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Research Article

Peripheral mechanism of action of fenfluramine

Pages 101-106 | Accepted 19 Oct 1978, Published online: 21 Aug 2008

References

  • Bajaj J. S., Vallance-Owen J. Fenfluramine and glucose uptake by muscle. Harm. Metab. Res. 1974; 6: 851. Bajaj J. S., Vallance-Owen J. Fenfluramine and glucose uptake by muscle. Harm. Metab. Res. 1974; 6: 85
  • Bliss B. P., Kirk C. J. C., Newall R. G. The effect of fenfluramine on glucose tolerance, insulin, lipid and lipoprotein levels in patients with arterial disease. Postgrad. Med. J. 1972; 48: 4092. Bliss B. P., Kirk C. J. C., Newall R. G. The effect of fenfluramine on glucose tolerance, insulin, lipid and lipoprotein levels in patients with arterial disease. Postgrad. Med. J. 1972; 48: 409
  • Brindley D. N. Some aspects of the physiological and pharmacological control of the synthesis of triacylglycerols and phospholipids. Int. J. Obesity 1978; 2: 73. Brindley D. N. Some aspects of the physiological and pharmacological control of the synthesis of triacylglycerols and phospholipids. Int. J. Obesity 1978; 2: 7
  • Brindley D. N., Bowley M. Effects of fenfluramine and related compounds on the synthesis of glycerolipids by rat liver. Postgrad. Med. J. 1975; 51: 91, Suppl. 14. Brindley D. N., Bowley M. Effects of fenfluramine and related compounds on the synthesis of glycerolipids by rat liver. Postgrad. Med. J. 1975; 51: 91, Suppl. 1
  • Butterfield W. J. H., Whichelow M. J. Fenfluramine and muscle glucose uptake in man. Lancet 1968; 1: 1095. Butterfield W. J. H., Whichelow M. J. Fenfluramine and muscle glucose uptake in man. Lancet 1968; 1: 109
  • Chremos A. N., Dannenburg W. N., Noble R. E. Plasma lipid and weight changes of obese subjects treated with fenfluramine. Diabetes 1971; 20: 351, Suppl. 16. Chremos A. N., Dannenburg W. N., Noble R. E. Plasma lipid and weight changes of obese subjects treated with fenfluramine. Diabetes 1971; 20: 351, Suppl. 1
  • Dannenburg W. N., Kardian B. C. Metabolic effects of fenfluramine and methamphetamine on free fatty acid release and glucose utilization in epididymal fat cells of the rat. Amphetamines and Related Compounds, E. Costa, S. Garattini. Raven Press, New York 1970; 597–6107. Dannenburg W. N., Kardian B. C. Metabolic effects of fenfluramine and methamphetamine on free fatty acid release and glucose utilization in epididymal fat cells of the rat. Amphetamines and Related Compounds, E. Costa, S. Garattini. Raven Press, New York 1970; 597–610
  • Dannenburg W.N., Kardian B. C., Norrell L. Y. Fenfluramine and triglyceride synthesis by microsomes of the intestinal mucosa in the rat. Arch. Int. Pharmacodyn. Thér. 1973; 201: 1158. Dannenburg W.N., Kardian B. C., Norrell L. Y. Fenfluramine and triglyceride synthesis by microsomes of the intestinal mucosa in the rat. Arch. Int. Pharmacodyn. Thér. 1973; 201: 115
  • Durnin J., Womersley J. The metabolic effects, and the composition of the tissue lost, in weight reduction by obese patients on treatment with fenfluramine. Br. J. Pharmacol. 1973; 49: 1159. Durnin J., Womersley J. The metabolic effects, and the composition of the tissue lost, in weight reduction by obese patients on treatment with fenfluramine. Br. J. Pharmacol. 1973; 49: 115
