404
Views
11
CrossRef citations to date
0
Altmetric
Articles

Length-dependent toxicity of TiO2 nanofibers: mitigation via shortening

ORCID Icon, ORCID Icon, , , , , , , , , , , , ORCID Icon & show all
Pages 433-452 | Received 19 Apr 2019, Accepted 26 Oct 2019, Published online: 15 Nov 2019

References

  • Allegri, M., M. G. Bianchi, M. Chiu, J. Varet, A. L. Costa, S. Ortelli, et al. 2016. “Shape-Related Toxicity of Titanium Dioxide Nanofibres.” PLoS One 11(3): E 0151365. doi:10.1371/journal.pone.0151365.
  • Allegri, M., D. K. Perivoliotis, M. G. Bianchi, M. Chiu, A. Pagliaro, M. A. Koklioti, A. A. Trompeta, et al. 2016. “Toxicity Determinants of Multi-Walled Carbon Nanotubes: The Relationship between Functionalization and Agglomeration.” Toxicology Reports 3: 230–243. doi:10.1016/j.toxrep.2016.01.011.
  • Banga, A., F. A. Witzmann, H. I. Petrache, and B. L. Blazer-Yost. 2012. “Functional Effects of Nanoparticle Exposure on Calu-3 Airway Epithelial Cells.” Cellular Physiology and Biochemistry 29(1–2): 197–212. doi:10.1159/000337601.
  • Bartel, L. K., D. A. Hunter, K. B. Anderson, W. Yau, J. Wu, and W. E. Gato. 2019. “Short-Term Evaluation of Hepatic Toxicity of Titanium Dioxide Nanofiber (TDNF).” Drug and Chemical Toxicology 42(1): 35–42. doi:10.1080/01480545.2018.
  • Bianchi, M. G., M. Allegri, M. Chiu, A. L. Costa, M. Blosi, S. Ortelli, O. Bussolati, et al. 2017. “Lipopolysaccharide Adsorbed to the Bio-Corona of TiO2 Nanoparticles Powerfully Activates Selected Pro-Inflammatory Transduction Pathways.” Frontiers in Immunology 8: 866. doi:10.3389/fimmu.2017.00866.
  • Bianchi, M. G., M. Allegri, A. L. Costa, M. Blosi, D. Gardini, C. DEL Pivo, A. Prina-Mello, L. DI Cristo, O. Bussolati, and E. Bergamaschi. 2015. “Titanium Dioxide Nanoparticles Enhance Macrophage Activation by LPS through a TLR4-Dependent Intracellular Pathway.” Toxicology Research 4(2): 385–398. doi:10.1039/C4TX00193A.
  • Boehme, J. D., S. Pietkiewicz, I. Lavrik, A. Jeron, and D. Bruder. 2015. “Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease.” Lung 193: 947–953. doi:10.1007/s00408-015-9797-4.
  • Bustin, S. A. 2000. “Absolute Quantification of mRNA Using Real-Time Reverse Transcription Polymerase Chain Reaction Assays.” Journal of Molecular Endocrinology 25(2): 169–193. doi:10.1677/jme.0.0250169.
  • Davis, J. M., and A. D. Jones. 1988. “Comparisons of the Pathogenicity of Long and Short Fibres of Chrysotile Asbestos in Rats.” British Journal of Experimental Pathology 69(5): 717–737.
  • Davis, J. M., J. Addison, R. E. Bolton, K. Donaldson, A. D. Jones, and T. Smith. 1986. “The Pathogenicity of Long versus Short Fibre Samples of Amosite Asbestos Administered to Rats by Inhalation and Intraperitoneal Injection.” British Journal of Experimental Pathology 67(3): 415–430.
  • Davis, J. M., J. Addison, C. Mcintosh, B. G. Miller, and K. Niven. 1991. “Variations in the Carcinogenicity of Tremolite Dust Samples of Differing Morphology.” Annals of the New York Academy of Sciences 643: 473–490. doi:10.1111/j.1749-6632.1991.tb24497.x.
  • Di Cristo, L., D. Movia, M. G. Bianchi, M. Allegri, B. M. Mohamed, A. P. Bell, C. Moore, S. Pinelli, K. Rasmussen, J. Riego-Sintes, et al. 2016. “Proinflammatory Effects of Pyrogenic and Precipitated Amorphous Silica Nanoparticles in Innate Immunity Cells.” Toxicological Sciences 150(1): 40–53. doi:10.1093/toxsci/kfv258.
