Molecular and Cellular Biology, Volume 21, Issue 20 (2001)

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Molecular and Cellular Biology, Volume 21, Issue 20 (2001)

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Cell Growth and Development

Article
The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis
Baharia Mograbi, Renata Bocciardi, Isabelle Bourget, Thierry Juhel, Dariush Farahi-Far, Giovanni Romeo, Isabella Ceccherini & Bernard Rossi
Pages: 6719-6730
Published online: 27 Mar 2023
AbstractforThe Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis | Full Text | References | PDF (615.4 KB)
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Article
The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells
Alo Nag, Tanya Bondar, Shalu Shiv & Pradip Raychaudhuri
Pages: 6738-6747
Published online: 27 Mar 2023
AbstractforThe Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells | Full Text | References | PDF (290.4 KB)
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Article
Role of p14ARF in Replicative and Induced Senescence of Human Fibroblasts
Wenyi Wei, Ruth M. Hemmer & John M. Sedivy
Pages: 6748-6757
Published online: 27 Mar 2023
AbstractforRole of p14ARF in Replicative and Induced Senescence of Human Fibroblasts | Full Text | References | PDF (307.1 KB)
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Article
Down-Regulation of β-Catenin by Activated p53
Einat Sadot, Benjamin Geiger, Moshe Oren & Avri Ben-Ze'ev
Pages: 6768-6781
Published online: 27 Mar 2023
AbstractforDown-Regulation of β-Catenin by Activated p53 | Full Text | References | PDF (1.1 MB)
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Article
Involvement of Alpha-PAK-Interacting Exchange Factor in the PAK1–c-Jun NH2-Terminal Kinase 1 Activation and Apoptosis Induced by Benzo[a]pyrene
Shigeto Yoshii, Masamitsu Tanaka, Yoshiro Otsuki, Toshiharu Fujiyama, Hideki Kataoka, Hajime Arai, Hiroyuki Hanai & Haruhiko Sugimura
Pages: 6796-6807
Published online: 27 Mar 2023
AbstractforInvolvement of Alpha-PAK-Interacting Exchange Factor in the PAK1–c-Jun NH2-Terminal Kinase 1 Activation and Apoptosis Induced by Benzo[a]pyrene | Full Text | References | PDF (431.2 KB)
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Article
Growth Arrest and DNA Damage-Inducible Protein GADD34 Assembles a Novel Signaling Complex Containing Protein Phosphatase 1 and Inhibitor 1
John H. Connor, Douglas C. Weiser, Shi Li, John M. Hallenbeck & Shirish Shenolikar
Pages: 6841-6850
Published online: 27 Mar 2023
AbstractforGrowth Arrest and DNA Damage-Inducible Protein GADD34 Assembles a Novel Signaling Complex Containing Protein Phosphatase 1 and Inhibitor 1 | Full Text | References | PDF (283 KB)
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Article
Expression of Gab1 Lacking the Pleckstrin Homology Domain Is Associated with Neoplastic Progression
Hideto Kameda, John I. Risinger, Bing-Bing Han, Seung Joon Baek, J. Carl Barrett, Tohru Abe, Tsutomu Takeuchi, Wayne C. Glasgow & Thomas E. Eling
Pages: 6895-6905
Published online: 27 Mar 2023
AbstractforExpression of Gab1 Lacking the Pleckstrin Homology Domain Is Associated with Neoplastic Progression | Full Text | References | PDF (356.4 KB)
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Article
Enhanced ROS Production in Oncogenically Transformed Cells Potentiates c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Activation and Sensitization to Genotoxic Stress
Moran Benhar, Idan Dalyot, David Engelberg & Alexander Levitzki
Pages: 6913-6926
Published online: 27 Mar 2023
AbstractforEnhanced ROS Production in Oncogenically Transformed Cells Potentiates c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Activation and Sensitization to Genotoxic Stress | Full Text | References | PDF (764.7 KB)
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Article
Molecular Basis for Impaired Muscle Differentiation in Myotonic Dystrophy
Nikolai A. Timchenko, Polina Iakova, Zong-Jin Cai, James R. Smith & Lubov T. Timchenko
Pages: 6927-6938
Published online: 27 Mar 2023
AbstractforMolecular Basis for Impaired Muscle Differentiation in Myotonic Dystrophy | Full Text | References | PDF (876.5 KB)
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Article
Membrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes
Maria-Concetta Verı́, Karen E. DeBell, Maria-Cristina Seminario, Angela DiBaldassarre, Ilona Reischl, Rashmi Rawat, Laurie Graham, Cristiana Noviello, Barbara L. Rellahan, Sebastiano Miscia, Ronald L. Wange & Ezio Bonvini
Pages: 6939-6950
Published online: 27 Mar 2023
AbstractforMembrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes | Full Text | References | PDF (822.1 KB)
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Article
Saccharomyces cerevisiae Mob1p Is Required for Cytokinesis and Mitotic Exit
Francis C. Luca, Manali Mody, Cornelia Kurischko, David M. Roof, Thomas H. Giddings & Mark Winey
Pages: 6972-6983
Published online: 27 Mar 2023
AbstractforSaccharomyces cerevisiae Mob1p Is Required for Cytokinesis and Mitotic Exit | Full Text | References | PDF (1.1 MB)
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Article
A Novel Mitogen-Activated Protein Kinase Phosphatase Is an Important Negative Regulator of Lipopolysaccharide-Mediated c-Jun N-Terminal Kinase Activation in Mouse Macrophage Cell Lines
Tetsuya Matsuguchi, Tipayaratn Musikacharoen, Thomas R. Johnson, Andrew S. Kraft & Yasunobu Yoshikai
Pages: 6999-7009
Published online: 27 Mar 2023
AbstractforA Novel Mitogen-Activated Protein Kinase Phosphatase Is an Important Negative Regulator of Lipopolysaccharide-Mediated c-Jun N-Terminal Kinase Activation in Mouse Macrophage Cell Lines | Full Text | References | PDF (603 KB)
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Article
MSY2 and MSY4 Bind a Conserved Sequence in the 3′ Untranslated Region of Protamine 1 mRNA In Vitro and In Vivo
Flaviano Giorgini, Holly G. Davies & Robert E. Braun
Pages: 7010-7019
Published online: 27 Mar 2023
AbstractforMSY2 and MSY4 Bind a Conserved Sequence in the 3′ Untranslated Region of Protamine 1 mRNA In Vitro and In Vivo | Full Text | References | PDF (1.1 MB)
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Article
Induction of Distinct [URE3] Yeast Prion Strains
Martin Schlumpberger, Stanley B. Prusiner & Ira Herskowitz
Pages: 7035-7046
Published online: 27 Mar 2023
AbstractforInduction of Distinct [URE3] Yeast Prion Strains | Full Text | References | PDF (1,009.3 KB)
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Gene Expression

