Apoptosis in Lymphocytic Leukemias and Lymphomas

REFERENCES

• Harris N.L., Jaffe E.S., Stein H., Banks P.M., Chan J.K., Cleary M.L., Delsol G., De Wolf-Peeters C., Falini B., Gatter K.C. A Revised European–American Classification of Lymphoid Neoplasms: A Proposal from the International Lymphoma Study Group. Blood 1994; 84: 1361–1392
   PubMed Web of Science ®Google Scholar
• Harris N.L., Jaffe E.S., Diebold J., Flandrin G., Muller-Hermelink H.K., Vardiman J., Lister T.A., Bloomfield C.D. World Health Organization Classification of Neoplastic Diseases of the Hematopoietic and Lymphoid Tissues: Report of the Clinical Advisory Committee Meeting-Airlie House, Virginia, November 1997. J. Clin. Oncol. 1999; 17: 3835–3849
   PubMed Web of Science ®Google Scholar
• Graninger W.B., Seto M., Boutain B., Goldman P., Korsmeyer S.J. Expression of Bcl-2 and Bcl-2–Ig Fusion Transcripts in Normal and Neoplastic Cells. J. Clin. Invest. 1987; 80: 1512–1515
   PubMed Web of Science ®Google Scholar
• Korsmeyer S.J. Chromosomal Translocations in Lymphoid Malignancies Reveal Novel Proto-oncogenes. Annu. Rev. Immunol. 1992; 10: 785–807
   PubMed Web of Science ®Google Scholar
• Dalla-Favera R., Gaidano G. Molecular Biology of Lymphomas. Principles and Practice of Oncology, V.T. DeVita, S. Hellman, S.A. Rosenberg. Lippincott Williams and Wilkins, Philadelphia, PA 2001
   Google Scholar
• Gottardi D., Alfarano A., De Leo A.M., Stacchini A., Aragno M., Rigo A., Veneri D., Zanotti R., Pizzolo G., Caligaris-Cappio F. In Leukaemic CD5+ B Cells the Expression of BCL-2 Gene Family Is Shifted Toward Protection from Apoptosis. Br. J. Haematol. 1996; 94: 612–618
   PubMed Web of Science ®Google Scholar
• Kitada S., Andersen J., Akar S., Zapata J.M., Takayama S., Krajewski S., Wang H.G., Zhang X., Bullrich F., Croce C.M., Rai K., Hines J., Reed J.C. Expression of Apoptosis-Regulating Proteins in Chronic Lymphocytic Leukemia: Correlations with In Vitro and In Vivo Chemoresponses. Blood 1998; 91: 3379–3389
   PubMed Web of Science ®Google Scholar
• Bernal A., Pastore R.P., Asgary Z., Keller S.A., Cesarman E., Liou H.-C., Schattner E.J. Survival of Leukemic B Cells Promoted by Engagement of the Antigen Receptor. Blood 2001; 98: 3050–3057
   PubMed Web of Science ®Google Scholar
• Tsukahara T., Kannagi M., Ohashi T., Kato H., Arai M., Nunez G., Iwanaga Y., Yamamoto N., Ohtani K., Nakamura M., Fujii M. Induction of Bcl-x(L) Expression by Human T-Cell Leukemia Virus Type 1 Tax Through NF-kappaB in Apoptosis-Resistant T-Cell Transfectants with Tax. J. Virol. 1999; 73: 7981–7987
   PubMed Web of Science ®Google Scholar
• Kawakami A., Nakashima T., Sakai H., Urayama S., Yamasaki S., Hida A., Tsuboi M., Nakamura H., Ida H., Migita K., Kawabe Y., Eguchi K. Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-kappaB Nuclear Translocation. Blood 1999; 94: 3847–3854
   PubMed Web of Science ®Google Scholar
• Bakhshi A., Jensen J.P., Goldman P., Wright J.J., McBride O.W., Epstein A.L., Korsmeyer S.J. Cloning the Chromosomal Breakpoint of t(14; 18) Human Lymphomas: Clustering Around JH on Chromosome 14 and Near a Transcriptional Unit on 18. Cell 1985; 41: 899–906
   PubMed Web of Science ®Google Scholar
• Tsujimoto Y., Cossman J., Jaffe E., Croce C.M. Involvement of the Bcl-2 Gene in Human Follicular Lymphoma. Science 1985; 228: 1440–1443
   PubMed Web of Science ®Google Scholar
• Weiss L.M., Warnke R.A., Sklar J., Cleary M.L. Molecular Analysis of the t(14; 18) Chromosomal Translocation in Malignant Lymphomas. N. Engl. J. Med. 1987; 317: 1185–1189
   PubMed Web of Science ®Google Scholar
