Publication Cover
Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 28, 2006 - Issue 3: Multiple Sclerosis
69
Views
56
CrossRef citations to date
0
Altmetric
Articles

Progressive multifocal leukoencephalopathy: lessons from AIDS and natalizumab

&
Pages 299-305 | Published online: 19 Jul 2013

REFERENCES

  • Miller DH, Khan OA, Sheremata WA, et al. A controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348: 15–23
  • O'Connor PW, Goodman A, Willmer-Hulme AJ, et al. Randomized multicenter trial of natalizumab in acute MS relapses: Clinical and MRI effects. Neurology 2004; 62: 2038–2043
  • Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-la for multiple sclerosis. N Engl J Med 2005; 353: 369–374
  • Langer-Gould A, Atlas SW, Green AJ, et al. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med 2000; 5353: 375–381
  • Van Assche G, Van Ranst M, Sciot R, et al. Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med 2005; 353: 362–368
  • Berger JR, Koralnik IJ. Progressive multifocal leukoencephalopathy and natal izumab—unforeseen consequences. N Engl I Med 2005; 353: 414–416
  • Astrom KE, Mancall EL, Richardson EP, Jr. Progressive multifocal leuko-encephalopathy; a hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin's disease. Brain 1958; 81: 93–111
  • Berger JR, Pall L, Lanska D, et al. Progressive multifocal leukoencephalopathy in patients with HIV infection. I Neurovirol 1998; 4: 59–68
  • Brooks BR, Walker DL. Progressive multifocal leukoencephalo-pathy. Neurol Clin 1984; 2: 299–313
  • Whiteman ML, Post MJ, Berger JR, et al. Progressive multifocal leukoencephalopathy in 47 HIV-seropositive patients: Neuroimaging with clinical and pathologic correlation. Radiology 1993; 187: 233–240
  • Safdar A, Rubocki RJ, Horvath JA, et al. Fatal immune restoration disease in human immunodeficiency virus type 1-infected patients with progressive multifocal leukoencephalopathy: Impact of antiretroviral therapy-associated immune reconstitution. Clin Infect Dis 2002; 35: 1250–1257
  • Vendrely A, Bienvenu B, Gasnault J, et al. Fulminant inflammatory leukoencephalopathy associated with HAART-induced immune restoration in AIDS-related progressive multifocal leukoencepha-lopathy. Acta Neuropathol (Berl) 2005; 109: 449–455
  • Bernick C, Gregorios JB. Progressive multifocal leukoencephalo-pathy in a patient with acquired immune deficiency syndrome. Arch Neurol 1984; 41: 780–782
  • Miller JR, Barrett RE, Britton CB, et al. Progressive multifocal leukoencephalopathy in a male homosexual with T-cell immune deficiency. N Engl J Med 1982; 307: 1436–1438
  • Snider WD, Simpson DM, Nielsen S, Gold JW, Hetroka CE, Posner JB. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 1983; 19: 403–18
  • Major EO, Amemiya K, Tornatore CS, et al. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Microbiol Rev 1992; 5: 49–73
  • Holman RC, Janssen RS, Buehler JW, et al. Epidemiology of progressive multifocal leukoencephalopathy in the United States: Analysis of national mortality and AIDS surveillance data. Neurology 1991; 41:1733–1736
  • ZuRhein GM, Chow SM. Particles resembling papovavirions in human cerebral demyelinating disease. Science 1965; 148: 1477–1479
  • Padgett BL, Walker DL, ZuRhein GM, et al. Cultivation of papova-like virus from human brain with progressive multifocal leucoen-cephalopathy. Lancet 1971; 1:1257–1260
  • Khalili K, Del Valle L, Otte J, et al. Human neurotropic polyomavirus, JCV, and its role in carcinogenesis. Oncogene 2003; 22: 5181-5191
  • Walker DL, Padgett BL. The epidemiology of human polyoma-viruses. In: Sever JL, Madden D, eds. Polyoma viruses and human neurological disease, New York: Alan R. Liss, 1983: pp. 99–106
  • Brown P, Tsai T, Gajdusek DC. Seroepidemiology of human papovaviruses. Discovery of virgin populations and some unusual patterns of antibody prevalence among remote peoples of the world. Am] Epidemiol 1975; 102: 331–340
  • Caldarelli-Stefano R, Vago L, Omodeo-Zorini E, et al. Detection and typing of JC virus in autopsy brains and extraneural organs of AIDS patients and non-immunocompromised individuals. I Neurovirol 1999; 5: 125–133
  • Monaco MC, Atwood WJ, Gravell M, et al. JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: Implications for viral latency. J Virol 1996; 70: 7004–7012
  • Sabath BE, Major EO. Traffic of JC virus from sites of initial infection to the brain: The path to progressive multifocal leukoencephalopathy. J Infect Dis 2002; 186 (Suppl. 2): S180—S186
  • Monaco MC, Jensen PN, Hou J, et al. Detection of JC virus DNA in human tonsil tissue: Evidence for site of initial viral infection. J Virol 1998; 72: 9918–9923
  • Tornatore C, Berger JR, Houff SA, et al. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Ann Neurol 1992; 31: 454–462
  • Andreoletti L, Lescieux A, Lambert V, et al. Semiquantitative detection of JCV-DNA in peripheral blood leukocytes from HIV-1-infected patients with or without progressive multifocal leukoen-cephalopathy. J Med Virol 2002; 66: 1–7
