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Expert Review of Respiratory Medicine Volume 12, 2018 - Issue 12
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Editorial

Sex, smoking and body mass index: do they aid in uncovering the complex mechanisms behind airway hyperresponsiveness?

Andreas A. TeferraDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsORCID Iconhttp://orcid.org/0000-0002-8052-6605View further author information
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Judith M. VonkDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsCorrespondence[email protected]
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H. Marike BoezenDepartment of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsView further author information
Pages 989-991 | Received 01 Jun 2018, Accepted 25 Oct 2018, Published online: 31 Oct 2018

References

  • Cockcroft DW, Davis BE. Mechanisms of airway hyperresponsiveness. J Allergy Clin Immunol. 2006;118(3):551–559.
  • Fuseini H, Newcomb DC. Mechanisms driving gender differences in asthma. Curr Allergy Asthma Rep. 2017 Mar 23;17(3):19.
  • Uekert SJ, Akan G, Evans MD, et al. Sex-related differences in immune development and the expression of atopy in early childhood. J Allergy Clin Immunol. 2006 Dec;118(6):1375–1381.
  • McKenzie R, Burton MD, Royce SG, et al. Age and sex influences on airway hyperresponsiveness. J Asthma. 2010;47(6):651–654.
  • Cai Y, Zhou J, Webb DC. Estrogen stimulates Th2 cytokine production and regulates the compartmentalisation of eosinophils during allergen challenge in a mouse model of asthma. Int Arch Allergy Immunol. 2012;158(3):252–260.
  • Troisi RJ, Speizer FE, Willett WC, et al. Menopause, postmenopausal estrogen preparations, and the risk of adult-onset asthma. A prospective cohort study. Am J Respir Crit Care Med. 1995 Oct 20;152(4 Pt 1):1183–1188.
  • Leynaert B, Bousquet J, Henry C, et al. Is bronchial hyperresponsiveness more frequent in women than in men? A population-based study. Am J Respir Crit Care Med. 1997 Nov;156(5):1413–1420.
  • Hibbert ME, Couriel JM, Landau LI. Changes in lung, airway, and chest wall function in boys and girls between 8 and 12 yr. J Appl Physiol. 1984 Aug;57(2):304–308.
  • Zazara DE, Perani CV, Solano ME, et al. Prenatal stress challenge impairs fetal lung development and asthma severity sex-specifically in mice. J Reprod Immunol. 2018 Feb;125:100–105.
  • Hartwig IRV, Bruenahl CA, Ramisch K, et al. Reduced levels of maternal progesterone during pregnancy increase the risk for allergic airway diseases in females only. J Mol Med. 2014;92(10):1093–1104.
  • Shiels MS, Katki HA, Freedman ND, et al. Cigarette smoking and variations in systemic immune and inflammation markers. JNCI J Natl Cancer Inst. 2014 Nov;106(11).
  • Daffonchio L, Hernandez A, Melillo G, et al. Effectiveness of levodropropizine against cigarette smoke-induced airway hyperreactivity: possible mechanism. Eur J Pharmacol. 1993 Apr;228(5–6):257–261.
  • Wylam ME, Sathish V, VanOosten SK, et al. Mechanisms of cigarette smoke effects on human airway smooth muscle. PLoS One. 2015;10(6):e0128778.
  • Moerloose KB, Robays LJ, Maes T, et al. Cigarette smoke exposure facilitates allergic sensitization in mice. Respir Res. 2006 Mar;7:49.
  • Strzelak A, Ratajczak A, Adamiec A, et al. Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: a mechanistic review. Int J Environ Res Public Health. 2018 May 21;15(5):1033.
  • Kou YR, Kwong K, Lee L-Y. Airway inflammation and hypersensitivity induced by chronic smoking. Respir Physiol Neurobiol. 2011 Sep;178(3):395–405.
  • Singh SP, Gundavarapu S, Pena-Philippides JC, et al. Prenatal secondhand cigarette smoke promotes Th2 polarization and impairs goblet cell differentiation and airway mucus formation. J Immunol. 2011 Nov 1;187(9):4542–4552.
  • Paoletti P, Carrozzi L, Viegi G, et al. Distribution of bronchial responsiveness in a general population: effect of sex, age, smoking, and level of pulmonary function. Am J Respir Crit Care Med. 1995 Jun;151(6):1770–1777.
  • Burgess JA, Matheson MC, Diao F, et al. Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort. Eur Respir J. 2017 Sep;50(3):1602181.
  • Litonjua AA, Sparrow D, Celedon JC, et al. Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the normative aging study. Thorax. 2002 Jul;57(7):581–585.
  • Rasmussen F, Hancox RJ, Nair P, et al. Associations between airway hyperresponsiveness, obesity and lipoproteins in a longitudinal cohort. Clin Respir J. 2013 Jul;7(3):268–275.
  • Toennesen LL, Bjerregaard A, Porsbjerg C, et al. Overweight in childhood and adolescence: does it lead to airway hyperresponsiveness in adulthood? J Asthma. 2018;55(2):137–144.
  • Pakhale S, Baron J, Dent R, et al. Effects of weight loss on airway responsiveness in obese adults with asthma. Chest. 2015 Jun;147(6):1582–1590.
  • MacDonald KD, Moran AR, Scherman AJ, et al. Maternal high-fat diet in mice leads to innate airway hyperresponsiveness in the adult offspring. Physiol Rep. 2017 Mar;5(5):e13082.

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