Biological impact of nanodiamond particles – label free, high-resolution methods for nanotoxicity assessment

References

• Alhaddad, Anna, Marie-Pierre Adam, Jacques Botsoa, Géraldine Dantelle, Sandrine Perruchas, Thierry Gacoin, Christelle Mansuy, Solange Lavielle, Claude Malvy, François Treussart., et al. 2011. “Nanodiamond as a Vector for siRNA Delivery to Ewing Sarcoma Cells.” Small 7(21): 3087–3095. doi:10.1002/smll.201101193.
   PubMed Web of Science ®Google Scholar
• Baidakova, M. V., Y. A. Kukushkina, A. A. Sitnikova, M. A. Yagovkina, D. A. Kirilenko, V. V. Sokolov, M. S. Shestakov, A. Y. Vul’, B. Zousman, and O. Levinson. 2013. “Structure of Nanodiamonds Prepared by Laser Synthesis.” Physics of the Solid State 55(8): 1747–1753. doi:10.1134/S1063783413080027.
   Web of Science ®Google Scholar
• Berntsen, P., C. Y. Park, B. Rothen-Rutishauser, A. Tsuda, T. M. Sager, R. M. Molina, T. C. Donaghey, A. M. Alencar, D. I. Kasahara, T. Ericsson., et al. 2010. “Biomechanical Effects of Environmental and Engineered Particles on Human Airway Smooth Muscle Cells.” Journal of the Royal Society Interface 7(suppl_3), S331–S340. doi:10.1098/rsif.2010.0068.focus.[Mismatch]
   PubMedGoogle Scholar
• Bettini, Sarah, Elisa Boutet-Robinet, Christel Cartier, Christine Coméra, Eric Gaultier, Jacques Dupuy, Nathalie Naud, Sylviane Taché, Patrick Grysan, Solenn Reguer., et al. 2017. “Food-Grade TiO2 Impairs Intestinal and Systemic Immune Homeostasis, Initiates Preneoplastic Lesions and Promotes Aberrant Crypt Development in the Rat Colon.” Scientific Reports 7(1): 40373. doi:10.1038/srep40373.
   PubMedGoogle Scholar
• Boudou, J.-P., P. A. Curmi, F. Jelezko, J. Wrachtrup, P. Aubert, M. Sennour, G. Balasubramanian, R. Reuter, A. Thorel, and E. Gaffet. 2009. “High Yield Fabrication of Fluorescent Nanodiamonds.” Nanotechnology 20(23): 235602–235602. doi:10.1088/0957-4484/20/23/235602.
   PubMed Web of Science ®Google Scholar
• Brady, Mariea A., Andrea Renzing, Timothy E. L. Douglas, Qin Liu, Sebastian Wille, Martin Parizek, Lucie Bacakova, Alexander Kromka, Marketa Jarosova, Greetje Godier., et al. 2015. “Development of Composite Poly (Lactide-co-Glycolide)-Nanodiamond Scaffolds for Bone Cell Growth.” Journal of Nanoscience and Nanotechnology 15(2): 1060–1069. doi:10.1166/jnn.2015.9745.
   PubMed Web of Science ®Google Scholar
• Butt, H.-J., B. Cappella, and M. Kappl. 2005. “Force Measurements with the Atomic Force Microscope: Technique, Interpretation and Applications.” Surface Science Reports 59(1-6): 1–152. doi:10.1016/j.surfrep.2005.08.003.
   Web of Science ®Google Scholar
• Buyukhatipoglu, K., and A. M. Clyne. 2011. “Superparamagnetic Iron Oxide Nanoparticles Change Endothelial Cell Morphology and Mechanics via Reactive Oxygen Species Formation.” Journal of Biomedical Materials Research Part A 96: 186–195. doi:10.1002/jbm.a.32972.
   PubMed Web of Science ®Google Scholar
• Cai, X., X. Xing, J. Cai, Q. Chen, S. Wu, and F. Huang. 2010. “Connection between Biomechanics and Cytoskeleton Structure of Lymphocyte and Jurkat Cells: An AFM Study.” Micron 41(3): 257–262. doi:10.1016/j.micron.2009.08.011.
   PubMed Web of Science ®Google Scholar
• Cassio, D., and M. C. Weiss. 1979. “Expression of Fetal and Neonatal Hepatic Functions by Mouse Hepatoma-Rat Hepatoma Hybrids.” Somatic Cell Genetics 5(6): 719–738. doi:10.1007/BF01542637.
