5,729
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Subjective assessment of the effects of an herbal supplement containing lavender essential oil on sleep quality: A randomized, double-blind, placebo-controlled crossover study

ORCID Icon, , , , ORCID Icon & | (Reviewing Editor) show all
Article: 1380871 | Received 10 Mar 2017, Accepted 06 Sep 2017, Published online: 03 Nov 2017

References

  • Akhondzadeh, S., Kashani, L., Fotouhi, A., Jarvandi, S., Mobaseri, M., Moin, M., & Taghizadeh, M. (2003). Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: A double-blind, randomized trial. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 27, 123–127. doi:10.1016/S0278-5846(02)00342-1
  • Atanassova-Shopova, S., & Roussinov, K. S. (1969). On certain central neurotropic effects of lavender essential oil. Izvestiia Na Instituta Po Fiziologiia, 13, 69–77.
  • Baldinger, P., Höflich, A. S., Mitterhauser, M., Hahn, A., Rami-Mark, C., Spies, M., & Kasper, S. (2015). Effects of Silexan on the serotonin-1A receptor and microstructure of the human brain: A randomized, placebo-controlled, double-blind, cross-over study with molecular and structural neuroimaging. The International Journal of Neuropsychopharmacology, 18, pyu063. doi:10.1093/ijnp/pyu063
  • Barocelli, E., Calcina, F., Chiavarini, M., Impicciatore, M., Bruni, R., Bianchi, A., & Ballabeni, V. (2004). Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon “Grosso” essential oil. Life Sciences, 76, 213–223. doi:10.1016/j.lfs.2004.08.008
  • Bradley, B. F., Brown, S. L., Chu, S., & Lea, R. W. (2009). Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips. Human Psychopharmacology, 24, 319–330. doi:10.1002/hup.1016
  • Brum, L. F., Elisabetsky, E., & Souza, D. (2001). Effects of linalool on [(3)H]MK801 and [(3)H] muscimol binding in mouse cortical membranes. Phytotherapy Research, 15, 422–425. doi:10.1002/ptr.973
  • Budhiraja, R., Roth, T., Hudgel, D. W., Budhiraja, P., & Drake, C. L. (2011). Prevalence and polysomnographic correlates of insomnia comorbid with medical disorders. Sleep, 34, 859–867. doi:10.5665/SLEEP.1114
  • Buysse, D. J. (2013). Insomnia. Journal of the American Medical Association, 309, 706–716. doi:10.1001/jama.2013.193
  • Cornu, C., Remontet, L., Noel-Baron, F., Nicolas, A., Feugier-Favier, N., Roy, P., & Kassaï, B. (2010). A dietary supplement to improve the quality of sleep: A randomized placebo controlled trial. BMC Complementary and Alternative Medicine, 10, 29. doi:10.1186/1472-6882-10-29
  • Dimpfel, W., Pischel, I., & Lehnfeld, R. (2004). Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volunteers. European Journal of Medical Research, 9, 423–431.
  • Elisabetsky, E., Marschner, J., & Souza, D. O. (1995). Effects of Linalool on glutamatergic system in the rat cerebral cortex. Neurochemical Research, 20, 461–465. doi:10.1007/BF00973103
  • Goel, N., & Grasso, D. J. (2004). Olfactory discrimination and transient mood change in young men and women: Variation by season, mood state, and time of day. Chronobiology International, 21, 691–719. doi:10.1081/CBI-200025989
  • Goel, N., Kim, H., & Lao, R. P. (2005). An olfactory stimulus modifies nighttime sleep in young men and women. Chronobiology International, 22, 889–904. doi:10.1080/07420520500263276
  • Guimarães, A. G., Quintans, J. S. S., & Quintans-Júnior, L. J. (2013). Monoterpenes with analgesic activity–a systematic review. Phytotherapy Research, 27, 1–15. doi:10.1002/ptr.4686
  • Hawken, P. A. R., Fiol, C., & Blache, D. (2012). Genetic differences in temperament determine whether lavender oil alleviates or exacerbates anxiety in sheep. Physiology & Behavior, 105, 1117–1123. doi:10.1016/j.physbeh.2011.12.005
  • van Hees, V. T., Sabia, S., Anderson, K. N., Denton, S. J., Oliver, J., Catt, M., & Singh-Manoux, A. (2015). A novel, open access method to assess sleep duration using a wrist-worn accelerometer. PLoS One, 10, e0142533. doi:10.1371/journal.pone.0142533
  • Hongratanaworakit, T. (2011). Aroma-therapeutic effects of massage blended essential oils on humans. Natural Products Communications, 6, 1199–1204.
