Membrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes

REFERENCES

• Boerth, N. J., J. J. Sadler, D. E. Bauer, J. L. Clements, S. M. Gheith, and G. A. Koretzky. 2000. Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling. J. Exp. Med. 192:1047–1058.
   PubMedGoogle Scholar
• Brown, D. A., and E. London. 2000. Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J. Biol. Chem. 275:17221–17224.
   PubMed Web of Science ®Google Scholar
• Chan, A. C., M. Dalton, R. Johnson, G. H. Kong, T. Wang, R. Thoma, and T. Kurosaki. 1995. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14:2499–2508.
   PubMed Web of Science ®Google Scholar
• Crabtree, G. R., and N. A. Clipstone. 1994. Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu. Rev. Biochem. 63:1045–1083.
   PubMed Web of Science ®Google Scholar
• DeBell, K. E., B. A. Stoica, M. C. Veri, A. Di Baldassarre, S. Miscia, L. J. Graham, B. L. Rellahan, M. Ishiai, T. Kurosaki, and E. Bonvini. 1999. Functional independence and interdependence of the src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction. Mol. Cell. Biol. 19:7388–7398.
   PubMedGoogle Scholar
• Debnath, J., M. Chamorro, M. J. Czar, E. M. Schaeffer, M. J. Lenardo, H. E. Varmus, and P. L. Schwartzberg. 1999. rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases. Mol. Cell. Biol. 19:1498–1507.
   PubMed Web of Science ®Google Scholar
• Denny, M. F., H. C. Kaufman, A. C. Chan, and D. B. Straus. 1999. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling. J. Biol. Chem. 274:5146–5152.
   PubMedGoogle Scholar
• Finco, T. S., T. Kadlecek, W. Zhang, L. E. Samelson, and A. Weiss. 1998. LAT is required for TCR-mediated activation of PLCgammal and the Ras pathway. Immunity 9:617–626.
   PubMed Web of Science ®Google Scholar
• Hanke, J. H., J. P. Gardner, R. L. Dow, P. S. Changelian, W. H. Brissette, E. J. Weringer, B. A. Pollok, and P. A. Connelly. 1996. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J. Biol. Chem. 271:695–701.
   PubMed Web of Science ®Google Scholar
• Jackman, J. K., D. G. Motto, Q. Sun, M. Tanemoto, C. W. Turck, G. A. Peltz, G. A. Koretzky, and P. R. Findell. 1995. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J. Biol. Chem. 270:7029–7032.
   PubMed Web of Science ®Google Scholar
• Janes, P. W., S. C. Ley, A. I. Magee, and P. S. Kabouridis. 2000. The role of lipid rafts in T cell antigen receptor (TCR) signalling. Semin. Immunol. 12:23–34.
   PubMed Web of Science ®Google Scholar
• Kabouridis, P. S., A. I. Magee, and S. C. Ley. 1997. S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. EMBO J 16:4983–4998.
   PubMed Web of Science ®Google Scholar
• Kane, L. P., J. Lin, and A. Weiss. 2000. Signal transduction by the TCR for antigen. Curr. Opin. Immunol. 12:242–249.
   PubMed Web of Science ®Google Scholar
• Kim, H. K., J. W. Kim, A. Zilberstein, B. Margolis, J. G. Kim, J. Schlessinger, and S. G. Rhee. 1991. PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. Cell 65:435–441.
   PubMed Web of Science ®Google Scholar
• Kong, G., M. Dalton, J. B. Wardenburg, D. Straus, T. Kurosaki, and A. C. Chan. 1996. Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function. Mol. Cell. Biol. 16:5026–5035.
   PubMed Web of Science ®Google Scholar
• Li, T., D. J. Rawlings, H. Park, R. M. Kato, O. N. Witte, and A. B. Satterthwaite. 1997. Constitutive membrane association potentiates activation of Bruton tyrosine kinase. Oncogene 15:1375–1383.