Article
cis Recognition Elements in Plant Mitochondrion RNA Editing
Jean-Claude Farré, Gabriel Leon, Xavier Jordana & Alejandro Araya
Pages: 6731-6737
Published online: 27 Mar 2023
Abstractforcis Recognition Elements in Plant Mitochondrion RNA Editing | Full Text | References | PDF (222.8 KB)
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Article
Four Related Proteins of the Trypanosoma brucei RNA Editing Complex
Aswini K. Panigrahi, Achim Schnaufer, Nicole Carmean, Robert P. Igo Jr., Steven P. Gygi, Nancy L. Ernst, Setareh S. Palazzo, David S. Weston, Ruedi Aebersold, Reza Salavati & Kenneth D. Stuart
Pages: 6833-6840
Published online: 27 Mar 2023
AbstractforFour Related Proteins of the Trypanosoma brucei RNA Editing Complex | Full Text | References | PDF (238.5 KB)
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Article
Versatile Role for hnRNP D Isoforms in the Differential Regulation of Cytoplasmic mRNA Turnover
Nianhua Xu, Chyi-Ying A. Chen & Ann-Bin Shyu
Pages: 6960-6971
Published online: 27 Mar 2023
AbstractforVersatile Role for hnRNP D Isoforms in the Differential Regulation of Cytoplasmic mRNA Turnover | Full Text | References | PDF (816.6 KB)
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Article
Hpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae
Sebastián Chávez, Marı́a Garcı́a-Rubio, Félix Prado & Andrés Aguilera
Pages: 7054-7064
Published online: 27 Mar 2023
AbstractforHpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae | Full Text | References | PDF (505.5 KB)
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Dna Dynamics and Chromosome Structure

