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Research Article

Synthesis and Enzymatic Degradation of Epichlorohydrin Cross-Linked Pectins

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Pages 203-213 | Published online: 26 Feb 2003

References

  • May C.D. Industrial pectins: sources, production and applications. Carbohydr. Polym. 1990; 12: 79–99
  • Cummings J.H., Southgate D.A.T., Branch W.J., Wiggins H.S., Houston H., Jenkins D.J.A., Jivraj T., Hill M.J. The digestion of pectin in the human gut and its effect on calcium absorption and large bowel function. Br. J. Nutr. 1979; 41: 477–485
  • Watts P.J., Illum L. Colonic drug delivery. Drug Dev. Ind. Pharm. 1997; 23(9)893–913
  • Ashford M., Fell J., Attwood D., Sharma H., Woodhead P. An evaluation of pectin as carrier for drug targeting to the colon. J. Control. Rel. 1993; 26: 213–220
  • Ashford M., Fell J., Attwood D., Sharma H., Woodhead P. Studies on pectin formulations for colonic drug delivery. J. Control. Rel. 1994; 30: 225–232
  • Rubinstein A., Radai R., Ezra M., Pathak S., Rokem J.S. In vitro evaluation of calcium pectinate: a potential colon-specific drug delivery carrier. Pharm. Res. 1993; 10(2)258–263
  • Rubinstein A., Radai R. In vitro and in vivo analysis of colon specificity of calcium pectinate formulations. Eur. J. Pharm. Biopharm. 1995; 41(5)291–295
  • Wakerly Z., Fell J.T., Attwood D., Parkins D. Pectin/ethylcellulose film coating formulations for colonic drug delivery. Pharm. Res. 1996; 13(8)1210–1212
  • Wakerly Z., Fell J.T., Attwood D., Parkins D. Studies on drug release from Pectin/ethylcellulose film-coated tablets: a potential colonic delivery system. Int. J. Pharm. 1997; 153: 219–224
  • Macleod G.S., Fell J.T., Collett J.H. Studies on the physical properties of mixed pectin/ ethylcellulose films intended for colonic drug delivery. Int. J. Pharm. 1997; 157: 53–60
  • Semdé R., Amighi K., Pierre D., Devleeschouwer M.J., Moës A.J. Leaching of pectin from mixed pectin/insoluble polymer films intended for colonic drug delivery. Int. J. Pharm. 1998; 174: 233–241
  • Semdé R., Amighi K., Devleeschouwer M.J., Moës A.J. In vitro evaluation of pectin HM/ethylcellulose compression-coated formulations intended for colonic drug delivery. STP Pharma. Sci. 1999; 9(6)561–565
  • Semdé R., Amighi K., Devleeschouwer M.J., Moës A.J. Effect of pectinolytic enzymes on the theophylline release from pellets coated with water insoluble polymers containing pectin HM or calcium pectinate. Int. J. Pharm. 2000a; 197(1–2)169–179
  • Semdé R., Amighi K., Devleeschouwer M.J., Moës A.J. Studies of Pectin HM/Eudragit® RL/Eudragit® NE film-coating formulations intended for colonic drug delivery. Int. J. Pharm. 2000b; 197(1–2)181–192
  • Rombouts F.M., Wissenburg A.K., Pilnik W. Chromatographic separation of orange pectinesterase isoenzymes on pectates with different degrees of cross-linking. J. Chromatogr. 1979; 168: 151–161
  • Albersheim P., Neukom H., Deuel H. Splitting of pectin chain molecules in neutral solutions. Arch. Biochem. Biophys. 1960; 90: 46–51
  • US Pharmacopeia XXIII. US Pharmacopeial Convention. Rockville, MD 1995; 1161–1162
  • Heri W., Neukom H., Deuel H. Chromatographie von pecktinen mit verscheidener verteilung der methylester-gruppen auf den fadenmolekeln. Helv. Chim. Acta 1961; 44: 1945–1949
  • Wieland O. Glycerol UV-method. Methods of Enzymatic Analysis, 2nd Ed., Hans Ulrich, Bergmeyer, Karlfried, Gawehn. Academic Press, Inc., New York 1974; Vol. 3: 1404–1414
  • Renard E., Deratani A., Volet G., Seville B. Preparation and characterization of water soluble high molecular weight β-cyclodextrin-epichlorohydrin polymers. Eur. Polym. J. 1997; 33(1)49–57
  • Nelson N. A photometric adaptation of the Somogyi method for the determination of glucose. J. Biol. Chem. 1944; 375–380
  • Rexova-Benkova L. On the character of the interaction of endopolygalacturonase with cross-linked pectic acid. Biochim. Biophys. Acta 1972a; 276: 215–220
  • Rexova-Benkova L., Tibenski V. Selective purification of Aspergillus niger endopolygalacturonase by affinity chromatography on cross-linked pectic acid. Biochim. Biophys. Acta. 1972b; 268: 187–193
  • Chebli C., Cartilier L. Cross-linked cellulose as tablets excipient. A binding/disintegrating agent. Int. J. Pharm. 1998; 171: 101–110
  • Lenaerts V., Moussa I., Dumoulin Y., Mebsout F., Chouinard F., Szabo P., Mateescu M.A., Cartilier L., Marchessault R. Cross-linked high amylose starch for controlled release of drugs: recent advances. J. Control. Rel. 1998; 53: 225–234
  • Semdé R. Etude des pectines en vue de leur utilisation pour la délivrance spécifique des médicaments dans le côlon après administration orale. Université Libre de Bruxelles. 1999, Thesis
  • Simosen L., Hovgaard L., Mortensen P.B., Brondsted H. Dextran hydrogels for colon-specific drug delivery. V. Degradation in human intestinal incubation models. Eur. J. Pharm. Sci. 1995; 3: 329–337
  • Vervoort L., Rombaut P., Van den Mooter G., Augustijns P., Kinget R. Inulin hydrogels. II. In vitro degradation study. Int. J. Pharm. 1998; 172: 137–145
  • Semdé R., Moës A.J., Devleeschouwer M.J., Amighi K. In vitro evaluation of epichlorohydrin cross-linked pectins as colon-specific drug delivery carriers. STP Pharma. Sci. 2002; 12: 293–298

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