Cancer Related to Herbs and Dietary Supplements: Online Table of Case Reports. Part 5 of 5

References

• Abbott PJ. Comfrey: assessing the low-dose health risk. Med J Aust. 1988;149(11–12):678–682.
   Google Scholar
• Abnet CC. Carcinogenic food contaminants. Cancer Invest. 2007;25(3):189–196.
   Google Scholar
• Alonso-Amelot ME, Avendaño M. Possible association between gastric cancer and bracken fern in Venezuela: an epidemiologic study. Int J Cancer 2001;91:252–259.
   Google Scholar
• Alonso-Amelot ME, Avendaño M. Human carcinogenesis and bracken fern: a review of the evidence. Curr Med Chem. 2002;9(6):675–686.
   Google Scholar
• Alscher DM, Klotz U. Drug interaction of herbal tea containing St. John's wort with cyclosporine. Transpl Int. 2003;16(7):543–544.
   Google Scholar
• American Institute for Cancer Research. CUP: Continuous Update Project. http://www.aicr.org/continuous-update-project/. Accessed May 2, 2017.
   Google Scholar
• Anand P, Kunnumakkara AB, Sundaram C, Harikumar KB, Tharakan ST, Lai OS, et al. Cancer is a preventable disease that requires major lifestyle changes. Pharm Res. 2008;25(9):2097–2116.
   Google Scholar
• Baliga MS, Katiyar SK. Chemoprevention of photocarcinogenesis by selected dietary botanicals. Photochem Photobiol Sci. 2006;5(2):243–253.
   Google Scholar
• Behl M, Nyska A, Chhabra RS, Travlos GS, Fomby LM, Sparrow BR, et al. Liver toxicity and carcinogenicity in F344/N rats and B6C3F1 mice exposed to kava kava. Food Chem Toxicol. 2011;49(11):2820–2829.
   Google Scholar
• Béliveau R, Gingras D. Role of nutrition in preventing cancer. Can Fam Physician. 2007;53(11):1905–1911.
   Google Scholar
• Blackadar CB. Historical review of the causes of cancer. World J Clin Oncol. 2016;7(1):54–86.
   Google Scholar
• Blumenthal M, Busse WR, Godberg A, Gruenwald J, Hall T, Riggins W, Rister RS. The Complete German Commission E Monographs. Therapeutic Guide to Herbal Medicines. American Botanical Council, Austin, Texas; 1998.
   Google Scholar
• Boberg EW, Miller EC, Miller JA, Poland A, Liem A. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver. Cancer Res. 1983;43(11):5163–5173.
   Google Scholar
• Bode AM, Dong Z. Toxic phytochemicals and their potential risks for human cancer. Cancer Prev Res (Phila). 2015;8(1):1–8.
   Google Scholar
• Boh B. Ganoderma lucidum: a potential for biotechnological production of anti-cancer and immunomodulatory drugs. Recent Pat Anticancer Drug Discov. 2013;8(3):255–287.
   Google Scholar
• Borchert P, Miller JA, Miller EC, Shires TK. 1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse. Cancer Res. 1973;33(3):590–600.
   Google Scholar
• Boudreau MD, Beland FA, Nichols JA, Pogribna M. Toxicology and carcinogenesis studies of a nondecolorized [corrected] whole leaf extract of Aloe barbadensis Miller (Aloe vera) in F344/N rats and B6C3F1 mice (drinking water study). Natl Toxicol Program Tech Rep Ser. 2013;(577):1–266.
   Google Scholar
• Boudreau MD, Mellick PW, Olson GR, Felton RP, Thorn BT, Beland FA. Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis Miller (aloe vera) in F344/N rats. Toxicol Sci. 2013;131(1):26–39.
   Google Scholar
• Brown, AC. An overview of herb and dietary supplement efficacy, safety, and government regulation in the United States with suggested improvements. Part 1 of 5 series. Food Chem Toxicol. 2017a;107(Pt A):449–471.
   Google Scholar
• Brown AC. Liver toxicity related to herb and dietary supplements: online table of medical case reports. Part 2 of 5 series. Food Chem Toxicol. 2017b;107(Pt A):472–501.
