Exposure to carbon black nanoparticles increases seizure susceptibility in male mice

References

• Arrieta, O., G. Palencia, G. Garcia-Arenas, D. Morales-Espinosa, N. Hernandez-Pedro, and J. Sotelo. 2005. “Prolonged Exposure to Lead Lowers the Threshold of Pentylenetetrazole-Induced Seizures in Rats.” Epilepsia 46 (10): 1599–1602. doi:10.1111/j.1528-1167.2005.00267.x.
   PubMed Web of Science ®Google Scholar
• Avoli, M., C. Drapeau, J. Louvel, R. Pumain, A. Olivier, and J. G. Villemure. 1991. “Epileptiform Activity Induced by Low Extracellular Magnesium in the Human Cortex Maintained In Vitro.” Annals of Neurology 30 (4): 589–596. doi:10.1002/ana.410300412.
   PubMed Web of Science ®Google Scholar
• Boland, S., S. Hussain, and A. Baeza-Squiban. 2014. “Carbon Black and Titanium Dioxide Nanoparticles Induce Distinct Molecular Mechanisms of Toxicity.” Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 6 (6): 641–652. doi:10.1002/wnan.1302.
   PubMed Web of Science ®Google Scholar
• Brevard, M. E., P. Kulkarni, J. A. King, and C. F. Ferris. 2006. “Imaging the Neural Substrates Involved in the Genesis of Pentylenetetrazol-Induced Seizures.” Epilepsia 47 (4): 745–754. doi:10.1111/j.1528-1167.2006.00502.x.
   PubMed Web of Science ®Google Scholar
• Cakmak, S., R. E. Dales, and C. B. Vidal. 2010. “Air Pollution and Hospitalization for Epilepsy in Chile.” Environment International 36 (6): 501–505. doi:10.1016/j.envint.2010.03.008.
   PubMed Web of Science ®Google Scholar
• Delorenzo, R. J., S. Pal, and S. Sombati. 1998. “Prolonged Activation of the N-Methyl-D-aspartate receptor-Ca2+ Transduction Pathway Causes Spontaneous Recurrent Epileptiform Discharges in Hippocampal Neurons in Culture.” Proceedings of the National Academy of Sciences 95 (24): 14482–14487. doi:10.1073/pnas.95.24.14482.
   PubMed Web of Science ®Google Scholar
• Devinsky, O., A. Vezzani, S. Najjar, N. C. De Lanerolle, and M. A. Rogawski. 2013. “Glia and Epilepsy: Excitability and Inflammation.” Trends in Neurosciences. 36 (3): 174–184. doi:10.1016/j.tins.2012.11.008.
   PubMed Web of Science ®Google Scholar
• Dhir, A., P. S. Naidu, and S. K. Kulkarni. 2007. “Neuroprotective Effect of Nimesulide, a Preferential COX-2 Inhibitor, Against Pentylenetetrazol (PTZ)-Induced Chemical Kindling and Associated Biochemical Parameters in Mice.” Seizure 16 (8): 691–697. doi:10.1016/j.seizure.2007.05.016.
   PubMed Web of Science ®Google Scholar
• El-Sayed, Y. S., R. Shimizu, A. Onoda, K. Takeda, and M. Umezawa. 2015. “Carbon Black Nanoparticle Exposure During Middle and Late Fetal Development Induces Immune Activation in Male Offspring Mice.” Toxicology 327: 53–61. doi:10.1016/j.tox.2014.11.005.
   PubMed Web of Science ®Google Scholar
• Ferraro, T. N., G. T. Golden, G. G. Smith, P. St Jean, N. J. Schork, N. Mulholland, C. Ballas, J. Schill, R. J. Buono, and W. H. Berrettini. 1999. “Mapping Loci for Pentylenetetrazol-Induced Seizure Susceptibility in Mice.” The Journal of Neuroscience 19 (16): 6733–6739. doi:10.1523/JNEUROSCI.19-16-06733.1999.
   PubMed Web of Science ®Google Scholar
• Getova, D., W. Froestl, and N. G. Bowery. 1998. “Effects of GABAB Receptor Antagonism on the Development of Pentylenetetrazol-Induced Kindling in Mice.” Brain Research 809 (2): 182–188. doi:10.1016/S0006-8993(98)00864-6.