  • Dykes J. R. W. The effect of a low-calorie diet with and without fenfluramine on the glucose tolerance and insulin secretion of obese maturity-onset diabetics. Postgrad. Med. J. 1973; 49: 31810. Dykes J. R. W. The effect of a low-calorie diet with and without fenfluramine on the glucose tolerance and insulin secretion of obese maturity-onset diabetics. Postgrad. Med. J. 1973; 49: 318
  • Dykes J. R. W. The effect of a low-calorie diet with and without fenfluramine and fenfluramine alone on the glucose tolerance and insulin secretion of over-weight non-diabetics. Postgrad. Med. J. 1973; 49: 31411. Dykes J. R. W. The effect of a low-calorie diet with and without fenfluramine and fenfluramine alone on the glucose tolerance and insulin secretion of over-weight non-diabetics. Postgrad. Med. J. 1973; 49: 314
  • Fernstrom J. D., Wurtman R. J. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science 1972; 178: 41412. Fernstrom J. D., Wurtman R. J. Brain serotonin content: physiological regulation by plasma neutral amino acids. Science 1972; 178: 414
  • Frayn K. N., Hedges A., Kirby M. J. Stimulation by fenfluramine of glucose uptake into skeletal muscle in vitro. Horm. Metab. Res. 1974; 6: 8613. Frayn K. N., Hedges A., Kirby M. J. Stimulation by fenfluramine of glucose uptake into skeletal muscle in vitro. Horm. Metab. Res. 1974; 6: 86
  • Harrison L. C., King-Roach A., Martin F. I. R., Melick R. A. The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of L-14C-glucose by human adipose tissue. Postgrad. Med. J. 1975; 51: 110, Suppl. 114. Harrison L. C., King-Roach A., Martin F. I. R., Melick R. A. The effect of fenfluramine on insulin binding and on basal and insulin-stimulated oxidation of L-14C-glucose by human adipose tissue. Postgrad. Med. J. 1975; 51: 110, Suppl. 1
  • Innes J. A., Watson M. L., Ford M. J., Munro J. F., Stoddart M. E., Campbell D. B. Plasma fenfluramine levels, weight loss and side-effects. Br. Med. J. 1977; 2: 132215. Innes J. A., Watson M. L., Ford M. J., Munro J. F., Stoddart M. E., Campbell D. B. Plasma fenfluramine levels, weight loss and side-effects. Br. Med. J. 1977; 2: 1322
  • Jørgensen K. D. Actions of fenfluramine on glucose uptake in vitro and in vivo. Acta Pharmacol. Toxicol. (Kbh.) 1977; 40: 40116. Jørgensen K. D. Actions of fenfluramine on glucose uptake in vitro and in vivo. Acta Pharmacol. Toxicol. (Kbh.) 1977; 40: 401
  • Kaye J. P., Tomlin S., Galton D. J. The effect of fenfluramine and its derivatives on triglyceride secretion by the liver of the rabbit. Postgrad. Med. J. 1975; 51: 95, Suppl. 117. Kaye J. P., Tomlin S., Galton D. J. The effect of fenfluramine and its derivatives on triglyceride secretion by the liver of the rabbit. Postgrad. Med. J. 1975; 51: 95, Suppl. 1
  • Kirby M. J. Dose-related effect of fenfluramine and norfenfluramine on glucose uptake into human isolated skeletal muscle. Br. J. Clin. Pharmacol. 1974; 1: 51118. Kirby M. J. Dose-related effect of fenfluramine and norfenfluramine on glucose uptake into human isolated skeletal muscle. Br. J. Clin. Pharmacol. 1974; 1: 511
  • Kirby M. J., Turner P. The effect of amphetamine on glucose uptake into the rat isolated hemidiaphragm. J. Pharm. Pharmacol. 1974; 26: 46319. Kirby M. J., Turner P. The effect of amphetamine on glucose uptake into the rat isolated hemidiaphragm. J. Pharm. Pharmacol. 1974; 26: 463
  • Kirby M. J., Turner P. Fenfluramine and norfenfluramine on glucose uptake into skeletal muscle. Postgrad. Med. J. 1975; 51: 73, Suppl. 120. Kirby M. J., Turner P. Fenfluramine and norfenfluramine on glucose uptake into skeletal muscle. Postgrad. Med. J. 1975; 51: 73, Suppl. 1
