288
Views
49
CrossRef citations to date
0
Altmetric
Original Research

Clinical cosmeceutical repurposing of melatonin in androgenic alopecia using nanostructured lipid carriers prepared with antioxidant oils

, ORCID Icon, , , &
Pages 927-935 | Received 08 Feb 2018, Accepted 27 Aug 2018, Published online: 10 Sep 2018

References

  • Norwood OT. Male pattern baldness: classification and incidence. South Med J. 1975;68:1359–1365.
  • Naito A, Midorikawa T, Yoshino T, et al. Lipid peroxides induce early onset of catagen phase in murine hair cycles. Int J Mol Med. 2008;22:725–729.
  • Mosley JG, Gibbs CC. Premature grey hair and hair loss among smokers: a new opportunity for health education. BMJ. 1996;313:1616.
  • Prie BE, Iosif L, Tivig I, et al. Oxidative stress in androgenetic alopecia. J Med Life. 2016;9:79–83.
  • Nasr M, Mansour S, Mortada ND, et al. Vesicular aceclofenac systems: a comparative study between liposomes and niosomes. J Microencapsul. 2008;25:499–512.
  • Nasr M, Mansour S, Mortada ND, et al. Lipospheres as carriers for topical delivery of aceclofenac: preparation, characterization and in vivo evaluation. AAPS PharmSciTech. 2008;9:154–162.
  • Bseiso EA, Nasr M, Sammour O, et al. Recent advances in topical formulation carriers of antifungal agents. Indian J Dermatol Venereol Leprol. 2015;81:457–463.
  • Nasr M, Abdel-Hamid S. Lipid based nanocapsules: a multitude of biomedical applications. Curr Pharm Biotechnol. 2015;16:322–332.
  • Abdelgawad R, Nasr M, Moftah NH, et al. Phospholipid membrane tabulation using ceramide doping “cerosomes”: characterization and clinical application in psoriasis treatment. Eur J Pharm Sci. 2017;101:258–268.
  • Loo CH, Basri M, Ismail R, et al. Effect of compositions in nanostructured lipid carriers (NLC) on skin hydration and occlusion. Int J Nanomed. 2012;8:13–22.
  • Lacatusu I, Badea N, Ovidiu O, et al. Highly antioxidant carotene lipid nanocarriers: synthesis and antibacterial activity. J Nanopart Res. 2012;14:902.
  • Reiter RJ, Mayo JC, Tan DX, et al. Melatonin as an antioxidant: under promises but over delivers. J Pineal Res. 2016;61:253–278.
  • Fischer TW, Slominski A, Tobin DJ, et al. Melatonin and the hair follicle. J Pineal Res. 2008;4:1–15.
  • Fischer TW, Burmeister G, Schmidt HW, et al. Melatonin increases anagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial. Br J Dermatol. 2004;150:341–345.
  • Ramot Y, Czarnowicki T, Zlotogorski A. Finasteride induced gynecomastia: case report and review of the literature. Int J Trichology. 2009;1:27–29.
  • Leenen FH, Smith DL, Unger WP. Topical minoxidil: cardiac effects in bald man. Br J Clin Pharmacol. 1988;26:481–485.
  • Rossi A, Cantisani C, Melis L, et al. Minoxidil use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012;6:130–136.
  • Mukherjee S, Ray S, Thakur RS. Design and evaluation of itraconazole loaded solid lipid nanoparticulate system for improving the antifungal therapy. Pak J Pharm Sci. 2009;22:131–138.
  • Ranpise NS, Korabu SS, Ghodake VN. Second generation lipid nanoparticles (NLC) as an oral drug carrier for delivery of lercanidipine hydrochloride. Colloids Surf B Biointerfaces. 2014;116:81–87.
  • Agrawal Y, Petkar KC, Sawant KK. Development, evaluation and clinical studies of Acitretin loaded nanostructured lipid carriers for topical treatment of psoriasis. Int J Pharm. 2010;401:93–102.
  • Shamma RN, Aburahma MH. Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia. Int J Nanomed. 2014;9:5449–5460.
  • Fadel M, Samy N, Nasr M, et al. Topical colloidal indocyanine green-mediated photodynamic therapy for treatment of basal cell carcinoma. Pharm Dev Technol. 2017;22:545–550.
  • Abdel-Salam FS, Ammar HO, Elkheshen SA, et al. Anti-inflammatory sunscreen nanostructured lipid carrier formulations. J Drug Deliv Sci Technol. 2017;37:13–19.