   PubMedGoogle Scholar
• Chao, J.-I., E. Perevedentseva, P.-H. Chung, K.-K. Liu, C.-Y. Cheng, C.-C. Chang, and C.-L. Cheng. 2007. “Nanometer-Sized Diamond Particle as a Probe for Biolabeling.” Biophysical Journal 93(6): 2199–2208. doi:10.1529/biophysj.107.108134.
   PubMed Web of Science ®Google Scholar
• Chaya, D., C. Fougère-Deschatrette, and M. C. Weiss. 1997. “Liver-Enriched Transcription Factors Uncoupled from Expression of Hepatic Functions in Hepatoma Cell Lines.” Molecular and Cellular Biology 17(11): 6311–6320. doi:10.1128/MCB.17.11.6311.
   PubMed Web of Science ®Google Scholar
• Chia, S. L., C. Y. Tay, M. I. Setyawati, and D. T. Leong. 2015. “Biomimicry 3D Gastrointestinal Spheroid Platform for the Assessment of Toxicity and Inflammatory Effects of Zinc Oxide Nanoparticles.” Small 11(6): 702–712. doi:10.1002/smll.201401915.
   PubMed Web of Science ®Google Scholar
• Chu, Z., K. Miu, P. Lung, S. Zhang, S. Zhao, H.-C. Chang, G. Lin, and Q. Li. 2015. “Rapid Endosomal Escape of Prickly Nanodiamonds: Implications for Gene Delivery.” Scientific Reports 5(1): 11661. doi:10.1038/srep11661.
   PubMedGoogle Scholar
• Cohen, J., G. Deloid, G. Pyrgiotakis, and P. Demokritou. 2013. “Interactions of Engineered Nanomaterials in Physiological Media and Implications for in Vitro Dosimetry.” Nanotoxicology 7(4): 417–431. doi:10.3109/17435390.2012.666576.
   PubMed Web of Science ®Google Scholar
• Collins, A. R., B. Annangi, L. Rubio, R. Marcos, M. Dorn, C. Merker, I. Estrela-Lopis, M. R. Cimpan, M. Ibrahim, E. Cimpan., et al. 2017. “High Throughput Toxicity Screening and Intracellular Detection of Nanomaterials.” Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 9: E 1413. doi:10.1002/wnan.1413.
   Web of Science ®Google Scholar
• Cross, S. E., Y.-S. Jin, J. Rao, and J. K. Gimzewski. 2007. “Nanomechanical Analysis of Cells from Cancer Patients.” Nature Nanotechnology 2(12): 780. doi:10.1038/nnano.2007.388.
   PubMed Web of Science ®Google Scholar
• Daquinag, A. C., G. R. Souza, and M. G. Kolonin. 2013. “Adipose Tissue Engineering in Three-Dimensional Levitation Tissue Culture System Based on Magnetic Nanoparticles.” Tissue Engineering Part C: Methods 19(5): 336–344. doi:10.1089/ten.tec.2012.0198.
   PubMed Web of Science ®Google Scholar
• Deschatrette, J., C. Fougere-Deschatrette, L. Corcos, and R. T. Schimke. 1985. “Expression of the Mouse Serum Albumin Gene Introduced into Differentiated and Dedifferentiated Rat Hepatoma Cells.” Proceedings of the National Academy of Sciences 82(3): 765–769. doi:10.1073/pnas.82.3.765.
   PubMed Web of Science ®Google Scholar
• Dong, C., M. L. Kashon, D. Lowry, J. S. Dordick, S. H. Reynolds, Y. Rojanasakul, L. M. Sargent, and C. Z. Dinu. 2013. “Exposure to Carbon Nanotubes Leads to Changes in the Cellular Biomechanics.” Advanced Healthcare Materials 2(7): 945–951. doi:10.1002/adhm.201200430.
   PubMed Web of Science ®Google Scholar
• Edmondson, R., J. J. Broglie, A. F. Adcock, and L. Yang. 2014. “Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors.”Assay and Drug Development Technologies 12(4): 207–218. doi:10.1089/adt.2014.573.
   PubMed Web of Science ®Google Scholar
• Gupta, A. K., and A. S. Curtis. 2004. “Lactoferrin and Ceruloplasmin Derivatized Superparamagnetic Iron Oxide Nanoparticles for Targeting Cell Surface Receptors.” Biomaterials 25(15): 3029–3040. doi:10.1016/j.biomaterials.2003.09.095.