   PubMedGoogle Scholar
• Li, Z., M. I. Wahl, A. Eguinoa, L. R. Stephens, P. T. Hawkins, and O. N. Witte. 1997. Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases. Proc. Natl. Acad. Sci. USA 94:13820–13825.
   PubMedGoogle Scholar
• Liao, X. C., and D. R. Littman. 1995. Altered T cell receptor singaling and disrupted T cell development in mice lacking Itk. Immunity 3:757–769.
   PubMed Web of Science ®Google Scholar
• Lin, J., A. Weiss, and T. S. Finco. 1999. Localization of LAT in glycolipid-enriched microdomains is required for T cell activation. J. Biol. Chem. 274:28861–28864.
   PubMedGoogle Scholar
• Liu, K. Q., S. C. Bunnell, C. B. Gurniak, and L. J. Berg. 1998. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. J. Exp. Med. 187:1721–1727.
   PubMed Web of Science ®Google Scholar
• Liu, S. K., N. Fang, G. A. Koretzky, and C. J. McGlade. 1999. The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors. Curr. Biol. 9:67–75.
   PubMedGoogle Scholar
• Montixi, C., C. Langlet, A. M. Bernard, J. Thimonier, C. Dubois, M. A. Wurbel, J. P. Chauvin, M. Pierres, and H. T. He. 1998. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J. 17:5334–5348.
   PubMed Web of Science ®Google Scholar
• Nakanishi, O., F. Shibasaki, M. Hidaka, Y. Homma, and T. Takenawa. 1993. Phospholipase C-gamma 1 associates with viral and cellular src kinases. J. Biol. Chem. 268:10754–10759.
   PubMed Web of Science ®Google Scholar
• Orlandi, P. A., and P. H. Fishman. 1998. Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol. 141:905–915.
   PubMed Web of Science ®Google Scholar
• Rhee, S. G., and Y. S. Bae. 1997. Regulation of phosphoinositide-specific phospholipase C isozymes. J. Biol. Chem. 272:15045–15048.
   PubMed Web of Science ®Google Scholar
• Schaeffer, E. M., J. Debnath, G. Yap, D. McVicar, X. C. Liao, D. R. Littman, A. Sher, H. E. Varmus, M. J. Lenardo, and P. L. Schwartzberg. 1999. Requirement for Tec kinases R1k and Itk in T cell receptor signaling and immunity. Science 284:638–641.
   PubMed Web of Science ®Google Scholar
• Schaeffer, E. M., and P. L. Schwartzberg. 2000. Tec family kinases in lymphocyte signaling and function. Curr. Opin. Immunol. 12:282–288.
   PubMedGoogle Scholar
• Scharenberg, A. M., O. El-Hillal, D. A. Fruman, L. O. Beitz, Z. Li, S. Lin, I. Gout, L. C. Cantley, D. J. Rawlings, and J. P. Kinet. 1998. Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals. EMBO J. 17:1961–1972.
   PubMedGoogle Scholar
• Shan, X., M. J. Czar, S. C. Bunnell, P. Liu, Y. Liu, P. L. Schwartzberg, and R. L. Wange. 2000. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol. Cell. Biol. 20:6945–6957.
   PubMed Web of Science ®Google Scholar
• Shan, X., and R. L. Wange. 1999. Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment. J. Biol. Chem. 274:29323–29330.
   PubMed Web of Science ®Google Scholar
• Shenoy-Scaria, A. M., D. J. Dietzen, J. Kwong, D. C. Link, and D. M. Lublin. 1994. Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae. J. Cell Biol. 126:353–363.
   PubMed Web of Science ®Google Scholar
• Simons, K., and E. Ikonen. 1997. Functional rafts in cell membranes. Nature 387:569–572.
