Publication Cover
Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 20, 2003 - Issue 5
185
Views
33
CrossRef citations to date
0
Altmetric
Original

Zeitgeber Hierarchy in Humans: Resetting the Circadian Phase Positions of Blind People Using Melatonin

, , , &
Pages 837-852 | Received 27 Feb 2003, Accepted 16 May 2003, Published online: 07 Jul 2009

References

  • Arendt J., Skene D. J., Middleton B., Lockley S. W., Deacon S. Efficacy of melatonin treatment in jet lag, shift work, and blindness. J. Biol. Rhythms 1997; 12: 604–617
  • Baehr E. K., Lyda J. L., Eastman C. I., Revelle W., Zee P. C. Nocturnal exercise phase‐delays the circadian rhythms of older adults (Abstract). Sleep 2001; 24: A86–A87
  • Bobbert A. C., Riethoven J. J. Feedback in the rabbit's central circadian system, revealed by the changes in its free‐running food intake pattern induced by blinding, cervical sypathectomy, pinealectomy, and melatonin administration. J. Biol. Rhythms 1991; 6: 263–278
  • Boivin D. B., Czeisler C. A. Resetting of circadian melatonin and cortisol rhythms in humans by ordinary room light. Neuro Report 1998; 9: 779–782
  • Boivin D. B., Duffey J. F., Kronauer R. E., Czeisler C. A. Dose‐response relationships for resetting of human circadian clock by light. Nature 1996; 379: 540–541
  • Buxton O. M., Frant S. A., L'Hermite‐Baleriaux M., Leproult R., Turek F. W., Van Cauter E. Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms. Am. J. Physiol.‐Endocrinol. Metabol. 1997; 273: E536–542
  • Buxton O. M., Lee C. W., L'Hermite‐Baleriaux M., Turek F. W., Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 2003; 284: R714–R724
  • Campbell S. S., Murphy P. J. Extraocular circadian phototransduction in humans. Sleep 1998; 279: 396–399
  • Czeisler C. A. Commentary: evidence for melatonin as a circadian phase‐shifting agent. J. Biol. Rhythms 1997; 12: 618–623
  • Czeisler C. A., Shanahan T. L., Klerman E. B., Martens H., Brotman D. J., Emens J. S., Klein T., Rizzo J. F. Suppression of melatonin secretion in some blind patients by exposure to bright light. New Engl. J. Med. 1995; 332: 6–11
  • Deacon S., Arendt J. Posture influences melatonin concentrations in plasma and saliva in humans. Neurosci. Lett. 1994; 167: 191–194
  • Dijk D., Duffy J. F., Riel E., Shanahan T. L., Czeisler C. A. Ageing and the circadian and homeostatic regulation of human sleep during forced desynchrony of rest, melatonin and temperature rhythms. J. Physiol. 1999; 516: 611–627
  • Earl C., O'Occhio M., Kennaway D., Seamark R. Serum melatonin profiles and endocrine responses of ewes exposed to a pulse of light late in the dark phase. Endocrinology 1985; 117: 226–230
  • Eastman C. I., Hoese E. K., Youngstedt S. D., Liu L. Phase‐shifting human circadian rhythms with exercise during the night shift. Physiol. Behav. 1995; 58: 1287–1291
  • Eastman C. I., Martin S. K., Hebert M. Failure of extraocular light to facilitate circadian rhythm reentrainment in humans. Chronobiol. Int. 2000; 17: 807–826
  • Folkard S., Arendt J., Aldhous M., Kennett H. Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms. Neurosci. Lett. 1990; 113: 193–198
  • Kendall A. R., Lewy A. J., Sack R. L. Effects of aging on the intrinsic circadian period of totally blind humans. J. Biol. Rhythms 2001; 16: 87–95
  • Klerman E. B., Rimmer D. W., Dijk D., Kronauer R. E., Rizzo J. F., III, Czeisler C. A. Nonphotic entrainment of the human circadian pacemaker. Am. J. Physiol.‐Reg. 1998; 43: R991–996
