Mechanical insufflation-exsufflation and available funding for Canadian adult patients. A Canadian Thoracic Society Position Statement

References

• Polverino M, Polverino F, Fasolino M, et al. Anatomy and neuro-pathophysiology of the cough reflex arc. Multidiscip Respir Med. 2012;7(1):5 doi:10.1186/2049-6958-7-5.
   PubMedGoogle Scholar
• Bach JR. Mechanical insufflation-exsufflation. Comparison of peak expiratory flows with manually assisted and unassisted coughing techniques. Chest. 1993;104(5):1553–1562. doi:10.1378/chest.104.5.1553.
   PubMed Web of Science ®Google Scholar
• Homnick DN. Mechanical Insufflation-Exsufflation for Airway Mucus Clearance. Respir Care. 2007;52(10):1296–1305.
   PubMed Web of Science ®Google Scholar
• Chatwin M, Toussaint M, Goncalves MR, et al. Airway clearance techniques in neuromuscular disorders: A state of the art review. Respir Med. 2018;136:98–110. doi:10.1016/j.rmed.2018.01.012.
   PubMed Web of Science ®Google Scholar
• Guerin C, Bourdin G, Leray V, et al. Performance of the coughassist insufflation-exsufflation device in the presence of an endotracheal tube or tracheostomy tube: a bench study. Respir Care. 2011;56(8):1108–1114. doi:10.4187/respcare.01121.
   Web of Science ®Google Scholar
• Prevost S, Brooks D, Bwititi P. Mechanical insufflation-exsufflation: Practice patterns among respiratory therapists in ontario. Can J Respir Ther. 2015;51(2):33–38.
   PubMedGoogle Scholar
• Sancho J, Servera E, Vergara P, et al. Mechanical insufflation-exsufflation vs. tracheal suctioning via tracheostomy tubes for patients with amyotrophic lateral sclerosis: a pilot study. Am J Phys Med Rehabil. 2003;82(10):750–753. doi:10.1097/01.PHM.0000087456.28979.2E.
   PubMed Web of Science ®Google Scholar
• Vianello A, Corrado A, Arcaro G, et al. Mechanical insufflation-exsufflation improves outcomes for neuromuscular disease patients with respiratory tract infections. American Journal of Physical Medicine and Rehabilitation. 2005;84(2):83–88. doi:10.1097/01.PHM.0000151941.97266.96.
   PubMed Web of Science ®Google Scholar
• Chatwin M, Ross E, Hart N, et al. Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness. Eur Respir J. 2003;21(3):502–508. doi:10.1183/09031936.03.00048102.
   Web of Science ®Google Scholar
• Morrow B, Zampoli M, van Aswegen H, et al. Mechanical insufflation-exsufflation for people with neuromuscular disorders. Cochrane Database Syst Rev. 2013;(12):CD010044. doi:10.1002/14651858.CD010044.pub2.
   Web of Science ®Google Scholar
• Auger C, Hernando V, Galmiche H. Use of Mechanical Insufflation-Exsufflation Devices for Airway Clearance in Subjects With Neuromuscular Disease. Respir Care. 2017;62(2):236–245. doi:10.4187/respcare.04877.
   PubMed Web of Science ®Google Scholar
• McKim D, Road J, Avendano M, Canadian Thoracic Society Home Mechanical Ventilation Committee, et al. Home mechanical ventilation: A Canadian Thoracic Society clinical practice guideline. Can Respir J. 2011;18(4):197–215. doi:10.1155/2011/139769.
   PubMed Web of Science ®Google Scholar
• Strickland SL, Rubin BK, Drescher GS, et al. AARC clinical practice guideline: effectiveness of nonpharmacologic airway clearance therapies in hospitalized patients. Respir Care. 2013;58(12):2187–2193. doi:10.4187/respcare.02925.
   Web of Science ®Google Scholar
• Gomez-Merino E, Sancho J, Marin J, et al. Mechanical insufflation-exsufflation: pressure, volume, and flow relationships and the adequacy of the manufacturer's guidelines. Am J Phys Med Rehabil. 2002;81(8):579–583. doi:10.1097/00002060-200208000-00004.
