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Review

Advances in imaging and molecular diagnostics of ocular tuberculosis and selected observations from the Collaborative Ocular Tuberculosis Study (COTS)

ORCID Icon, , , &
Pages 361-371 | Received 29 May 2018, Accepted 30 Nov 2018, Published online: 16 Dec 2018

References

  • Lawn SD, Zumla AI. Tuberculosis. Lancet Lond Engl. 2011;378:57–72.
  • Gupta V, Gupta A, Rao NA. Intraocular tuberculosis–an update. Surv Ophthalmol. 2007;52:561–587.
  • Gupta V, Shoughy SS, Mahajan S, et al. Clinics of ocular tuberculosis. Ocul Immunol Inflamm. 2015;23:14–24.
  • Gupta V, Bansal R, Gupta A. Continuous progression of tubercular serpiginous-like choroiditis after initiating antituberculosis treatment. Am J Ophthalmol. 2011;152:857–863.e2.
  • Gupta A, Bansal R, Gupta V, et al. Ocular signs predictive of tubercular uveitis. Am J Ophthalmol. 2010;149:562–570.
  • Bansal R, Gupta A, Gupta V, et al. Tubercular serpiginous-like choroiditis presenting as multifocal serpiginoid choroiditis. Ophthalmology. 2012;119:2334–2342.
  • Bodaghi B, LeHoang P. Ocular tuberculosis. Curr Opin Ophthalmol. 2000;11:443–448.
  • Ang M, Hedayatfar A, Zhang R, et al. Clinical signs of uveitis associated with latent tuberculosis. Clin Exp Ophthalmol. 2012;40:689–696.
  • Nazari Khanamiri H, Rao NA. Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis. Surv Ophthalmol. 2013;58:203–232.
  • Agrawal R, Kee AR, Ang L, et al. Tuberculosis or sarcoidosis: opposite ends of the same disease spectrum? Tuberculosis (Edinburgh, Scotland). 2016;98:21–26.
  • Agarwal A, Agrawal R, Gunasekaran DV, et al. The Collaborative Ocular Tuberculosis Study (COTS)-1 report 3: polymerase chain reaction in the diagnosis and management of tubercular uveitis: global trends. Ocul Immunol Inflamm. 2017 Dec 20:1-9. doi: https://doi.org/10.1080/09273948.2017.1406529. [Epub ahead of print].
  • Gupta A, Sharma A, Bansal R, et al. Classification of intraocular tuberculosis. Ocul Immunol Inflamm. 2015;23:7–13.
  • Agarwal A, Mahajan S, Khairallah M, et al. Multimodal imaging in ocular tuberculosis. Ocul Immunol Inflamm. 2017;25:134–145.
  • Aggarwal K, Mulkutkar S, Mahajan S, et al. Role of ultra-wide field imaging in the management of tubercular posterior uveitis. Ocul Immunol Inflamm. 2016;24:631–636.
  • Campbell JP, Leder HA, Sepah YJ, et al. Wide-field retinal imaging in the management of noninfectious posterior uveitis. Am J Ophthalmol. 2012;154:908–911.e2.
  • Dickson D, Agarwal A, Sadiq MA, et al. Assessment of vitreous haze using ultra-wide field retinal imaging. J Ophthalmic Inflamm Infect. 2016;6:35.
  • Tsui I, Kaines A, Schwartz S. Patterns of periphlebitis in intermediate uveitis using ultra wide field fluorescein angiography. Semin Ophthalmol. 2009;24:29–33.
  • Kaines A, Tsui I, Sarraf D, et al. The use of ultra wide field fluorescein angiography in evaluation and management of uveitis. Semin Ophthalmol. 2009;24:19–24.
  • Hassan M, Agarwal A, Afridi R, et al. The role of optical coherence tomography angiography in the management of uveitis. Int Ophthalmol Clin. 2016;56:1–24.
  • Hassenstein A, Bialasiewicz AA, Richard G. Optical coherence tomography in uveitis patients. Am J Ophthalmol. 2000;130:669–670.
  • Ciardella AP, Prall FR, Borodoker N, et al. Imaging techniques for posterior uveitis. Curr Opin Ophthalmol. 2004;15:519–530.
  • Invernizzi A, Agarwal A, Cozzi M, et al. Enhanced depth imaging optical coherence tomography features in areas of choriocapillaris hypoperfusion. Retina (Philadelphia, Pa). 2016;36:2013–2021.