   PubMed Web of Science ®Google Scholar
• Gramowski, A., J. Flossdorf, K. Bhattacharya, L. Jonas, M. Lantow, Q. Rahman, D. Schiffmann, D. G. Weiss, and E. Dopp. 2010. “Nanoparticles Induce Changes of the Electrical Activity of Neuronal Networks on Microelectrode Array Neurochips.” Environmental Health Perspectives 118 (10): 1363–1369. doi:10.1289/ehp.0901661.
   PubMed Web of Science ®Google Scholar
• Hjortebjerg, D., A. M. Nybo Andersen, M. Ketzel, O. Raaschou-Nielsen, and M. Sorensen. 2018. “Exposure to Traffic Noise and Air Pollution and Risk for Febrile Seizure: A Cohort Study.” Scandinavian Journal of Work, Environment & Health 44 (5): 539–546. doi:10.5271/sjweh.3724.
   PubMed Web of Science ®Google Scholar
• Huang, L., T. Yuan, M. Tan, Y. Xi, Y. Hu, Q. Tao, Z. Zhao, et al. 2017. “A Retinoraphe Projection Regulates Serotonergic Activity and Looming-Evoked Defensive Behaviour.” Nature Communications 8 (1): 14908. doi:10.1038/ncomms14908.
   PubMedGoogle Scholar
• Jackson, P., K. S. Hougaard, A. M. Boisen, N. R. Jacobsen, K. A. Jensen, P. Moller, G. Brunborg, et al. 2012. “Pulmonary Exposure to Carbon Black by Inhalation or Instillation in Pregnant Mice: Effects on Liver DNA Strand Breaks in Dams and Offspring.” Nanotoxicology 6 (5): 486–500. doi:10.3109/17435390.2011.587902.
   PubMed Web of Science ®Google Scholar
• Jackson, P., U. Vogel, H. Wallin, and K. S. Hougaard. 2011. “Prenatal Exposure to Carbon Black (Printex 90): Effects on Sexual Development and Neurofunction.” Basic & Clinical Pharmacology & Toxicology 109 (6): 434–437. doi:10.1111/j.1742-7843.2011.00745.x.
   PubMed Web of Science ®Google Scholar
• Jimenez-Mateos, E. M., T. Engel, P. Merino-Serrais, R. C. Mckiernan, K. Tanaka, G. Mouri, T. Sano, et al. 2012. “Silencing microRNA-134 Produces Neuroprotective and Prolonged Seizure-Suppressive Effects.” Nature Medicine 18 (7): 1087–1094. doi:10.1038/nm.2834.
   PubMed Web of Science ®Google Scholar
• Larner, S. F., J. Wang, J. Goodman, M. B. O. Altman, M. Xin, and K. K. W. Wang. 2017. “In Vitro Neurotoxicity Resulting from Exposure of Cultured Neural Cells to Several Types of Nanoparticles.” Journal of Cell Death 10: 1179670717694523. doi:10.1177/1179670717694523.
   Google Scholar
• Li, L. Y., J. L. Li, H. M. Zhang, W. M. Yang, K. Wang, Y. Fang, and Y. Wang. 2013. “TGFbeta1 Treatment Reduces Hippocampal Damage, Spontaneous Recurrent Seizures, and Learning Memory Deficits in Pilocarpine-Treated Rats.” Journal of Molecular Neuroscience 50 (1): 109–123. doi:10.1007/s12031-012-9879-1.
   PubMed Web of Science ®Google Scholar
• Lindner, K., M. Strobele, S. Schlick, S. Webering, A. Jenckel, J. Kopf, O. Danov, et al. 2017. “Biological Effects of Carbon Black Nanoparticles Are Changed by Surface Coating with Polycyclic Aromatic Hydrocarbons.” Particle and Fibre Toxicology 14 (1): 8. doi:10.1186/s12989-017-0189-1.
   PubMedGoogle Scholar
• Ma, J., A. Guo, S. Wang, S. Man, Y. Zhang, S. Liu, and Y. Liu. 2018. “From the Lung to the Knee Joint: Toxicity Evaluation of Carbon Black Nanoparticles on Macrophages and Chondrocytes.” Journal of Hazardous Materials 353: 329–339. doi:10.1016/j.jhazmat.2018.04.025.
