Practical approach to the treatment of NSAID hypersensitivity

References

• Cornejo-Garcia JA, Blanca-Lopez N, Doña I, et al. Hypersensitivity reactions to non-steroidal anti-inflammatory drugs. Current Drug Metab. 2009;10:971–980.
   PubMed Web of Science ®Google Scholar
• Torres MJ, Barrionuevo E, Kowalski M, et al. Hypersensitivity reactions to non steroidal antiiflammatory drugs. Immunol Allergy Clin North Am. 2014;34:507–524.
   PubMed Web of Science ®Google Scholar
• Kogan MD, Pappas G, Yu SM, et al. Over-the–counter medication use among US preschool-age children. Jama. 1994;272:1025–1030.
   PubMed Web of Science ®Google Scholar
• Bottoni A, Criscuolo D. Cutaneous adverse reactions following the administration of nonsteroidal antiinflammatory drugs and antibiotics: an Italian survey. Int J Clin Pharmacol Ther Toxicol. 1992;30:257–259.
   PubMed Web of Science ®Google Scholar
• Arencibia ZB, Choonara I. Balancing the risks and benefits of the use of over-the-counter pain medications in children. Drug Saf. 2012;35:1119–1125.
   PubMed Web of Science ®Google Scholar
• Cortellini G, Testi S, Severino M, et al. Aspirin challenge/desensitisation before coronary stenting in subjects with history of hypersensitivity. A pragmatic approach. Eur Ann Allergy Clin Immunol. 2012;44:160–162.
   PubMedGoogle Scholar
• Cortellini G, Romano A, Santucci A, et al. Clinical approach on challenge and desensitization procedures with aspirin in patients with ischemic heart disease and nonsteroidal anti-inflammatory drug hypersensitivity. Allergy. 2017;72:498–506.
   PubMed Web of Science ®Google Scholar
• Doña I, Blanca-López N, Torres MJ, et al. Drug hypersensitivity reactions: response patterns, drug involved, and temporal variations in a large series of patients. J Investig Allergol Clin Immunol. 2012;22:363–371.
   PubMed Web of Science ®Google Scholar
• Messaad D, Sahla H, Benahmed S, et al. Drug provocation testing with a history suggesting an immediate drug hypersensitivity reaction. Ann Intern Med. 2004;140:1001–1006.
   PubMed Web of Science ®Google Scholar
• Gómez F, Perkins JR, García-Martín E, et al. Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs. Curr Opin Allergy Clin Immunol. 2015;15:285–293.
   PubMed Web of Science ®Google Scholar
• Kowalski ML, Makowska JS, Blanca M, et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAID) - classification, diagnosis and management: review of the EAACI/ENDA(#) and GA2LEN/HANNA. Allergy. 2011;66:818–829.
   PubMed Web of Science ®Google Scholar
• Kowalski ML, Asero R, Bavbek S, et al. Classification and practical approach to the diagnosis and management of hypersensitivity to nonsteroidal anti-inflammatory drugs. Allergy. 2013;68:1219–1232.
   PubMed Web of Science ®Google Scholar
• Ayuso P, Blanca-López N, Doña I, et al. Advanced phenotyping in hypersensitivity drug reactions to NSAID. Clin Exp Allergy. 2013;43:1097–1109.
   PubMed Web of Science ®Google Scholar
• Szczeklik A, Nizankowska-Mogilnicka E, Sanak M. Hypersensitivity to aspirin and nonsteroidal anti-inflammatory drugs. In: Adkinson N, Busse WW, Bochner BS, et al., editors. Middleton’s allergy 7th edition. USA: Philadelphia; 2009. p. 1227–1243.
   Google Scholar
• Capone ML, Tacconelli S, Di Francesco LD, et al. Pharmacodynamic of cyclooxygenase inhibitors. Prostaglandins Other Lipid Mediat. 2007;82:85–94.
   PubMed Web of Science ®Google Scholar
• Doña I, Blanca-López N, Cornejo-García JA, et al. Characteristics of subjects experiencing hypersensitivity to non-steroidal anti-inflammatory drugs: patterns of response. Clin Exp Allergy. 2011;41:86–95.