   PubMed Web of Science ®Google Scholar
• Haghi, M., D. Traini, L. G. Wood, B. Oliver, P. M. Young, and W. Chrzanowski. 2015. “A ‘Soft Spot’for Drug Transport: Modulation of Cell Stiffness Using Fatty Acids and Its Impact on Drug Transport in Lung Model.” Journal of Materials Chemistry B 3(13): 2583–2589. doi:10.1039/C4TB01928H.
   Web of Science ®Google Scholar
• Hau, H.,. D. Khanal, L. Rogers, N. Suchowerska, R. Kumar, S. Sridhar, D. McKenzie, and W. Chrzanowski. 2016. “Dose Enhancement and Cytotoxicity of Gold Nanoparticles in Colon Cancer Cells When Irradiated with Kilo- and Mega-Voltage Radiation.” Bioengineering & Translational Medicine 1: 94–102. doi:10.1002/btm2.10007.
   PubMed Web of Science ®Google Scholar
• Head, B. P., H. H. Patel, and P. A. Insel. 2014. “Interaction of Membrane/Lipid Rafts with the Cytoskeleton: Impact on Signaling and Function: Membrane/Lipid Rafts, Mediators of Cytoskeletal Arrangement and Cell Signaling.” Biochimica et Biophysica Acta (Bba) - Biomembranes 1838(2): 532–545. doi:10.1016/j.bbamem.2013.07.018.
   PubMed Web of Science ®Google Scholar
• Holt, B. D., P. A. Short, A. D. Rape, Y.-l Wang, M. F. Islam, and K. N. Dahl. 2010. “Carbon Nanotubes Reorganize Actin Structures in Cells and Ex Vivo.” ACS Nano 4(8): 4872–4878. doi:10.1021/nn101151x.
   PubMed Web of Science ®Google Scholar
• Jaffar, J.,. S.-H. Yang, S. Y. Kim, H.-W. Kim, A. Faiz, W. Chrzanowski, and J. K. Burgess. 2018. “Greater Cellular Stiffness in Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis.” American Journal of Physiology-Lung Cellular and Molecular Physiology 315(1): L59–L65. doi:10.1152/ajplung.00030.2018.
   PubMed Web of Science ®Google Scholar
• Khanal, D., A. Kondyurin, H. Hau, J. C. Knowles, O. Levinson, I. Ramzan, D. Fu, C. Marcott, and W. Chrzanowski. 2016. “Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study.” Analytical Chemistry 88(15): 7530–7538. doi:10.1021/acs.analchem.6b00665.
   PubMed Web of Science ®Google Scholar
• Khanal, D., H. Hau, A. Kondyurin, D. Fu, I. Ramzan, and W. Chrzanowski. 2017. “Nanotoxicity of Nanodiamond in Two and Three Dimensional Liver Models.” International Journal of Nanotechnology 14(1/2/3/4/5/6): 133–154. doi:10.1504/IJNT.2017.082436.
   Web of Science ®Google Scholar
• Kirmizis, D., and S. Logothetidis. 2010. “Atomic Force Microscopy Probing in the Measurement of Cell Mechanics.” International Journal of Nanomedicine 5: 137–145.
   PubMed Web of Science ®Google Scholar
• Krüger, A. 2006. “Hard and Soft: Biofunctionalized Diamond.” Angewandte Chemie (International ed. in English) 45(39): 6426–6427. doi:10.1002/anie.200602509.
   PubMed Web of Science ®Google Scholar
• Lee, Dong-Keun, Theodore Kee, Zhangrui Liang, Desiree Hsiou, Darron Miya, Brian Wu, Eiji Osawa, Edward Kai-Hua Chow, Eric C. Sung, Mo K. Kang., et al. 2017. “Clinical Validation of a Nanodiamond-Embedded Thermoplastic Biomaterial.” Proceedings of the National Academy of Sciences 114(45): E9445. doi:10.1073/pnas.1711924114.
   PubMed Web of Science ®Google Scholar
• Lee, J., G. D. Lilly, R. C. Doty, P. Podsiadlo, and N. A. Kotov. 2009. “In Vitro Toxicity Testing of Nanoparticles in 3D Cell Culture.” Small (Weinheim an Der Bergstrasse, Germany) 5(10): 1213–1221. doi:10.1002/smll.200801788.