   Google Scholar
• Brown AC. Kidney toxicity related to herb and dietary supplements: online table of medical case reports. Part 3 of 5 series. Food Chem Toxicol 2017c;107(Pt A):502–519.
   Google Scholar
• Brown AC. Heart toxicity related to herb and dietary supplements: online table of medical case reports. Part 4 of 5 series. J Diet Supp. 2017 (in press).
   Google Scholar
• Brown AC, Onopa J, Holck P, Kaufusi P, Kabasawa D, Craig WJ, et al. Traditional kava beverage consumption and liver function tests in a predominantly Tongan population in Hawaii. Clin Toxicol (Phila). 2007;45(5):549–556.
   Google Scholar
• Casari I, Falasca M. Diet and pancreatic cancer prevention. Cancers (Basel). 2015;7(4):2309–2317.
   Google Scholar
• Castellsagué X, Muñoz N, De Stefani E, Victora CG, Castelletto R, Rolón PA. Influence of maté drinking, hot beverages and diet on esophageal cancer risk in South America. Int J Cancer. 2000;88(4):658–664.
   Google Scholar
• Chan JM, Wang F, Holly EA. Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area. Cancer Epidemiol Biomarkers Prev. 2005;14:2093–2097.
   Google Scholar
• Chan PC, Rider CV, Nyska A, Bishop JB, Chhabra RS, Cora MC, et al. National Toxicology Program. Toxicology and carcinogenesis studies of Ginkgo biloba extract (CAS No. 90045-36-6) in F344/N rats and B6C3F1/N mice (Gavage studies). Natl Toxicol Program Tech Rep Ser. 2013;(578):1–183.
   Google Scholar
• Chen CH, Dickman KG, Huang CY, Moriya M, Shun CT, Tai HC, et al. Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes. Int J Cancer. 2013;133(1):14–20.
   Google Scholar
• Chen CH, Dickman KG, Moriya M, Zavadil J, Sidorenko VS, Edwards KL, et al. Aristolochic acid-associated urothelial cancer in Taiwan. Proc Natl Acad Sci U S A. 2012;109(21):8241–8246.
   Google Scholar
• Chi F, Wu R, Zeng YC, Xing R, Liu Y, Xu ZG. Post-diagnosis soy food intake and breast cancer survival: a meta-analysis of cohort studies. Asian Pac J Cancer Prev. 2013;14(4):2407–2412.
   Google Scholar
• Clauson-Kaas F, Jensen PH, Jacobsen OS, Juhler RK, Hansen HC. The naturally occurring carcinogen ptaquiloside is present in groundwater below bracken vegetation. Environ Toxicol Chem. 2014;33(5):1030–1034.
   Google Scholar
• Cosyns JP. Aristolochic acid and Chinese herbs nephropathy: a review of the evidence to date. Drug Saf. 2003;26(1):33–48.
   Google Scholar
• Cosyns JP, Goebbels RM, Liberton V, Schmeiser HH, Bieler CA, Bernard AM. Chinese herbs nephropathy-associated slimming regimen induces tumours in the fore stomach but no interstitial nephropathy in rats. Arch Toxicol. 1998;72(11):738–743.
   Google Scholar
• Cosyns JP, Jadoul M, Squifflet JP, Wese FX, van Ypersele de Strihou C. Urothelial lesions in Chinese-herb nephropathy. Am J Kidney Dis. 1999;33(6):1011–1017.
   Google Scholar
• Dasanayake AP, Silverman AJ, Warnakulasuriya S. Maté drinking and oral and oro-pharyngeal cancer: a systematic review and meta-analysis. Oral Oncol. 2010;46(2):82–86.
   Google Scholar
• Debelle FD, Vanherweghem JL, Nortier JL. Aristolochic acid nephropathy: a worldwide problem. Kidney Int. 2008;74(2):158–169.
   Google Scholar
• Deneo-Pellegrini H, De Stefani E, Boffetta P, Ronco AL, Acosta G, Correa P, et al. Maté consumption and risk of oral cancer: case-control study in Uruguay. Head Neck. 2013;35(8):1091–1095.