   PubMed Web of Science ®Google Scholar
• Mastalerz L, Setkowicz M, Sanak M, et al. Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma. J Allergy Clin Immunol. 2004;113:771–775.
   PubMed Web of Science ®Google Scholar
• Campo P, Ayuso P, Salas M, et al. Mediator release after nasal aspirin provocation supports different phenotypes in subjects with hypersensitivity reactions to NSAIDs. Allergy. 2013;68:1001–1007.
   PubMed Web of Science ®Google Scholar
• Canto MG, Andreu I, Fernandez J, et al. Selective immediate hypersensitivity reactions to NSAID. Curr Opin Allergy Clin Immunol. 2009;9:293–297.
   PubMed Web of Science ®Google Scholar
• Carmona MJ, Blanca M, Garcia A, et al. Intolerance to piroxicam in patients with adverse reactions to nonsteroidal anti-inflammatory drugs. J Allergy Clin Immunol. 1992;90:873–879.
   PubMed Web of Science ®Google Scholar
• Gomez E, Blanca-Lopez N, Torres MJ, et al. Immunoglobulin E-mediated immediate allergic reactions to dipyrone: value of basophil activation test in the identification of patients. Clin Exp Allergy. 2009;39:1217–1224.
   PubMed Web of Science ®Google Scholar
• Pichler WJ. Delayed drug hypersensitivity reactions. Ann Intern Med. 2003;139:683–693.
   PubMed Web of Science ®Google Scholar
• Gomez E, Torres MJ, Mayorga C, et al. Immunologic evaluation of drug allergy. Allergy Asthma Immunol Res. 2012;4:251–263.
   PubMed Web of Science ®Google Scholar
• Szczeklik A, Nizankowska E, Duplaga M. Natural history of aspirin-induced asthma. AIANE Investigators. European Network on Aspirin-Induced Asthma. Eur Respir J. 2000;16:432–436.
   PubMed Web of Science ®Google Scholar
• Quiralte J, Blanco C, Castillo R, et al. Intolerance to non-steroidal anti-inflammatory drugs: results of controlled drug challenges in 98 patients. J Allergy Clin Immunol. 1996;98:678–685.
   PubMed Web of Science ®Google Scholar
• Pérez-Alzate D, Blanca-López N, Doña I, et al. Asthma and rhinitis induced by selective immediate reactions to paracetamol and non-steroidal anti-inflammatory drugs in aspirin tolerant subjects. Front Pharmacol. 2016;7:215.
   PubMed Web of Science ®Google Scholar
• Asero R. Multiple nonsteroidal anti-inflammatory drug-induced cutaneous disease: what differentiates patients with and without underlying cHDRonic spontaneous urticaria? Int Arch Allergy Immunol. 2014;163:114–118.
   PubMed Web of Science ®Google Scholar
• Asero R. Multiple sensitivity to NSAID. Allergy. 2000;55:893–894.
   PubMed Web of Science ®Google Scholar
• Arikoglu T, Aslan G, Yildirim DD, et al. Discrepancies in the diagnosis and classification of non steroidal anti-inflammatory drug hypersensitivity reactions in children. Allergol Int. 2017;66:418–424.
   PubMed Web of Science ®Google Scholar
• Cavkaytar O, Arik Yilmaz E, Karaatmaca B, et al. Different phenotypes of non-steroidal anti-inflammatory drug hypersensitivity during childhood. Int Arch Allergy Immunol. 2015;167:211–221.
   PubMed Web of Science ®Google Scholar
• Blanca-López N, Barrionuevo E, Andreu I, et al. Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs: from phenotyping to genotyping. Curr Opin Allergy Clin Immunol. 2014;14:271–277.
   PubMed Web of Science ®Google Scholar
• Walters KM, Woessner KM. An overview of nonsteroidal antiinflammatory drug reactions. Immunol Allergy Clin North Am. 2016;36:625–641.