  • Donaldson, K., and C. A. Poland. 2013. “Nanotoxicity: Challenging the Myth of Nano-Specific Toxicity.” Current Opinion in Biotechnology 24(4): 724–734. doi:10.1016/j.copbio.2013.05.003.
  • Donaldson, K., and C. L. Tran. 2004. “An Introduction to the Short-Term Toxicology of Respirable Industrial Fibres.” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 553(1–2): 5–9. doi:10.1016/j.mrfmmm.2004.06.011.
  • Donaldson, K., G. M. Brown, D. M. Brown, R. E. Bolton, and J. M. Davis. 1989. “Inflammation Generating Potential of Long and Short Fibre Amosite Asbestos Samples.” Occupational and Environmental Medicine 46: 271–276. doi:10.1136/oem.46.4.271.
  • Donaldson, K., F. Murphy, A. Schinwald, R. Duffin, and C. A. Poland. 2011. “Identifying the Pulmonary Hazard of High Aspect Ratio Nanoparticles to Enable Their Safety-by-Design.” Nanomedicine 6(1): 143–156. doi:10.2217/nnm.10.139.
  • Donaldson, K., A. Schinwald, F. Murphy, W. S. Cho, R. Duffin, L. Tran, and C. Poland. 2013. “The Biologically Effective Dose in Inhalation Nanotoxicology.” Accounts of Chemical Research 46(3): 723–732. doi:10.1021/ar300092y.
  • Esch, R. K., L. Han, K. K. Foarde, and D. S. Ensor. 2010. “Endotoxin Contamination of Engineered Nanomaterials.” Nanotoxicology 4(1): 73–83. doi:10.3109/17435390903428851.
  • Farcal, L., F. Torres Andon, L. DI Cristo, B. M. Rotoli, O. Bussolati, E. Bergamaschi, A. Mech, et al. 2015. “Comprehensive in Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy.” PLoS One 10(5): e0127174. doi:10.1371/journal.pone.0127174.
  • Gato, W. E., D. A. Hunter, I. C. Byrd, C. A. Mays, W. Yau, and J. Wu. 2017. “Assessment of the Short-Term Toxicity of TiO2 Nanofiber in Sprague Dawley Rats.” Environmental Toxicology 32(6): 1775–1783. doi:10.1002/tox.22400.
  • Goodglick, L. A., and A. B. Kane. 1990. “Cytotoxicity of Long and Short Crocidolite Asbestos Fibers in Vitro and in Vivo.” Cancer Research 50(16): 5153–5163.
  • Hamilton, R. F., N. Q. Wu, C. C. Xiang, M. Li, F. Yang, M. Wolfarth, D. W. Porter, and A. Holian. 2014. “Synthesis, Characterization, and Bioactivity of Carboxylic Acid-Functionalized Titanium Dioxide Nanobelts.” Particle and Fibre Toxicology 11(1): 43. doi:10.1186/s12989-014-0043-7.
  • Hamilton, R. F., N. Wu, D. Porter, M. Buford, M. Wolfarth, and A. Holian. 2009. “Particle Length-Dependent Titanium Dioxide Nanomaterials Toxicity and Bioactivity.” Particle and Fibre Toxicology 6(1): 35. doi:10.1186/1743-8977-6-35.
  • Hunter, D. A., L. K. Bartel, I. Byrd, B. Bogan, W. Yau, J. Wu, and W. E. Gato. 2018. “Short-Term Effects of Titanium Dioxide Nanofiber on the Renal Function of Male Sprague Dawley Rats.” Journal of Environmental Pathology, Toxicology and Oncology 37(2): 127–138. doi:10.1615/JEnvironPatholToxicolOncol.2018025351.
  • Jessop, F., R. F. Jr. Hamilton, J. F. Rhoderick, P. Fletcher, A. Holian. and 2017. “Phagolysosome Acidification Is Required for Silica and Engineered Nanoparticle-Induced Lysosome Membrane Permeabilization and Resultant NLRP3 Inflammasome Activity.” Toxicology and Applied Pharmacology 318: 58–68. doi:10.1016/j.taap.2017.01.012.