   PubMed Web of Science ®Google Scholar
• Rose L, Adhikari NK, Poon J, et al. Cough Augmentation Techniques in the Critically Ill: A Canadian National Survey. Respir Care. 2016;61(10):1360–1368. doi:10.4187/respcare.04775.
   Web of Science ®Google Scholar
• Mahede T, Davis G, Rutkay A, et al. Use of mechanical airway clearance devices in the home by people with neuromuscular disorders: effects on health service use and lifestyle benefits. Orphanet J Rare Dis. 2015;10:54 doi:10.1186/s13023-015-0267-0.
   Web of Science ®Google Scholar
• Vitacca M, Paneroni M, Trainini D, et al. At home and on demand mechanical cough assistance program for patients with amyotrophic lateral sclerosis. Am J Phys Med Rehabil. 2010;89(5):401–406. doi:10.1097/PHM.0b013e3181d89760.
   Web of Science ®Google Scholar
• Bach JR, Ishikawa Y, Kim H. Prevention of pulmonary morbidity for patients with Duchenne muscular dystrophy. Chest. 1997;112(4):1024–1028. doi:10.1378/chest.112.4.1024.
   PubMed Web of Science ®Google Scholar
• Greenhalgh T, Thorne S, Malterud K. Time to challenge the spurious hierarchy of systematic over narrative reviews? Eur J Clin Invest. 2018;48(6):e12931 doi:10.1111/eci.12931.
   PubMed Web of Science ®Google Scholar
• Jahan N, Naveed S, Zeshan M, et al. How to Conduct a Systematic Review: A Narrative Literature Review. Cureus. 2016;8(11):e864 doi:10.7759/cureus.864.
   PubMed Web of Science ®Google Scholar
• Ferrari R. Writing narrative style literature reviews. Medical Writing. 2015;24(4):230–235. doi:10.1179/2047480615Z.000000000329.
   Google Scholar
• Volpe MS, Naves JM, Ribeiro GG, et al. Airway Clearance With an Optimized Mechanical Insufflation-Exsufflation Maneuver. Respir Care. 2018;63(10):1214–1222. doi:10.4187/respcare.05965.
   Web of Science ®Google Scholar
• Andersen T, Sandnes A, Brekka AK, et al. Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis. Thorax. 2017;72(3):221–229. doi:10.1136/thoraxjnl-2015-207555.
   PubMed Web of Science ®Google Scholar
• Bach J, Upadhyaya N. Association of Need for Tracheotomy With Decreasing Mechanical In-Exsufflation Flows in Amyotrophic Lateral Sclerosis. Am J Phys Med Rehabil. 2018;97(4):e20–e22. doi:10.1097/PHM.0000000000000755.
   Web of Science ®Google Scholar
• Andersen PM, Abrahams S, Borasio GD, EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis, et al. EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)-revised report of an EFNS task force . Eur J Neurol. 2012;19(3):360–375. doi:10.1111/j.1468-1331.2011.03501.x.
   PubMed Web of Science ®Google Scholar
• Sancho J, Servera E, Diaz J, et al. Efficacy of mechanical insufflation-exsufflation in medically stable patients with amyotrophic lateral sclerosis. Chest. 2004;125(4):1400–1403. doi:10.1378/chest.125.4.1400.
   PubMed Web of Science ®Google Scholar
• Rafiq MK, Bradburn M, Proctor AR, et al. A preliminary randomized trial of the mechanical insufflator-exsufflator versus breath-stacking technique in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(7-8):448–455. doi:10.3109/21678421.2015.1051992.
   PubMed Web of Science ®Google Scholar
• Senent C, Golmard JL, Salachas F, et al. A comparison of assisted cough techniques in stable patients with severe respiratory insufficiency due to amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2011;12(1):26–32. doi:10.3109/17482968.2010.535541.
   PubMed Web of Science ®Google Scholar
• Sancho J, Bures E, de La Asuncion S, et al. Effect of High-Frequency Oscillations on Cough Peak Flows Generated by Mechanical In-Exsufflation in Medically Stable Subjects With Amyotrophic Lateral Sclerosis. Respir Care. 2016;61(8):1051–1058. doi:10.4187/respcare.04552.