   PubMed Web of Science ®Google Scholar
• Shiohara T. Fixed drug eruption: pathogenesis and diagnostic tests. Curr Opin Allergy Clin Immunol. 2009;9:316–321.
   PubMed Web of Science ®Google Scholar
• Blanca-López N, Pérez-Sánchez N, Agúndez JA, et al. Allergic reactions to dypirone: immediate and delayed responses. Int Arch Allergy Immunol. 2016;169:223–230.
   PubMed Web of Science ®Google Scholar
• Pérez-Alzate D, Cornejo-García JA, Pérez-Sánchez N, et al. Immediate reactions to more than one NSAID must not be considered as cross-hypersensitivity unless ASA tolerance is verified. J Investig Allergol Clin Immunol. 2017;27:32–39.
   PubMed Web of Science ®Google Scholar
• Viola M, Rumi G, Valluzzi LR, et al. Assessing potential determinants of positive provocation tests in subjects with NSAID hypersensitivity. Clin Exp Allergy. 2011;41:96–103.
   PubMed Web of Science ®Google Scholar
• Asero R. Detection of aspirin reactivity in patients with pyrazolones-induced skin disorders. Allergy. 1998;53:214–215.
   PubMed Web of Science ®Google Scholar
• Zambonino MA, Torres MJ, Muñoz C, et al. Drug provocation tests in the diagnosis of hypersensitivity reactions to non-steroidal anti-inflammatory drugs in children. Pediatr Allergy Immunol. 2013;24:151–159.
   PubMed Web of Science ®Google Scholar
• Yilmaz O, Ertoy Karagol IH, Bakirtas A, et al. Challenge-proven nonsteroidal anti-inflammatory drug hypersensitivity in children. Allergy. 2013;68:1555–1561.
   PubMed Web of Science ®Google Scholar
• Calvo Campoverde K, Giner-Muñoz MT, Martínez Valdez L, et al. Hypersensitivity reactions to non-steroidal anti-inflammatory drugs and tolerance to alternative drugs. An Pediatr (Barc). 2016;84:148–153.
   PubMed Web of Science ®Google Scholar
• Goeschke B, Braathen LR. Acute generalized exanthematic pustulosis: a case and an overview of side effects affecting the skin caused by celecoxib and other COX-2 inhibitors reported so far. Dermatology. 2004;209:53–56.
   PubMed Web of Science ®Google Scholar
• Himly M, Jahn-Schmid B, Pittertschatscher K, et al. IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone. J Allergy Clin Immunol. 2003;111:882–888.
   PubMed Web of Science ®Google Scholar
• Çelik GE, ScHDRoeder JT, Hamilton RH, et al. Effect of in vitro aspirin stimulation on basophils in patients with aspirin exacerbated respiratory disease. Clin Exp Allergy. 2009;39:1522–1531.
   PubMed Web of Science ®Google Scholar
• Blanca-López N, Bogas G, Doña I, et al. ASA must be given to classify multiple NSAID-hypersensitivity patients as selective or cross-intolerant. Allergy. 2016;71:576–578.
   PubMed Web of Science ®Google Scholar
• Nizankowska-Mogilnicka E, Bochenek G, Mastalerz L, et al. EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity. Allergy. 2007;62:1111–1118.
   PubMed Web of Science ®Google Scholar
• Lee DK, Haggart K, Lipworth BJ. Reproducibility of response to nasal lysine-aspirin challenge in patients with aspirin-induced asthma. Ann Allergy Asthma Immunol. 2004;93:185–188.
   PubMed Web of Science ®Google Scholar
• Alonso-Llamazares A, Martinez-Cócera C, Domínguez-Ortega J, et al. Nasal provocation test (NPT) with aspirin: a sensitive and safe method to diagnose aspirin-induced asthma (AIA). Allergy. 2002;57:632–635.
   PubMed Web of Science ®Google Scholar
• Hsieh CW, Lee JW, Liao EC, et al. A disease marker for aspirin-induced chronic urticaria. Int J Mol Sci. 2014;15:12591–12603.