  • Berger JR, Miller C, Mootoor Y, etal. Are saliva and oropharyngeal secretions a source of JCV infection? Present at the third International Polyomavirus Conference, 2005, Providence, RI, USA
  • Dubois V, Lafon ME, Ragnaud JM, et al. Detection of JC virus DNA in the peripheral blood leukocytes of HIV-infected patients. AIDS 1996; 10: 353–358
  • Koralnik IJ, Boden D, Mai VX, et al. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology 1999; 52: 253–260
  • Weber T, Weber F, Petry H, et al. Immune response in progressive multifocal leukoencephalopathy: An overview. J Neurovirol 2001; 7: 311–317
  • Berger JR. Progressive multifocal leukoencephalopathy in acquired immunodeficiency syndrome: Explaining the high incidence and disproportionate frequency of the illness relative to other immunosuppressive conditions. J Neurovirol 2003; 9 (Suppl 1.): S38—S41
  • D'Souza M, Fauci A. Immunopathogenesis. In: Merigan TC, Bartlett JG, Bolognesi D, eds. Textbook of AIDS Medicine, 2nd edn, Baltimore, MA, USA: Williams & Wilkins, 1999: pp. 59-86
  • Houff SA, Major E0, Katz DA, et al. Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. N Engl J Med 1988; 318: 301–315
  • Major E0, Amemiya K, Elder G, et al. Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. J Neurosci Res 1990; 27: 461–471
  • Koralnik IJ, Schmitz JE, Lifton MA, et al. Detection of JC virus DNA in peripheral blood cell subpopulations of HIV-1-infected indivi-duals. J Neurovirol 1999; 5: 430–435
  • Persidsky Y, Zheng J, Miller D, et al. Mononuclear phagocytes mediate blood—brain barrier compromise and neuronal injury during HIV-1-associated dementia. J Leukoc Biol 2000; 68: 413–422
  • Petito CK, Cash KS. Blood—brain barrier abnormalities in the acquired immunodeficiency syndrome: Immunohistochemical localization of serum proteins in postmortem brain. Ann Neurol 1992; 32: 658–666
  • Berger JR, Nath A, Greenberg RN, et al. Cerebrovascular changes in the basal ganglia with HIV dementia. Neurology 2000; 54: 921-926
  • Nottet HS, Persidsky Y, Sasseville VG, et al. Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. J Immunol 1996; 156: 1284–1295
  • Berger JR, Chauhan A, Galey D, et al. Epidemiological evidence and molecular basis of interactions between HIV and JC virus. J Neurovirol 2001; 7: 329–338
  • Tada H, Rappaport J, Lashgari M, et al. Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells. Proc Natl Acad Sci USA 1990; 87: 3479–3483
  • Kim SY, Choi EC, Woo Jo Y, et al. Transcriptional activation of JC virus early promoter by phorbol ester and interleukin-1beta: Critical role of nuclear factor-1. Virology 2004; 327: 60–69
  • Enam S, Sweet TM, Amini S, et al. Evidence for involvement of transforming growth factor beta1 signaling pathway in activation of JC virus in human immunodeficiency virus 1-associated progressive multifocal leukoencephalopathy. Arch Pathol Lab Med 2004; 128: 282–291
  • Rudick RA, Sandrock A. Natalizumab: Alpha4-integrin antagonist selective adhesion molecule inhibitors for MS. Expert Rev Neurother 2004; 4: 571–580
  • Tubridy N, Behan PO, Capildeo R, et al. The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group. Neurology 1999; 53: 466–472
  • Lu TT, Cyster JG. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 2002; 297: 409–412
  • von Andrian UH, Engelhardt B. Alpha4 integrins as therapeutic targets in autoimmune disease. N Engl J Med 2003; 348: 68–72
  • Major EO. JC virus in the CSF and plasma of natalizumab treated patients. In: Paper presented at ECTRIMS, Thessaloniki, Greece:, 2005
  • Koralnik IJ. Overview of the cellular immunity against JC virus in progressive multifocal I eu koencephal opathy. J Neurovirol 2002; 8 (Suppl. 2): S59—S65
  • Koralnik IJ, Du Pasquier RA, Letvin NL. JC virus-specific cytotoxic T lymphocytes in individuals with progressive multifocal leukoen-cephalopathy. J Virol 2001; 75: 3483–3487
  • Ferrante P, Omodeo-Zorini E, Caldarelli-Stefano R, et al. Detection of JC virus DNA in cerebrospinal fluid from multiple sclerosis patients. Mult Scler 1998; 4: 49–54
  • Olmos Y, Alvarez-Lafuente R, Garcia-Montojo M, et al. JC virus and multiple sclerosis: A study in cerebrospinal fluid samples of multiple sclerosis patients at the first demyelinating event. Mult Scler 2005; 11 (Suppl. 1): S133—S134
  • Bogdanovic G, Priftakis P, Hammarin AL, et al. Detection of JC virus in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy but not in CSF samples from patients with herpes simplex encephalitis, enter-oviral meningitis, or multiple sclerosis. J Clin Microbiol 1998; 36: 1137–1138
  • Olsson T, lacobaeus E, Brundin L. JC viral DNA in a cohort of relapsing-remitting multiple sclerosis patients. Mult Scler 2005; 11 (Suppl. 1): S178
  • Sheridan C. Third Tysabri adverse case hits drug class. Nat Rev Drug Discov 2005; 4: 357–358

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.