  • Klerman E. B., Shanahan T. L., Brotman D. J., Rimmer D. W., Emens J. S., Rizzo J. F., Czeisler C. A. Photic resetting of the human circadian pacemaker in the absence of conscious vision. J. Biol. Rhythms 2002; 17: 548–555
  • Krieger D. T., Rizzo F. Circadian periodicity of plasma 11‐hydroxycorticosteroid levels in subjects with partial and absent light perception. Neuroendocrinology 1971; 8: 165–179
  • Lewy A. J. Human plasma melatonin studies: effects of light and implications for biological rhythm research. Melatonin: Current Status and Perspectives. Advances in the Biosciences, N. Birau, W. Scholoot. Pergamon Press, Oxford 1981; 29: 397–400
  • Lewy A. J., Markey S. P. Analysis of melatonin in human plasma by gas chromatography negative chemical ionization mass spectrometry. Science 1978; 201: 741–743
  • Lewy A. J., Newsome D. A. Different types of melatonin circadian secretory rhythms in some blind subjects. J. Clin. Endocrinol. Metabol. 1983; 56: 1103–1107
  • Lewy A. J., Ahmed S., Jackson J. M. L., Sack R. L. Melatonin shifts circadian rhythms according to a phase‐response curve. Chronobiol. Int. 1992; 9: 380–392
  • Lewy A. J., Sack R. L., Boney R. S., Clemons A. A., Anderson N. R., Pen S. D., Bauer V. K., Cutler N. L., Harker C. T. Assays for measuring the dim light melatonin onset (DLMO) in human plasma. Sleep Res. 1997; 26: 733
  • Lewy A. J., Bauer V. K., Ahmed S., et al. The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light. Chronobiol. Int. 1998a; 15: 71–83
  • Lewy A. J., Bauer V. K., Cutler N. L., Sack R. L., Ahmed S., Thomas K. H., Blood M. L., Latham Jackson J. M. Morning versus evening light treatment of patients with winter depression. Arch. Gen. Psychiat. 1998b; 55: 890–896
  • Lewy A. J., Bauer V. K., Hasler B. P., Kendall A. R., Pires L. N., Sack R. L. Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin. Brain Res. 2001a; 918: 96–100
  • Lewy A. J., Hasler B. P., Emens J. S., Sack R. L. Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin. Neurosci. Lett. 2001b; 313: 158–160
  • Lewy A. J., Emens J. S., Sack R. L., Hasler B. P., Bernert R. A. Low, but not high, doses of melatonin entrained a free‐running blind person with a long circadian period. Chronobiol. Int. 2002; 19: 649–658
  • Lockley S. W., Skene D. J., James K., Thapan K., Wright J., Arendt H. Melatonin administration can entrain the free‐running circadian system of blind subjects. J. Endocrinol. 2000; 164: R1–R6
  • Lupi D., Cooper H. M., Froehlich A., Standford L., McCall M. A., Foster R. G. Transgenic ablation of rod photoreceptors alters the circadian phenotype of mice. Neuroscience 1998; 89: 363–374
  • Lynch H. J., Ozaki Y., Shakal D., Wurtman R. J. Melatonin excretion of man and rats: effect of time of day, sleep, pinealectomy and food consumption. Int. J. Biometeorol. 1975; 19: 267–279
  • Martin S., Eastman C. I. Sleep logs of young adults with self‐selected sleep times predict the dim light melatonin onset. Chronobiol. Int. 2002; 19: 695–707
  • Middleton B., Arendt J., Stone B. M. Complex effects of melatonin on human circadian rhythms in constant dim light. J. Biol. Rhythms 1997; 12: 467–477
  • Miles L. E. M., Raynal D. M., Wilson M. A. Blind man living in normal society has circadian rhythms of 24.9 hours. Science 1977; 198: 421–423
  • Miyazaki T., Hashimoto S., Masubuchi S., Honma S., Honma K. Phase‐advance shifts of human circadian pacemaker are accelerated by daytime physical exercise. Am. J. Physiol.‐Reg. 2001; 281: R197–R205
