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Toxicology Communications Volume 4, 2020 - Issue 1
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Case Report

New psychoactive substances (NPS) escape routine drug testing: a case report of phenibut

Torben Breindahla Department of Clinical Biochemistry, North Denmark Regional Hospital, Hjørring, Denmark; Correspondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8166-1983View further author information
ORCID Icon,
Peter Hinderssona Department of Clinical Biochemistry, North Denmark Regional Hospital, Hjørring, Denmark; View further author information
&
Andreas Kimergårdb National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UKORCID Iconhttps://orcid.org/0000-0002-2080-9865View further author information
ORCID Icon
Pages 55-58 | Published online: 22 Jul 2020

References

  • Regulation (EU) 2017/2101 of the European Parliament and of the Council of 15 November 2017 amending Regulation (EC) No 1920/2006 as regards information exchange on, and an early warning system and risk assessment procedure for, new psychoactive substances. 2017. Available from: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32017R2101
  • Europol & European Monitoring Centre for Drugs and Drug Addiction. New drugs in Europe, 2012 EMCDDA–Europol 2012 annual report on the implementation of Council Decision 2005/387/JHA. Luxembourg: Publications Office; 2013.
  • Coenen NCB, Dijkstra BAG, Batalla A, et al. Detoxification of a patient with comorbid dependence on phenibut and benzodiazepines by tapering with baclofen: case report. J Clin Psychopharmacol. 2019;39(5):511–514.
  • Högberg L, Szabó I, Ruusa J. Psychotic symptoms during phenibut (beta-phenyl-gamma-aminobutyric acid) withdrawal. J Subst Use. 2013;18(4):335–338.
  • Koppen A, van Riel A, Roelen C, et al. Reports of phenibut usage to the Dutch Poisons Information Center (DPIC). Clin Toxicol. 2015;53:716–717.
  • Downes MA, Berling IL, Mostafa A, et al. Acute behavioural disturbance associated with phenibut purchased via an internet supplier. Clin Toxicol (Phila)). 2015;53(7):636–638.
  • Wong A, Little M, Caldicott D, et al. Analytically confirmed recreational use of phenibut (β-phenyl-γ-aminobutyric acid) bought over the internet. Clin Toxicol (Phila)). 2015;53(7):783–784.
  • Clinical Guidelines on Drug Misuse and Dependence Update 2017 Independent Expert Working Group. Drug misuse and dependence: UK guidelines on clinical management. London: Department of Health; 2017.
  • Sankary S, Canino P, Jackson J. Phenibut overdose. Am J Emerg Med. 2017;35(3):516.e1–516.e2.
  • Cohen PA, Sharfstein J, Kamugisha A, et al. Analysis of ingredients of supplements in the National Institutes of Health supplement database marketed as containing a novel alternative to anabolic steroids. JAMA Netw Open. 2020;3(4):e202818.
  • Get Ahead. Phenibut: your ultimate guide to unlocking your social side & more with this powerful pill; 2014.
  • Kahl KW, Seither JZ, Reidy LJ. LC-MS-MS vs ELISA: validation of a comprehensive urine toxicology screen by LC-MS-MS and a comparison of 100 forensic specimens. J Anal Toxicol. 2019;43(9):734–745.
  • Breindahl T, Hindersson P, Leutscher PDC, et al. New psychoactive substances require a paradigm shift in drug testing in Denmark. Ugeskr Laeger. 2018;180:V07170564.

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