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Research Article

Characterization of the Mechanism of Interaction in Ibuprofen‐Eudragit RL100® Coevaporates

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Pages 277-288 | Published online: 03 Nov 2004

References

  • Ford J. L. The current status of solid dispersions. Pharm. Acta Helv. 1986; 61: 69–87
  • Kislalioglu M. S., Khan M. A., Blount C., Goettsh R. W., Bolton S. Physical characterization and dissolution properties of ibuprofen: Eudragit coprecipitates. J. Pharm. Sci. 1981; 80: 799–804
  • Beten D. B., Moes A. J. Controlled‐release coevaporates of dipyridamole prepared with acrylic polymers. Int. J. Pharm. 1994; 103: 243–251
  • Karnachi A. A., De Hon R. A., Khan M. A. Compression of indomethacin coprecipitates with polymer mixtures: effect of preparation methodology. Drug Dev. Ind. Pharm. 1995; 21: 1473–1483
  • Khan M. A., Dib J., Reddy I. K. Statistical optimization of ketoprofen‐Eudragit S100 coprecipitates to obtain controlled‐release tablets. Drug Dev. Ind. Pharm. 1996; 22: 135–141
  • Benita S., Hoffman A., Donbrow M. Microencapsulation of paracetamol using polyacrylate resins (Eudragit Retard), kinetics of drug release and evaluation of kinetic model. J. Pharm. Pharmacol. 1985; 37: 391–395
  • Goto S., Kawata M., Nakamura M., Maekauwa K., Ayoama T. Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. J. Microencapsul 1986; 3: 293–304
  • Kawata M., Nakamura M., Goto T., Ayoama T. Preparation and dissolution pattern of Eudragit RS microcapsules containing Ketoprofen. Chem. Pharm. Bull. 1986; 34: 2618–2623
  • Kawashima Y., Iwamoto T., Niwa T., Takeuchi H., Hino T. Size control of ibuprofen microspheres with an acrylic polymer by changing the pH in an aqueous dispersion medium and its mechanism. Chem. Pharm. Bull. 1993; 41: 191–195
  • Murthy T. E.G.K., Verma P. R.P. Controlled transdermal delivery of flurbiprofen films using mixed grades of Eudragit: design, in‐vitro and in‐vivo evaluation. Int. J. Pharm. Adv. 1996; 1: 391–397
  • Pignatello R., Vandelli M. A., Giunchedi P., Puglisi G. Properties of tolmetin‐loaded Eudragit® RL100 and RS100 microparticles prepared by different techniques. STP Pharma Sci. 1997; 7: 148–157
  • Pignatello R., Ferro M., De Guidi G., Salemi G., Vandelli M. A., Guccione S., Geppi M., Forte C., Puglisi G. Preparation, characterisation and photosensitivity studies of solid dispersions of diflunisal and Eudragit RS100 and RL100. Int. J. Pharm. 2001; 218: 27–42
  • Pignatello R., Amico D., Chiechio S., Spadaro C., Puglisi G., Giunchedi P. Preparation and analgesic activity of Eudragit® RS100 microparticles containing diflunisal. Drug Deliv. 2001; 8: 35–45
  • Pignatello R., Spedalieri G., Bucolo C., Maltese A., Puglisi G. Flurbiprofen‐loaded acrylate polymer nanosuspensions for ophthalmic application. Biomaterials 2002; 23: 3247–3255, [CSA]
  • Valle‐Jones J. C., Smith J., Rowley‐Jones D. A comparison in general practice of once and twice daily sustained‐release ibuprofen and standard ibuprofen in the treatment of non‐articular rheumatism. Br. J. Clin. Pract. 1984; 38: 353–358
  • Kawashima Y., Niwa T., Handa T., Takeuchi H., Iwamoto T., Itoh K. Preparation of controlled‐release microspheres of ibuprofen with acrylic polymers by a novel quasi‐emulsion solvent diffusion method. J. Pharm. Sci. 1989; 78: 68–72
  • Dubernet C., Rouland J. C., Benoit J. P. Ibuprofen‐loaded ethylcellulose microspheres: analysis of the matrix structure by thermal analysis. J. Pharm. Sci. 1991; 80: 1029–1033
  • Kawashima Y., Niwa T., Takeuchi H., Hino T., Ito Y. Control of prolonged drug release and compression properties of ibuprofen microsponges with acrylic polymer, Eudragit RS, by changing their intraparticle porosity. Chem. Pharm. Bull. 1992; 40: 196–201
  • Bodmeier R., Wang J. Microencapsulation of drugs with aqueous colloidal polymer dispersions. J. Pharm. Sci. 1993; 82: 191–194
  • Theis D. L., Lucisano L. J., Halstead G. W. Use of stable isotopes for evaluation of drug delivery systems: comparison of ibuprofen release in vivo and in vivo from two biphasic release formulations utilizing different rate‐controlling polymers. Pharm. Res. 1994; 11: 1069–1076
  • Palmieri G. F., Lovato D., Martelli S. New controlled‐release ibuprofen tablets. Drug Dev. Ind. Pharm. 1999; 25: 671–677, [CSA]
  • Kachrimanis K., Nikolakakis I., Malamataris S. Spherical crystal agglomeration of ibuprofen by the solvent‐change technique in presence of methacrylic polymers. J. Pharm. Sci. 2000; 89: 250–259
  • Perumal D. Microencapsulation of ibuprofen and Eudragit RS 100 by the emulsion solvent diffusion technique. Int. J. Pharm. 2001; 218: 1–11
  • Kidokoro M., Shah N. H., Malick A. W., Infeld M. H., McGinity J. W. Properties of tablets containing granulations of ibuprofen and an acrylic copolymer prepared by thermal processes. Pharm. Dev. Technol. 2001; 6: 263–275, [CSA]
  • Oth M. P., Moes A. J. Sustained release solid dispersions of indomethacin with Eudragit RS and RL. Int. J. Pharm. 1989; 55: 157–164
  • Jenquin M. R., Liebowitz S. M., Sarabia R. E., McGinity J. W. Physical and chemical factors influencing the release of drugs from acrylic resin films. J. Pharm. Sci. 1990; 79: 811–816
  • Pignatello R., Ferro M., Puglisi G. Preparation of solid dispersions of non‐steroidal anti‐inflammatory drugs with acrylic polymers and studies on mechanisms of drug‐polymer interactions. AAPS PharmSciTech 2002; 3, art. 10

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