   Web of Science ®Google Scholar
• Camela F, Gallucci M, Ricci G. Cough and airway clearance in Duchenne muscular dystrophy. Paediatr Respir Rev. 2019;31:35–39. doi:10.1016/j.prrv.2018.11.001.
   Web of Science ®Google Scholar
• Cesareo A, LoMauro A, Santi M, et al. Acute Effects of Mechanical Insufflation-Exsufflation on the Breathing Pattern in Stable Subjects With Duchenne Muscular Dystrophy. Respir Care. 2018;63(8):955–965. doi:10.4187/respcare.05895.
   Web of Science ®Google Scholar
• Ishikawa Y, Miura T, Ishikawa Y, et al. Duchenne muscular dystrophy: survival by cardio-respiratory interventions. Neuromuscular Disorders. 2011;21(1):47–51. doi:10.1016/j.nmd.2010.09.006.
   PubMed Web of Science ®Google Scholar
• Ishikawa Y, Bach JR, Minami R. Cardioprotection for Duchenne’s muscular dystrophy. Am Heart J. 1999;137(5):895–902. doi:10.1016/S0002-8703(99)70414-X.
   Web of Science ®Google Scholar
• Miura T, Takami A, Makino M, et al. Rate of oral intake and effects of mechanical insufflation-exsufflation on pulmonary complications in patients with duchenne muscular dystrophy. J Phys Ther Sci. 2017;29(3):487–490. doi:10.1589/jpts.29.487.
   Google Scholar
• Lee Y, Kim J, Jin Y. The efficacy of pulmonary rehabilitation using a mechanical in-exsufflator and feedback respiratory training for cervical cord injured patients. J Phys Ther Sci. 2012;24(1):89–92. doi:10.1589/jpts.24.89.
   Google Scholar
• Crew J, Svircev J, Burns S. Mechanical insufflation-exsufflation device prescription for outpatients with tetraplegia. J Spinal Cord Med. 2010;33(2):128–134. doi:10.1080/10790268.2010.11689687.
   PubMed Web of Science ®Google Scholar
• Pillastrini P, Bordini S, Bazzocchi G, et al. Study of the effectiveness of bronchial clearance in subjects with upper spinal cord injuries: examination of a rehabilitation programme involving mechanical insufflation and exsufflation. Spinal Cord. 2006;44(10):614–616. doi:10.1038/sj.sc.3101870.
   PubMed Web of Science ®Google Scholar
• Schmitt J, Stiens S, Trincher R, et al. Survey of use of the insufflator-exsufflator in patients with spinal cord injury. J Spinal Cord Med. 2007;30(2):127–130. doi:10.1080/10790268.2007.11753923.
   PubMed Web of Science ®Google Scholar
• Stehling F, Bouikidis A, Schara U, et al. Mechanical insufflation/exsufflation improves vital capacity in neuromuscular disorders. Chron Respir Dis. 2015;12(1):31–35. doi:10.1177/1479972314562209.
   Web of Science ®Google Scholar
• Bento J, Gonçalves M, Silva N, et al. Indications and Compliance of Home Mechanical Insufflation-Exsufflation in Patients with Neuromuscular Diseases. Archivos de Bronconeumología (English Edition). 2010;46(8):420–425. doi:10.1016/S1579-2129(10)70100-2.
   Web of Science ®Google Scholar
• Kim SM, Choi WA, Won YH, et al. A Comparison of Cough Assistance Techniques in Patients with Respiratory Muscle Weakness. Yonsei Med J. 2016;57(6):1488–1493. doi:10.3349/ymj.2016.57.6.1488.
   PubMed Web of Science ®Google Scholar
• Lacombe M, Del Amo Castrillo L, Bore A, et al. Comparison of three cough-augmentation techniques in neuromuscular patients: mechanical insufflation combined with manually assisted cough, insufflation-exsufflation alone and insufflation-exsufflation combined with manually assisted cough. Respiration. 2014;88(3):215–222. doi:10.1159/000364911.
   PubMed Web of Science ®Google Scholar
• Chatwin M, Simonds AK. The addition of mechanical insufflation/exsufflation shortens airway-clearance sessions in neuromuscular patients with chest infection. Respir Care. 2009;54(11):1473–1479.