   PubMed Web of Science ®Google Scholar
• Li, J., Y. Zhu, W. Li, X. Zhang, Y. Peng, and Q. Huang. 2010. “Nanodiamonds as Intracellular Transporters of Chemotherapeutic Drug.” Biomaterials 31(32): 8410–8418. doi:10.1016/j.biomaterials.2010.07.058.
   PubMed Web of Science ®Google Scholar
• Li, M., L. Liu, N. Xi, Y. Wang, Z. Dong, X. Xiao, and W. Zhang. 2012. “Atomic Force Microscopy Imaging and Mechanical Properties Measurement of Red Blood Cells and Aggressive Cancer Cells.” Science China Life Sciences 55(11): 968–973. doi:10.1007/s11427-012-4399-3.
   PubMed Web of Science ®Google Scholar
• Liu, K.-K., C.-L. Cheng, C.-C. Chang, and J.-I. Chao. 2007. “Biocompatible and Detectable Carboxylated Nanodiamond on Human Cell.” Nanotechnology 18(32): 325102. doi:10.1088/0957-4484/18/32/325102.
   Web of Science ®Google Scholar
• Luo, X., H. Zhang, Z. Cao, N. Cai, Y. Xue, and F. Yu. 2016. “A Simple Route to Develop Transparent Doxorubicin-Loaded Nanodiamonds/Cellulose Nanocomposite Membranes as Potential Wound Dressings.” Carbohydrate Polymers 143: 231–238. doi:10.1016/j.carbpol.2016.01.076.
   PubMed Web of Science ®Google Scholar
• Manus, L. M., D. J. Mastarone, E. A. Waters, X.-Q. Zhang, E. A. Schultz-Sikma, K. W. MacRenaris, D. Ho, and T. J. Meade. 2010. “Gd (III)-Nanodiamond Conjugates for MRI Contrast Enhancement.” Nano Letters 10(2): 484–489. doi:10.1021/nl903264h.
   PubMed Web of Science ®Google Scholar
• Mochalin, V. N., O. Shenderova, D. Ho, and Y. Gogotsi. 2012. “The Properties and Applications of Nanodiamonds.” Nature Nanotechnology 7(1): 11–23. doi:10.1038/nnano.2011.209.
   Web of Science ®Google Scholar
• Moche, H., V. Paget, D. Chevalier, E. Lorge, N. Claude, H. A. Girard, J. C. Arnault, S. Chevillard, and F. Nesslany. 2017. “Carboxylated Nanodiamonds Can Be Used as Negative Reference in in Vitro Nanogenotoxicity Studies.” Journal of Applied Toxicology 37(8): 954–961. doi:10.1002/jat.3443.
   PubMed Web of Science ®Google Scholar
• Mytych, J., A. Lewinska, A. Bielak-Zmijewska, W. Grabowska, J. Zebrowski, and M. Wnuk. 2014. “Nanodiamond-Mediated Impairment of Nucleolar Activity Is Accompanied by Oxidative Stress and DNMT2 Upregulation in Human Cervical Carcinoma Cells.” Chemico-Biological Interactions 220: 51–63. doi:10.1016/j.cbi.2014.06.004.
   PubMed Web of Science ®Google Scholar
• Ong, K. J., T. J. MacCormack, R. J. Clark, J. D. Ede, V. A. Ortega, L. C. Felix, M. K. Dang, G. Ma, H. Fenniri, J. G. Veinot., et al. 2014. “Widespread Nanoparticle-Assay Interference: Implications for Nanotoxicity Testing.”PloS One 9(3): e90650. doi:10.1371/journal.pone.0090650.
   PubMed Web of Science ®Google Scholar
• Paget, V., J. A. Sergent, R. Grall, S. Altmeyer-Morel, H. A. Girard, T. Petit, C. Gesset, M. Mermoux, P. Bergonzo, J. C. Arnault., et al. 2014. “Carboxylated Nanodiamonds Are Neither Cytotoxic nor Genotoxic on Liver, Kidney, Intestine and Lung Human Cell Lines.” Nanotoxicology 8(sup1): 46–56. doi:10.3109/17435390.2013.855828.