• Krajewski S., Bodrug S., Gascoyne R., Berean K., Krajewska M., Reed J.C. Immunohistochemical Analysis of Mcl-1 and Bcl-2 Proteins in Normal and Neoplastic Lymph Nodes. Am. J. Pathol. 1994; 145: 515–525
   PubMed Web of Science ®Google Scholar
• Martinez-Valdez H., Guret C., de Bouteiller O., Fugier I., Banchereau J., Liu Y.J. Human Germinal Center B Cells Express the Apoptosis-Inducing Genes Fas, c-myc, p53, and bax But Not the Survival Gene bcl-2. J. Exp. Med. 1996; 183: 971–977
   PubMed Web of Science ®Google Scholar
• Rathmell J.C., Thompson C.B. The Central Effectors of Cell Death in the Immune System. Annu. Rev. Immunol. 1999; 17: 781–828
   PubMed Web of Science ®Google Scholar
• Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., Wang X. Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked. Science 1997; 275: 1129–1132
   PubMed Web of Science ®Google Scholar
• Shimizu S., Narita M., Tsujimoto Y. Bcl-2 Family Proteins Regulate the Release of Apoptogenic Cytochrome c by the Mitochondrial Channel VDAC. Nature 1999; 399: 483–487
   PubMed Web of Science ®Google Scholar
• Bouchon A., Krammer P.H., Walczak H. Critical Role for Mitochondria in B Cell Receptor-Mediated Apoptosis. Eur. J. Immunol. 2000; 30: 69–77
   PubMed Web of Science ®Google Scholar
• Muchmore S.W., Sattler M., Liang H., Meadows R.P., Harlan J.E., Yoon H.S., Nettesheim D., Chang B.S., Thompson C.B., Wong S.L., Ng S.L., Fesik S.W. X-Ray and NMR Structure of Human Bcl-xL, an Inhibitor of Programmed Cell Death. Nature 1996; 381: 335–341
   PubMed Web of Science ®Google Scholar
• Reed J.C., Jurgensmeier J.M., Matsuyama S. Bcl-2 Family Proteins and Mitochondria. Biochim. Biophys. Acta 1998; 1366: 127–137
   PubMed Web of Science ®Google Scholar
• Shi Y. A Structural View of Mitochondria-Mediated Apoptosis. Nat. Struct. Biol. 2001; 8: 394–401
   PubMedGoogle Scholar
• Wang H.G., Pathan N., Ethell I.M., Krajewski S., Yamaguchi Y., Shibasaki F., McKeon F., Bobo T., Franke T.F., Reed J.C. Ca2+-Induced Apoptosis Through Calcineurin Dephosphorylation of BAD. Science 1999; 284: 339–343
   PubMed Web of Science ®Google Scholar
• Zha J., Weiler S., Oh K.J., Wei M.C., Korsmeyer S.J. Posttranslational N-Myristoylation of BID as a Molecular Switch for Targeting Mitochondria and Apoptosis. Science 2000; 290: 1761–1765
   PubMed Web of Science ®Google Scholar
• Luo X., Budihardjo I., Zou H., Slaughter C., Wang X. Bid, a Bcl2 Interacting Protein, Mediates Cytochrome C Release from Mitochondria in Response to Activation of Cell Surface Death Receptors. Cell 1998; 94: 481–490
   PubMed Web of Science ®Google Scholar
• Rozman C., Montserrat E. Chronic Lymphocytic Leukemia. N. Engl. J. Med. 1995; 333: 1052–1057
   PubMed Web of Science ®Google Scholar
• Caligaris-Cappio F., Hamblin T.J. B-Cell Chronic Lymphocytic Leukemia: A Bird of a Different Feather. J. Clin. Oncol. 1999; 17: 399–408
   PubMed Web of Science ®Google Scholar
• Schroeder H.W., Jr., Dighiero G. The Pathogenesis of Chronic Lymphocytic Leukemia: Analysis of the Antibody Repertoire. Immunol. Today 1994; 15: 288–294
   PubMedGoogle Scholar
• Caligaris-Cappio F. B-Chronic Lymphocytic Leukemia: A Malignancy of Anti-self B Cells. Blood 1996; 87: 2615–2620
   PubMed Web of Science ®Google Scholar
• Dameshek W. Chronic Lymphocytic Leukemia—An Accumulative Disease of Immunolgically Incompetent Lymphocytes. Blood 1967; 29: 566–584
   PubMed Web of Science ®Google Scholar
• Schattner E.J. CD40 Ligand in CLL Pathogenesis and Therapy. Leuk. Lymphoma 2000; 37: 461–472
   PubMed Web of Science ®Google Scholar