Article
Asymmetric Processing of Human Immunodeficiency Virus Type 1 cDNA In Vivo: Implications for Functional End Coupling during the Chemical Steps of DNA Transposition
Hongmin Chen & Alan Engelman
Pages: 6758-6767
Published online: 27 Mar 2023
AbstractforAsymmetric Processing of Human Immunodeficiency Virus Type 1 cDNA In Vivo: Implications for Functional End Coupling during the Chemical Steps of DNA Transposition | Full Text | References | PDF (238.3 KB)
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Article
Novel Meiosis-Specific Isoform of Mammalian SMC1
E. Revenkova, M. Eijpe, C. Heyting, B. Gross & R. Jessberger
Pages: 6984-6998
Published online: 27 Mar 2023
AbstractforNovel Meiosis-Specific Isoform of Mammalian SMC1 | Full Text | References | PDF (1.3 MB)
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Transcriptional Regulation

Article
Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo
Ernest Martinez, Vikas B. Palhan, Agneta Tjernberg, Elena S. Lymar, Armin M. Gamper, Tapas K. Kundu, Brian T. Chait & Robert G. Roeder
Pages: 6782-6795
Published online: 27 Mar 2023
AbstractforHuman STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo | Full Text | References | PDF (617.8 KB)
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Article
Developmental and Transcriptional Consequences of Mutations in Drosophila TAFII60
Norikazu Aoyagi & David A. Wassarman
Pages: 6808-6819
Published online: 27 Mar 2023
AbstractforDevelopmental and Transcriptional Consequences of Mutations in Drosophila TAFII60 | Full Text | References | PDF (1 MB)
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Article
Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters
Amy S. Weinmann, Stephanie M. Bartley, Theresa Zhang, Michael Q. Zhang & Peggy J. Farnham
Pages: 6820-6832
Published online: 27 Mar 2023
AbstractforUse of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters | Full Text | References | PDF (356.2 KB)
  • 49 Views
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Article
Differential Interactions of Specific Nuclear Factor I Isoforms with the Glucocorticoid Receptor and STAT5 in the Cooperative Regulation of WAP Gene Transcription
Sudit S. Mukhopadhyay, Shannon L. Wyszomierski, Richard M. Gronostajski & Jeffrey M. Rosen
Pages: 6859-6869
Published online: 27 Mar 2023
AbstractforDifferential Interactions of Specific Nuclear Factor I Isoforms with the Glucocorticoid Receptor and STAT5 in the Cooperative Regulation of WAP Gene Transcription | Full Text | References | PDF (1.2 MB)
  • 7 Views
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Article
Widespread Use of TATA Elements in the Core Promoters for RNA Polymerases III, II, and I in Fission Yeast
Mitsuhiro Hamada, Ying Huang, Todd M. Lowe & Richard J. Maraia
Pages: 6870-6881
Published online: 27 Mar 2023
AbstractforWidespread Use of TATA Elements in the Core Promoters for RNA Polymerases III, II, and I in Fission Yeast | Full Text | References | PDF (474.2 KB)
  • 29 Views
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Article
Positive and Negative TAFII Functions That Suggest a Dynamic TFIID Structure and Elicit Synergy with TRAPs in Activator-Induced Transcription
Mohamed Guermah, Yong Tao & Robert G. Roeder
Pages: 6882-6894
Published online: 27 Mar 2023
AbstractforPositive and Negative TAFII Functions That Suggest a Dynamic TFIID Structure and Elicit Synergy with TRAPs in Activator-Induced Transcription | Full Text | References | PDF (431.4 KB)
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Article
The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression
Brian P. Ashburner, Sandy D. Westerheide & Albert S. Baldwin Jr.
Pages: 7065-7077
Published online: 27 Mar 2023
AbstractforThe p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression | Full Text | References | PDF (444.8 KB)
  • 136 Views
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Article
A 36-Amino-Acid Region of CIITA Is an Effective Inhibitor of CBP: Novel Mechanism of Gamma Interferon-Mediated Suppression of Collagen α2(I) and Other Promoters
Xin-Sheng Zhu & Jenny P.-Y. Ting
Pages: 7078-7088
Published online: 27 Mar 2023
AbstractforA 36-Amino-Acid Region of CIITA Is an Effective Inhibitor of CBP: Novel Mechanism of Gamma Interferon-Mediated Suppression of Collagen α2(I) and Other Promoters | Full Text | References | PDF (705.7 KB)
  • 16 Views
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Article
Mitogen-Regulated RSK2-CBP Interaction Controls Their Kinase and Acetylase Activities