   PubMed Web of Science ®Google Scholar
• Peng, F., M. I. Setyawati, J. K. Tee, X. Ding, J. Wang, M. E. Nga, H. K. Ho, and D. T. Leong. 2019. “Nanoparticles Promote in Vivo Breast Cancer Cell Intravasation and Extravasation by Inducing Endothelial Leakiness.” Nature Nanotechnology 14(3): 279. doi:10.1038/s41565-018-0356-z.
   PubMed Web of Science ®Google Scholar
• Peper, J. K., H. Schuster, M. W. Löffler, B. Schmid-Horch, H.-G. Rammensee, and S. Stevanović. 2014. “An Impedance-Based Cytotoxicity Assay for Real-Time and Label-Free Assessment of T-Cell-Mediated Killing of Adherent Cells.” Journal of Immunological Methods 405: 192–198. doi:10.1016/j.jim.2014.01.012.
   PubMed Web of Science ®Google Scholar
• Pinget, G., J. Tan, B. Janac, N. O. Kaakoush, A. S. Angelatos, J. O'Sullivan, Y. C. Koay, F. Sierro, J. Davis, S. K. Divakarla., et al. 2019. “Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction.” Frontiers in Nutrition 6: 57. doi:10.3389/fnut.2019.00057.
   PubMed Web of Science ®Google Scholar
• Sarhan, O. M. M., and R. M. Hussein. 2014. “Effects of Intraperitoneally Injected Silver Nanoparticles on Histological Structures and Blood Parameters in the Albino Rat.” International Journal of Nanomedicine 9: 1505–1517.
   PubMed Web of Science ®Google Scholar
• Schrand, A. M., L. Dai, J. J. Schlager, S. M. Hussain, and E. Osawa. 2007. “Differential Biocompatibility of Carbon Nanotubes and Nanodiamonds.” Diamond and Related Materials 16(12): 2118–2123. doi:10.1016/j.diamond.2007.07.020.
   Web of Science ®Google Scholar
• Setyawati, M. I., C. Y. Tay, B. H. Bay, and D. T. Leong. 2017. “Gold Nanoparticles Induced Endothelial Leakiness Depends on Particle Size and Endothelial Cell Origin.” ACS Nano 11(5): 5020–5030. doi:10.1021/acsnano.7b01744.
   PubMed Web of Science ®Google Scholar
• Setyawati, M. I., V. N. Mochalin, and D. T. Leong. 2016. “Tuning Endothelial Permeability with Functionalized Nanodiamonds.” ACS Nano 10(1): 1170–1181. doi:10.1021/acsnano.5b06487.
   PubMed Web of Science ®Google Scholar
• Setyawati, M.I., C.Y. Tay, S.L. Chia, S.L. Goh, W. Fang, M.J. Neo, H.C. Chong, S.M. Tan, S.C.J. Loo, K.W. Ng., et al. 2013. “Titanium Dioxide Nanomaterials Cause Endothelial Cell Leakiness by Disrupting the Homophilic Interaction of VE–Cadherin.” Nature Communications 4(1): 1673. doi:10.1038/ncomms2655.
   PubMedGoogle Scholar
• Solarska, K., A. Gajewska, W. Kaczorowski, G. Bartosz, and K. Mitura. 2012. “Effect of Nanodiamond Powders on the Viability and Production of Reactive Oxygen and Nitrogen Species by Human Endothelial Cells.” Diamond and Related Materials 21: 107–113. doi:10.1016/j.diamond.2011.10.020.
   Web of Science ®Google Scholar
• Subbiah, R., S. Ramasundaram, P. Du, K. Hyojin, D. Sung, K. Park, N.-E. Lee, K. Yun, and K. J. Choi. 2013. “Evaluation of Cytotoxicity, Biophysics and Biomechanics of Cells Treated with Functionalized Hybrid Nanomaterials.” Journal of the Royal Society Interface 10(88): 20130694. doi:10.1098/rsif.2013.0694.
   PubMed Web of Science ®Google Scholar
• Timm, David M., Jianbo Chen, David Sing, Jacob A. Gage, William L. Haisler, Shane K. Neeley, Robert M. Raphael, Mehdi Dehghani, Kevin P. Rosenblatt, T. C. Killian., et al. 2013. “A High-Throughput Three-Dimensional Cell Migration Assay for Toxicity Screening with Mobile Device-Based Macroscopic Image Analysis.” Scientific Reports 3(1): 1–8. doi:10.1038/srep03000.