• Lagneaux L., Delforge A., Bron D., De Bruyn C., Stryckmans P. Chronic Lymphocytic Leukemic B Cells But Not Normal B Cells are Rescued from Apoptosis by Contact with Normal Bone Marrow Stromal Cells. Blood 1998; 91: 2387–2396
   PubMed Web of Science ®Google Scholar
• Gamberale R., Geffner J.R., Trevani A., Chernavsky A., Scolnik M., Arrosagaray G., Sarmiento M., Giordano M. Immune Complexes Inhibit Apoptosis of Chronic Lymphocytic Leukaemia B Cells. Br. J. Haematol. 1999; 107: 870–876
   PubMed Web of Science ®Google Scholar
• Cordingley F.T., Bianchi A., Hoffbrand A.V., Reittie J.E., Heslop H.E., Vyakarnam A., Turner M., Meager A., Brenner M.K. Tumour Necrosis Factor as an Autocrine Tumour Growth Factor for Chronic B-Cell Malignancies. Lancet 1988; 1: 969–971
   PubMed Web of Science ®Google Scholar
• Dancescu M., Rubio-Trujillo M., Biron G., Bron D., Delespesse G., Sarfati M. Interleukin 4 Protects Chronic Lymphocytic Leukemic B Cells from Death by Apoptosis and Upregulates Bcl-2 Expression. J. Exp. Med. 1992; 176: 1319–1326
   PubMed Web of Science ®Google Scholar
• Romano M.F., Lamberti A., Tassone P., Alfinito F., Costantini S., Chiurazzi F., Defrance T., Bonelli P., Tuccillo F., Turco M.C., Venuta S. Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells. Blood 1998; 92: 990–995
   PubMed Web of Science ®Google Scholar
• Furman R.R., Asgary Z., Mascarenhas J.O., Liou H.-C., Schattner E.J. Modulation of NF-κB Activity and Apoptosis in Chronic Lymphocytic Leukemia B Cells. J. Immunol. 2000; 164: 2200–2206
   PubMed Web of Science ®Google Scholar
• Kitada S., Zapata J.M., Andreeff M., Reed J.C. Bryostatin and CD40-Ligand Enhance Apoptosis Resistance and Induce Expression of Cell Survival Genes in B-Cell Chronic Lymphocytic Leukaemia. Br. J. Haematol. 1999; 106: 995–1004
   PubMed Web of Science ®Google Scholar
• Wang D., Freeman G.J., Levine H., Ritz J., Robertson M.J. Role of the CD40 and CD95 (APO-1/Fas) Antigens in the Apoptosis of Human B-Cell Malignancies. Br. J. Haematol. 1997; 97: 409–417
   PubMed Web of Science ®Google Scholar
• Younes A., Snell V., Consoli U., Clodi K., Zhao S., Palmer J.L., Thomas E.K., Armitage R.J., Andreeff M. Elevated Levels of Biologically Active Soluble CD40 Ligand in the Serum of Patients with Chronic Lymphocytic Leukaemia. Br. J. Haematol. 1998; 100: 135–141
   PubMed Web of Science ®Google Scholar
• Granziero L., Ghia P., Circosta P., Gottardi D., Strola G., Geuna M., Montagna L., Piccoli P., Chilosi M., Caligaris-Cappio F. Survivin is Expressed on CD40 Stimulation and Interfaces Proliferation and Apoptosis in B-Cell Chronic Lymphocytic Leukemia. Blood 2001; 97: 2777–2783
   PubMed Web of Science ®Google Scholar
• Roy M., Waldschmidt T., Aruffo A., Ledbetter J.A., Noelle R.J. The Regulation of the Expression of Gp39, the CD40 Ligand, on Normal and Cloned CD4+ T Cells. J. Immunol. 1993; 151: 2497–2510
   PubMed Web of Science ®Google Scholar
• Tallman M.S., Hakimian D. Purine Nucleoside Analogs: Emerging Roles in Indolent Lymphoproliferative Disorders. Blood 1995; 86: 2463–2474
   PubMed Web of Science ®Google Scholar
• Rai K.R., Peterson B.L., Appelbaum F.R., Kolitz J., Elias L., Shepherd L., Hines J., Threatte G.A., Larson R.A., Cheson B.D., Schiffer C.A. Fludarabine Compared with Chlorambucil as Primary Therapy for Chronic Lymphocytic Leukemia. N. Engl. J. Med. 2000; 343: 1750–1757
   PubMed Web of Science ®Google Scholar
