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Journal of the International Society of Sports Nutrition Volume 11, 2014 - Issue 1

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Research Article

Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial

Franchek Drobnic1 Olympic Training Centre (CAR)BarcelonaSpainCorrespondence[email protected]

Joan Riera1 Olympic Training Centre (CAR)BarcelonaSpain

Giovanni Appendino2 Università degli Studi del Piemonte OrientaleNovaraItaly

Stefano Togni3 Indena s.p.a.MilanoItaly

Federico Franceschi3 Indena s.p.a.MilanoItaly

Xavier Valle4 University of BarcelonaSchool of Sports Medicine, Medical ServicesFCBarcelonaSpain

Antoni Pons5 Department Biologia Fonamental i de la SalutUniversity of Illes BalearsMallorcaSpain

Josep Tur5 Department Biologia Fonamental i de la SalutUniversity of Illes BalearsMallorcaSpain

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Article: 31 | Published online: 01 Apr 2022

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https://doi.org/10.1186/1550-2783-11-31
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ArmstrongRBInitial events in exercise-induced muscular injuryMed Sci Sports Exerc199022 429 435 1:STN:280:DyaK3czosVentA%3D%3D https://doi.org/10.1249/00005768-199002000-00007 2205778
PubMed Web of Science ®Google Scholar
FrancisKTHooblerTEffects of aspirin on delayed muscle sorenessJ sports Med Physical Fitness198727 333 337 1:STN:280:DyaL1c7itVensQ%3D%3D
PubMed Web of Science ®Google Scholar
BeckTWHoushTJJohnsonGOSchmidtRJHoushDJCoburnJWMalekMHMielkeMEffects of a protease supplement on eccentric exercise-induced markers of delayed-onset muscle soreness and muscle damageJ Strength Cond Res/ National Strength & Conditioning Association200721 661 667
PubMed Web of Science ®Google Scholar
CockburnEHayesPRFrenchDNStevensonESt Clair Gibson A: Acute milk-based protein-CHO supplementation attenuates exercise-induced muscle damage. Applied physiology, nutrition, and metabolism = Physiol Appl Nutr Metab200833 775 783 1:CAS:528:DC%2BD1cXptFSqtbg%3D https://doi.org/10.1139/H08-057
PubMed Web of Science ®Google Scholar
DudleyGAMuscle pain prophylaxisInflammopharmacology19997 249 253 1:STN:280:DC%2BD2svitVWmtA%3D%3D https://doi.org/10.1007/s10787-999-0007-y 17638095
PubMedGoogle Scholar
GulickDTKimuraIFSitlerMPaoloneAKellyJDVarious treatment techniques on signs and symptoms of delayed onset muscle sorenessJ Athl Train199631 145 152 1318445 1:STN:280:DC%2BC3cngsF2jsg%3D%3D 16558388
PubMedGoogle Scholar
ZainuddinZNewtonMSaccoPNosakaKEffects of massage on delayed-onset muscle soreness, swelling, and recovery of muscle functionJ Athl Train200540 174 180 1250256 16284637
PubMed Web of Science ®Google Scholar
ProskeUMorganDLMuscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applicationsJ Physiol2001537 333 345 2278966 1:CAS:528:DC%2BD3MXptlKgsLg%3D https://doi.org/10.1111/j.1469-7793.2001.00333.x 11731568
PubMed Web of Science ®Google Scholar
AoiWNaitoYTakanamiYKawaiYSakumaKIchikawaHYoshidaNYoshikawaTOxidative stress and delayed-onset muscle damage after exerciseFree Radic Biol Med200437 480 487 1:CAS:528:DC%2BD2cXlsl2msrs%3D https://doi.org/10.1016/j.freeradbiomed.2004.05.008 15256219
PubMed Web of Science ®Google Scholar
PizzaFXPetersonJMBaasJHKohTJNeutrophils contribute to muscle injury and impair its resolution after lengthening contractions in miceJ Physiol2005562 899 913 1665528 1:CAS:528:DC%2BD2MXht1Cgs7o%3D https://doi.org/10.1113/jphysiol.2004.073965 15550464
PubMed Web of Science ®Google Scholar
