601
Views
12
CrossRef citations to date
0
Altmetric
Clinical Research

Glucose-insulin-potassium infusion for the treatment of acute aluminum phosphide poisoning: an open-label pilot study

, , , , &
Pages 1004-1009 | Received 30 Sep 2019, Accepted 15 Jan 2020, Published online: 04 Mar 2020

References

  • Murali R, Bhalla A, Singh D, et al. Acute pesticide poisoning: 15 years experience of a large North-West Indian hospital. Clin Toxicol. 2009;47(1):35–38.
  • Eddleston M, Phillips MR. Self poisoning with pesticides. BMJ. 2004;328(7430):42–44.
  • Jeyaratnam J. Acute pesticide poisoning: a major global health problem. World Health Stat Q. 1990;43(3):139–144.
  • Hackenberg U. Chronic ingestion by rats of standard diet treated with aluminum phosphide. Toxicol Appl Pharmacol. 1972;23(1):147–158.
  • Abder-Rahman HA, Battah AH, Ibraheem YM, et al. Aluminum phosphide fatalities, new local experience. Med Sci Law. 2000;40(2):164–168.
  • Siwach SB, Gupta A. The profile of acute poisonings in Harayana-Rohtak Study. J Assoc Physicians India. 1995;43(11):756–759.
  • Gupta SK, Peshin SS, Srivastava A, et al. A study of childhood poisoning at National Poisons Information Centre, All India Institute of Medical Sciences, New Delhi. J Occup Health. 2003;45(3):191–196.
  • Chugh SN, Dushyant RS, et al. Incidence & outcome of aluminium phosphide poisoning in a hospital study. Indian J Med Res. 1991;94:232–235.
  • Chugh SN, Jaggal KL, Sharma A, et al. Magnesium levels in acute cardiotoxicity due to aluminium phosphide poisoning. Indian J Med Res. 1991;94:437–439.
  • Chugh SN, Chugh K, Ram S, et al. Electrocardiographic abnormalities in aluminium phosphide poisoning with special reference to its incidence, pathogenesis, mortality and histopathology. J Indian Med Assoc. 1991;89(2):32–35.
  • Shadnia S, Mehrpour O, Soltaninejada K. Simplified acute physiology score in the prediction of acute aluminum phosphide poisoning outcome. Indian J Med Sci. 2010;64:532–539.
  • Gurjar M, Baronia AK, Azim A, et al. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4(3):378–384.
  • Moghadamnia AA. An update on toxicology of aluminum phosphide. Daru. 2012;20(1):25.
  • Singh S, Bhalla A, Verma SK, et al. Cytochrome-c oxidase inhibition in 26 aluminum phosphide poisoned patients. Clin Toxicol. 2006;44(2):155–158.
  • Proudfoot AT. Aluminium and zinc phosphide poisoning. Clin Toxicol. 2009;47(2):89–100.
  • Goel A, Aggarwal P. Pesticide poisoning. Natl Med J India. 2007;20(4):182–191.
  • Bolter CJ, Chefurka W. Extramitochondrial release of hydrogen peroxide from insect and mouse liver mitochondria using the respiratory inhibitors phosphine, myxothiazol, and antimycin and spectral analysis of inhibited cytochromes. Arch Biochem Biophys. 1990;278(1):65–72.
  • Chugh SN, Arora V, Sharma A, et al. Free radical scavengers & lipid peroxidation in acute aluminium phosphide poisoning. Indian J Med Res. 1996;104:190–193.
  • Alter P, Grimm W, Maisch B. Lethal heart failure caused by aluminium phosphide poisoning. Intensive Care Med. 2001;27(1):327–327.
  • Ragone S, Bernstein J, Lew E, et al. Fatal aluminum phosphide ingestion. J Toxicol Clin Toxicol. 2002;40:690.
  • Akkaoui M, Achour S, Abidi K, et al. Reversible myocardial injury associated with aluminum phosphide poisoning. Clin Toxicol. 2007;45(6):728–731.
  • Katira R, Elhence GP, Mehrotra ML, et al. A study of aluminum phosphide (AlP) poisoning with special reference to electrocardiographic changes. J Assoc Physicians India. 1990;38(7):471–473.
  • Sinha US, Kapoor AK, Singh AK, et al. Histopathological changes in cases of aluminium phosphide poisoning. Indian J Pathol Microbiol. 2005;48(2):177–180.
  • Kalra GS, Anand IS, Jit I, et al. Aluminium phosphide poisoning: haemodynamic observations. Indian Heart J. 1991;43(3):175–178.
  • Chugh SN, Kishore K, Prakash V. Multisystem organ failure in acute aluminium phosphide poisoning. J Assoc Physicians India. 1998;46(11):983.
  • Chugh SN, Ram S, Mehta LK, et al. Adult respiratory distress syndrome following aluminium phosphide ingestion. Report of 4 cases. J Assoc Physicians India. 1989;37(4):271–272.
  • Agrawal VK, Bansal A, Singh RK, et al. Aluminum phosphide poisoning: possible role of supportive measures in the absence of specific antidote. Indian J Crit Care Med. 2015;19(2):109–112.
