Improving the design of maintenance studies for bipolar disorder

References

• Hirschfeld RMA, Bowden CL, Gitlin MJ, et al. American Psychiatric Association practice guideline for the treatment of patients with bipolar disorder (Revision). American J Psychiatry 2002;159(Suppl. 4):1-50
   Web of Science ®Google Scholar
• Goodwin FK, Jamison KR. Manic–Depressive Illness: Bipolar Disorders and Recurrent Depression, 2nd Edn. NY: Oxford University Press, 2007
   Google Scholar
• Perlis RH, Ostacher MJ, Patel JK, et al. Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP -BD). Am J Psychiatry 2006;163:217-24
   PubMed Web of Science ®Google Scholar
• Gitlin MJ, Swendsen J, Heller TL, Hammen C. Relapse and impairment in bipolar disorder. Am J Psychiatry 1995;152:1635-40
   PubMed Web of Science ®Google Scholar
• Winokur G, Coryell W, Akiskal HS, et al. Manic–depressive (bipolar) disorder: the course in light of a prospective ten-year follow-up of 131 patients. Acta Psychiatr Scand 1994; 89:102-10
   PubMed Web of Science ®Google Scholar
• Levine J, Chengappa KNR, Brar JS, et al. Psychotropic drug prescription patterns among patients with bipolar I disorder. Bipolar Disord 2000;2:120-30
   PubMed Web of Science ®Google Scholar
• Nolen WA, Luckenbaugh DA, Altshuler LL, et al. Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley foundation bipolar network. Am J Psychiatry 2004;161:1447-54
   PubMed Web of Science ®Google Scholar
• Judd LL, Akiskal HS, Schettler PJ, et al. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry 2003;60:261-9
   PubMed Web of Science ®Google Scholar
• Judd LL, Akiskal HS, Schettler PJ, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59:530-7
   PubMed Web of Science ®Google Scholar
• Prien RF, Caffey EM Jr, Klett CJ. Prophylactic efficacy of lithium carbonate in manic–depressive illness. Report of the Veterans Administration and National Institute of Mental Health collaborative study group. Arch Gen Psychiatry 1973;28:337-41
   PubMed Web of Science ®Google Scholar
• Bowden CL, Calabrese JR, McElroy SL, et al. A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group. Arch Gen Psychiatry 2000;57:481-9
   PubMed Web of Science ®Google Scholar
• Tohen M, Calabrese JR, Sachs GS, et al. Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine. Am J Psychiatry 2006;163:247-56
   PubMed Web of Science ®Google Scholar
• Bowden CL, Calabrese JR, Sachs G, et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003;60:392-400
   PubMed Web of Science ®Google Scholar
• Calabrese JR, Bowden CL, Sachs G, et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder. J Clin Psychiatry 2003;64:1013-24
   PubMed Web of Science ®Google Scholar
• Keck PE Jr, Calabrese JR, McQuade RD, et al. A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorder. J Clin Psychiatry 2006;67:626-37
   PubMed Web of Science ®Google Scholar
• Keck PE Jr, Calabrese JR, McIntyre RS, et al. Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo. J Clin Psychiatry 2007;68:1480-91
   PubMed Web of Science ®Google Scholar
• Tohen M, Chengappa KN, Suppes T, et al. Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone. Br J Psychiatry 2004;184:337-45
   PubMed Web of Science ®Google Scholar
• Vieta E, Suppes T, Eggens I, et al. Efficacy and safety of quetiapine in combination with lithium/divalproex as maintenance treatment for bipolar I disorder (international trial 126). J Affect Disord 2008;109:251 -63
   PubMed Web of Science ®Google Scholar
• Suppes T, Vieta E, Liu S, et al. Maintenance treatment for patients with bipolar I disorder: results from a North American study of quetiapine in combination with lithium or divalproex (Trial 127). Am J Psychiatry 2009:166:476-83
   PubMed Web of Science ®Google Scholar
• Bowden CL, Vieta E, Ice KS, et al. Ziprasidone plus a mood stabilizer in subjects with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind trial. J Clin Psychiatry 2010:71:130-7
   PubMed Web of Science ®Google Scholar
• Mcfadden W, Alphs L, Haskins TJ, et al. A randomized, double-blind, placebo-controlled study of maintenance treatment with adjunctive risperidone long-acting therapy in patients with bipolar I disorder who relapse frequently. Bipolar Disorders 2009;11:827-39
   PubMed Web of Science ®Google Scholar
• Data on File, File Number ABIL 046. Bristol-Myers Squibb and Otsuka America Pharmaceutical, Inc
   Google Scholar
• Faedda GL, Tondo L, Baldessarini RJ, et al. Outcome after rapid vs gradual discontinuation of lithium treatment in bipolar disorders. Arch Gen Psychiatry 1993;50:448-55
   PubMed Web of Science ®Google Scholar
• Frye MA, Ketter TA, Leverich GS, et al. The increasing use of polypharmacotherapy for refractory mood disorders: 22 years of study. J Clin Psychiatry 2000;61:9-15
   PubMed Web of Science ®Google Scholar
• Goldberg JF, Brooks JO 3rd, Kurita K, et al. Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP -BD. J Clin Psychiatr 2009;70:155-62
   PubMed Web of Science ®Google Scholar
• Tohen M, Hennen J, Zarate CM, et al. Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features. Am J Psychiatry 2000;157:220-8
   PubMed Web of Science ®Google Scholar
• Geddes JR, Rendell JM, Goodwin GM, et al. BALANCE: a large simple trial of maintenance for bipolar disorder. World Psychiatry 2002;1:48-51
   PubMedGoogle Scholar
• The BALANCE investigators and collaborators, Geddes JR, et al. Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. Lancet 2010;375:385-95
   Google Scholar
• Geddes GR. BALANCE: PL Initial Results and Methodological Aspects of Trials of Maintenance Treatment. Poster presented at the 8th International Conference on Bipolar Disorder, Pittsburgh, PA, June 25–27, 2009
   Google Scholar