   Google Scholar
• De Ruyck K, De Boevre M, Huybrechts, De Saeger S. Dietary mycotoxins, co-exposure, and carcinogenesis in humans: short review. Mutat Res Rev Mutat Res. 2015;766:32–41.
   Google Scholar
• De Stefani E, Correa P, Fierro L, Fontham E, Chen V, Zavala D. Black tobacco, maté, and bladder cancer. A case-control study from Uruguay. Cancer. 1991;67(2):536–540.
   Google Scholar
• De Stefani E, Deneo-Pellegrini H, Ronco AL, Boffetta P, Correa P, Mendilaharsu M, et al. Diet patterns and risk of squamous cell oesophageal carcinoma: a case-control study in Uruguay. Asian Pac J Cancer Prev. 2014;15(6):2765–2769.
   Google Scholar
• De Stefani E, Fierro L, Mendilaharsu M, Ronco A, Larrinaga MT, Balbi JC, et al. Meat intake, ‘maté’ drinking and renal cell cancer in Uruguay: a case-control study. Br J Cancer. 1998;78(9):1239–1243.
   Google Scholar
• De Stefani E, Boffetta P, Deneo-Pellegrini H, Correa P, Ronco AL, Brennan P, et al. Non-alcoholic beverages and risk of bladder cancer in Uruguay. BMC Cancer. 2007;7:57.
   Google Scholar
• Dufay S, Worsley A, Monteillier A, Avanzi C, Sy J, Ng TF, et al. Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro. J Pharm Pharmacol. 2014;66(10):1478–1490.
   Google Scholar
• Dunnick JK, Nyska A. The toxicity and pathology of selected dietary herbal medicines. Toxicol Pathol. 2013;41(2):374–386.
   Google Scholar
• Ernst E. Adulteration of Chinese herbal medicines with synthetic drugs: a systematic review. J Intern Med. 2002;252(2):107–113.
   Google Scholar
• Evans IA, Jones RS, Mainwaring-Burton R. Passage of bracken fern toxicity into milk. Nature 1972;237:107–108.
   Google Scholar
• Evans IA, Widdop B, Jones RS, Barber GD, Leach H, Jones DL, et al. The possible human hazard of the naturally occurring bracken carcinogen. Biochem J. 1971;124(2):29P–30P.
   Google Scholar
• Fang X, Wei J, He X, An P, Wang H, Jiang L, Shao D, Liang H, Li Y, Wang F, Min J. Landscape of dietary factors associated with risk of gastric cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. Eur J Cancer. 2015;51(18):2820–2832.
   Google Scholar
• FDA. Aristolochic acid: letter to industry associations regarding safety concerns related to the use of botanical products containing aristolochic acid. http://www.fda.gov/Food/RecallsOutbreaksEmergencies/SafetyAlertsAdvisories/ucm096374.htm. Published April 9, 2001a. Accessed May 2, 2017.
   Google Scholar
• FDA. Aristolochic acid: listing of botanical ingredients of concern. http://www.fda.gov/Food/RecallsOutbreaksEmergencies/SafetyAlertsAdvisories/ucm095283.htm. Published April 9, 2001b. Accessed May 1, 2017.
   Google Scholar
• FDA. FDA advises dietary supplement manufacturers to remove comfrey products from the market. http://www.fda.gov/Food/RecallsOutbreaksEmergencies/SafetyAlertsAdvisories/ucm111219.htm. Published July 6, 2001c. Accessed May 2, 2017.
   Google Scholar
• FDA. Poisonous plant database. https://www.accessdata.fda.gov/scripts/plantox/textResults.cfm. Updated May 2008. Accessed May 2, 2017.
   Google Scholar
• FDA. Safety. Kava (Piper methysticum). https://wayback.archive-it.org/7993/20170112171412/http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm154577.htm. Updated August 20, 2013. Accessed May 2, 2017.
   Google Scholar
• FDA. Code of Federal Regulations. Title 21, Volume 3. PART 189—Substances Prohibited from Use in Human Food. Subpart C—Substances Generally Prohibited from Direct Addition or Use as Human Food. Sec. 189.180 Safrole. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm?fr=189.180. Updated September 21, 2016. Accessed May 2, 2017.