  • Kirby M. J., Turner P. Increase in human skeletal muscle lactate produced by fenfluramine. Nature 1976; 262: 61721. Kirby M. J., Turner P. Increase in human skeletal muscle lactate produced by fenfluramine. Nature 1976; 262: 617
  • Kirby M. J., Turner P. The effect of methysergide and other receptor antagonists on fenfiuramine-induced glucose uptake into the isolated rat hemidiaphragm. Arch. Int. Pharmacodyn. Thér. 1977; 225: 2522. Kirby M. J., Turner P. The effect of methysergide and other receptor antagonists on fenfiuramine-induced glucose uptake into the isolated rat hemidiaphragm. Arch. Int. Pharmacodyn. Thér. 1977; 225: 25
  • Mace P. B., Malcolm K. P., Outar K. P., Pawan G. L. S. Comparative effects of four anti-obesity agents on blood plasma lipids in man. Proc. Nutr. Soc 1972; 31: 14A23. Mace P. B., Malcolm K. P., Outar K. P., Pawan G. L. S. Comparative effects of four anti-obesity agents on blood plasma lipids in man. Proc. Nutr. Soc 1972; 31: 14A
  • Macrae S. M. Peripheral and metabolic effects of fenfluramine, 780 SE, norfenfluramine and hydroxyethylnorfenfluramine - a review. Postgrad. Med. J. 1975; 51: 13, Suppl. 124. Macrae S. M. Peripheral and metabolic effects of fenfluramine, 780 SE, norfenfluramine and hydroxyethylnorfenfluramine - a review. Postgrad. Med. J. 1975; 51: 13, Suppl. 1
  • Marsh J. B., Bizzi A. Effects of amphetamine and fenfluramine on the net release of triglycerides of very low density lipoproteins by slices of rat liver. Biochem. Pharmacol. 1972; 21: 114325. Marsh J. B., Bizzi A. Effects of amphetamine and fenfluramine on the net release of triglycerides of very low density lipoproteins by slices of rat liver. Biochem. Pharmacol. 1972; 21: 1143
  • Pawan G. L. S. Effect of fenfluramine on blood lipids in man. Lancet 1969; 1: 49826. Pawan G. L. S. Effect of fenfluramine on blood lipids in man. Lancet 1969; 1: 498
  • Turtle J. R., Burgess J. A. Hypoglycaemic action of fenfluramine in diabetes mellitus. Diabetes 1973; 22: 85827. Turtle J. R., Burgess J. A. Hypoglycaemic action of fenfluramine in diabetes mellitus. Diabetes 1973; 22: 858
  • Whichelow M. J., Butterfield W. J. H. Effects of fenfluramine on peripheral glucose metabolism in man. Amphetamines and Related Compounds, E. Costa, S. Garattini. Raven Press, New York 1970; 611–61828. Whichelow M. J., Butterfield W. J. H. Effects of fenfluramine on peripheral glucose metabolism in man. Amphetamines and Related Compounds, E. Costa, S. Garattini. Raven Press, New York 1970; 611–618
  • Wilson J. P. D., Galton D. J. The effect of drugs on lipogenesis from glucose and palmitate in human adipose tissue. Horm. Metab. Res. 1971; 3: 26229. Wilson J. P. D., Galton D. J. The effect of drugs on lipogenesis from glucose and palmitate in human adipose tissue. Horm. Metab. Res. 1971; 3: 262
  • Wurtman R. J. Effects of nutrients and circulating precursors on the synthesis of brain neurotransmitters. Central Mechanisms of Anorectic Drugs, S. Garattini, R. Samanin. Raven Press, New York 1978; 267–29430. Wurtman R. J. Effects of nutrients and circulating precursors on the synthesis of brain neurotransmitters. Central Mechanisms of Anorectic Drugs, S. Garattini, R. Samanin. Raven Press, New York 1978; 267–294

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