   PubMed Web of Science ®Google Scholar
• Cornejo-García JA, Oussalah A, Blanca M, et al. Genetic predictors of drug hypersensitivity. Curr Pharm Des. 2016;22:6725–6733.
   PubMed Web of Science ®Google Scholar
• Blanca-Lopez N, Torres MJ, Doña I, et al. Value of the clinical history in the diagnosis of urticaria/angioedema induced by NSAID with cross-intolerance. Clin Exp Allergy. 2013;43:85–91.
   PubMed Web of Science ®Google Scholar
• Blanca M, Pérez E, Garcia JJ, et al. Angioedema and IgE antibodies to aspirin: a case report. Ann Allergy. 1989;62:295–298.
   PubMedGoogle Scholar
• De Paramo BJ, Gancedo SQ, Cuevas M, et al. Paracetamol (acetaminophen) hypersensitivity. Ann Allergy Asthma Immunol. 2000;85:508–511.
   PubMed Web of Science ®Google Scholar
• Barbaud A. Skin testing and patch testing in non-IgE-mediated drug allergy. Curr Allergy Asthma Rep. 2014;14:442.
   PubMed Web of Science ®Google Scholar
• Bruynzeel DP, Ferguson J, Andersen K, et al. Photopatch testing: a consensus methodology for Europe. J Eur Acad Dermatol Venereol. 2004;18:679–682.
   PubMed Web of Science ®Google Scholar
• Holzle E, Lehmann P, Neumann N. Phototoxic and photoallergic reactions. J Dtsch Dermatol Ges. 2009;7:643–649.
   PubMed Web of Science ®Google Scholar
• Andri L, Senna G, Betteli C, et al. Tolerability of nimesulide in aspirin-sensitive patients. Ann Allergy. 1994;72:29–32.
   PubMedGoogle Scholar
• Bavbek S, Celik G, Ozer F, et al. Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib. J Asthma. 2004;41:67–75.
   PubMed Web of Science ®Google Scholar
• Hassani A, Ponvert C, Karila C, et al. Hypersensitivity to cyclooxygenase inhibitory drugs in children: a study of 164 cases. Eur J Dermatol. 2008;18:561–565.
   PubMed Web of Science ®Google Scholar
• Ispano M, Fontana A, Scibilia J, et al. Oral challenge with alternative nonsteropdal anti-inflamatory drugs (NSAID) and paracetamol in patients intolerant to these agents. Drugs. 1993;46:253–256.
   PubMedGoogle Scholar
• Sharir M. Exacerbation of asthma by topical diclofenac. Arch Ophthalmol. 1997;115:294–295.
   PubMedGoogle Scholar
• Jenkins C, Costello J, Hodge L. Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. BMJ. 2004;328:434.
   PubMed Web of Science ®Google Scholar
• Tan JHY, Hsu AAL. Nonsteroidal anti-inflammatory drug (NSAID) exacerbated respiratory disease phenotype: topical NSAID and asthma control - a possible oversight link. Respir Med. 2016;118:1–3.
   PubMed Web of Science ®Google Scholar
• Stevenson DD. Aspirin and NSAID sensitivity. Immunol Allergy Clin North Am. 2004;24:491–505.
   PubMed Web of Science ®Google Scholar
• Szczeklik A, Gryglewsky RJ, Czerniawska-Mysik G. Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin sensitive patients. Br Med J. 1975;1:67–69.
   PubMed Web of Science ®Google Scholar
• Delaney JC. The diagnosis of aspirin idiosyncrasy by analgesic challenge. Clin Allergy. 1976;6:177–181.
   PubMedGoogle Scholar
• Davis R, Brogden RN. Nimesulide: an update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs. 1994;48:431–454.
   PubMed Web of Science ®Google Scholar
• Bavbek S, Celik G, Ediger D, et al. The use of nimesulide in patients with acetylsalicylic acid and nonsteroidal anti-inflammatory drug intolerance. J Asthma. 1999;36:657–663.