• Trentin L., Zambello R., Sancetta R., Facco M., Cerutti A., Perin A., Siviero M., Basso U., Bortolin M., Adami F., Agostini C., Semenzato G. B Lymphocytes from Patients with Chronic Lymphoproliferative Disorders Are Equipped with Different Costimulatory Molecules. Cancer Res. 1997; 57: 4940–4947
   PubMed Web of Science ®Google Scholar
• Schattner E.J., Mascarenhas J., Reyfman I., Koshy M., Woo C., Friedman S.M., Crow M.K. Chronic Lymphocytic Leukemia B Cells Can Express CD40 Ligand and Demonstrate T-Cell Type Costimulatory Capacity. Blood 1998; 91: 2689–2697
   PubMed Web of Science ®Google Scholar
• Clodi K., Asgary Z., Zhao S., Kliche K.-O., Cabanillas F., Andreeff M., Younes A. Coexpression of CD40 and CD40 Ligand in B-Cell Lymphoma Cells. Br. J. Haematol. 1998; 103: 270–275
   PubMed Web of Science ®Google Scholar
• Chen Z., Hagler J., Palombella V.J., Melandri F., Scherer D., Ballard D., Maniatis T. Signal-Induced Site-Specific Phosphorylation Targets I Kappa B Alpha to the Ubiquitin–Proteasome Pathway. Genes Dev. 1995; 9: 1586–1597
   PubMed Web of Science ®Google Scholar
• Barnes P.J., Karin M. Nuclear Factor-kappaB: A Pivotal Transcription Factor in Chronic Inflammatory Diseases. N. Engl. J. Med. 1997; 336: 1066–1071
   PubMed Web of Science ®Google Scholar
• Baeuerle P.A., Baltimore D. NF-kappa B: Ten Years After. Cell 1996; 87: 13–20
   PubMed Web of Science ®Google Scholar
• Ghosh S., May M.J., Kopp E.B. NF-kappaB and Rel Proteins: Evolutionarily Conserved Mediators of Immune Responses. Annu. Rev. Immunol. 1998; 16: 225–260
   PubMed Web of Science ®Google Scholar
• Baldwin A.S. Control of Oncogenesis and Cancer Therapy Resistance by the Transcription Factor NF-kappaB. J. Clin. Invest. 2001; 107: 241–246
   PubMed Web of Science ®Google Scholar
• Beg A.A., Baltimore D. An Essential Role for NF-kappaB in Preventing TNF-Alpha-Induced Cell Death. Science 1996; 274: 782–784
   PubMed Web of Science ®Google Scholar
• Van Antwerp D.J., Martin S.J., Kafri T., Green D.R., Verma I.M. Suppression of TNF-Alpha-Induced Apoptosis by NF-kappaB. Science 1996; 274: 787–789
   PubMed Web of Science ®Google Scholar
• Wang C.Y., Mayo M.W., Baldwin A.S., Jr. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-kappaB. Science 1996; 274: 784–787
   PubMed Web of Science ®Google Scholar
• Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S., Jr. NF-kappaB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation. Science 1998; 281: 1680–1683
   PubMed Web of Science ®Google Scholar
• Wang C.Y., Guttridge D.C., Mayo M.W., Baldwin A.S., Jr. NF-kappaB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 to Preferentially Suppress Chemotherapy-Induced Apoptosis. Mol. Cell. Biol. 1999; 19: 5923–5929
   PubMed Web of Science ®Google Scholar
• Lee H.H., Dadgostar H., Cheng Q., Shu J., Cheng G. NF-kappaB-Mediated Up-Regulation of Bcl-x and Bfl-1/A1 Is Required for CD40 Survival Signaling in B Lymphocytes. Proc. Natl Acad. Sci. USA 1999; 96: 9136–9141
   PubMed Web of Science ®Google Scholar
• Grumont R.J., Rourke I.J., Gerondakis S. Rel-Dependent Induction of A1 Transcription Is Required to Protect B Cells from Antigen Receptor Ligation-Induced Apoptosis. Genes Dev. 1999; 13: 400–411
   PubMed Web of Science ®Google Scholar
• Broder S., Bunn P.A., Jaffe E.S., Blattner W., Gallo R.C., Wong-Staal F., Waldmann T.A., De Vita V.T. NIH Conference, T-Cell Lymphoproliferative Syndrome Associated with Human T-Cell Leukemia/Lymphoma Virus. Ann. Int. Med. 1984; 100: 543–557
   PubMed Web of Science ®Google Scholar
• Kondo T., Nonaka H., Miyamoto N., Yoshida R., Matsue Y., Ohguchi Y., Inouye H., Komoda H., Hinuma Y., Hanaoka M. Incidence of Adult T-Cell Leukemia–Lymphoma and Its Familial Clustering. Int. J. Cancer 1985; 35: 749–751
