RHODOSTOMIN, A SNAKE VENOM DISINTEGRIN, SERVED AS A MOLECULAR TOOL TO DISSECT THE INTEGRIN FUNCTION

References

• Abrams C. S. Intracellular signaling in platelets. Curr. Opin. Hematol. 2005; 12: 401–405
   PubMed Web of Science ®Google Scholar
• Artenstein A. W., Opal S. M., Cristofaro P., Palardy J. E., Parejo N. A., Green M. D., Jhung J. W. Chloroquine enhances survival in Bacillus anthracis intoxication. J. Infect. Dis. 2004; 190: 1655–1660
   PubMed Web of Science ®Google Scholar
• Ashburn P. M., Craig C. F. Experimental investigations regarding the etiology of dengue fever. 1907. J. Infect. Dis. 2004; 189: 1744–1746, 1747–1783; discussion
   Google Scholar
• Audi J., Belson M., Patel M., Schier J., Osterloh J. Ricin poisoning: a comprehensive review. JAMA 2005; 294: 2342–2351
   PubMed Web of Science ®Google Scholar
• Calvete J. J., Moreno-Murciano M. P., Theakston R. D., Kisiel D. G., Marcinkiewicz C. Snake venom disintegrins: novel dimeric disintegrins and structural diversification by disulphide bond engineering. Biochem. J. 2003; 372: 725–734
   PubMed Web of Science ®Google Scholar
• Calvete J. J., Marcinkiewicz C., Monleon D., Esteve V., Celda B., Juarez P., Sanz L. Snake venom disintegrins: evolution of structure and function. Toxicon 2005; 45: 1063–1074
   PubMed Web of Science ®Google Scholar
• Chang C. P., Chang J. C., Chang H. H., Tsai W. J., Lo S. J. Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3. Biochem. J. 2001; 357: 57–64
   PubMedGoogle Scholar
• Chang H. H., Lo S. J. Full-spreading platelets induced by the recombinant rhodostomin are via binding to integrins and correlated with FAK phosphorylation. Toxicon 1998; 36: 1087–1099
   PubMedGoogle Scholar
• Chang H. H., Lo S. J. Modification with a phosphorylation tag of PKA in the TraT-based display vector of Escherichia coli. J. Biotechnol. 2000; 78: 115–122
   PubMedGoogle Scholar
• Chang H. H., Tsai W. J., Lo S. J. Glutathione S-transferase-rhodostomin fusion protein inhibits platelet aggregation and induces platelet shape change. Toxicon 1997a; 35: 195–204
   PubMedGoogle Scholar
• Chang H. H., Sheu S. Y., Lo S. J. Expression of foreign antigens on the surface of Escherichia coli by fusion to the outer membrane protein traT. J. Biomed. Sci. 1999a; 6: 64–70
   PubMedGoogle Scholar
• Chang H. H., Lin C. H., Lo S. J. Recombinant rhodostomin substrates induce transformation and active calcium oscillation in human platelets. Exp. Cell Res. 1999b; 250: 387–400
   PubMed Web of Science ®Google Scholar
• Chang H. H., Shih K. N., Lo S. J. Receptor-mediated endocytosis as a selection force to enrich bacteria expressing rhodostomin on their surface. J. Biomed. Sci. 2000; 7: 42–50
   PubMedGoogle Scholar
• Chang H. H., Kau J. H., Lo S. J., Sun D. S. Cell-adhesion and morphological changes are not sufficient to support anchorage-dependent cell growth via non-integrin-mediated attachment. Cell Biol. Int. 2003; 27: 123–133
   PubMedGoogle Scholar
• Chang H. H., Chang C. P., Chang J. C., Dung S. Z., Lo S. J. Application of recombinant rhodostomin in studying cell adhesion. J. Biomed. Sci. 1997b; 4: 235–243
   PubMed Web of Science ®Google Scholar
• Chang H. H., Hu S. T., Huang T. F., Chen S. H., Lee Y. H., Lo S. J. Rhodostomin, an RGD-containing peptide expressed from a synthetic gene in Escherichia coli, facilitates the attachment of human hepatoma cells. Biochem. Biophys. Res. Commun. 1993; 190: 242–249
   PubMed Web of Science ®Google Scholar
• Chang H. H., Shyu H. F., Wang Y. M., Sun D. S., Shyu R. H., Tang S. S., Huang Y. S. Facilitation of cell adhesion by immobilized dengue viral nonstructural protein 1 (NS1): arginine-glycine-aspartic acid structural mimicry within the dengue viral NS1 Antigen. J. Infect. Dis. 2002; 186: 743–751
   PubMed Web of Science ®Google Scholar