   Google Scholar
  Foote J, Cohen B. Medicinal herb use and the renal patient. J Ren Nutr 1998;8(1):40–42.
   Google Scholar
• Fox DW, Hart MC, Bergeson PS, Jarrett PB, Stillman AE, Huxtable RJ. Pyrrolizidine (Senecio) intoxication mimicking Reye syndrome. J Pediatr. 1978;93(6):980–982.
   Google Scholar
• Freedman ND, Park Y, Subar AF, Hollenbeck AR, Leitzmann MF, Schatzkin A, et al. Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study. Int J Cancer. 2008;122:2330–2336.
   Google Scholar
• Galpin OP, Whitaker CJ, Whitaker R, Kassab JY. Gastric cancer in Gwynedd. Possible links with bracken. Br J Cancer. 1990;61:737–740.
   Google Scholar
• Ghadirian P. Thermal irritation and esophageal cancer in northern Iran. Cancer. 1987;60(8):1909–1914.
   Google Scholar
• Ghadirian P, Vobecky J, Vobecky JS. Factors associated with cancer of the oesophagus: an overview. Cancer Detect Prev. 1988;11(3–6):225–234.
   Google Scholar
• Goldenberg D. Maté: a risk factor for oral and oropharyngeal cancer. Oral Oncol. 2002;38(7):646–649.
   Google Scholar
• Goldenberg D, Golz A, Joachims HZ. The beverage maté: a risk factor for cancer of the head and neck. Head Neck. 2003;25(7):595–601.
   Google Scholar
• Grollman AP. Aristolochic acid nephropathy: harbinger of a global iatrogenic disease. Environ Mol Mutagen. 2013;54(1):1–7.
   Google Scholar
• Gruenwald J, Brendler T, Jaenicke C (Eds). PDR for herbal medicines. Montvale, NJ: Thomson Healthcare, 2007.
   Google Scholar
• Guh JY, Chen HC, Tsai JF, Chuang LY. Herbal therapy is associated with the risk of CKD in adults not using analgesics in Taiwan. Am J Kidney Dis. 2007;49(5):626–633.
   Google Scholar
• Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 2006;7(1):79–88.
   Google Scholar
• Haines JD Jr. Sassafras tea and diaphoresis. Postgrad Med. 1991;90(4):75–76.
   Google Scholar
• Haller C, Kearney T, Bent S, Ko R, Benowitz N, Olson K. Dietary supplement adverse events: report of a one-source poison center surveillance project. J Med Toxicol. 2008;4(2):84–92.
   Google Scholar
• Harris PN, Chen KK. Development of hepatic tumors in rats following ingestion of Senecio longilobus. Cancer Res. 1970;30(12):2881–2886.
   Google Scholar
• Helferich WG, Andrade JE, Hoagland MS. Phytoestrogens and breast cancer: a complex story. Inflammopharmacology. 2008;16(5):219–226.
   Google Scholar
• Hirono I, Mori H, Culvenor CC. Carcinogenic activity of coltsfoot, Tussilago farfara l. 1976;67(1):125–129.
   Google Scholar
• Hirono I, Mori H, Haga M. Carcinogenic activity of Symphytum officinale. J Natl Cancer Inst. 1978;61(3):865–869.
   Google Scholar
• Hirono I, Shimizu M, Fushimi K, Mori H, Kato K. Carcinogenic activity of Petasites japonicus Maxim., a kind of coltsfoot. 1973;64(5):527–528.
   Google Scholar
• Hoenerhoff MJ, Pandiri AR, Snyder SA, Hong HH, Ton TV, Peddada S, et al. Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two sources differ from spontaneous liver tumors in cancer gene mutations and genomic pathways. Toxicol Pathol. 2013;41(6):826–841.
   Google Scholar
• Hsieh SC, Lai JN, Chen PC, Chen CC, Chen HJ, Wang JD. Is Duhuo Jisheng Tang containing Xixin safe? A four-week safety study. Chin Med. 2010;5(1):6.