  • Nathan P. J., Jeyaseelan A. S., Burrows G. D., Norman T. R. Modulation of plasma melatonin concentrations by changes in posture. J. Pineal Res. 1998; 24(4)219–223
  • Orth D. N., Island D. P. Light synchronization of the circadian rhythm in plasma cortisol (17‐OHCS) concentration in man. J. Clin. Endocrinol. Metabol. 1969; 29: 479–486
  • Orth D., Besser G., King P., Nicholson W. Free‐running circadian plasma cortisol rhythm in a blind human subject. Clin. Endocrinol. 1979; 10: 603–617
  • Palm L., Blennow G., Wetterberg L. Correction of non‐24‐hour sleep/wake cycle by melatonin in a blind retarded boy. Ann. Neurol. 1991; 29: 336–339
  • Piercy J., Lack L. Daily exercise can shift the endogenous circadian phase (Abstract). Sleep Res. 1988; 17: 393
  • Redman J., Armstrong S., Ng K. T. Free‐running activity rhythms in the rat: entrainment by melatonin. Science 1983; 219: 1089–1091
  • Sack R. L., Stevenson J., Lewy A. J. Entrainment of a previously free‐running blind human with melatonin administration. Sleep Res. 1990; 19: 404
  • Sack R. L., Brandes R. L., E. A. D., Pen S., Nordstrom S., Lewy A. J. Melatonin entrains free-running circadian rhythms in a totally blind person. Sleep 1999a; 22(Supp)S138
  • Sack R. L., Brandes R. L., Lewy A. J. Totally blind people with free-running circadian rhythms can be normally entrained with melatonin. Sleep Research Online 1999b; 2(Supp 1)624
  • Sack R. L., Brandes R. R., Kendall A. R., Lewy A. J. Entrainment of circadian rhythms in a totally blind subject using low dose melatonin. Sleep 2000a; 23: A194
  • Sack R. L., Brandes R. W., Kendall A. R., Lewy A. J. Entrainment of free-running circadian rhythms by melatonin in blind people. New Engl. J. Med. 2000b; 343: 1070–1077
  • Shanahan T. L., Czeisler C. A. Physiological effects of light on the human circadian pacemaker. Semin. Perinatol. 2000; 24: 299–320
  • Skene D. J., Lockley S. W., Arendt J. Melatonin entrains the free‐running circadian rhythms of some blind subjects. Sleep Research Online 1999a; 2: 725
  • Skene D. J., Lockley S. W., Arendt J. Melatonin in circadian sleep disorders in the blind. Biol. Signal. Recept. 1999b; 8: 90–95
  • Underwood H. Circadian organization in the lizard Seeloporus occidentalis: the effects of pinealectomy, blinding, and melatonin. J. Comp. Physiol. 1981; 141: 537–547
  • Underwood H. Circadian rhythms in lizards: phase response curve for melatonin. J. Pineal Res. 1986; 3: 187–196
  • Van Reeth O., Sturis J., Byrne M. M., Blackman J. D., L'Hermite‐Baleriaux M., Leproult R., Oliner C., Refetoff S., Turek F. W., Van Cauter E. Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men. Am. J. Physiol. 1994; 266: E964–E974
  • Wright K. P., Jr., Czeisler C. A. Absence of circadian phase resetting in response to bright light behind the knees. Science 2002; 297: 571
  • Wright K. P., Jr., Hughes R. J., Kronauer R. E., Dijk D., Czeisler C. A. Intrinsic near‐24‐h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans. PNAS 2001; 98: 14027–14032
  • Zaidan R., Geoffriau M., Brun J., Taillard J., Bureau C., Chazot G., Claustrat B. Melatonin is able to influence its secretion in humans: description of a phase‐response curve. Neuroendocrinology 1994; 60: 105–112
  • Zeitzer J. M., Dijk D. J., Kronauer R. E., Brown E. N., Czeisler C. A. Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J. Physiol. 2000; 526: 695–702

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.