  • Ji, Z., X. Wang, H. Zhang, S. Lin, H. Meng, B. Sun, S. George, T. Xia, A. E. Nel, and J. I. Zink. 2012. “Designed Synthesis of CeO2 Nanorods and Nanowires for Studying Toxicological Effects of High Aspect Ratio Nanomaterials.” ACS Nano 6(6): 5366–5380. doi:10.1021/nn3012114.
  • Kuschner, M., and G. Wright. 1976. "The effects of intratracheal instillation of glass fiber of varying sizes in guinea pigs." In Occupational Exposure to Fibrous Glass: Proceedings of a Symposium HEW (NIOSH), 151-168. Washington, DC: U.S. Government Printing Office.
  • Mills, C. D., K. Kincaid, J. M. Alt, M. J. Heilman, and A. M. Hill. 2000. “M-1/M-2 Macrophages and the Th1/Th2 Paradigm.” The Journal of Immunology 164(12): 6166–6173. doi:10.4049/jimmunol.164.12.6166.
  • Murphy, F. A., C. A. Poland, R. Duffin, K. T. Al-Jamal, H. Ali-Boucetta, A. Nunes, F. Byrne, A. Prina-Mello, Y. Volkov, S Li, S. J. Mather, et al. 2011. “Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura.” The American Journal of Pathology 178(6): 2587–2600. doi:10.1016/j.ajpath.2011.02.040.
  • Murray, P. J., J. E. Allen, S. K. Biswas, E. A. Fisher, D. W. Gilroy, S. Goerdt, S. Gordon, J. A. Hamilton, L. B. Ivashkiv, T. Lawrence., et al. 2014. “Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines.” Immunity 41(1): 14–20. doi:10.1016/j.immuni.2014.06.008.
  • NIOSH. 2013. “Occupational Exposure to Carbon Nanotubes and Nanofibers.” https://www.cdc.gov/niosh/docs/2013-145/pdfs/2013-145.pdf
  • O'Brien, J., I. Wilson, T. Orton, and F. Pognan. 2000. “Investigation of the Alamar Blue (Resazurin) Fluorescent Dye for the Assessment of Mammalian Cell Cytotoxicity.” European Journal of Biochemistry 267(17): 5421–5426. doi:10.1046/j.1432-1327.2000.01606.x.
  • Poland, C. A., R. Duffin, I. Kinloch, A. Maynard, W. A. Wallace, A. Seaton, V. Stone, S. Brown, W. Macnee, and K. Donaldson. 2008. “Carbon Nanotubes Introduced into the Abdominal Cavity of Mice Show Asbestos-like Pathogenicity in a Pilot Study.” Nature Nanotechnology 3(7): 423–428. doi:10.1038/nnano.2008.111.
  • Poland, C. A., F. Byrne, W.-S. Cho, A. Prina-Mello, F. A. Murphy, G. L. Davies, J. M. D. Coey, et al. 2012. “Length-Dependent Pathogenic Effects of Nickel Nanowires in the Lungs and the Peritoneal Cavity.” Nanotoxicology 6(8): 899–911. doi:10.3109/17435390.2011.626535.
  • Polimeni, M., G. R. Gulino, E. Gazzano, J. Kopecka, A. Marucco, I. Fenoglio, F. Cesano, et al. 2015. “Multi-Walled Carbon Nanotubes Directly Induce Epithelial-Mesenchymal Transition in Human Bronchial Epithelial Cells via the TGF-Beta-Mediated Akt/GSK-3beta/SNAIL-1 Signalling Pathway.” Particle and Fibre Toxicology 13(1): 27. doi:10.1186/s12989-016-0138-4.
  • Porter, D. W., N. Wu, A. F. Hubbs, R. R. Mercer, K. Funk, F. Meng, J. Li, et al. 2013. “Differential Mouse Pulmonary Dose and Time Course Responses to Titanium Dioxide Nanospheres and Nanobelts.” Toxicological Sciences 131(1): 179–193. doi:10.1093/toxsci/kfs261.
  • Rotoli, B. M., O. Bussolati, A. Barilli, P. P. Zanello, M. G. Bianchi, A. Magrini, A. Pietroiusti, A. Bergamaschi, and E. Bergamaschi. 2009. “Airway Barrier Dysfunction Induced by Exposure to Carbon Nanotubes in Vitro: Which Role for Fiber Length?” Human & Experimental Toxicology 28(6-7): 361–368. doi:10.1177/0960327109105159.