• Chang J. C., Chang H. H., Lin C. T., Lo S. J. The integrin alpha 6beta 1 modulation of PI3 K and Cdc42 activities induces dynamic filopodium formation in human platelets. J. Biomed. Sci. 2005; 12: 881–898
   PubMedGoogle Scholar
• Chang M. C., Wang B. R., Huang T. F. Characterization of endothelial cell differential attachment to fibrin and fibrinogen and its inhibition by Arg-Gly-Asp-containing peptides. Thromb. Haemost. 1995; 74: 764–769
   PubMedGoogle Scholar
• Changeux J. P. The visit of professor Chen-Yuan Lee to the Pasteur institute in 1970 and the use of a snake venom toxin to identify the acetylcholine receptor protein. Toxin Reviews 2005; 24: 15–41
   Web of Science ®Google Scholar
• Chen L. W., Lin M. W., Hsu C. M. Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils. J. Biomed. Sci. 2005; 12: 311–319
   PubMedGoogle Scholar
• Cheng T. H., Shih N. L., Chen C. H., Lin H., Liu J. C., Chao H. H. Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced beta-myosin heavy chain gene expression and cardiomyocyte hypertrophy. J. Biomed. Sci. 2005; 12: 123–133
   PubMedGoogle Scholar
• Chiang H. S., Yang R. S., Huang T. F. The Arg-Gly-Asp-containing peptide, rhodostomin, inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells. Br. J. Cancer 1995; 71: 265–270
   PubMedGoogle Scholar
• Chiou S. H., Chen Y. S. Characterization of two major families of fibrinogenolytic proteases from the venom of Taiwan habu with special reference to their medical applications. Toxin Reviews 2005; 24: 43–61
   Web of Science ®Google Scholar
• Chiung Y. M., Kao Y. Y., Chen H. T., Liu P. S. Inhibition by 2,4-toluene diisocyanate of the calcium signaling of neuronal nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells. J. Biomed. Sci. 2005; 12: 539–546
   PubMedGoogle Scholar
• Cui X., Li Y., Moayeri M., Choi G. H., Subramanian G. M., Li X. Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis. J. Infect. Dis. 2005; 191: 422–434
   PubMed Web of Science ®Google Scholar
• Diochot S. Precious natural peptides from spider venoms: new tools for studying potassium channels. Toxin Reviews 2005; 24: 289–312
   Web of Science ®Google Scholar
• Dixit A., Dhaked R. K., Alam S. I., Singh L. Military potential of biological neurotoxins. Toxin Reviews 2005; 24: 175–207
   Web of Science ®Google Scholar
• Dixon T. C., Meselson M., Guillemin J., Hanna P. C. Anthrax. N. Engl. J. Med. 1999; 341: 815–826
   PubMed Web of Science ®Google Scholar
• Dorsam R. T., Kunapuli S. P. Central role of the P2Y12 receptor in platelet activation. J. Clin. Invest 2004; 113: 340–345
   PubMed Web of Science ®Google Scholar
• Duesbery N. S., Webb C. P., Leppla S. H., Gordon V. M., Klimpel K. R., Copeland T. D. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 1998; 280: 734–737
   PubMed Web of Science ®Google Scholar
• During R. L., Li W., Hao B., Koenig J. M., Stephens D. S., Quinn C. P., Southwick F. S. Anthrax lethal toxin paralyzes neutrophil actin-based motility. J. Infect. Dis. 2005; 192: 837–845
   PubMed Web of Science ®Google Scholar
• Endy T. P., Nisalak A., Chunsuttitwat S., Vaughn D. W., Green S., Ennis F. A. Relationship of preexisting dengue virus (DV) neutralizing antibody levels to viremia and severity of disease in a prospective cohort study of DV infection in Thailand. J. Infect. Dis. 2004; 189: 990–1000
   PubMed Web of Science ®Google Scholar
• Hardy A. R., Jones M. L., Mundell S. J., Poole A. W. Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets. Blood 2004; 104: 1745–1752
   PubMed Web of Science ®Google Scholar
• Hou R. C., Chen Y. S., Chen C. H., Chen Y. H., Jeng K. C. Protective effect of 1,2,4-benzenetriol on LPS-induced NO production by BV2 microglial cells. J. Biomed. Sci. 2005; 12: 1–11
   Google Scholar
• Huang T. F., Yeh C. H., Wu W. B. Viper venom components affecting angiogenesis. Haemostasis 2001; 31: 192–206
   PubMedGoogle Scholar
• Huang T. F., Holt J. C., Lukasiewicz H., Niewiarowski S. Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex. J. Biol. Chem. 1987; 262: 16157–16163