   PubMed Web of Science ®Google Scholar
• Rosenblatt J.D., Chen I.S., Wachsman W. Infection with HTLV-I and HTLV-II: Evolving Concepts. Semin. Hematol. 1988; 25: 230–246
   PubMed Web of Science ®Google Scholar
• Sarma P.S., Gruber J. Human T-Cell Lymphotropic Viruses in Human Diseases. J. Natl Cancer Inst. 1990; 82: 1100–1106
   PubMed Web of Science ®Google Scholar
• Kuefler P.R., Bunn P.A. Adult T-Cell Leukaemia/Lymphoma. Clin. Haematol. 1986; 15: 695–726
   PubMedGoogle Scholar
• Hollsberg P., Hafler D.A. Seminars in Medicine of the Beth Israel Hospital. Boston. Pathogenesis of Diseases Induced by Human Lymphotropic Virus Type I Infection. N. Engl. J. Med. 1993; 328: 1173–1182
   PubMed Web of Science ®Google Scholar
• Zhao L.J., Giam C.Z. Interaction of the Human T-Cell Lymphotrophic Virus Type I (HTLV-I) Transcriptional Activator Tax with Cellular Factors that Bind Specifically to the 21-Base-Pair Repeats in the HTLV-I Enhancer. Proc. Natl Acad. Sci. USA 1991; 88: 11445–11449
   PubMed Web of Science ®Google Scholar
• Duyao M.P., Kessler D.J., Spicer D.B., Sonenshein G.E. Transactivation of the Murine c-myc Gene by HTLV-1 Tax Is Mediated by NFκB. AIDS Res. Hum. Retrovir. 1992; 8: 752–754
   PubMed Web of Science ®Google Scholar
• Uittenbogaard M.N., Armstrong A.P., Chiaramello A., Nyborg J.K. Human T-Cell Leukemia Virus Type I Tax Protein Represses Gene Expression Through the Basic Helix-Loop-Helix Family of Transcription Factors. J. Biol. Chem. 1994; 269: 22466–22469
   PubMed Web of Science ®Google Scholar
• Perini G., Wagner S., Green M.R. Recognition of bZIP Proteins by the Human T-Cell Leukaemia Virus Transactivator Tax. Nature 1995; 376: 602–605
   PubMed Web of Science ®Google Scholar
• Kwok R.P., Laurance M.E., Lundblad J.R, Goldman P.S., Shih H., Connor L.M., Marriott S.J., Goodman R.H. Control of cAMP-Regulated Enhancers by the Viral Transactivator Tax Through CREB and the Co-activator CBP. Nature 1996; 380: 642–646
   PubMed Web of Science ®Google Scholar
• Kanno T., Franzoso G., Siebenlist U. Human T-Cell Leukemia Virus Type I Tax-Protein-Mediated Activation of NF-kappa B from p100 (NF-kappa B2)-Inhibited Cytoplasmic Reservoirs. Proc. Natl Acad. Sci. USA 1994; 91: 12634–12638
   PubMed Web of Science ®Google Scholar
• Hirai H., Suzuki T., Fujisawa J., Inoue J., Yoshida M. Tax Protein of Human T-Cell Leukemia Virus Type I Binds to the Ankyrin Motifs of Inhibitory Factor kappa B and Induces Nuclear Translocation of Transcription Factor NF-kappa B Proteins for Transcriptional Activation. Proc. Natl Acad. Sci. USA 1994; 91: 3584–3588
   PubMed Web of Science ®Google Scholar
• Beraud C., Sun S.C., Ganchi P., Ballard D.W., Greene W.C. Human T-Cell Leukemia Virus Type I Tax Associates with and Is Negatively Regulated by the NF-kappa B2 p100 Gene Product: Implications for Viral Latency. Mol. Cell. Biol. 1994; 14: 1374–1382
   PubMed Web of Science ®Google Scholar
• Yin M.J., Christerson L.B., Yamamoto Y., Kwak Y.T., Xu S., Mercurio F., Barbosa M., Cobb M.H., Gaynor R.B. HTLV-I Tax Protein Binds to MEKK1 to Stimulate IkappaB Kinase Activity and NF-kappaB Activation. Cell 1998; 93: 875–884
   PubMed Web of Science ®Google Scholar
• Geleziunas R., Ferrell S., Lin X., Mu Y., Cunningham E.T., Grant M., Connelly M.A., Hambor J.E., Marcu K.B., Greene W.C. Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-kappaB Involves Activation of the IkappaB Kinase Alpha (IKKalpha) and IKKbeta Cellular Kinases. Mol. Cell Biol. 1998; 18: 5157–5165
   PubMed Web of Science ®Google Scholar