  • Rotoli, B. M., O. Bussolati, M. G. Bianchi, A. Barilli, C. Balasubramanian, S. Bellucci, and E. Bergamaschi. 2008. “Non-Functionalized Multi-Walled Carbon Nanotubes Alter the Paracellular Permeability of Human Airway Epithelial Cells.” Toxicology Letters 178(2): 95–102. doi:10.1016/j.toxlet.2008.02.007.
  • Rotoli, B. M., R. Gatti, D. Movia, M. G. Bianchi, L. Di Cristo, I. Fenoglio, F. Sonvico, E. Bergamaschi, A. Prina-Mello, and O. Bussolati. 2015. “Identifying Contact-Mediated, Localized Toxic Effects of MWCNT Aggregates on Epithelial Monolayers: A Single-Cell Monitoring Toxicity Assay.” Nanotoxicology 9(2): 230–241. doi:10.3109/17435390.2014.918203.
  • Salem, L. B., C. Bosquillon, L. A. Dailey, L. Delattre, G. P. Martin, B. Evrard, and B. Forbes. 2009. “Sparing Methylation of Beta-Cyclodextrin Mitigates Cytotoxicity and Permeability Induction in Respiratory Epithelial Cell Layers in Vitro.” Journal of Controlled Release 136(2): 110–116. doi:10.1016/j.jconrel.2009.01.019.
  • Schinwald, A., T. Chernova, and K. Donaldson. 2012a. “Use of Silver Nanowires to Determine Thresholds for Fibre Length-Dependent Pulmonary Inflammation and Inhibition of Macrophage Migration in Vitro.” Particle and Fibre Toxicology 9(1): 47. doi:10.1186/1743-8977-9-47.
  • Schinwald, A., F. A. Murphy, A. Prina-Mello, C. A. Poland, F. Byrne, D. Movia, J. R. Glass, et al. 2012b. “The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma.” Toxicological Sciences 128(2): 461–470. doi:10.1093/toxsci/kfs171.
  • Smulders, S., J. P. Kaiser, S. Zuin, K. L. Van Landuyt, L. Golanski, J. Vanoirbeek, P. Wick, and P. H. Hoet. 2012. “Contamination of Nanoparticles by Endotoxin: Evaluation of Different Test Methods.” Particle and Fibre Toxicology 9: 41. doi:10.1186/1743-8977-9-41.
  • Stanton, M. F., M. Layard, A. Tegeris, E. Miller, M. May, and E. Kent. 1977. “Carcinogenicity of Fibrous Glass: Pleural Response in the Rat in Relation to Fiber Dimension.” JNCI: Journal of the National Cancer Institute 58(3): 587–603. doi:10.1093/jnci/58.3.587.
  • Sweeney, S., D. Grandolfo, P. Ruenraroengsak, and T. D. Tetley. 2015. “Functional Consequences for Primary Human Alveolar Macrophages following Treatment with Long, but Not Short, Multiwalled Carbon Nanotubes.” International Journal of Nanomedicine 10: 3115–3129. doi:10.2147/IJN.S77867.
  • Tilton, S. C., N. J. Karin, A. Tolic, Y. Xie, X. Lai, R. F. Jr Hamilton, K. M. Waters, A. Holian, F. A. Witzmann, and G. Orr. 2014. “Three Human Cell Types Respond to Multi-Walled Carbon Nanotubes and Titanium Dioxide Nanobelts with Cell-Specific Transcriptomic and Proteomic Expression Patterns.” Nanotoxicology 8(5): 533–548. doi:10.3109/17435390.2013.803624.
  • WHO. 1997. Determination of Airborne Fibre Number Concentrations. A Recommended Method, by Phase-Contrast Optical Microscopy Membrane Filter Method. Geneva, Switzerland: World Health Organization.
  • Xia, T., R. F. Hamilton, J. C. Bonner, E. D. Crandall, A. Elder, F. Fazlollahi, T. A. Girtsman, et al. 2013. “Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium.” Environmental Health Perspectives 121(6): 683–690. doi:10.1289/ehp.1306561.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.