   PubMed Web of Science ®Google Scholar
• Hynes S. O., Wadstrom T. Toxins of the helicobacter genus and their roles in pathogenesis. J. Toxicol. 2004; 23: 1–35
   Google Scholar
• Jiang S. J., Lin T. M., Shi G. Y., Eng H. L., Chen H. Y., Wu H. L. Inhibition of bovine herpesvirus-4 replication by arsenite through downregulation of the extracellular signal-regulated kinase signaling pathway. J. Biomed. Sci. 2004; 11: 500–510
   PubMedGoogle Scholar
• Jones M. B., Jani R., Ren D., Wood T. K., Blaser M. J. Inhibition of Bacillus anthracis growth and virulence-gene expression by inhibitors of quorum-sensing. J. Infect. Dis. 2005; 191: 1881–1888
   PubMed Web of Science ®Google Scholar
• Kao Y. S., Fong J. C. Thapsigargin and EGTA inhibit endothelin-1-induced glucose transport. J. Biomed. Sci. 2004; 11: 206–213
   PubMedGoogle Scholar
• Kau J. H., Sun D. S., Tsai W. J., Shyu H. F., Huang H. H., Lin H. C., Chang H. H. Antiplatelet activities of anthrax lethal toxin are associated with suppressed p42/44 and p38 mitogen-activated protein kinase pathways in the platelets. J. Infect. Dis. 2005; 192: 1465–1474
   PubMed Web of Science ®Google Scholar
• Kawai N. Spider polyamine toxin. Toxin Reviews 2005; 24: 271–287
   Web of Science ®Google Scholar
• Lin C. C., Sun C. C., Luo S. F., Tsai A. C., Chien C. S., Hsiao L. D. Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB. J. Biomed. Sci. 2004; 11: 377–390
   PubMedGoogle Scholar
• Lin Y. R., Kao P. C., Chan M. H. Involvement of Ca2+ signaling in tachykinin-mediated contractile responses in swine trachea. J. Biomed. Sci. 2005a; 12: 547–558
   PubMedGoogle Scholar
• Lin Y. T., Tang C. H., Chuang W. J., Wang S. M., Huang T. F., Fu W. M. Inhibition of adipogenesis by RGD-dependent disintegrin. Biochem. Pharmacol. 2005b; 70: 1469–1478
   PubMedGoogle Scholar
• Lo I. C., Shih J. M., Jiang M. J. Reactive oxygen species and ERK 1/2 mediate monocyte chemotactic protein-1-stimulated smooth muscle cell migration. J. Biomed. Sci. 2005; 12: 377–388
   PubMed Web of Science ®Google Scholar
• Lo S. J., Chang H. H. Recombinant snake disintegrins used for mammalian integrin study. Toxin Reviews 2005; 24: 95–111
   Web of Science ®Google Scholar
• Markland F. S., Swenson S., Costa F., Minea R., Sherwin R. P., Yang D. A snake venom disintegrin with potent antitumor and antiangiogenic activity. Toxin Reviews 2005; 24: 113–142
   Web of Science ®Google Scholar
• Mazzucato M., Cozzi M. R., Pradella P., Ruggeri Z. M., De Marco L. Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow. Blood 2004; 104: 3221–3227
   PubMed Web of Science ®Google Scholar
• Miyoshi S., Morita A., Teranishi T., Tomochika K., Yamamoto S., Shinoda S. An exocellular cytolysin produced by Vibrio vulnificus cdc b3547, a clinical isolate in biotype 2 (serovar e). J. Toxicol. 2004; 23: 111–121
   Google Scholar
• Nguyen T. H., Lei H. Y., Nguyen T. L., Lin Y. S., Huang K. J., Le B. L. Dengue hemorrhagic fever in infants: a study of clinical and cytokine profiles. J. Infect. Dis. 2004; 189: 221–232
   PubMed Web of Science ®Google Scholar
• Palma M. S., Nakajima T. A natural combinatorial chemistry strategy in acylpolyamine toxins from nephilinae orb-web spiders. Toxin Reviews 2005; 24: 209–234
   Web of Science ®Google Scholar
• Quinn C. P., Dull P. M., Semenova V., Li H., Crotty S., Taylor T. H. Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax. J. Infect. Dis. 2004; 190: 1228–1236
   PubMed Web of Science ®Google Scholar
• Schlondorff J., Blobel C. P. Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J. Cell Sci. 1999; 112: 3603–3617
   PubMed Web of Science ®Google Scholar
• Scobie H. M., Thomas D., Marlett J. M., Destito G., Wigelsworth D. J., Collier R. J. A soluble receptor decoy protects rats against anthrax lethal toxin challenge. J. Infect. Dis. 2005; 192: 1047–1051