Karine Merienne, Solange Pannetier, Annick Harel-Bellan & Paolo Sassone-Corsi
Pages: 7089-7096
Published online: 27 Mar 2023
AbstractforMitogen-Regulated RSK2-CBP Interaction Controls Their Kinase and Acetylase Activities | Full Text | References | PDF (293.9 KB)
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Article
The Modified Human DNA Repair EnzymeO6-Methylguanine-DNA Methyltransferase Is a Negative Regulator of Estrogen Receptor-Mediated Transcription upon Alkylation DNA Damage
Alvin K. C. Teo, Hue Kian Oh, Rahmen B. Ali & Benjamin F. L. Li
Pages: 7105-7114
Published online: 27 Mar 2023
AbstractforThe Modified Human DNA Repair EnzymeO6-Methylguanine-DNA Methyltransferase Is a Negative Regulator of Estrogen Receptor-Mediated Transcription upon Alkylation DNA Damage | Full Text | References | PDF (528.9 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Hematopoietic Protein Tyrosine Phosphatase Suppresses Extracellular Stimulus-Regulated Kinase Activation
Marcela Gronda, Sara Arab, Barbara Iafrate, Haruhiko Suzuki & Brent W. Zanke
Pages: 6851-6858
Published online: 27 Mar 2023
AbstractforHematopoietic Protein Tyrosine Phosphatase Suppresses Extracellular Stimulus-Regulated Kinase Activation | Full Text | References | PDF (194 KB)
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Article
RhoB Is Dispensable for Mouse Development, but It Modifies Susceptibility to Tumor Formation as Well as Cell Adhesion and Growth Factor Signaling in Transformed Cells
Ai-Xue Liu, Neena Rane, Jeh-Ping Liu & George C. Prendergast
Pages: 6906-6912
Published online: 27 Mar 2023
AbstractforRhoB Is Dispensable for Mouse Development, but It Modifies Susceptibility to Tumor Formation as Well as Cell Adhesion and Growth Factor Signaling in Transformed Cells | Full Text | References | PDF (754.7 KB)
  • 36 Views
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Article
Idiopathic Weight Reduction in Mice Deficient in the High-Mobility-Group Transcription Factor Sox8
Elisabeth Sock, Katy Schmidt, Irm Hermanns-Borgmeyer, Michael R. Bösl & Michael Wegner
Pages: 6951-6959
Published online: 27 Mar 2023
AbstractforIdiopathic Weight Reduction in Mice Deficient in the High-Mobility-Group Transcription Factor Sox8 | Full Text | References | PDF (1 MB)
  • 50 Views
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Article
Cse1l Is Essential for Early Embryonic Growth and Development
Tapan K. Bera, Jayati Bera, Ulrich Brinkmann, Lino Tessarollo & Ira Pastan
Pages: 7020-7024
Published online: 27 Mar 2023
AbstractforCse1l Is Essential for Early Embryonic Growth and Development | Full Text | References | PDF (919.2 KB)
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Article
Perinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice
Günter Kostka, Richard Giltay, Wilhelm Bloch, Klaus Addicks, Rupert Timpl, Reinhard Fässler & Mon-Li Chu
Pages: 7025-7034
Published online: 27 Mar 2023
AbstractforPerinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice | Full Text | References | PDF (1.4 MB)
  • 38 Views
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Article
Gene Targeting of Envoplakin, a Cytoskeletal Linker Protein and Precursor of the Epidermal Cornified Envelope
Arto Määttä, Teresa DiColandrea, Karen Groot & Fiona M. Watt
Pages: 7047-7053
Published online: 27 Mar 2023
AbstractforGene Targeting of Envoplakin, a Cytoskeletal Linker Protein and Precursor of the Epidermal Cornified Envelope | Full Text | References | PDF (1.2 MB)
  • 17 Views
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Cell and Organelle Structure and Assembly

Article
Mitochondrial Import Driving Forces: Enhanced Trapping by Matrix Hsp70 Stimulates Translocation and Reduces the Membrane Potential Dependence of Loosely Folded Preproteins
Andreas Geissler, Joachim Rassow, Nikolaus Pfanner & Wolfgang Voos
Pages: 7097-7104
Published online: 27 Mar 2023
AbstractforMitochondrial Import Driving Forces: Enhanced Trapping by Matrix Hsp70 Stimulates Translocation and Reduces the Membrane Potential Dependence of Loosely Folded Preproteins | Full Text | References | PDF (316.7 KB)
  • 11 Views
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Author's Correction

Correction
Mapping of a Serine-Rich Domain Essential for the Transcriptional, Antiapoptotic, and Transforming Activities of the v-Rel Oncoprotein
Page: 7115
Published online: 27 Mar 2023
CitationforMapping of a Serine-Rich Domain Essential for the Transcriptional, Antiapoptotic, and Transforming Activities of the v-Rel Oncoprotein | Full Text | PDF (17.2 KB)
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