   Google Scholar
• Tseng, Hubert, Jacob A. Gage, Tsaiwei Shen, William L. Haisler, Shane K. Neeley, Sue Shiao, Jianbo Chen, Pujan K. Desai, Angela Liao, Chris Hebel., et al. 2015. “A Spheroid Toxicity Assay Using Magnetic 3D Bioprinting and Real-Time Mobile Device-Based Imaging.” Scientific Reports 5 (1): 13987. doi:10.1038/srep13987.
   PubMedGoogle Scholar
• Wang, D., Y. Tong, Y. Li, Z. Tian, R. Cao, and B. Yang. 2013. “PEGylated Nanodiamond for Chemotherapeutic Drug Delivery.” Diamond and Related Materials 36: 26–34. doi:10.1016/j.diamond.2013.04.002.
   Web of Science ®Google Scholar
• Webb, H. K., V. K. Truong, J. Hasan, R. J. Crawford, and E. P. Ivanova. 2011. “Physico-Mechanical Characterisation of Cells Using Atomic Force Microscopy—Current Research and Methodologies.” Journal of Microbiological Methods 86 (2): 131–139. doi:10.1016/j.mimet.2011.05.021.
   PubMed Web of Science ®Google Scholar
• Wei, H., O. T. Bruns, M. G. Kaul, E. C. Hansen, M. Barch, A. Wiśniowska, O. Chen, Y. Chen, N. Li, S. Okada., et al. 2017. “Exceedingly Small Iron Oxide Nanoparticles as Positive MRI Contrast Agents.” Proceedings of the National Academy of Sciences 114(9): 2325–2330. doi:10.1073/pnas.1620145114.
   PubMed Web of Science ®Google Scholar
• Xie, F. Y., W. G. Xie, L. Gong, W. H. Zhang, S. H. Chen, Q. Z. Zhang, and J. Chen. 2010. “Surface Characterization on Graphitization of Nanodiamond Powder Annealed in Nitrogen Ambient.” Surface and Interface Analysis 42(9): 1514–1518. doi:10.1002/sia.3350.
   Web of Science ®Google Scholar
• Yamada, K. M., and E. Cukierman. 2007. “Modeling Tissue Morphogenesis and Cancer in 3D.” Cell 130(4): 601–610. doi:10.1016/j.cell.2007.08.006.
   PubMed Web of Science ®Google Scholar
• Yamashita, Kohei, Yasuo Yoshioka, Kazuma Higashisaka, Kazuya Mimura, Yuki Morishita, Masatoshi Nozaki, Tokuyuki Yoshida, Toshinobu Ogura, Hiromi Nabeshi, Kazuya Nagano., et al. 2011. “Silica and Titanium Dioxide Nanoparticles Cause Pregnancy Complications in Mice.” Nature Nanotechnology 6(5): 321. doi:10.1038/nnano.2011.41.
   PubMed Web of Science ®Google Scholar
• Yu, S.-J., M.-W. Kang, H.-C. Chang, K.-M. Chen, and Y.-C. Yu. 2005. “Bright Fluorescent Nanodiamonds: No Photobleaching and Low Cytotoxicity.” Journal of the American Chemical Society 127(50): 17604–17605. doi:10.1021/ja0567081.
   PubMed Web of Science ®Google Scholar
• Yuan, Y., Y. Chen, J.-H. Liu, H. Wang, and Y. Liu. 2009. “Biodistribution and Fate of Nanodiamonds in Vivo.” Diamond and Related Materials 18: 95–100. doi:10.1016/j.diamond.2008.10.031.
   Web of Science ®Google Scholar
• Zhang, Q., V. N. Mochalin, I. Neitzel, K. Hazeli, J. Niu, A. Kontsos, J. G. Zhou, P. I. Lelkes, and Y. Gogotsi. 2012. “Mechanical Properties and Biomineralization of Multifunctional nanodiamond-PLLA Composites for Bone Tissue Engineering.” Biomaterials 33(20): 5067–5075. doi:10.1016/j.biomaterials.2012.03.063.
   PubMed Web of Science ®Google Scholar
• Zhao, L., Y.-H. Xu, T. Akasaka, S. Abe, N. Komatsu, F. Watari, and X. Chen. 2014. “Polyglycerol-Coated Nanodiamond as a Macrophage-Evading Platform for Selective Drug Delivery in Cancer Cells.” Biomaterials 35(20): 5393–5406. doi:10.1016/j.biomaterials.2014.03.041.
   PubMed Web of Science ®Google Scholar