   PubMed Web of Science ®Google Scholar
• Nel, A., T. Xia, L. Madler, and N. Li. 2006. “Toxic Potential of Materials at the Nanolevel.” Science 311 (5761): 622–627. doi:10.1126/science.1114397.
   PubMed Web of Science ®Google Scholar
• Oberdorster, G., A. Elder, and A. Rinderknecht. 2009. “Nanoparticles and the Brain: Cause for Concern?” Journal of Nanoscience and Nanotechnology 9: 4996–5007. doi:10.1166/jnn.2009.GR02.
   PubMed Web of Science ®Google Scholar
• Onoda, A., K. Takeda, and M. Umezawa. 2017a. “Dose-Dependent Induction of Astrocyte Activation and Reactive Astrogliosis in Mouse Brain following Maternal Exposure to Carbon Black Nanoparticle.” Particle and Fibre Toxicology 14 (1): 4. doi:10.1186/s12989-017-0184-6.
   PubMedGoogle Scholar
• Onoda, A., K. Takeda, and M. Umezawa. 2017b. “Pretreatment with N-Acetyl Cysteine Suppresses Chronic Reactive Astrogliosis Following Maternal Nanoparticle Exposure During Gestational Period.” Nanotoxicology 11 (8): 1012–1025. doi:10.1080/17435390.2017.1388864.
   PubMed Web of Science ®Google Scholar
• Onoda, A., M. Umezawa, K. Takeda, T. Ihara, and M. Sugamata. 2014. “Effects of Maternal Exposure to Ultrafine Carbon Black on Brain Perivascular Macrophages and Surrounding Astrocytes in Offspring Mice.” PLoS One. 9 (4): e94336. doi:10.1371/journal.pone.0094336.
   PubMed Web of Science ®Google Scholar
• Onoda, A., T. Kawasaki, K. Tsukiyama, K. Takeda, and M. Umezawa. 2017. “Perivascular Accumulation of β-Sheet-Rich Proteins in Offspring Brain following Maternal Exposure to Carbon Black Nanoparticles.” Frontiers in Cellular Neuroscience 11: 92. doi:10.3389/fncel.2017.00092.
   PubMed Web of Science ®Google Scholar
• Osborn, K. E., R. D. Shytle, A. T. Frontera, J. R. Soble, and M. R. Schoenberg. 2016. “Addressing Potential Role of Magnesium Dyshomeostasis to Improve Treatment Efficacy for Epilepsy: A Reexamination of the Literature.” Journal of Clinical Pharmacology. 56 (3): 260–265. doi:10.1002/jcph.626.
   PubMed Web of Science ®Google Scholar
• Paul, D., A. Dixit, A. Srivastava, M. Tripathi, D. Prakash, C. Sarkar, B. Ramanujam, J. Banerjee, and P. S. Chandra. 2018. “Altered Transforming Growth Factor Beta/SMAD3 Signalling in Patients with Hippocampal Sclerosis.” Epilepsy Research 146: 144–150. doi:10.1016/j.eplepsyres.2018.08.004.
   PubMed Web of Science ®Google Scholar
• Racine, R. J. 1972. “Modification of Seizure Activity by Electrical Stimulation. II. Motor Seizure.” Electroencephalography and Clinical Neurophysiology. 32 (3): 281–294. doi:10.1016/0013-4694(72)90177-0.
   PubMedGoogle Scholar
• Riazi, K., M. A. Galic, J. B. Kuzmiski, W. Ho, K. A. Sharkey, and Q. J. Pittman. 2008. “Microglial Activation and TNFalpha Production Mediate Altered CNS Excitability Following Peripheral Inflammation.” Proceedings of the National Academy of Sciences 105 (44): 17151–17156. doi:10.1073/pnas.0806682105.
   PubMed Web of Science ®Google Scholar
• Sada, N., S. Lee, T. Katsu, T. Otsuki, and T. Inoue. 2015. “Epilepsy Treatment. Targeting LDH Enzymes with a Stiripentol Analog to Treat Epilepsy.” Science 347 (6228): 1362–1367. doi:10.1126/science.aaa1299.
   PubMed Web of Science ®Google Scholar
• Sager, T. M., and V. Castranova. 2009. “Surface Area of Particle Administered Versus Mass in Determining the Pulmonary Toxicity of Ultrafine and Fine Carbon Black: Comparison to Ultrafine Titanium Dioxide.” Particle and Fibre Toxicology 6 (1): 15. doi:10.1186/1743-8977-6-15.