   PubMed Web of Science ®Google Scholar
• Clemett D, Goa KL. Celecoxib: a review of its use in osteoartHDRitis, rheumatoid arthritis and acute pain. Drugs. 2000;59:957–980.
   PubMed Web of Science ®Google Scholar
• Dahlén B, Szczeklik A, Murray JJ. Celecoxib in patients with asthma and aspirin intolerance. The celecoxib in aspirin-intolerant astha study group. N Engl J Med. 2001;344:142.
   PubMed Web of Science ®Google Scholar
• Woesner KM, Simon RA, Stevenson D. The safety of celecoxib in patients with aspirin sensitive asthma. Arthritis Rheum. 2002;46:2201–2206.
   PubMed Web of Science ®Google Scholar
• Martin-Garcia C, Hinojosa M, Berges P, et al. Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. J Investig Allergol Clin Immunol. 2003;13:20–25.
   PubMed Web of Science ®Google Scholar
• Koschel D, Weber CN, Höffken G. Tolerability to etoricoxib in patients with aspirin-exacerbated respiratory disease. J Investig Allergol Clin Immunol. 2013;23:275–280.
   PubMed Web of Science ®Google Scholar
• Berges-Gimeno MP, Simon RA, Stevenson DD. Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2003;111:180–186.
   PubMed Web of Science ®Google Scholar
• Llanora GV, Loo EXL, Gerez IFA, et al. Etoricoxib: a safe alternative for NSAID intolerance in Asian patients. Asian Pac J Allergy Immunol. 2013;31:330–333.
   PubMed Web of Science ®Google Scholar
• Kang LW, Kidon MI, Chin CW, et al. Severe anaphylactic reaction to ibuprofen in a child with recurrent urticaria. Pediatrics. 2007;120:e742–4.
   PubMed Web of Science ®Google Scholar
• Doña I, Blanca-López N, Jagemann LR, et al. Response to a selective COX-2 inhibitor in patients with urticaria/angioedema induced by nonsteroidal anti-inflammatory drugs. Allergy. 2011;66:1428–1433.
   PubMed Web of Science ®Google Scholar
• Inomata N, Osuna H, Yamaguchi J, et al. Safety of cyclooxygenase-2 inhibitors and a basic non-steroidal anti-inflammatory drug (NSAID) in Japanese patients with NSAID-induced urticaria and/or angioedema: comparison of meloxicam, etodolac and tiaramide. J Dermatol. 2007;34:172–177.
   PubMed Web of Science ®Google Scholar
• Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G. Clinical patterns of hypersensitivity to NSAID and pathogenesis. J Allergy Clin Immunol. 1977;60:276–284.
   PubMed Web of Science ®Google Scholar
• Barles PG, Duce GF, Portillo OJ, et al. Adverse reaction of acetaminophen as an alternative analgesic in ASA triad. Allergol Immunopathol (Madr). 1988;16:321–325.
   PubMed Web of Science ®Google Scholar
• Davies NM, McLachlan AJ. Properties and features of nabumetone. Drugs. 2000;59:25–33.
   PubMed Web of Science ®Google Scholar
• Prieto A, De Barrio M, Martín E, et al. Tolerability to nabumetone and meloxicam in patients with nonsteroidal anti-inflammatory drug intolerance. J Allergy Clin Immunol. 2007;119:960–964.
   PubMed Web of Science ®Google Scholar
• Bavbek S, Dursun AB, Dursun E, et al. Safety of meloxicam in aspirin-hypersensitive patients with asthma and/or nasal polyps. A challenge-proven study. Int Arch Allergy Immunol. 2007;142:64–69.
   PubMed Web of Science ®Google Scholar
• Ward A, Brodgen RN. Nimesulide: a preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states. Drugs. 1988;36:732–753.
   PubMed Web of Science ®Google Scholar
• Bianco S, Robuschi M, Petrigni G, et al. Efficacy and tolerability of nimesulide in asthmatic patients intolerant to aspirin. Drugs. 1993;46:253–256.
   PubMedGoogle Scholar
• Gyllfors P, Bochenek G, Overholt J, et al. Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. J Allergy Clin Immunol. 2003;111:1116–1121.