   Google Scholar
• IARC. Bracken fern. IARC Monographs. 1987;Supp7:135–136. http://monographs.iarc.fr/ENG/Monographs/suppl7/Suppl7-34.pdf.
   Google Scholar
• IARC. Maté. IARC Monographs. 1991;51:273–287. http://monographs.iarc.fr/ENG/Monographs/vol51/mono51-9.pdf.
   Google Scholar
• IARC. Aristolochia species and aristolochic acids. IARC Monographs. 2002a;82:69–128. http://monographs.iarc.fr/ENG/Monographs/vol82/mono82-6B.pdf.
   Google Scholar
• IARC. C. Rubia tinctorum, morida officinalis and anthraquinones. IARC Monographs. 2002b;82:129–151. http://monographs.iarc.fr/ENG/Monographs/vol82/index.php.
   Google Scholar
• IARC. Senecio species and riddelliine. IARC Monographs. 2002c;82:153–168. http://monographs.iarc.fr/ENG/Monographs/vol82/mono82-6D.pdf.
   Google Scholar
• IARC. Plants containing aristolochic acid. IARC Monographs. 2012;100A:347–362. http://monographs.iarc.fr/ENG/Monographs/vol100A/mono100A-23.pdf.
   Google Scholar
• IARC. Some drugs and herbal products. IARC Monographs. 2016;108. http://monographs.iarc.fr/ENG/Monographs/vol108/index.php.
   Google Scholar
• IARC. List of IARC monographs. http://monographs.iarc.fr/ENG/Publications/List-of-Volumes.pdf. Accessed May 2, 2017.
   Google Scholar
• Inoue K, Yoshida M, Takahashi M, Fujimoto H, Shibutani M, Hirose M, et al. Carcinogenic potential of alizarin and rubiadin, components of madder color, in a rat medium-term multi-organ bioassay. Cancer Sci. 2009;100(12):2261–2267.
   Google Scholar
• Islami F, Boffetta P, Ren JS, Pedoeim L, Khatib D, Kamangar F. High-temperature beverages and foods and esophageal cancer risk—a systematic review. Int J Cancer. 2009;125(3):491–524.
   Google Scholar
• Ju YH, Doerge DR, Helferich WG. A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food Chem Toxicol. 2008;46(1):310–320.
   Google Scholar
• Kampan NC, Madondo MT, McNally OM, Quinn M, Plebanski M. Paclitaxel and its evolving role in the management of ovarian cancer. Biomed Res Int. 2015;2015:413076.
   Google Scholar
• Kanaan N, Hassoun Z, Raggi C, Jadoul M, Mourad M, De Meyer M, Aydin S, et al. Long-term Outcome of Kidney Recipients Transplanted for Aristolochic Acid Nephropathy. Transplantation. 2016;100(2):416–21.
   Google Scholar
• Kinjo J, Nakano D, Fujioka T, Okabe H. Screening of promising chemotherapeutic candidates from plants extracts. J Nat Med. 2016;70(3):335–360.
   Google Scholar
• Kooti W, Servatyari K, Behzadifar M, Asadi-Samani M, Sadeghi F, Nouri B, Zare Marzouni H. Effective medicinal plant in cancer treatment, Part 2 [published online ahead of print January 1, 2017]. J Evid Based Complement Altern Med. doi:10.1177/2156587217696927.
   Google Scholar
• Kwan LP, Mok MM, Ma MK, Lam MF. Acute drug toxicity related to drinking herbal tea in a kidney transplant recipient. Ren Fail. 2014;36(2):309–312.
   Google Scholar
• Lai MN, Lai JN, Chen PC, Hsieh SC, Hu FC, Wang JD. Risks of kidney failure associated with consumption of herbal products containing Mu Tong or Fangchi: a population-based case-control study. Am J Kidney Dis. 2010;55(3):507–518.
   Google Scholar
• Lemy A, Wissing KM, Rorive S, Zlotta A, Roumeguere T, Muniz Martinez MC, et al. Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: a case series with 15-source follow-up. Am J Kidney Dis. 2008;51(3):471–477.