   PubMed Web of Science ®Google Scholar
• Stoica, B., K. E. DeBell, L. Graham, B. L. Rellahan, M. A. Alava, J. Laborda, and E. Bonvini. 1998. The amino-terminal Src homology 2 domain of phospholipase C gamma 1 is essential for TCR-induced tyrosine phosphorylation of phospholipase C gamma 1. J. Immunol. 160:1059–1066.
   PubMedGoogle Scholar
• Straus, D. B., and A. Weiss. 1992. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70:585–593.
   PubMed Web of Science ®Google Scholar
• Su, Y. W., Y. Zhang, J. Schweikert, G. A. Koretzky, M. Reth, and J. Wienands. 1999. Interaction of SLP adaptors with the SH2 domain of Tec family kinases. Eur. J. Immunol. 29:3702–3711.
   PubMed Web of Science ®Google Scholar
• Towler, D. A., J. I. Gordon, S. P. Adams, and L. Glaser. 1988. The biology and enzymology of eukaryotic protein acylation. Annu. Rev. Biochem. 57:69–99.
   PubMed Web of Science ®Google Scholar
• Wange, R. L., R. Guitian, N. Isakov, J. D. Watts, R. Aebersold, and L. E. Samelson. 1995. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J. Biol. Chem. 270:18730–18733.
   PubMed Web of Science ®Google Scholar
• Wardenburg, J. B., C. Fu, J. K. Jackman, H. Flotow, S. E. Wilkinson, D. H. Williams, R. Johnson, G. Kong, A. C. Chan, and P. R. Findell. 1996. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J. Biol. Chem. 271:19641–19644.
   PubMedGoogle Scholar
• Weiss, A., G. Koretzky, R. C. Schatzman, and T. Kadlecek. 1991. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proc. Natl. Acad. Sci. USA 88:5484–5488.
   PubMedGoogle Scholar
• Williams, B. L., K. L. Schreiber, W. Zhang, R. L. Wange, L. E. Samelson, P. J. Leibson, and R. T. Abraham. 1998. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol. Cell. Biol. 18:1388–1399.
   PubMedGoogle Scholar
• Wolven, A., H. Okamura, Y. Rosenblatt, and M. D. Resh. 1997. Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association. Mol. Biol. Cell 8:1159–1173.
   PubMed Web of Science ®Google Scholar
• Xavier, R., T. Brennan, Q. Li, C. McCormack, and B. Seed. 1998. Membrane compartmentation is required for efficient T cell activation. Immunity 8:723–732.
   PubMed Web of Science ®Google Scholar
• Yablonski, D., M. R. Kuhne, T. Kadlecek, and A. Weiss. 1998. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science 281:413–416.
   PubMedGoogle Scholar
• Yamasaki, S., M. Takamatsu, and M. Iwashima. 1996. The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization. Mol. Cell. Biol. 16:7151–7160.
   PubMedGoogle Scholar
• Yoder, J., C. Pham, Y. M. Iizuka, O. Kanagawa, S. K. Liu, J. McGlade, and A. M. Cheng. 2001. Requirement for the SLP-76 adaptor GADS in T cell development. Science 291:1987–1991.
   PubMedGoogle Scholar
• Zhang, W., B. J. Irvin, R. P. Trible, R. T. Abraham, and L. E. Samelson. 1999. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. Int. Immunol. 11:943–950.
   PubMed Web of Science ®Google Scholar
• Zhang, W., J. Sloan-Lancaster, J. Kitchen, R. P. Trible, and L. E. Samelson. 1998. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:83–92.
   PubMed Web of Science ®Google Scholar
• Zhang, W., R. P. Trible, and L. E. Samelson. 1998. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 9:239–246.
   PubMed Web of Science ®Google Scholar
• Zhang, W., R. P. Trible, M. Zhu, S. K. Liu, C. J. McGlade, and L. E. Samelson. 2000. Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J. Biol. Chem. 275:23355–23361.
   PubMed Web of Science ®Google Scholar