   PubMed Web of Science ®Google Scholar
• El Miedany Y, Youssef S, Ahmed I, et al. Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol. 2006;97:105–109.
   PubMed Web of Science ®Google Scholar
• Confino-Cohen R, Goldberg A. Safe full-dose one-step nabumetone challenge in patients with nonsteroidal anti-inflammatory drug hypersensitivity. Allergy Asthma Proc. 2003;24:281–284.
   PubMed Web of Science ®Google Scholar
• Kim YJ, Lim KH, Kim MY, et al. Cross-reactivity to acetaminophen and celecoxib according to the type of nonsteroidal anti-inflammatory drug hypersensitivity. Allergy Asthma Immunol Res. 2014;6:156–162.
   PubMed Web of Science ®Google Scholar
• Nabe T, Hashii H, Matsubara S, et al. A tiramide derivate, 5-Chloro-3-(4-hydroxypiperadionocarbonylmethyl-2-one(HPR-611), a potent inhibitor of anaphylactic chemical mediator release: a distinctive feature from disodium crhomoglycate. J Pharmacobiodyn. 1992;15:673–679.
   PubMedGoogle Scholar
• Gonzalo-Garijo MA, Cordobés-Duran C, Lamilla-Yerga AM, et al. Severe immediate reaction to nabumetone. J Investig Allergol Clin Immunol. 2007;17:274–276.
   PubMed Web of Science ®Google Scholar
• Pérez-Calderón R, Gonzalo-Garijo MA, Pérez-Rangel I, et al. Fixed drug eruption due to nabumetone in a patient with previous fixed drug eruptions due to naproxen. J Investig Allergol Clin Immunol. 2011;21:153–154.
   PubMed Web of Science ®Google Scholar
• Bagheri H, Lhaubet V, Montastruc JL, et al. Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data. Drug Saf. 2000;22:339–349.
   PubMed Web of Science ®Google Scholar
• Stevenson DD, Pleskow WW, Simon RA, et al. Aspirin-sensitive rhinosinusitis asthma: a double-blind crossover study of treatment with aspirin. J Allergy Clin Immunol. 1984;73:500–507.
   PubMed Web of Science ®Google Scholar
• Kowalski ML, Wardzyńska A, Makowska JS. Clinical trials of aspirin treatment after desensitization in aspirin-exacerbated respiratory disease. Immunol Allergy Clin North Am. 2016;36:705–717.
   PubMed Web of Science ®Google Scholar
• Rozsasi A, Polzehl D, Deutschle T, et al. Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily. Allergy. 2008;63:1228–1234.
   PubMed Web of Science ®Google Scholar
• Bergman KC, Zuberbier T, Church MK. Omalizumab in the treatment of aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract. 2015;3:459–460.
   PubMed Web of Science ®Google Scholar
• Ta V, White AA. Survey-defined patient experiences with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol Pract. 2015;3:711–718.
   PubMed Web of Science ®Google Scholar
• Grzelewska-Rzymowska I, Roznlecki J, Szmidt M. Aspirin desensitization in patients with aspirin-induced urticaria and angioedema. Allergol Immunopathol (Madr). 1988;16:305–308.
   PubMed Web of Science ®Google Scholar
• Wong JT, Nagy CS, Krinzman SJ, et al. Rapid oral challenge-desensitization for patients with aspirin-related urticaria-angioedema. J Allergy Clin Immunol. 2000;105:997–1001.
   PubMed Web of Science ®Google Scholar
• Slowik SM, Slavin RG. Aspirin desensitization in a patient with aspirin sensitivity and cHDRonic idiopathic urticaria. Ann Allergy Asthma Immunol. 2009;102:171–172.
   PubMed Web of Science ®Google Scholar
• Scherer K, Brockow K, Aberer W, et al. Desensitisation in delayed drug hypersensitivity reactions. An EAACI position paper of the Drug Allergy Interest Group. Allergy. 2013;68:844–852.
   PubMed Web of Science ®Google Scholar