The Impact of Functional Strength Training on Muscle Strength and Mobility in Children with Spastic Cerebral Palsy – A Systematic Review and Meta-Analysis

References

• Stavsky M, Mor O, Mastrolia SA, Greenbaum S, Than NG, Erez O. Cerebral palsy—trends in epidemiology and recent development in prenatal mechanisms of disease, treatment, and prevention. Front Pediatr. 2017;5:21. doi:10.3389/fped.2017.00021.
   PubMed Web of Science ®Google Scholar
• McIntyre S, Goldsmith S Webb, A, Ehlinger, V, Hollung, S. J., McConnell, K, Arnaud, C, Smithers-Sheedy, H, Oskoui, M, Khandaker, K, et al. The global CP prevalence group. Global prevalence of cerebral palsy: A systematic analysis. Dev Med Child Neurol. 2022;64:1494–1506. doi:10.1111/dmcn.15346
   PubMed Web of Science ®Google Scholar
• Jahan I, Muhit M, Hardianto D, Laryea F, Chhetri AB, Smithers-Sheedy H, McIntyre S, Badawi N, Khandaker G. Epidemiology of cerebral palsy in low- and middle-income countries: preliminary findings from an international multi-centre cerebral palsy register. Develop Med Child Neuro. 2021;63(11):1327–36. doi:10.1111/dmcn.14926.
   PubMed Web of Science ®Google Scholar
• Van Vulpen LF, De Groot S, Rameckers E, Becher JG, Dallmeijer AJ. Improved walking capacity and muscle strength after functional power-training in young children with cerebral palsy. J Neurol Rehabil. 2017;31(9):827–41. doi:10.1177/1545968317723750.
   Google Scholar
• Fosdahl MA, Jahnsen R, Kvalheim K, Holm I. Stretching and progressive resistance exercise in children with cerebral palsy: a randomized controlled trial. Pediatr Phys Ther. 2019;31(3):264–71. doi:10.1097/PEP.0000000000000616.
   PubMed Web of Science ®Google Scholar
• Novak I, Morgan C, Fahey M, Finch-Edmondson M, Galea C, Hines A, Langdon K, Namara MM, Paton MC, Popat H, et al. State of the evidence traffic lights 2019: systematic review of interventions for preventing and treating children with cerebral palsy. Curr Neurol Neurosci Rep. 2020;20(2):1–21. doi:10.1007/s11910-020-1022-z.
   PubMed Web of Science ®Google Scholar
• Ryan JM, Cassidy EE, Noorduyn SG, O’Connell NE. Exercise interventions for cerebral palsy (Review). Cochrane Database Syst Rev. 2017;2017(6):1–158. doi:10.1002/14651858.CD011660.pub2.
   Google Scholar
• Merino-Andrés J, García de Mateos-López A, Damiano DL, Sánchez-Sierra A. Effect of muscle strength training in children and adolescents with spastic cerebral palsy: a systematic review and meta-analysis. Clin Rehabil. 2021;36(1):4–14. doi:10.1177/02692155211040199.
   PubMed Web of Science ®Google Scholar
• Hedgecock JB, Rapport MJ, Sutphin AR. Functional movement, strength, and intervention for an adolescent with cerebral palsy. Pediatr Phys Ther. 2015;27(2):207–14. doi:10.1097/PEP.0000000000000143.
   PubMed Web of Science ®Google Scholar
• Damiano DL, Alter KE, Chambers H. New clinical and research trends in lower extremity management for ambulatory children with cerebral palsy. Phys Med Rehabil Clin N Am. 2009;20(3):469–91. doi:10.1016/j.pmr.2009.04.005.
   PubMed Web of Science ®Google Scholar
• Mockford M, Caulton JM. Systematic review of progressive strength training in children and adolescents with cerebral palsy who are ambulatory. Pediatr Phys Ther. 2008;20(4):318–33. doi:10.1097/PEP.0b013e31818b7ccd.