   Google Scholar
• Li XZ, Ramzan I. Role of ethanol in kava hepatotoxicity. Phytother Res. 2010;24(4):475–480.
   Google Scholar
• Lipsky MM, Hinton DE, Klaunig JE, Trump BF. Biology of hepatocellular neoplasia in the mouse. I. Histogenesis of safrole-induced hepatocellular carcinoma. J Natl Cancer Inst. 1981;67(2):365–376.
   Google Scholar
• Liu RH. Health-promoting components of fruits and vegetables in the diet. Adv Nutr. 2013;4(3):384S–92S.
   Google Scholar
• Loria D, Barrios E, Zanetti R. Cancer and yerba maté consumption: a review of possible associations. Rev Panam Salud Publica. 2009;25(6):530–539.
   Google Scholar
• Magee PJ, Rowland I. Soy products in the management of breast cancer. Curr Opin Clin Nutr Metab Care. 2012;15(6):586–591.
   Google Scholar
• Manteiga R, Park DL, Ali SS. Risks associated with consumption of herbal teas. Rev Environ Contam Toxicol. 1997;150:1–30.
   Google Scholar
• Marcus DM, Grollman AP. Botanical medicines—the need for new regulations. N Engl J Med. 2002;347(25):2073–2076.
   Google Scholar
• Mathijssen RH, Verweij J, de Bruijn P, Loos WJ, Sparreboom A. Effects of St. John's wort on irinotecan metabolism. J Natl Cancer Inst. 2002;94(16):1247–1249.
   Google Scholar
• Mei N, Guo L, Fu PP, Heflich RH, Chen T. Mutagenicity of comfrey (Symphytum officinale) in rat liver. Br J Cancer. 2005;92(5):873–875.
   Google Scholar
• Mei N, Guo L, Zhang L, Shi L, Sun YA, Fung C, et al. Herb-drug interactions in oncology: focus on mechanisms of induction. Oncologist. 2006;11(7):742–752.
   Google Scholar
• Muñoz N, Victora CG, Crespi M, Saul C, Braga NM, Correa P. Hot maté drinking and precancerous lesions of the oesophagus: an endoscopic survey in southern Brazil. Int J Cancer. 1987;39(6):708–709.
   Google Scholar
• National Toxicology Program. Toxicology and carcinogenesis studies of goldenseal root powder (Hydrastis canadensis) in F344/N rats and B6C3F1 mice (feed studies). Natl Toxicol Program Tech Rep Ser. 2010;(562):1–188.
   Google Scholar
• National Toxicology Program. Toxicology and carcinogenesis studies of kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser. 2012;(571):1–186.
   Google Scholar
• Neergheen-Bhujun VS. Underestimating the toxicological challenges associated with the use of herbal medicinal products in developing countries. Biomed Res Int. 2013;2013:804086.
   Google Scholar
• Newman DJ, Cragg GM. Natural products as sources of new drugs over the 30 sources from 1981 to 2010. J Nat Prod. 2012;75(3):311–335.
   Google Scholar
• Nortier JL, Martinez MC, Schmeiser HH, Arlt VM, Bieler CA, Petein M, et al. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). N Engl J Med 2000;342(23):1686–1692.
   Google Scholar
• Nortier JL, Vanherweghem JL. Renal interstitial fibrosis and urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi) Toxicology. 2002;181–182:577–580.
   Google Scholar
• Nowack R, Nowak B. Herbal teas interfere with cyclosporin levels in renal transplant patients. Nephrol Dial Transplant. 2005;20(11):2554–2556.
   Google Scholar
• Ortiz Cansado A, Crespo Valadés E, Morales Blanco P, Sáenz de Santamaría J, González Campillejo JM, Ruiz Téllez T. [Veno-occlusive liver disease due to intake of Senecio vulgaris tea]. Gastroenterol Hepatol. 1995;18(8):413–416.
   Google Scholar
• Palmer S. Diet, nutrition, and cancer. Prog Food Nutr Sci. 1985;9(3–4):283–341.
