48
Views
13
CrossRef citations to date
0
Altmetric
Research Article

RESTORATION OF IMMUNOCYTE FUNCTIONS BY THYMOSIN α1 IN CYCLOPHOSPHAMIDE-INDUCED IMMUNODEFICIENT MICE

, , , , &
Pages 75-82 | Published online: 04 Feb 2001

REFERENCES

  • Goldstein A. L., Low T. L. K., Adoo M., Mcclure L., Thurman G. B., Rossio G., La C. Y., Chang D., Wang S. S., Harwey C., Ramel A. H., Meienhofer J. Thymosin alpha 1. Isolation and sequence analysis of an immunologically active thymic polypeptide. Proc. Natl. Acad. Sci. USA 1977; 74: 725
  • Favalli C., Jezzi T., Mastino A., Rinaldi-Garaci C., Riccardi C., Garaci E. Modulation of natural killer activity by thymosin α1 and interferon. Cancer Immunol. Immunother. 1985; 20: 189
  • Serrate S. A., Schulof R. S., Leonardis L., Goldstein A. L., Sztein M. B. Modulation of human natural killer cell cytotoxic activity, lymphokine production, and interleukin 2 receptor expression by thymic hormones. J. Immunol. 1987; 139: 2338
  • Zazt M. M., Oliver J., Samuels C., Skotnicki A. B., Sztein M. B., Goldstein A. L. Thymosin increases production of T cell growth factor by normal human peripheral blood lymphocytes. Proc. Natl. Acad. Sci. USA 1985; 81: 2882
  • Cordero O. J., Sarandeses C. S., Lopez J. L., Cancio E., Reguerio B. J., Nogueria M. Prothymosin alpha 1 enhances interleukin-2 receptor expression in normal T-lymphocytes. Int. J. Immunopharmacol. 1991; 13: 1059
  • D'Agostini C., Palamara A. T., Favalli C., Silvilia M., Febbraio G., Bué C., Garaci E. Efficacy of combination therapy with amantadine, thymosin α1 and α/β interferon in mice infected with influenza A virus. Int. J. Immunopharmacol. 1996; 18: 96
  • Garaci E., Mastino A., Pica F., Favalli C. Combination treatment using thymosin α1 and interferon after cyclophosphamide is able to cure Lewis lung carcinoma in mice. Cancer Immunol. Immunother. 1990; 32: 154
  • Garaci E., Bonsignore G., Della Giulia M., D'Aprile M., Favalli C., Rasi G., Santini S., Capomolla E., Vici P., Di Lauro L. Sequential chemoimmunotherapy for advanced nonsmall cell lung cancer using cisplatin, etoposide, thymosin-α1 and interferon-α2. Eur. J. Cancer 1995; 31a: 2404
  • Mutchinick M. G., Appleman H. D., Chung H. T., Aragona E., Gupta T. P., Cummings G. D., Waggoner J. G., Hoofnagle J. H., Shafritz D. A. Thymosin treatment of chronic hepatitis B: a placebo controlled trial. Hepatology 1991; 14: 409
  • Rasi G., Mutchnick M. G., Di Virgilio D., Sinibaldi-Vallebona P., Pierimarchi P., Colella F., Favalli C., Garaci E. Combination low-dose lymphoblastoid interferon and thymosin α1 therapy in the treatment of chronic hepatitis B. J. Viral Hepat. 1996; 3: 191
  • Rasi G., Di Virgilio D., Mutchnick M. G., Colella F., Sinibaldi-Vallebona P., Pierimarchi P., Valli B., Garaci E. Combination thymosin α1 and lymphoblastoid interferon treatment in chronic hepatitis C. Gut 1996; 39: 679
  • Hikida M., Takai T., Ohmori H. Requirements of a costimulus for IL-4-induced IgE class switching murine B cells activated via antigen receptors. J. Immunol. 1996; 156: 2730
  • Ohmori H., Hikida M., Takai T. Prostaglandin E2 as a selective stimulator of antigen-specific IgE response in murine lymphocytes. Eur. J. Immunol. 1990; 20: 2499
  • Ohmori H., Takai T., Tanigawa T., Honma Y. Establishment of an enzyme release assay for cytotoxic T lymphocyte activity. J. Immunol. Methods 1992; 147: 119
  • Ohta Y., Sueki K., Yoneyama Y., Tezuka E., Yagi Y. Immunomodulating activity of thymosin fraction 5 and thymosin α1 in immunosuppressed mice. Cancer Immunol. Immunother. 1983; 15: 108
  • Frasca D., Adorini L., Doria G. Enhancement of Helper and suppressor T cell activities by thymosin α1 injection in old mice. Immunopharmacol. 1985; 10: 41
  • Frasca D., Adorini L., Doria G. Enhanced frequency of mitogen-responsive T cell precursors in old mice injected with thymosin α1. Eur. J. Immunol. 1987; 17: 727
  • Ishitsuka H., Umeda Y., Nakamura J., Yagi Y. Protective activity of thymosin against opportunistic infections in animal models. Cancer Immunol. Immunother. 1983; 14: 145

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.