  • Verma S, Doshi A. Formulation, development and characterization of nanostructured hetrolipid matrix of levofloxacin hemihydrate for ocular drug delivery. J Pharmacol Clin Toxicol. 2014;2:1–5.
  • Gonzalez-Paredes A, Clarés-Naveros B, Adolfina Ruiz-Martinez M, et al. Delivery systems for natural antioxidant compounds: archaeosomes and archaeosomal hydrogels characterization and release study. Int J Pharm. 2011;421:321–331.
  • Mishra K, Ojha H, Chaudhury NK. Estimation of antiradical properties of antioxidants using DPPH assay: a critical review and results. Food Chemistry. 2012;130:1036–1043.
  • Nasr M. Development of an optimized hyaluronic acid-based lipidic nanoemulsion co-encapsulating two polyphenols for nose to brain delivery. Drug Deliv. 2016;23:1444–1452.
  • Das S, Ng WK, Kanaujia p, et al. Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables. Colloids Surf B. 2011;88:483–489.
  • Gaba B, Fazil M, Khan S, et al. Nanostructured lipid carrier system for topical delivery of terbinafine hydrochloride. Bulletin of Faculty of Pharmacy, Cairo University. 2015;53:147–159.
  • Mohammed MM, Hamadi SA, Aljaf AN. Formulation of melatonin as a cream and studying the release, diffusion, and stability of the cream. AJPS. 2009;6:43–55.
  • Nasr M, Abdel-Hamid S. Optimizing the dermal accumulation of a tazarotene microemulsion using skin deposition. Drug Dev Ind Pharm. 2016;42:636–643.
  • Nasr M, Abdel-Hamid S, Moftah NH, et al. Jojoba oil soft colloidal nanocarrier of a synthetic retinoid: preparation, characterization and clinical efficacy in psoriatic patients. Curr Drug Deliv. 2017;14:426–432.
  • Yousry C, Fahmy RH, Essam T, et al. Nanoparticles as tool for enhanced ophthalmic delivery of vancomycin: a multidistrict-based microbiological study, solid lipid nanoparticles formulation and evaluation. Drug Dev Ind Pharm. 2016;42:1752–1762.
  • Abdel-Salam FS, Mahmoud AA, Ammar HO, et al. Nanostructured lipid carriers as semisolid topical delivery formulations for diflucortolone valerate. J Liposome Res. 2017;27:41–55.
  • Bsieso EA, Nasr M, Moftah NH, et al. Could nanovesicles containing a penetration enhancer clinically improve the therapeutic outcome in skin fungal diseases? Nanomedicine (Lond). 2015;10:2017–2031.
  • Abdallah MA, El-Zawahry KA, Besar HA. Mesotherapy using dutasteride-containing solution in male pattern hair loss: a controlled pilot study. J Pan-Arab League of Dermatologists. 2009;20:137–145.
  • Jha AK, Udayan UK, Roy PK, et al. Platelet-rich plasma with microneedling in androgenetic alopecia along with dermoscopic pre- and post-treatment evaluation. J Cosmet Dermatol. 2018;17:313–318.
  • Dhurat R, Saraogi p. Hair evaluation methods: merits and demerits. Int J Trichology. 2009;1:108–119.
  • El-Domyati M, Hosam W, Moftah NH, et al. Hair follicle changes following intense pulsed light axillary hair reduction: histometrical, histological and immunohistochemical evaluation. Arch Dermatol Res. 2017;309:191–202.
  • Al-Qushawi A, Rassouli A, Atyabi F, et al. Preparation and characterization of three tilmicosin-loaded lipid nanoparticles: physicochemical properties and in-vitro antibacterial activities. Iran J Pharm Res. 2016;15:663–676.
  • Pathak p, Nagarsenker M. Formulation and evaluation of lidocaine lipid nanosystems for dermal delivery. AAPS PharmSciTech. 2009;10:985–992.
  • Lason E, Sikora E, Ogonowsko J. Influence of process parameters on properties of nanostructured lipid carriers (NLC) formulation. Acta Biochim Pol. 2013;60:773–777.
  • Fang YP, Lin YK, Su YH, et al. Tryptanthrin-loaded nanoparticles for delivery into cultured human breast cancer cells, MCF7: the effects of solid lipid/liquid lipid ratios in the inner core. Chem Pharm Bull (Tokyo). 2011;59:266–271.