• Li X.H., Murphy K.M., Palka K.T., Surabhi R.M., Gaynor R.B. The Human T-Cell Leukemia Virus Type-1 Tax Protein Regulates the Activity of the IkappaB Kinase Complex. J. Biol. Chem. 1999; 274: 34417–34424
   PubMed Web of Science ®Google Scholar
• Hecht J.L., Aster J.C. Molecular Biology of Burkitt's Lymphoma. J. Clin. Oncol. 2000; 18: 3707–3721
   PubMed Web of Science ®Google Scholar
• Pulvertaft J.V. A Study of Malignant Tumours in Nigeria by Short-Term Tissue Culture. J. Clin. Pathol. 1965; 18: 261–271
   PubMed Web of Science ®Google Scholar
• Magrath I.T., Pizzo P.A., Whang-Peng J., Douglass E.C., Alabaster O., Gerber P., Freeman C.B., Novikovs L. Characterization of Lymphoma-Derived Cell Lines: Comparison of Cell Lines Positive and Negative for Epstein–Barr Virus Nuclear Antigen. I. Physical, Cytogenetic, and Growth Characteristics. J. Natl Cancer Inst. 1980; 64: 465–476
   PubMed Web of Science ®Google Scholar
• Grogan T.M., Warnke R.A., Kaplan H.S. A Comparative Study of Burkitt's and Non-Burkitt's Undifferentiated Malignant Lymphoma: Immunologic, Cytochemical, Ultrastructural, Cytologic, Histopathologic, Clinical and Cell Culture Features. Cancer 1982; 49: 1817–1828
   PubMed Web of Science ®Google Scholar
• MacDonald I., Wang H., Grand R., Armitage R.J., Fanslow W.C., Gregory C.D., Gordon J. Transforming Growth Factor-Beta 1 Cooperates with Anti-immunoglobulin for the Induction of Apoptosis in Group I (Biopsy-Like) Burkitt Lymphoma Cell Lines. Blood 1996; 87: 1147–1154
   PubMed Web of Science ®Google Scholar
• Gregory C.D., Dive C., Henderson S., Smith C.A., Williams G.T., Gordon J., Rickinson A.B. Activation of Epstein–Barr Virus Latent Genes Protects Human B Cells from Death by Apoptosis. Nature 1991; 349: 612–614
   PubMed Web of Science ®Google Scholar
• Kaptein J.S., Lin C.K.E., Wang C.L., Nguyen T.T., Kalunta C.I., Park E., Chen F.S., Lad P.M. Anti-IgM-Mediated Regulation of c-myc and Its Possible Relationship to Apoptosis. J. Biol. Chem. 1996; 271: 18875–18884
   PubMed Web of Science ®Google Scholar
• Schattner E.J., Elkon K.B., Yoo D.H., Tumang J., Krammer P.H., Crow M.K., Friedman S.M. CD40 Ligation Induces Apo-1/Fas Expression on Human B Lymphocytes and Facilitates Apoptosis Through the Apo-1/Fas Pathway. J. Exp. Med. 1995; 182: 1557–1565
   PubMed Web of Science ®Google Scholar
• Schattner E.J., Mascarenhas J., Bishop J., Yoo D.H., Chadburn A., Crow M.K., Friedman S.M. CD4+ T-Cell Induction of Fas-Mediated Apoptosis in Burkitt's Lymphoma B Cells. Blood 1996; 88: 1375–1382
   PubMed Web of Science ®Google Scholar
• Lens S.M., Tesselaar K., den Drijver B.F., van Oers M.H., van Lier R.A. A Dual Role for Both CD40-Ligand and TNF-Alpha in Controlling Human B Cell Death. J. Immunol. 1996; 156: 507–514
   PubMed Web of Science ®Google Scholar
• An S., Knox K.A. Ligation of CD40 Rescues Ramos–Burkitt Lymphoma B Cells from Calcium Ionophore- and Antigen Receptor-Triggered Apoptosis by Inhibiting Activation of the Cysteine Protease CPP32/Yama and Cleavage of Its Substrate PARP. FEBS Lett. 1996; 386: 115–122
   PubMed Web of Science ®Google Scholar
• Alam M.K., Davison S., Siddiqui N., Norton J.D., Murphy J.J. Ectopic Expression of Bcl-2, But Not Bcl-xL Rescues Ramos B Cells from Fas-Mediated Apoptosis. Eur. J. Immunol. 1997; 27: 3485–3491
   PubMed Web of Science ®Google Scholar
• Swinnen L.J., Costanzo-Nordin M.R., Fisher S.G., O'Sullivan E.J., Johnson M.R., Heroux A.L., Dizikes G.J., Pifarre R., Fisher R.I. Increased Incidence of Lymphoproliferative Disorder After Immunosuppression with the Monoclonal Antibody OKT3 in Cardiac-Transplant Recipients. N. Engl. J. Med. 1990; 323: 1723–1728