  • Imanishi, J., Kuriyama, H., Shigemori, I., Watanabe, S., Aihara, Y., Kita, M., & Fukui, K. (2009). Anxiolytic effect of aromatherapy massage in patients with breast cancer. Evidence-Based Complementary and Alternative Medicine, 6, 123–128. doi:10.1093/ecam/nem073
  • Jang, H. S., Jung, J. Y., Jang, I. S., Jang, K. H., Kim, S. H., Ha, J. H., & Lee, M. G. (2012). L-theanine partially counteracts caffeine-induced sleep disturbances in rats. Pharmacology, Biochemistry, and Behavior, 101, 217–221. doi:10.1016/j.pbb.2012.01.011
  • Kasper, S. (2013). An orally administered lavandula oil preparation (Silexan) for anxiety disorder and related conditions: An evidence based review. International Journal of Psychiatry in Clinical Practice, 17, 15–22. doi:10.3109/13651501.2013.813555
  • Kasper, S., Gastpar, M., Müller, W. E., Volz, H. P., Möller, H. J., Schläfke, S., & Dienel, A. (2014). Lavender oil preparation Silexan is effective in generalized anxiety disorder–a randomized, double-blind comparison to placebo and paroxetine. The International Journal of Neuropsychopharmacology, 17, 859–869. doi:10.1017/S1461145714000017
  • Koto, R., Imamura, M., Watanabe, C., Obayashi, S., Shiraishi, M., Sasaki, Y., & Azuma, H. (2006). Linalyl acetate as a major ingredient of lavender essential oil relaxes the rabbit vascular smooth muscle through dephosphorylation of myosin light chain. Journal of Cardiovascular Pharmacology, 48, 850–856. doi:10.1097/01.fjc.0000238589.00365.42
  • Kripke, D. F., Garfinkel, L., Wingard, D. L., Klauber, M. R., & Marler, M. R. (2002). Mortality associated with sleep duration and insomnia. Archives of General Psychiatry, 59, 131–136. doi:10.1001/archpsyc.59.2.131
  • Kuroda, K., Inoue, N., Ito, Y., Kubota, K., Sugimoto, A., Kakuda, T., & Fushiki, T. (2005). Sedative effects of the jasmine tea odor and (R)-(-)-linalool, one of its major odor components, on autonomic nerve activity and mood states. European Journal of Applied Physiology, 95, 107–114. doi:10.1007/s00421-005-1402-8
  • Lillehei, A. S., Halcón, L. L., Savik, K., & Reis, R. (2015). Effect of inhaled lavender and sleep hygiene on self-reported sleep issues: A randomized controlled trial. The Journal of Alternative and Complementary Medicine, 21, 430–438. doi:10.1089/acm.2014.0327
  • Linck, V. M., da Silva, A. L., Figueiró, M., Piato, A. L., Herrmann, A. P., Dupont Birck, F., & Elisabetsky, E. (2009). Inhaled linalool-induced sedation in mice. Phytomedicine, 16, 303–307. doi:10.1016/j.phymed.2008.08.001
  • Lyon, M. R., Kapoor, M. P., & Juneja, L. R. (2011). The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): A randomized, double-blind, placebo-controlled clinical trial. Alternative Medicine Review, 16, 348–354.