   Web of Science ®Google Scholar
• Saghebi S, Sharafeh S, Kharabian S, et al. The effectiveness of mechanical insufflator/exsufflator in sputum discharge among intensive care unit admitted patients. Arch Crit Care Med. 2017;In Press (In Press):e60468. doi:10.5812/accm.60468.
   Google Scholar
• Phillips MF, Quinlivan RC, Edwards RH, et al. Changes in spirometry over time as a prognostic marker in patients with Duchenne Muscular Dystrophy. Am J Respir Crit Care Med. 2001;164(12):2191–2194. doi:10.1164/rccm2103052.
   Web of Science ®Google Scholar
• Smina M, Salam A, Khamiees M, et al. Cough peak flows and extubation outcomes. Chest. 2003;124(1):262–268. doi:10.1378/chest.124.1.262.
   Web of Science ®Google Scholar
• Nakagawa N, Franchini M, Driusso P, et al. Mucociliary clearance is impaired in acutely ill patients. Chest. 2005;128(4):2772–2777. doi:10.1378/chest.128.4.2772.
   PubMed Web of Science ®Google Scholar
• Jongerden I, Rovers M, Grypdonck M, et al. Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysis. Crit Care Med. 2007;35(1):260–270. doi:10.1097/01.CCM.0000251126.45980.E8.
   Web of Science ®Google Scholar
• Puntillo K, Max A, Timsit J, et al. Determinants of procedural pain intensity in the intensive care unit. The Europain® study. Am J Respir Crit Care Med. 2013;189(1):131126070246006– 131126070246047. doi:10.1164/rccm.201306-1174OC.
   Web of Science ®Google Scholar
• Sánchez-García M, Santos P, Rodriguez-Trigo G, et al. Preliminary experience on the safety and tolerability of mechanical "insufflation-exsufflation" in subjects with artificial airway. Intensive Care Med Exp. 2018;6(1):8 doi:10.1186/s40635-018-0173-6.
   Google Scholar
• Ferreira de Camillis ML, Savi A, Goulart Rosa R, et al. Effects of Mechanical Insufflation-Exsufflation on Airway Mucus Clearance Among Mechanically Ventilated ICU Subjects. Respir Care. 2018;63(12):1471–1477. doi:10.4187/respcare.06253.
   Web of Science ®Google Scholar
• Nunes L, Rizzetti R, Neves D, et al. Mechanical insufflation/exsufflation improves respiratory mechanics in critical care: Randomized crossover trial. Respir Physiol Neurobiol. 2019;266:115–120. doi:10.1016/j.resp.2019.05.008.
   Web of Science ®Google Scholar
• Bach JR. Continuous noninvasive ventilation for patients with neuromuscular disease and spinal cord injury. Semin Respir Crit Care Med. 2002;23(3):283–292. doi:10.1055/s-2002-33037.
   Web of Science ®Google Scholar
• Winck J, Goncalves M, Lourenco C, et al. Effects of mechanical insufflation-exsufflation on respiratory parameters for patients with chronic airway secretion encumbrance. Chest. 2004;126(3):774–780. doi:10.1378/chest.126.3.774.
   PubMed Web of Science ®Google Scholar
• Dale CM, King J, Nonoyama M, CANuVENT group, et al. Transitions to Home Mechanical Ventilation: The Experiences of Canadian Ventilator-Assisted Adults and Their Family Caregivers. Ann Am Thorac Soc. 2018;15(3):357–364. doi:10.1513/AnnalsATS.201708-663OC.
   Web of Science ®Google Scholar
• Siewers V, Holmøy T, Frich JC. Experiences with using mechanical in–exsufflation in amyotrophic lateral sclerosis. European Journal of Physiotherapy. 2013;15(4):201–207. doi:10.3109/21679169.2013.834513.
   Google Scholar
• Nonoyama ML, McKim DA, Road J, et al. Healthcare utilisation and costs of home mechanical ventilation. Thorax. 2018;73(7):644–651. doi:10.1136/thoraxjnl-2017-211138.
   Web of Science ®Google Scholar