   PubMedGoogle Scholar
• Damiano DL, Arnold AS, Steele KM, Delp S. Can strength training predictably improve gait kinematics? A pilot study on the effects of hip and knee extensor strengthening on lower-extremity alignment in cerebral palsy. Phys Ther. 2010;90(2):269–79. doi:10.2522/ptj.20090062.
   PubMed Web of Science ®Google Scholar
• Verschuren O, Peterson MD, Balemans A, Hurvitz C, Edward A. Exercise and physical activity recommendations for people with cerebral palsy. Dev Med Child Neurol. 2016;58(8):798–808. doi:10.1111/dmcn.13053.
   PubMed Web of Science ®Google Scholar
• Novak I, Mcintyre S, Morgan C, Campbell L, Dark L, Morton N, Stumbles E, Wilson S, Goldsmith S. A systematic review of interventions for children with cerebral palsy: state of the evidence. Dev Med Child Neurol. 2013;55(10):885–910. doi:10.1111/dmcn.12246.
   PubMed Web of Science ®Google Scholar
• Dodd KJ, Taylor NF, Damiano DL. A systematic review of the effectiveness of strength-training programs for people with cerebral palsy. Arch Phys Med Rehabil. 2002;83(8):1157–64. doi:10.1053/apmr.2002.34286.
   PubMed Web of Science ®Google Scholar
• Carr JH, Shepherd RB. The changing face of neurological rehabilitation. Rev Bras Fisioter. 2006;10(2):147–56. doi:10.1590/S1413-35552006000200003.
   Google Scholar
• Darrah J, Law MC, Pollock N, Wilson B, Russell DJ, Walter SD, Rosenbaum P, Galuppi B. Context therapy: a new intervention approach for children with cerebral palsy. Dev Med Child Neurol. 2011;53(7):615–20. doi:10.1111/j.1469-8749.2011.03959.x.
   PubMed Web of Science ®Google Scholar
• Nogueira-de-Almeida CA, Del Ciampo LA, Ferraz IS, Del Ciampo IR, Contini AA, Ued FD. COVID-19 and obesity in childhood and adolescence: a clinical review. J Pediatr (Rio J). 2020;96(5):546–58. doi:10.1016/j.jped.2020.07.001.
   PubMed Web of Science ®Google Scholar
• Geijen M, Ketelaar M, Sakzewski L, Palisano R, Rameckers E. Defining functional therapy in research involving children with cerebral palsy: a systematic review. Phys Occup Ther Pediatr. 2020;40(2):231–46. doi:10.1080/01942638.2019.1664703.
   PubMed Web of Science ®Google Scholar
• Van Vulpen LF, De Groot S, Ramekins E, Becher JG, Dallmeijer AJ. Improved walking capacity and muscle strength after functional power-training in young children with cerebral palsy. J Neurol Rehabil. 2017;31(9):827–41. doi:10.1177/1545968317723750.
   Google Scholar
• Scholtes VA, Becher JG, Comuth A, Dekkers H, Van Dijk L, Dallmeijer AJ. Effectiveness of functional progressive resistance exercise strength training on muscle strength and mobility in children with cerebral palsy: a randomized controlled trial. Dev Med Child Neurol. 2010;52(6):e107–e13. doi:10.1111/j.1469-8749.2009.03604.x.
   PubMed Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):1–28. doi:10.1371/journal.pmed.1000097.
   Web of Science ®Google Scholar
• Park SI, Kim MS, Choi JD. Effects of concentric and eccentric control exercise on gross motor function and balance ability of paretic leg in children with spastic hemiplegia. J Phys Ther Sci. 2016;28(7):2128–31. doi:10.1589/jpts.28.2128.
   PubMedGoogle Scholar
• Blundell SW, Shepherd RB, Dean CM, Adams R, Cahill B. Functional strength training in cerebral palsy: a pilot study of a group circuit training class for children aged 4–8 years. Clin Rehabil. 2003;17(1):48–57. doi:10.1191/0269215503cr584oa.