  • Ngan, A., & Conduit, R. (2011). A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytotherapy Research, 25, 1153–1159. doi:10.1002/ptr.3400
  • Ozeki, M., Juneja, L. R., & Shirakawa, S. (2008). A study of L-theanine and daytime drowsiness. Japanese Journal of Physiological Anthropology, 13, 9–15.
  • Peana, A. T., D’Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. L. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 9, 721–726. doi:10.1078/094471102321621322
  • Peana, A. T., De Montis, M. G., Nieddu, E., Spano, M. T., D’Aquila, P. S., & Pippia, P. (2004). Profile of spinal and supra-spinal antinociception of (-)-linalool. European Journal of Pharmacology, 485, 165–174. doi:10.1016/j.ejphar.2003.11.066
  • Peana, A. T., Marzocco, S., Popolo, A., & Pinto, A. (2006). (-)-Linalool inhibits in vitro NO formation: Probable involvement in the antinociceptive activity of this monoterpene compound. Life Sciences, 78, 719–723. doi:10.1016/j.lfs.2005.05.065
  • Rao, T. P., Ozeki, M., & Juneja, L. R. (2015). In search of a safe natural sleep aid. Journal of the American College Nutrition, 34, 436–447. doi:10.1080/07315724.2014.926153
  • Roth, T. (2009). Sleep duration, insomnia and longevity. Sleep Medicine, 10, 1071–1072. doi:10.1016/j.sleep.2009.04.004
  • Shahid, A., Wilkinson, K., Marcu, S., & Shapiro, C. M. (2011). Leeds sleep evaluation questionnaire (LSEQ). In A. Shahid, K. Wilkinson, S. Marcu, & C. M. Shapiro (Eds.), STOP, THAT and one hundred other sleep scales (pp. 211–213). New York: Springer. doi:10.1007/978-1-4419-9893-4_48
  • Sinclair, L., & Nutt, D. (2007). Anxiolytics. Psychiatry, 6, 284–288. doi:10.1016/j.mppsy.2007.04.007
  • Tanida, M., Niijima, A., Shen, J., Nakamura, T., & Nagai, K. (2006). Olfactory stimulation with scent of lavender oil affects autonomic neurotransmission and blood pressure in rats. Neuroscience Letters, 398, 155–160. doi:10.1016/j.neulet.2005.12.076
  • Tudor-Locke, C., Barreira, T. V., Schuna, J. M., Jr, Mire, E. F., & Katzmarzyk, P. T. (2014). Fully automated waist-worn accelerometer algorithm for detecting children’s sleep-period time separate from 24-h physical activity or sedentary behaviors. Applied Physiology, Nutrition, and Metabolism, 39, 53–57. doi:10.1139/apnm-2013-0173
  • Uehleke, B., Schaper, S., Dienel, A., Schlaefke, S., & Stange, R. (2012). Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine, 19, 665–671. doi:10.1016/j.phymed.2012.02.020
  • Woelk, H., & Schläfke, S. (2010). A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine, 17, 94–99. doi:10.1016/j.phymed.2009.10.006
  • Zick, S. M., Wright, B. D., Sen, A., & Arnedt, J. T. (2011). Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: A randomized placebo-controlled pilot study. BMC Complementary and Alternative Medicine, 11, 78. doi:10.1186/1472-6882-11-78
  • Zisapel, N., & Laudon, M. (2003). Subjective assessment of the effects of CNS-active drugs on sleep by the Leeds sleep evaluation questionnaire: A review. Human Psychopharmacology, 18, 1–20. doi:10.1002/hup.455
  • Zisapel, N., & Nir, T. (2003). Determination of the minimal clinically significant difference on a patient visual analog sleep quality scale. Journal of Sleep Research, 12, 291–298. doi:10.1046/j.0962-1105.2003.00365