   Google Scholar
• Pandey S, Shaw PN, Hewavitharana AK. Review of procedures used for the extraction of anti-cancer compounds from tropical plants. Anticancer Agents Med Chem. 2015;15(3):314–326.
   Google Scholar
• Pandiri AR, Sills RC, Hoenerhoff MJ, Peddada SD, Ton TV, Hong HH, et al. Aloe vera non-decolorized whole leaf extract-induced large intestinal tumors in F344 rats share similar molecular pathways with human sporadic colorectal tumors. Toxicol Pathol. 2011;39(7):1065–1074.
   Google Scholar
• Perla V, Jayanty SS. Biguanide related compounds in traditional antidiabetic functional foods. Food Chem. 2013;138(2–3):1574–1580.
   Google Scholar
• Pintos J, Franco EL, Oliveira BV, Kowalski LP, Curado MP, Dewar R. Maté, coffee, and tea consumption and risk of cancers of the upper aerodigestive tract in southern Brazil. Epidemiology. 1994;5(6):583–590.
   Google Scholar
• Rates SM. Plants as source of drugs. Toxicon. 2001;39(5):603–613.
   Google Scholar
• Reuber MD. Neoplasms of the forestomach in mice ingesting dihydrosafrole. Digestion. 1979;19(1):42–47.
   Google Scholar
• Ruschitzka F, Meier PJ, Turina M, Lüscher TF, Noll G. Acute heart transplant rejection due to Saint John's wort. Lancet. 2000;355(9203):548–549.
   Google Scholar
• Russo M, Russo GL, Daglia M, Kasi PD, Ravi S, Nabavi SF, et al. Understanding genistein in cancer: the “good” and the “bad” effects: a review. Food Chem. 2016;196:589–600.
   Google Scholar
• Schiff PL Jr, Srinivasan VS, Giancaspro GI, Roll DB, Salguero J, Sharaf MH. The development of USP botanical dietary supplement monographs, 1995–2005. J Nat Prod. 2006;69(3):464–472.
   Google Scholar
• Seawright AA. Directly toxic effects of plant chemicals which may occur in human and animal foods. Nat Toxins 1995;3:227–32; discussion 42.
   Google Scholar
• Sewram V, De Stefani E, Brennan P, Boffetta P. Maté consumption and the risk of squamous cell esophageal cancer in Uruguay. Cancer Epidemiol Biomarkers Prev. 2003;12(6):508–513.
   Google Scholar
• Spagnuolo C, Russo GL, Orhan IE, Habtemariam S, Daglia M, Sureda A, et al. Genistein and cancer: current status, challenges, and future directions. Adv Nutr. 2015;6(4):408–419.
   Google Scholar
• Stefani ED, Moore M, Aune D, Deneo-Pellegrini H, Ronco AL, Boffetta P, et al. Maté consumption and risk of cancer: a multi-site case-control study in Uruguay. Asian Pac J Cancer Prev. 2011;12(4):1089–1093.
   Google Scholar
• Stefanovic V, Toncheva D, Polenakovic M. Balkan nephropathy. Clin Nephrol. 2015;83(7 Suppl 1):64–69.
   Google Scholar
• Stickel F, Patsenker E, Schuppan D. Herbal hepatotoxicity. J Hepatol. 2005;43(5):901–910.
   Google Scholar
• Stillman AE, Huxtable RJ, Fox D, Hart M, Bergeson P. Pyrrolizidine (Senecio) poisoning in Arizona: severe liver damage due to herbal teas. Ariz Med. 1977;34(8):545–546.
   Google Scholar
• Sweet ES, Standish LJ, Goff BA, Andersen MR. Adverse events associated with complementary and alternative medicine use in ovarian cancer patients. Integr Cancer Ther. 2013;12(6):508–516.
   Google Scholar
• Toth B. Carcinogenic fungal hydrazines. In Vivo. 1991;5(2):95–100.
   Google Scholar
• Triolet J, Shaik AA, Gallaher DD, O'Sullivan MG, Xing C. Reduction in colon cancer risk by consumption of kava or kava fractions in carcinogen-treated rats. Nutr Cancer. 2012;64(6):838–846.