   PubMed Web of Science ®Google Scholar
• Silverman J. A., Mortin L. I., Vanpraagh A. D., Li T., Alder J. Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impact. J. Infect. Dis. 2005; 191: 2149–2152
   PubMed Web of Science ®Google Scholar
• Sun D. S., Lo S. J., Lin C. H., Yu M. S., Huang C. Y., Chen Y. F., Chang H. H. Calcium oscillation and phosphatidylinositol 3-kinase positively regulate integrin alpha(IIb)beta3-mediated outside-in signaling. J. Biomed. Sci. 2005a; 12: 321–333
   PubMedGoogle Scholar
• Sun D. S., Lo S. J., Tsai W. J., Lin C. H., Yu M. S., Chen Y. F., Chang H. H. PI3-kinase is essential for ADP-stimulated integrin alpha(IIb)beta3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin alpha(IIb)beta3-initiated signaling cross-talks. J. Biomed. Sci. 2005b; 12: 937–948
   PubMedGoogle Scholar
• Suter D. M., Errante L. D., Belotserkovsky V., Forscher P. The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling. J. Cell Biol. 1998; 141: 227–240
   PubMedGoogle Scholar
• Thompson C., Lin C. H., Forscher P. An Aplysia cell adhesion molecule associated with site-directed actin filament assembly in neuronal growth cones. J. Cell Sci. 1996; 109: 2843–2854
   PubMedGoogle Scholar
• Titball R. W., Basak A. K. The bacterial zinc-metallophospholipases c. Journal of Toxicology. Toxin Reviews 2004; 23: 509–554
   Google Scholar
• Trochon-Joseph V., Martel-Renoir D., Mir L. M., Thomaidis A., Opolon P. Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin. Cancer Res. 2004; 64: 2062–2069
   PubMed Web of Science ®Google Scholar
• Tsai I. H. Revised systematics of Taiwanese Viperid snakes and the correlation to venom diversity and evolution. Toxin Reviews 2005; 24: 63–78
   Web of Science ®Google Scholar
• Tseng Y. L., Peng H. C., Huang T. F. Rhodostomin, a disintegrin, inhibits adhesion of neutrophils to fibrinogen and attenuates superoxide production. J. Biomed. Sci. 2004; 11: 683–691
   PubMedGoogle Scholar
• Tu A. T. Snake venom symposium in honor of professor C. Y. Lee lecture by A. T. Tu on october 31, 2003: snake venom research in Taiwan before 1945 (during Japanese colonial days). Toxin Reviews 2005; 24: 1–13
   Web of Science ®Google Scholar
• Tu A. T., Motoyashiki T., Azimov D. A. Bioactive compounds in tick and mite venoms (saliva). Toxin Reviews 2005; 24: 143–174
   Web of Science ®Google Scholar
• Wang J. S., Tang L. Epidemiology of aflatoxin exposure and human liver cancer. J. Toxicol. 2004; 23: 249–271
   Web of Science ®Google Scholar
• Wu W. S., Hua J. M. Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2. J. Biomed. Sci. 2005; 12: 289–296
   PubMedGoogle Scholar
• Wills B. A., Oragui E. E., Dung N. M., Loan H. T., Chau N. V., Farrar J. J., Levin M. Size and charge characteristics of the protein leak in dengue shock syndrome. J. Infect. Dis. 2004; 190: 810–818
   PubMed Web of Science ®Google Scholar
• Wiwanitkit V. A review of the hematologic effects of green pit viper venom. J. Toxicol. 2004; 23: 105–110
   Google Scholar
• Wu W. B., Peng H. C., Huang T. F. Disintegrin causes proteolysis of beta-catenin and apoptosis of endothelial cells. Involvement of cell-cell and cell-ECM interactions in regulating cell viability. Exp. Cell Res. 2003; 286: 115–127
   PubMedGoogle Scholar
• Yang R. S., Chiang H. S., Tang C. H., Yeh C. S., Huang T. F. Rhodostomin inhibits thrombin-enhanced adhesion of ROS 17/2.8 cells through the blockade of alphavbeta3 integrin. Toxicon 2005a; 46: 387–393
   PubMedGoogle Scholar
• Yang R. S., Tang C. H., Chuang W. J., Huang T. H., Peng H. C., Huang T. F., Fu W. M. Inhibition of tumor formation by snake venom disintegrin. Toxicon 2005b; 45: 661–669
   PubMed Web of Science ®Google Scholar
• Yeh C. H., Peng H. C., Huang T. F. Cytokines modulate integrin alpha(v)beta(3)-mediated human endothelial cell adhesion and calcium signaling. Exp. Cell Res. 1999; 251: 57–66
   PubMedGoogle Scholar