  • Bansal R, Basu S, Gupta A, et al. Imaging in tuberculosis-associated uveitis. Indian J Ophthalmol. 2017;65:264–270.
  • Agarwal A, Agrawal R, Khandelwal N, et al. Choroidal structural changes in tubercular multifocal serpiginoid choroiditis. Ocul Immunol Inflamm. 2018;26(6):838–844. doi: https://doi.org/10.1080/09273948.2017.1370650.
  • Invernizzi A, Mapelli C, Viola F, et al. Choroidal granulomas visualized by enhanced depth imaging optical coherence tomography. Retina (Philadelphia, Pa). 2015;35:525–531.
  • Invernizzi A, Agarwal A, Mapelli C, et al. Longitudinal follow-up of choroidal granulomas using enhanced depth imaging optical coherence tomography. Retina (Philadelphia, Pa). 2017;37:144–153.
  • Higashide T, Akao N, Shirao E, et al. Optical coherence tomographic and angiographic findings of a case with subretinal toxocara granuloma. Am J Ophthalmol. 2003;136:188–190.
  • Salman A, Parmar P, Rajamohan M, et al. Optical coherence tomography in choroidal tuberculosis. Am J Ophthalmol. 2006;142:170–172.
  • Agrawal R, Xin W, Keane PA, et al. Optical coherence tomography angiography: a non-invasive tool to image end-arterial system. Expert Rev Med Devices. 2016;13:519–521.
  • Hassan M, Sadiq MA, Halim MS, et al. Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography. Int J Retina Vitreous. 2017;3:27.
  • Mandadi SKR, Agarwal A, Aggarwal K, et al. Novel Findings On Optical Coherence Tomography Angiography In Patients With Tubercular Serpiginous-Like Choroiditis. Retina (Philadelphia, Pa). 2017;37:1647–1659.
  • Agarwal A, Aggarwal K, Deokar A, et al. Optical coherence tomography angiography features of paradoxical worsening in tubercular multifocal serpiginoid choroiditis. Ocul Immunol Inflamm. 2016;24:621–630.
  • Invernizzi A, Agarwal A, Di Nicola M, et al. Choroidal neovascular membranes secondary to intraocular tuberculosis misdiagnosed as neovascular age-related macular degeneration. Eur J Ophthalmol. 2018 Mar;28(2):216–224.
  • Bansal R, Bansal P, Gupta A, et al. Diagnostic challenges in inflammatory choroidal neovascular membranes. Ocul Immunol Inflamm. 2017;25:554–562.
  • Yee HY, Keane PA, Ho SL, et al. Optical coherence tomography angiography of choroidal neovascularization associated with tuberculous serpiginous-like choroiditis. Ocul Immunol Inflamm. 2016;24:699–701.
  • Aggarwal K, Agarwal A, Sharma A, et al. Detection of type 1 choroidal neovascular membranes using optical coherence tomography angiography in tubercular posterior uveitis. Retina. 2018 Apr 23. doi: https://doi.org/10.1097/IAE.0000000000002176. [Epub ahead of print].
  • Arora SK, Gupta V, Gupta A, et al. Diagnostic efficacy of polymerase chain reaction in granulomatous uveitis. Tuber Lung Dis Off J Int Union Tuberc Lung Dis. 1999;79:229–233.
  • Gupta V, Arora S, Gupta A, et al. Management of presumed intraocular tuberculosis: possible role of the polymerase chain reaction. Acta Ophthalmol Scand. 1998;76:679–682.
  • Biswas J, Kazi MS, Agarwal VA, et al. Polymerase chain reaction for Mycobacterium tuberculosis DNA detection from ocular fluids in patients with various types of choroiditis in a referral eye center in India. Indian J Ophthalmol. 2016;64:904–907.
  • Singh R, Toor P, Parchand S, et al. Quantitative polymerase chain reaction for Mycobacterium tuberculosis in so-called Eales’ disease. Ocul Immunol Inflamm. 2012;20:153–157.
  • Bhagya S, Lalitha P, Kumar AL, et al. Polymerase chain reaction and its correlation with clinical features and treatment response in tubercular uveitis. Ocul Immunol Inflamm.  2018;26(6):845–852.