   PubMed Web of Science ®Google Scholar
• Opelz G., Henderson R. Incidence of Non-Hodgkin Lymphoma in Kidney and Heart Transplant Recipients. Lancet 1993; 342: 1514–1516
   PubMed Web of Science ®Google Scholar
• Chadburn A., Chen J.M., Hsu D.T., Frizzera G., Cesarman E., Garrett T.J., Mears J.G., Zangwill S.D., Addonizio L.J., Michler R.E., Knowles D.M. The Morphologic and Molecular Genetic Categories of Posttransplantation Lymphoproliferative Disorders Are Clinically Relevant. Cancer 1998; 82: 1978–1987
   PubMed Web of Science ®Google Scholar
• Papadopoulos E.B., Ladanyi M., Emanuel D., Mackinnon S., Boulad F., Carabasi M.H., Castro-Malaspina H., Childs B.H., Gillio A.P., Small T.N., et al. Infusions of Donor Leukocytes to Treat Epstein–Barr Virus-Associated Lymphoproliferative Disorders After Allogeneic Bone Marrow Transplantation. N. Engl. J. Med. 1994; 330: 1185–1191
   PubMed Web of Science ®Google Scholar
• Rooney C.M., Smith C.A., Ng C.Y., Loftin S., Li C., Krance R.A., Brenner M.K., Heslop H.E. Use of Gene-Modified Virus-Specific T Lymphocytes to Control Epstein–Barr-Virus-Related Lymphoproliferation. Lancet 1995; 345: 9–13
   PubMed Web of Science ®Google Scholar
• Cesarman E., Chadburn A., Liu Y.F., Migliazza A., Dalla-Favera R., Knowles D.M. BCL-6 Gene Mutations in Posttransplantation Lymphoproliferative Disorders Predict Response to Therapy and Clinical Outcome. Blood 1998; 92: 2294–2302
   PubMed Web of Science ®Google Scholar
• Cesarman E., Chang Y., Moore P.S., Said J.W., Knowles D.M. Kaposi's Sarcoma-Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity-Based Lymphomas. N. Engl. J. Med. 1995; 332: 1186–1191
   PubMed Web of Science ®Google Scholar
• Keller S.A., Schattner E.J., Cesarman E. Inhibition of NF-kappaB Induces Apoptosis of KSHV-Infected Primary Effusion Lymphoma Cells. Blood 2000; 96: 2537–2542
   PubMed Web of Science ®Google Scholar
• Silvestri F., Baccarani M. Hepatitis C Virus-Related Lymphomas. Br. J. Haematol. 1997; 99: 475–480
   PubMed Web of Science ®Google Scholar
• Dammacco F., Gatti P., Sansonno D. Hepatitis C Virus Infection, Mixed Cryoglobulinemia, and Non-Hodgkin's Lymphoma: An Emerging Picture. Leuk. Lymphoma 1998; 31: 463–476
   PubMed Web of Science ®Google Scholar
• Zelenetz A.D., Chen T.T., Levy R. Clonal Expansion in Follicular Lymphoma Occurs Subsequent to Antigenic Selection. J. Exp. Med. 1992; 176: 1137–1148
   PubMed Web of Science ®Google Scholar
• Bahler D.W., Levy R. Clonal Evolution of a Follicular Lymphoma: Evidence for Antigen Selection. Proc. Natl Acad. Sci. USA 1992; 89: 6770–6774
   PubMed Web of Science ®Google Scholar
• Jain R., Roncella S., Hashimoto S., Carbone A., Francia di Celle P., Foa R., Ferrarini M., Chiorazzi N. A Potential Role for Antigen Selection in the Clonal Evolution of Burkitt's Lymphoma. J. Immunol. 1994; 153: 45–52
   PubMed Web of Science ®Google Scholar
• Tamaru J., Hummel M., Marafioti T., Kalvelage B., Leoncini L., Minacci C., Tosi P., Wright D., Stein H. Burkitt's Lymphomas Express VH Genes with a Moderate Number of Antigen-Selected Somatic Mutations. Am. J. Pathol. 1995; 147: 1398–1407
   PubMed Web of Science ®Google Scholar
• Ottensmeier C.H., Thompsett A.R., Zhu D., Wilkins B.S., Sweetenham J.W., Stevenson F.K. Analysis of VH Genes in Follicular and Diffuse Lymphoma Shows Ongoing Somatic Mutation and Multiple Isotype Transcripts in Early Disease with Changes During Disease Progression. Blood 1998; 91: 4292–4299
   PubMed Web of Science ®Google Scholar
