Nimesulide – a multifactorial approach to inflammation and pain: scientific and clinical consensus

References

• Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005
   Google Scholar
• European Medicines Evaluation Agency, Committee for Proprietary Medicinal Products. Nimesulide containing medicinal products. CPMP/1724/04. Available from http://www.emea.eu.int/pdfs/human/referral/nimesulide/172404en.pdf [Last accessed Jan 2006]
   Google Scholar
• Rainsford KD. The discovery, development and novel actions of nimesulide. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.1–61
   Google Scholar
• Swingle KF, Bell RL, Moore GGI. Anti-inflammatory activity of antioxidants. In: Anti-inflammatory and anti-rheumatic drugs. Volume III: anti-rheumatic drugs, experimental agents, and clinical aspects of drug use. Boca Raton (Fl): CRC Press, 1985. pp.105–26
   Google Scholar
• Bernareggi A. Clinical pharmacokinetics of nimesulide. Clin Pharmacokinet 1998;35:247–74
   PubMed Web of Science ®Google Scholar
• Bernareggi A, Rainsford KD. Pharmacokinetics of nimesulide. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.63–120,
   Google Scholar
• Maroni A, Gazzaniga A, Rainsford KD. Pharmacokinetics of nimesulide. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.121–32
   Google Scholar
• Bennett A. Nimesulide: a well-established cyclo-oxygenase-2 inhibitor with many other pharmacological properties relevant to inflammatory disease. In: Vane JR, Botting RM, editors. Therapeutic roles of selective COX-2 inhibitors. London: William Harvey Press, 2001. pp.524–40
   Google Scholar
• Bennett A, Villa G. Nimesulide: an NSAID that preferentially inhibits COX-2, and has various unique pharmacological activities. Exp Opin Pharmacother 2000;1:277–86
   PubMedGoogle Scholar
• Warner TD, Giuliano F, Vojnovic I, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A 1999;96:7563–8. Erratum p.9666
   Google Scholar
• Rainsford KD, Bevilacqua M, Dallegri, et al. Pharmacological properties of nimesulide. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.133–244
   Google Scholar
• Bianchi M, Ehrlich GE, Facchinetti F, et al. Clinical applications of nimesulide in pain, arthritic conditions and fever. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.245–313
   Google Scholar
• Bianchi M, Broggini M. Anti-hyperalgesic effect of nimesulide: studies in rats and humans. Int J Clin Pract 2002;128:11–9
   Google Scholar
• Sandrini G, Proietti Cecchini A, Alfonsi E, et al. Effectiveness of nimesulide in pain. A neurophysiological study in humans. Drugs Today 2001;37(B):21–9
   Google Scholar
• Jenoure P, Gorschewsky O, Ryf C, et al. Randomised double-blind study of nimesulide versus diclofenac in adults with acute sport injuries. J Clin Res 1998;1:343–56
   Google Scholar
• Wober W. Comparative efficacy and safety of nimesulide and diclofenac in patients with acute shoulder, and a meta-analysis of controlled studies with nimesulide. Rheumatology (Oxford) 1999;38(Suppl 1):33–8
   PubMedGoogle Scholar
• Pohjolainen T, Jekunen A, Lotta A, et al. Treatment of acute low back pain (LBP) with the COX-2 selective NSAR nimesulide: results of a randomised, double-blind, comparative trial vs. ibuprofen. Spine 2000;25:1579–85
   PubMed Web of Science ®Google Scholar
• Ferrari Parabita G, Zanetti U, Scalvini F, et al. A controlled clinical study of the efficacy and tolerability of nimesulide vs. naproxen in maxillo-facial surgery. Drugs 1993;46(Suppl 1):171–3
   Google Scholar
• American College of Rheumatology. Subcommittee on osteo-arthritis guidelines: recommendations for the medical management of osteoarthritis of the hip and knee. Arthritis Rheum 2000;43:1905–15
   PubMed Web of Science ®Google Scholar
• Barracchini A, Franceschini N, Amicosante G, et al. Can nonsteroidal anti-inflammatory drugs act as metalloproteinase modulators? An in-vitro study of inhibition of collagenase activity. J Pharm Pharmacol 1998;50:1417–23
   PubMed Web of Science ®Google Scholar
• Bevilacqua M, Devogelaer J-P, Righini V, et al. Effect of nimesulide on the serum levels of hyaluronan and stromelysin-1 in patients with osteoarthritis: a pilot study. Int J Clin Pract 2004;144(Suppl):13–9
   Google Scholar
• Huskisson EC, Macciocchi A, Rahlfs VW, et al. Nimesulide versus diclofenac in the treatment of osteoarthritis of the hip or knee: an active controlled equivalent study. Curr Ther Res 1999;60:253–65
   Web of Science ®Google Scholar
• Kriegel W, Korff KJ, Ehrlich JC, et al. Double-blind study comparing the long-term efficacy of the COX-2 inhibitor nimesulide and naproxen in patients with osteoarthritis. Int J Clin Pract 2001;55:510–4
   PubMed Web of Science ®Google Scholar
• Bianchi M, Broggini M. A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee. Drugs 2003;63(Suppl 1):37–46
   PubMed Web of Science ®Google Scholar
• Pulkkinen MO. Is there a rationale for the use of nimesulide in the treatment of dysmenorrhea? Drugs Today 2001;37(Suppl B):31–8
   Google Scholar
• Facchinetti F, Piccinini F, Sgarbi L, et al. Nimesulide in the treatment of primary dysmenorrhea: a double-blind study versus diclofenac. Drugs Today 2001;37(Suppl B):39–45
   Google Scholar
• Bjarnason I, Bissoli F, Conforti A, et al. Adverse reactions and their mechanisms from nimesulide. In: Rainsford KD, editor. Nimesulide. Actions and uses. Basel: Birkhäuser, 2005. pp.315–415
   Google Scholar
• Shah AA, Thjodleifsson B, Murray FE, et al. Selective inhibition of COX-2 in humans is associated with less gastro-intestinal injury: a comparison of nimesulide and naproxen. Gut 2001;48:339–46
   PubMed Web of Science ®Google Scholar
• Conforti A, Leone R, Moretti U, et al. Adverse drug reactions related to the use of NSAIDs with a focus on nimesulide. Drug Saf 2001;24:1081–90
   PubMed Web of Science ®Google Scholar
• Laporte JR, Ibanez I, Vidal X, et al. Upper gastro-intestinal bleeding associated with the use of NSAIDs: newer vs. older agents. Drug Saf 2004;27:411–20
   PubMed Web of Science ®Google Scholar
• Boelsterli UA. Nimesulide and hepatic adverse effects: roles of reactive metabolites and host factors. Int J Clin Pract Suppl 2002;128:30–6
   PubMedGoogle Scholar
• Traversa G, Bianchi C, Da Cas R, et al. Cohort study of hepatotoxicity associated with nimesulide and other nonsteroidal anti-inflammatory drugs. BMJ 2003;327:18–22
   PubMed Web of Science ®Google Scholar