   Google Scholar
• Turati F, Rossi M, Pelucchi C, Levi F, La Vecchia C. Fruit and vegetables and cancer risk: a review of southern European studies. Br J Nutr. 2015;113(Suppl 2):S102–S110.
   Google Scholar
• Vaclavik L, Krynitsky AJ, Rader JI. Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography-multistage fragmentation mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(5):784–791.
   Google Scholar
• van Duijnhoven FJ, Bueno-De-Mesquita HB, Ferrari P, Jenab M, Boshuizen HC, Ros MM, et al. Fruit, vegetables, and colorectal cancer risk: the European prospective investigation into cancer and nutrition. Am J Clin Nutr. 2009;89:1441–1452.
   Google Scholar
• Vanherweghem JL. Misuse of herbal remedies: the case of an outbreak of terminal renal failure in Belgium. J Altern Complement Med 1998;4(1):15–16.
   Google Scholar
• Vanherweghem JL, Tielemans C, Simon J, Depierreux M. Chinese herbs nephropathy and renal pelvic carcinoma. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association. Nephrol Dial Transplant. 1995;10(2):270–273.
   Google Scholar
• Vassallo A, Correa P, De Stéfani E, Cendán M, Zavala D, Chen V, et al. Esophageal cancer in Uruguay: a case-control study. J Natl Cancer Inst. 1985;75(6):1005–1009.
   Google Scholar
• Velicer CM, Ulrich CM. Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review. J Clin Oncol. 2008;26(4):665–673.
   Google Scholar
• Vesselinovitch SD, Rao KV, Mihailovich N. Transplacental and lactational carcinogenesis by safrole. Cancer Res. 1979;39(11):4378–4380.
   Google Scholar
• Vilar JH, García M, Cabrera P. [Veno-occlusive liver disease induced by Senecio vulgaris toxicity]. Gastroenterol Hepatol. 2000;23(6):285–286.
   Google Scholar
• Westendorf J, Pfau W, Schulte A. Carcinogenicity and DNA adduct formation observed in ACI rats after long-term treatment with madder root, Rubia tinctorum L. Carcinogenesis. 1998;19(12):2163–2168.
   Google Scholar
• Wiedenfeld H. Plants containing pyrrolizidine alkaloids: toxicity and problems. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011;28(3):282–292.
   Google Scholar
• Wu F, Groopman JD, Pestka JJ. Public health impacts of foodborne mycotoxins. Annu Rev Food Sci Technol. 2014;5:351–372.
   Google Scholar
• Xu T, Beelman RB, Lambert JD. The cancer preventive effects of edible mushrooms. Anticancer Agents Med Chem. 2012;12(10):1255–1263.
   Google Scholar
• Yamani A, Bunel V, Antoine MH, Husson C, Stévigny C, Duez P, et al. Substitution between Aristolochia and Bryonia genus in North-Eastern Morocco: toxicological implications. J Ethnopharmacol. 2015;166:250–260.
   Google Scholar
• Yang CS, Lin CH, Chang SH, Hsu HC. Rapidly progressive fibrosing interstitial nephritis associated with Chinese herbal drugs. Am J Kidney Dis 2000;35(2):313–318.
   Google Scholar
• Yang HY, Chen PC, Wang JD. Chinese herbs containing aristolochic acid associated with renal failure and urothelial carcinoma: a review from epidemiologic observations to causal inference. Biomed Res Int. 2014;2014:569325.
   Google Scholar
• Yokohira M, Yamakawa K, Hosokawa K, Matsuda Y, Kuno T, Saoo K, et al. Promotion potential of madder color in a medium-term multi-organ carcinogenesis bioassay model in F344 rats. J Food Sci. 2008;73(3):T26–T32.
   Google Scholar
• Yuie-Zhong S. Recent natural products based drug development: a pharmaceutical industry perspective. J Nat Prod. 1998;61:1053–1071.
   Google Scholar
• Zhou J, Ouedraogo M, Qu F, Duez P. Potential genotoxicity of traditional Chinese medicinal plants and phytochemicals: an overview. Phytother Res. 2013;27(12):1745–1755.
   Google Scholar