• Borche L., Lim A., Binet J.L., Dighiero G. Evidence that Chronic Lymphocytic Leukemia B Lymphocytes Are Frequently Committed to Production of Natural Autoantibodies. Blood 1990; 76: 562–569
   PubMed Web of Science ®Google Scholar
• Kipps T.J., Carson D.A. Autoantibodies in Chronic Lymphocytic Leukemia and Related Systemic Autoimmune Diseases. Blood 1993; 81: 2475–2487
   PubMed Web of Science ®Google Scholar
• Riboldi P., Gaidano G., Schettino E.W., Steger T.G., Knowles D.M., Dalla-Favera R., Casali P. Two Acquired Immunodeficiency Syndrome-Associated Burkitt's Lymphomas Produce Specific Anti-i IgM Cold Agglutinins Using Somatically Mutated VH4-21 Segments. Blood 1994; 83: 2952–2961
   PubMed Web of Science ®Google Scholar
• Roncella S., Cutrona G., Favre A., Ulivi M., Fais F., Signorini A., Grossi C.E., Chiorazzi N., Ferrarini M. Apoptosis of Burkitt's Lymphoma Cells Induced by Specific Interaction of Surface IgM with a Self-Antigen: Implications for Lymphomagenesis in Acquired Immunodeficiency Syndrome. Blood 1996; 88: 599–608
   PubMed Web of Science ®Google Scholar
• Lo Coco F., Gaidano G., Louie D.C., Offit K., Chaganti R.S., Dalla-Favera R. p53 Mutations Are Associated with Histologic Transformation of Follicular Lymphoma. Blood 1993; 82: 2289–2295
   PubMed Web of Science ®Google Scholar
• Sander C.A., Yano T., Clark H.M., Harris C., Longo D.L., Jaffe E.S., Raffeld M. p53 Mutation Is Associated with Progression in Follicular Lymphomas. Blood 1993; 82: 1994–2004
   PubMed Web of Science ®Google Scholar
• Elenitoba-Johnson K.S.J., Gascoyne R.D., Lim M.S., Chhanabai M., Jaffe E.S., Raffeld M. Homozygous Deletions at Chromosome 9p21 Involving p16 and p15 Are Associated with Histologic Progression in Follicle Center Lymphoma. Blood 1998; 91: 4677–4685
   PubMed Web of Science ®Google Scholar
• Wotherspoon A.C., Doglioni C., Diss T.C., Pan L., Moschini A., de Boni M., Isaacson P.G. Regression of Primary Low-Grade B-Cell Gastric Lymphoma of Mucosa-Associated Lymphoid Tissue Type After Eradication of Helicobacter pylori. Lancet 1993; 342: 575–577
   PubMed Web of Science ®Google Scholar
• Bayerdorffer E., Neubauer A., Rudolph B., Thiede C., Lehn N., Eidt S., Stolte M. Regression of Primary Gastric Lymphoma of Mucosa-Associated Lymphoid Tissue Type After Cure of Helicobacter pylori Infection. MALT Lymphoma Study Group. Lancet 1995; 345: 1591–1594
   PubMed Web of Science ®Google Scholar
• Hussell T., Isaacson P.G., Crabtree J.E., Dogan A., Spencer J. Immunoglobulin Specificity of Low Grade B Cell Gastrointestinal Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT) Type. Am. J. Pathol. 1993; 142: 285–292
   PubMed Web of Science ®Google Scholar
• Du M., Diss T.C., Xu C., Peng H., Isaacson P.G., Pan L. Ongoing Mutation in MALT Lymphoma Immunoglobulin Gene Suggests That Antigen Stimulation Plays a Role in the Clonal Expansion. Leukemia 1996; 10: 1190–1197
   PubMed Web of Science ®Google Scholar
• Hussell T., Isaacson P.G., Crabtree J.E., Spencer J. Helicobacter pylori-Specific Tumour-Infiltrating T Cells Provide Contact Dependent Help for the Growth of Malignant B Cells in Low-Grade Gastric Lymphoma of Mucosa-Associated Lymphoid Tissue. J. Pathol. 1996; 178: 122–127
   PubMed Web of Science ®Google Scholar
• Wright D.H. Burkitt's Lymphoma: A Review of the Pathology, Immunology, and Possible Etiologic Factors. Pathol. Annu. 1971; 6: 337–363
   PubMedGoogle Scholar
• Schattner E., Friedman S.M. Fas Expression and Apoptosis in Human B Cells. Immunol. Res. 1996; 15: 246–257
   PubMed Web of Science ®Google Scholar