  • Bajwa SJS, Bajwa SK, Kaur J, et al. Management of celphos poisoning with a novel intervention: a ray of hope in the darkest of clouds. Anesth Essays Res. 2010;4(1):20–24.
  • Shadnia S, Rahimi M, Pajoumand A, et al. Successful treatment of acute aluminium phosphide poisoning: possible benefit of coconut oil. Hum Exp Toxicol. 2005;24(4):215–218.
  • Chugh SN, Kamar P, Sharma A, et al. Magnesium status and parenteral magnesium sulphate therapy in acute aluminum phosphide intoxication. Magnes Res. 1994;7(3–4):289–294.
  • Chugh SN, Kumar P, Aggarwal HK, et al. Efficacy of magnesium sulphate in aluminium phosphide poisoning-comparison of two different dose schedules. J Assoc Physicians India. 1994;42(5):373–375.
  • Hassanian-Moghaddam H, Shahbazi A. Gastric ventilation: a new approach to metal phosphide fumigant ingestion. Clin Toxicol. 2012;50(5):435–437.
  • Bhalla A, Jyothinath P, Singh S. Antioxidant therapy in patients with severe aluminum phosphide poisoning: a pilot study. Indian J Crit Care Med. 2017;21(12):836–840.
  • Baruah U, Sahni A, Sachdeva HC. Successful management of aluminium phosphide poisoning using intravenous lipid emulsion: report of two cases. Indian J Crit Care Med. 2015;19(12):735–738.
  • Zamani N, Hassanian-Moghaddam H, Ebrahimi S. Whole blood exchange transfusion as a promising treatment of aluminium phosphide poisoning. Arh Hig Rada Toksikol. 2018;69(3):275–277.
  • Hassanian-Moghaddam H, Zamani N, Rahimi M, et al. Successful treatment of aluminium phosphide poisoning by extracorporeal membrane oxygenation. Basic Clin Pharmacol Toxicol. 2016;118(3):243–246.
  • Hashemi-Domeneh B, Zamani N, Hassanian-Moghaddam H, et al. A review of aluminium phosphide poisoning and a flowchart to treat it. Arh Hig Rada Toksikol. 2016;67(3):183–193.
  • Kline JA, Raymond RM, Leonova ED, et al. Insulin improves heart function and metabolism during non-ischemic cardiogenic shock in awake canines. Cardiovasc Res. 1997;34(2):289–298.
  • Kerns W, 2nd, Schroeder D, Williams C, et al. Insulin improves survival in a canine model of acute beta-blocker toxicity. Ann Emerg Med. 1997;29(6):748–757.
  • Yuan TH, Kerns WP, 2nd, Tomaszewski CA, et al. Insulin-glucose as adjunctive therapy for severe calcium channel antagonist poisoning. J Toxicol Clin Toxicol. 1999;37(4):463–474.
  • Mégarbane B, Karyo S, Baud FJ. The role of insulin and glucose (hyperinsulinaemia/euglycaemia) therapy in acute calcium channel antagonist and beta-blocker poisoning. Toxicol Rev. 2004;23(4):215–222.
  • Shepherd G, Klein-Schwartz W. High-dose insulin therapy for calcium-channel blocker overdose. Ann Pharmacother. 2005;39(5):923–930.
  • Kerns W. 2nd, Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007;25(2):309–331.
  • Kalay N, Ozdogru I, Gul A, et al. Effects of intermittent and long-term glucose-insulin-potassium infusion in patients with systolic heart failure. Exp Clin Cardiol. 2008;13(2):85–88.
  • Xu J, Zou MH. Molecular insights and therapeutic targets for diabetic endothelial dysfunction. Circulation. 2009;120(13):1266–1286.
  • Rains JL, Jain SK. Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med. 2011;50(5):567–575.
  • Engebretsen KM, Kaczmarek KM, Morgan J, et al. High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning. Clin Toxicol. 2011;49(4):277–283.
  • Holger JS, Stellpflug SJ, Cole JB, et al. High-dose insulin: a consecutive case series in toxin-induced cardiogenic shock. Clin Toxicol. 2011;49(7):653–658.
  • Woodward C, Pourmand A, Mazer-Amirshahi M. High dose insulin therapy, an evidence based approach to beta blocker/calcium channel blocker toxicity. Daru. 2014;22(1):36.
  • Jang DH, Spyres MB, Fox L, et al. Toxin-induced cardiovascular failure. Emerg Med Clin North Am. 2014;32(1):79–102.
  • Mehrpour O, Alfred S, Shadnia S, et al. Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor. Hum Exp Toxicol. 2008;27(7):591–595.
  • Hassanian-Moghaddam H. Probable benefit of hyperinsulinemia-euglycemia and hyperventilation oxygenation on aluminium phosphide poisoning. Abstracts of the 2008 North American Congress of Clinical Toxicology Annual Meeting, September 11–16, 2008, Toronto, Canada. Clin Toxicol. 2008;46(7):592.
  • Hassanian-Moghaddam H, Zamani N. Therapeutic role of hyperinsulinemia/euglycemia in aluminum phosphide poisoning. Medicine. 2016;95(31):e4349.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.