  • Verma A, Biswas J, Dhanurekha L, et al. Detection of Mycobacterium tuberculosis with nested polymerase chain reaction analysis in enucleated eye ball in Eales’ disease. Int Ophthalmol. 2016;36:413–417.
  • Bhuibhar SS, Biswas J. Nested PCR-positive tubercular ampiginous choroiditis: a case report. Ocul Immunol Inflamm. 2012;20:303–305.
  • Shetty SB, Biswas J, Murali S. Real-time and nested polymerase chain reaction in the diagnosis of multifocal serpiginoid choroiditis caused by Mycobacterium tuberculosis - a case report. J Ophthalmic Inflamm Infect. 2014;4:29.
  • Santos FFD, Ag C, Souza AVD, et al. Real-time PCR in infectious uveitis as an alternative diagnosis. Arq Bras Oftalmol. 2011;74:258–261.
  • Balne PK, Basu S, Sharma S. Loop-mediated isothermal amplification for rapid diagnosis of tubercular uveitis. JAMA Ophthalmol. 2015;133:225–226.
  • Balne PK, Basu S, Rath S, et al. Loop mediated isothermal amplification assay using hydroxy naphthol blue, conventional polymerase chain reaction and real-time PCR in the diagnosis of intraocular tuberculosis. Indian J Med Microbiol. 2015;33:568–571.
  • Sharma K, Bansal R, Sharma A, et al. Loop-mediated isothermal amplification for rapid diagnosis of tubercular uveitis. JAMA Ophthalmol. 2014;132:777–778.
  • Bansal R, Sharma K, Gupta A, et al. Detection of Mycobacterium tuberculosis genome in vitreous fluid of eyes with multifocal serpiginoid choroiditis. Ophthalmology. 2015;122:840–850.
  • Flesch IE, Kaufmann SH. Role of cytokines in tuberculosis. Immunobiology. 1993;189:316–339.
  • Giacomini E, Iona E, Ferroni L, et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol (Baltimore, MD). 1950;2001(166):7033–7041.
  • Redford PS, Murray PJ, O’Garra A. The role of IL-10 in immune regulation during M. Tuberculosis Infection Mucosal Immunol. 2011;4:261–270.
  • Mollo B, Jouveshomme S, Philippart F, et al. Biological markers in the diagnosis of tuberculous pleural effusion. Ann Biol Clin (Paris). 2017;75:19–27.
  • Skouras VS, Kalomenidis I. Pleural fluid tests to diagnose tuberculous pleuritis. Curr Opin Pulm Med. 2016;22:367–377.
  • La Distia Nora R, Walburg KV, van Hagen PM, et al. Retinal pigment epithelial cells control early mycobacterium tuberculosis infection via interferon signaling. Invest Ophthalmol Vis Sci. 2018;59:1384–1395.
  • Ang M, Cheung G, Vania M, et al. Aqueous cytokine and chemokine analysis in uveitis associated with tuberculosis. Mol Vis. 2012;18:565–573.
  • Abu El-Asrar AM, Struyf S, Kangave D, et al. Cytokine and CXC chemokine expression patterns in aqueous humor of patients with presumed tuberculous uveitis. Cytokine. 2012;59:377–381.
  • Valentincic NV, Jdf DG-M, Kraut A, et al. Intraocular and serum cytokine profiles in patients with intermediate uveitis. Mol Vis. 2011;17:2003–2010.
  • Agarwal A, Deokar A, Sharma R, et al. Longitudinal analysis of Serum Cytokine 1 profile among patients with tubercular 2 multifocal serpiginoid choroiditis: a pilot study. Eye (Lond). 2018 Sep 5. doi: https://doi.org/10.1038/s41433-018-0157-5. [Epub ahead of print].
  • Agrawal R, Gunasekeran DV, Grant R, et al. Clinical features and outcomes of patients with tubercular uveitis treated with antitubercular therapy in the Collaborative Ocular Tuberculosis Study (COTS)-1. JAMA Ophthalmol. 2017;135:1318–1327.
  • Gunasekeran DV, Agrawal R, Agarwal A, et al. The Collaborative Ocular Tuberculosis Study (COTS)-1: a multinational review of 251 patients with tubercular retinal vasculitis. Retina. 2018 Apr 24. doi: https://doi.org/10.1097/IAE.0000000000002194. [Epub ahead of print].

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