   PubMed Web of Science ®Google Scholar
• Dodd KJ, Taylor NF, HK G. A randomized clinical trial of strength training in young people with cerebral palsy. Dev Med Child Neurol. 2003;45(10):652–57. doi:10.1111/j.1469-8749.2003.tb00866.x.
   PubMed Web of Science ®Google Scholar
• Auld ML, Johnston LM. “Strong and steady”: a community-based strength and balance exercise group for children with cerebral palsy. Disabil Rehabil. 2014;36(24):2065–71. doi:10.3109/09638288.2014.891054.
   PubMed Web of Science ®Google Scholar
• Unger M, Faure M, Frieg A. Strength training in adolescent learners with cerebral palsy: a randomized controlled trial. Clin Rehabil. 2006;20(6):469–77. doi:10.1191/0269215506cr961oa.
   PubMed Web of Science ®Google Scholar
• Salem Y, Godwin EM. Effects of task-oriented training on mobility function in children with cerebral palsy. NRE. 2009;24(4):307–13. doi:10.3233/NRE-2009-0483.
   Google Scholar
• Kara OK, Livanelioglu A, Yardimci BN, Soylu AR. The effects of functional progressive strength and power training in children with unilateral cerebral palsy. Pediatr Phys Ther. 2019;31(3):286–95. doi:10.1097/PEP.0000000000000628.
   PubMed Web of Science ®Google Scholar
• Peungsuwan P, Parasin P, Siritaratiwat W, Prasertnu J, Yamauchi J. Effects of combined exercise training on functional performance in children with cerebral palsy: a randomized controlled study. Pediatr Phys Ther. 2017;29(1):39–46. doi:10.1097/PEP.0000000000000338.
   PubMed Web of Science ®Google Scholar
• Cho H-J, Lee B-H. Effect of functional progressive resistance exercise on lower extremity structure, muscle tone, dynamic balance and functional ability in children with spastic cerebral palsy. Children. 2020;7(8):85. doi:10.3390/children7080085.
   PubMedGoogle Scholar
• Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomized and non-randomized studies of health care interventions. J Epidemiol Community Health. 1998;52(6):377–84. doi:10.1136/jech.52.6.377.
   PubMed Web of Science ®Google Scholar
• Burns PB, Rohrich RJ, Chung KC. The levels of evidence and their role in evidence-based medicine. Plast Reconstr Surg Glob Open. 2011;128(1):305. doi:10.1097/PRS.0b013e318219c171.
   Google Scholar
• Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JAC. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343(oct18 2):d5928–d5928. doi:10.1136/bmj.d5928.
   PubMed Web of Science ®Google Scholar
• Higgins JP, Thompson SG, Deeks JJ, Altman D. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–60. doi:10.1136/bmj.327.7414.557.
   PubMed Web of Science ®Google Scholar
• Ross SA, Engsberg JR. Relationships between spasticity, strength, gait, and the GMFM-66 in persons with spastic diplegia cerebral palsy. Arch Phys Med Rehabil. 2007;88(9):1114–20. doi:10.1016/j.apmr.2007.06.011.
   PubMed Web of Science ®Google Scholar
• Gage JR, Novacheck TF. An update on the treatment of gait problems in cerebral palsy. J Pediatr Orthop B. 2001;10(4):265–74. doi:10.1097/01202412-200110000-00001.
   PubMed Web of Science ®Google Scholar
• Scholtes VA, Dallmeijer AJ, Rameckers EA, Verschuren O, Tempelaars E, Hensen M, Becher J. Lower limb strength training in children with cerebral palsy – a randomized controlled trial protocol for functional strength training based on progressive resistance exercise principles. BMC Pediatr. 2008;8(1):1–11. doi:10.1186/1471-2431-8-41.