   PubMedGoogle Scholar
• Skovmand, A., A. C. O. Jensen, C. Maurice, F. Marchetti, A. J. Lauvas, I. K. Koponen, K. A. Jensen, S. Goericke-Pesch, U. Vogel, and K. S. Hougaard. 2019. “Effects of Maternal Inhalation of Carbon Black Nanoparticles on Reproductive and Fertility Parameters in a Four-Generation Study of Male Mice.” Particle and Fibre Toxicology 16 (1): 13. doi:10.1186/s12989-019-0295-3.
   PubMedGoogle Scholar
• Stampfl, A., M. Maier, R. Radykewicz, P. Reitmeir, M. Gottlicher, and R. Niessner. 2011. “Langendorff Heart: A Model System to Study Cardiovascular Effects of Engineered Nanoparticles.” ACS Nano 5 (7): 5345–5353. doi:10.1021/nn200801c.
   PubMed Web of Science ®Google Scholar
• Stienen, M. N., A. Haghikia, H. Dambach, J. Thone, M. Wiemann, R. Gold, A. Chan, et al. 2011. “Anti-Inflammatory Effects of the Anticonvulsant Drug Levetiracetam on Electrophysiological Properties of Astroglia Are Mediated via TGFbeta1 Regulation.” British Journal of Pharmacology 162 (2): 491–507. doi:10.1111/j.1476-5381.2010.01038.x.
   PubMed Web of Science ®Google Scholar
• Takeda, K., Y. Shinkai, K. Suzuki, S. Yanagita, M. Umezawa, S. Yokota, H. Tainaka, S. Oshio, T. Ihara, and M. Sugamata. 2011. “Health Effects of Nanomaterials on Next Generation.” Yakugaku Zasshi 131 (2): 229–236. doi:10.1248/yakushi.131.229.
   PubMed Web of Science ®Google Scholar
• Tin Tin Win, S., D. Mitsushima, S. Yamamoto, A. Fukushima, T. Funabashi, T. Kobayashi, and H. Fujimaki. 2008. “Changes in Neurotransmitter Levels and Proinflammatory Cytokine mRNA Expressions in the Mice Olfactory Bulb Following Nanoparticle Exposure.” Toxicology and Applied Pharmacology 226: 192–198. doi:10.1016/j.taap.2007.09.009.
   PubMed Web of Science ®Google Scholar
• Umezawa, M., A. Onoda, I. Korshunova, A. C. O. Jensen, I. K. Koponen, K. A. Jensen, K. Khodosevich, U. Vogel, and K. S. Hougaard. 2018. “Maternal Inhalation of Carbon Black Nanoparticles Induces Neurodevelopmental Changes in Mouse Offspring.” Particle and Fibre Toxicology 15 (1): 36. doi:10.1186/s12989-018-0272-2.
   PubMedGoogle Scholar
• Umezawa, M., S. Kudo, S. Yanagita, Y. Shinkai, R. Niki, T. Oyabu, K. Takeda, T. Ihara, and M. Sugamata. 2011. “Maternal Exposure to Carbon Black Nanoparticle Increases Collagen Type VIII Expression in the Kidney of Offspring.” The Journal of Toxicological Sciences 36 (4): 461–468. doi:10.2131/jts.36.461.
   PubMed Web of Science ®Google Scholar
• Vezzani, A., R. S. Fujinami, H. S. White, P. M. Preux, I. Blumcke, J. W. Sander, and W. Loscher. 2016. “Infections, Inflammation and Epilepsy.” Acta Neuropathologica 131 (2): 211–234. doi:10.1007/s00401-015-1481-5.
   PubMed Web of Science ®Google Scholar
• Voss, L. J., G. Jacobson, J. W. Sleigh, A. Steyn-Ross, and M. Steyn-Ross. 2009. “Excitatory Effects of Gap Junction Blockers on Cerebral Cortex Seizure-Like Activity in Rats and Mice.” Epilepsia 50 (8): 1971–1978. doi:10.1111/j.1528-1167.2009.02087.x.