  • Khalil RM, Abd El-Bary A, Kassem MA, et al. Influence of formulation parameters on the physicochemical properties of meloxicam-loaded solid lipid nanoparticles. EJP. 2013;12:63–72.
  • Huang Z, Hua S, Yang Y, et al. Development and evaluation of lipid nanoparticles for camptothecin delivery: a comparison of solid lipid nanoparticles, nanostructured lipid carriers, and lipid emulsion. Acta Pharmacol Sin. 2008;29:1094–1102.
  • Dubey V, Mishra D, Asthana A, et al. Transdermal delivery of a pineal hormone: melatonin via elastic liposomes. Biomaterials. 2006;27:3491–3496.
  • Priano L, Esposti D, Esposti R, et al. Solid lipid nanoparticles incorporating melatonin as new model for sustained oral and transdermal delivery systems. J Nanosci Nanotechnol. 2007;7:3596–3601.
  • Sabzichi M, Samadi N, Mohammadian J, et al. Sustained release of melatonin: a novel approach in elevating efficacy of tamoxifen in breast cancer treatment. Colloids Surf B Biointerfaces. 2016;145:64–71.
  • Khames A. Preparation and characterization of sildenafil loaded solid lipid nanoparticles: drug delivery system suitable for nebulization. Der Pharmacia Lettre. 2017;9:98–112.
  • Palei NN, Das MK. Preparation and characterization of lornoxicam loaded solid lipid nanoparticles made from different lipids. Int J Pharm Pharm Sci. 2013;5:438–442.
  • Cerreto F, Paolicelli p, Cesa S, et al. Solid lipid nanoparticles as effective reservoir systems for long-term preservation of multidose formulations. AAPS PharmSciTech. 2013;14:847–853.
  • Owen RW, Giacosa A, Hull WE, et al. The antioxidant/anticancer potential of phenolic compounds isolated from olive oil. Eur J Cancer. 2000;36:1235–1247.
  • Kalogeropoulos N, Tsimidou MZ. Antioxidants in Greek virgin olive oils. Antioxidants (Basel). 2014;3:387–413.
  • Matthaus B, Ozcan MM, Juhaimi FA, et al. Effect of the harvest time on oil yield, fatty acid, tocopherol and sterol contents of developing almond and walnut kernels. J Oleo Sci. 2018;67:39–45.
  • Amarowicz R, Troszynska A, Shahidi F. Antioxidant activity of almond extract. J Food Lipids. 2005;12:344–358.
  • Schmidt Š, Niklová I, Pokorný J, et al. Antioxidant activity of evening primrose phenolics in sunflower and rapeseed oils. Eur J Lipid Technol. 2003;105:427–435.
  • Kiss AK, Derwińska M, Granica S. Quantitative analysis of biologically active polyphenols in evening primrose (Oenotheraparadoxa) seeds aqueous extracts. Pol J Food Nutr Sci. 2011;61:109–113.
  • Mujić ŠE, Jokić S, Sarić Z, et al. Isoflavone content and antioxidant properties of soybean seeds. Croat J Food Sci. 2011;3:16–20.
  • Vilaplana-Pérez C, Auñón D, García-Flores LA, et al. Hydroxytyrosol and potential uses in cardiovascular diseases, cancer, and AIDS. FrontNutr. 2014;1:1–11.
  • Das S, Ng WK, Tan RB. Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs? Eur J Pharm Sci. 2012;47:139–151.
  • Reddy LH, Murthy RSR. Etoposide-loaded nanoparticles made from glyceride lipids: formulation, characterization, in vitro drug release, and stability evaluation. AAPS PharmSciTech. 2005;6:158–166.
  • Mishra A, Imam SS, Aqil M, et al. Carvedilol nano lipid carriers: formulation, characterization and in-vivo evaluation. Drug Deliv. 2016;23:1486–1494.
  • Gokce EH, Korkmaz E, Dellera E, et al. Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications. Int J Nanomed. 2012;7:1841–1850.
  • Baroli B. Penetration of nanoparticles and nanomaterials in the skin: fiction or reality? J Pharm Sci. 2009;99:21–50.
  • Vujovic A, Del Marmol V. The female pattern hair loss: review of etiopathogenesis and diagnosis. BioMed Res Int. 2014;2014:1–8.
  • Hu R, Xu F, Han Y, et al. Trichoscopic findings of androgenetic alopecia and their association with disease severity. J Dermatol. 2015;42:602–607.
  • Kaur G, Bedi PMS, Narang JK. Targeting alopecia with topical nanocarriers. WJPPS. 2017;6:326–333.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.