   PubMedGoogle Scholar
• McBurney H, Taylor NF, Dodd KJ, Graham H. A qualitative analysis of the benefits of strength training for young people with cerebral palsy. Dev Med Child Neurol. 2003;45(10):658–63. doi:10.1111/j.1469-8749.2003.tb00867.x.
   PubMed Web of Science ®Google Scholar
• Gallinger TL, Fletcher JR, MacIntosh BR. Mechanisms of reduced plantarflexor function in Cerebral palsy: smaller triceps surae moment arm and reduced muscle force. J Biomech. 2020;110:109959. doi:10.1016/j.jbiomech.2020.109959.
   PubMed Web of Science ®Google Scholar
• Geertsen SS, Kirk H, Nielsen JB. Impaired ability to suppress excitability of antagonist motoneurons at onset of dorsiflexion in adults with cerebral palsy. Neural Plast. 2018;2018:1–11. doi:10.1155/2018/1265143.
   Web of Science ®Google Scholar
• Willerslev-Olsen M, Petersen TH, Farmer SF, Nielsen JB. Gait training facilitates central drive to ankle dorsiflexors in children with cerebral palsy. Brain. 2015;138:589–603. doi:10.1093/brain/awu399.
   PubMed Web of Science ®Google Scholar
• Oeffinger D, Bagley A, Rogers S, Gorton G, Kryscio R, Abel M, Damiano D, Barnes D, Tylkowski C. Outcome tools used for ambulatory children with cerebral palsy: responsiveness and minimum clinically important differences. Dev Med Child Neurol. 2008;50(12):918–25. doi:10.1111/j.1469-8749.2008.03150.x.
   PubMed Web of Science ®Google Scholar
• Damiano DL. Progressive resistance exercise increases strength but does not improve objective measures of mobility in young people with cerebral palsy. J Physiother. 2014;60(1):58. doi:10.1016/j.jphys.2013.12.010.
   PubMed Web of Science ®Google Scholar
• MacPhail HEA, Kramer JF. Effect of Isokinetic strength‐training on functional ability and walking efficiency in adolescents with cerebral palsy. Dev Med Child Neurol. 1995;37(9):763–75. doi:10.1111/j.1469-8749.1995.tb12060.x.
   PubMed Web of Science ®Google Scholar
• Park EY, Kim WH. Meta-analysis of the effect of strengthening interventions in individuals with cerebral palsy. Res Dev Disabil. 2014;35(2):239–49. doi:10.1016/j.ridd.2013.10.021.
   PubMed Web of Science ®Google Scholar
• Woollacott MH, Shumway-Cook A. Postural dysfunction during standing and walking in children with cerebral palsy: what are the underlying problems and what new therapies might improve balance? Neural Plast. 2005;12(2–3):211–19. doi:10.1155/NP.2005.211.
   PubMedGoogle Scholar
• Nashner LM, Shumway-Cook A, Marin O. Stance posture control in select groups of children with cerebral palsy: deficits in sensory organization and muscular coordination. Exp Brain Res. 1983;49(3):393–409. doi:10.1007/BF00238781.
   PubMed Web of Science ®Google Scholar
• de AC Duarte N, Grecco LAC, Franco RC, Zanon N, Oliveira CS. Correlation between pediatric balance scale and functional test in children with cerebral palsy. J Phys Ther Sci. 2014;26(6):849–53. doi:10.1589/jpts.26.849.
   PubMedGoogle Scholar
• Saquetto M, Carvalho V, Silva C, Conceição C, Gomes-Neto M. The effects of whole body vibration on mobility and balance in children with cerebral palsy: a systematic review with meta-analysis. J Musculoskelet Neuronal Interact. 2015;15:137–44.
   PubMed Web of Science ®Google Scholar
• Gillett JG, Lichtwark GA, Boyd RN, Barber LA. Functional anaerobic and strength training in young adults with cerebral palsy. Med Sci Sports Exerc. 2018;50(8):1549–57. doi:10.1249/MSS.0000000000001614.
   PubMed Web of Science ®Google Scholar