   PubMed Web of Science ®Google Scholar
• Walz, R., O. B. Amaral, I. C. Rockenbach, R. Roesler, I. Izquierdo, E. A. Cavalheiro, V. R. Martins, and R. R. Brentani. 1999. “Increased Sensitivity to Seizures in Mice Lacking Cellular Prion Protein.” Epilepsia 40 (12): 1679–1682. doi:10.1111/j.1528-1157.1999.tb01583.x.
   PubMed Web of Science ®Google Scholar
• Whalley, B. J., G. J. Stephens, and A. Constanti. 2009. “Investigation of the Effects of the Novel Anticonvulsant Compound Carisbamate (RWJ-333369) on Rat Piriform Cortical Neurones In Vitro.” British Journal of Pharmacology 156 (6): 994–1008. doi:10.1111/j.1476-5381.2008.00110.x.
   PubMed Web of Science ®Google Scholar
• Wilczynski, G. M., F. A. Konopacki, E. Wilczek, Z. Lasiecka, A. Gorlewicz, P. Michaluk, M. Wawrzyniak, et al. 2008. “Important Role of Matrix Metalloproteinase 9 in Epileptogenesis.” The Journal of Cell Biology 180 (5): 1021–1035. doi:10.1083/jcb.200708213.
   PubMed Web of Science ®Google Scholar
• Win-Shwe, T. T., and H. Fujimaki. 2011. “Nanoparticles and Neurotoxicity.” International Journal of Molecular Sciences 12 (9): 6267–6280. doi:10.3390/ijms12096267.
   PubMed Web of Science ®Google Scholar
• Xia, T., M. Kovochich, J. Brant, M. Hotze, J. Sempf, T. Oberley, C. Sioutas, J. I. Yeh, M. R. Wiesner, and A. E. Nel. 2006. “Comparison of the Abilities of Ambient and Manufactured Nanoparticles to Induce Cellular Toxicity according to an Oxidative Stress Paradigm.” Nano Letters 6 (8): 1794–1807. doi:10.1021/nl061025k.
   PubMed Web of Science ®Google Scholar
• Xu, C., Y. N. Fan, H. D. Kan, R. J. Chen, J. H. Liu, Y. F. Li, Y. Zhang, A. L. Ji, and T. J. Cai. 2016. “The Novel Relationship Between Urban Air Pollution and Epilepsy: A Time Series Study.” PLoS One 11 (8): e0161992. doi:10.1371/journal.pone.0161992.
   PubMed Web of Science ®Google Scholar
• Yang, J., X. Zhang, Y. Wu, B. Zhao, X. Liu, Y. Pan, Y. Liu, et al. 2016. “Wnt/Beta-Catenin Signaling Mediates the Seizure-Facilitating Effect of Postischemic Reactive Astrocytes after Pentylenetetrazole-Kindling.” Glia 64: 1083–1091. doi:10.1002/glia.22984.
   PubMed Web of Science ®Google Scholar
• Yang, Y., X. Tian, D. Xu, F. Zheng, X. Lu, Y. Zhang, Y. Ma, et al. 2018. “GPR40 Modulates Epileptic Seizure and NMDA Receptor Function.” Science Advances 4 (10): eaau2357. doi:10.1126/sciadv.aau2357.
   PubMed Web of Science ®Google Scholar
• Yu, W., Y. Zou, Y. Du, J. Luo, M. Zhang, W. Yang, X. Wang, and Y. Lu. 2014. “Altered Cerebrospinal Fluid Concentrations of TGFbeta1 in Patients with Drug-Resistant Epilepsy.” Neurochemical Research 39 (11): 2211–2217. doi:10.1007/s11064-014-1422-z.
   PubMed Web of Science ®Google Scholar
• Yu, X., F. Hong, and Y. Q. Zhang. 2016. “Bio-Effect of Nanoparticles in the Cardiovascular System.” Journal of Biomedical Materials Research Part A 104 (11): 2881–2897. doi:10.1002/jbm.a.35804.
   PubMed Web of Science ®Google Scholar
• Zhang, Y., B. Tu, X. Jiang, G. Xu, X. Liu, Q. Tang, L. Bai, et al. 2019. “Exposure to Carbon Black Nanoparticles during Pregnancy Persistently Damages the Cerebrovascular Function in Female Mice.” Toxicology 422: 44–52. doi:10.1016/j.tox.2019.04.014.
   PubMed Web of Science ®Google Scholar