoparticle immunosup- pressive properties in vitro and in vivo. Meth Mol Biol. 1682:161–172.
  • Rhodes M, Laffan S, Genell C, Gower J, Maier C, Fukushima T, Nichols G, Bassiri A. 2012. Assessing a theoretical risk of dolutegravir-induced developmental immunotoxicity in juvenile rats. Toxicol Sci. 130:70–81.
  • Swaminathan A, Lucas R, Dear K, McMichael A. 2014. Keyhole limpet haemocyanin – a model antigen for human immunotoxicological studies. Br J Clin Pharmacol. 78:1135–1142.
  • Vandebriel R, Tonk E, De la Fonteyne-Blankestijn L, Gremmer E, Verharen H, van der Ven L, van Loveren H, de Jong W. 2014. Immunotoxicity of silver nanoparticles in an intravenous 28-day repeated-dose toxicity study in rats. Part Fibre Toxicol. 11:21.