TaulerPAguiloACasesNSuredaAGimenezFVillaGCordovaABiescasAPAcute phase immune response to exercise coexists with decreased neutrophil antioxidant enzyme defencesFree Radic Res200236 1101 1107 1:CAS:528:DC%2BD38Xos1agsbw%3D https://doi.org/10.1080/1071576021000028334 12516882
PubMed Web of Science ®Google Scholar
FerrerMDTaulerPSuredaAPujolPDrobnicFTurJAPonsAA soccer match’s ability to enhance lymphocyte capability to produce ROS and induce oxidative damageInt J Sport Nutr Exerc Metab200919 243 258 1:CAS:528:DC%2BD1MXosVaqs70%3D 19574612
PubMed Web of Science ®Google Scholar
JuliusDTRP channels and painAnnu Rev Cell Dev Biol201329 355 384 1:CAS:528:DC%2BC3sXhvFSqurfK https://doi.org/10.1146/annurev-cellbio-101011-155833 24099085
PubMed Web of Science ®Google Scholar
CorsonTWCrewsCMMolecular understanding and modern application of traditional medicines: triumphs and trialsCell2007130 769 774 2507744 1:CAS:528:DC%2BD2sXhtV2ntL7L https://doi.org/10.1016/j.cell.2007.08.021 17803898
PubMed Web of Science ®Google Scholar
SinghSFrom exotic spice to modern drug?Cell2007130 765 768 1:CAS:528:DC%2BD2sXhtV2ntL7K https://doi.org/10.1016/j.cell.2007.08.024 17803897
PubMed Web of Science ®Google Scholar
HatcherHPlanalpRChoJTortiFMTortiSVCurcumin: from ancient medicine to current clinical trialsCell Mol Life Sci200865 1631 1652 1:CAS:528:DC%2BD1cXmslylsbY%3D https://doi.org/10.1007/s00018-008-7452-4 18324353
PubMed Web of Science ®Google Scholar
CuomoJAppendinoGDernASSchneiderEMcKinnonTPBrownMJTogniSDixonBMComparative absorption of a standardized curcuminoid mixture and its lecithin formulationJ Nat Prod201174 664 669 1:CAS:528:DC%2BC3MXjsVCksL0%3D https://doi.org/10.1021/np1007262 21413691
PubMed Web of Science ®Google Scholar
SteigerwaltRNebbiosoMAppendinoGBelcaroGCiammaichellaGCornelliULuzziRTogniSDugallMCesaroneMRIppolitoEErrichiBMLeddaAHosoiMCorsiMMeriva(R), a lecithinized curcumin delivery system, in diabetic microangiopathy and retinopathyPanminerva Med201254 11 16 1:STN:280:DC%2BC3s3mtValsQ%3D%3D 23241930
PubMed Web of Science ®Google Scholar
MazzolaniFPilot study of oral administration of a curcumin-phospholipid formulation for treatment of central serous chorioretinopathyClin Ophthalmol20126 801 806 3373230 1:CAS:528:DC%2BC38Xot12ktb0%3D 22701080
PubMedGoogle Scholar
LeddaABelcaroGDugallMLuzziRScocciantiMTogniSAppendinoGCiammaichellaGMeriva(R), a lecithinized curcumin delivery system, in the control of benign prostatic hyperplasia: a pilot, product evaluation registry studyPanminerva Med201254 17 22 1:STN:280:DC%2BC3s3mtValtg%3D%3D 23241931
PubMedGoogle Scholar
BelcaroGHosoiMPellegriniLAppendinoGIppolitoERicciALeddaADugallMCesaroneMRMaioneCCiammaichellaGGenovesiDTogniSA Controlled Study of a Lecithinized Delivery System of Curcumin (Meriva(R)) to Alleviate the Adverse Effects of Cancer TreatmentPhytother Res201428 3 444 450 1:CAS:528:DC%2BC2cXktV2gsrg%3D https://doi.org/10.1002/ptr.5014 23775598
PubMed Web of Science ®Google Scholar
BelcaroGCesaroneMRDugallMPellegriniLLeddaAGrossiMGTogniSAppendinoGEfficacy and safety of Meriva(R), a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patientsAlternative medicine review : a journal of clinical therapeutic201015 337 344
PubMed Web of Science ®Google Scholar
Di PierroFRapacioliGDi MaioEAAppendinoGFranceschiFTogniSComparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva((R))), nimesulide, and acetaminophenJ Pain Res20136 201 205 1:CAS:528:DC%2BC3sXltVKitL0%3D 23526055
PubMed Web of Science ®Google Scholar
JobinCBradhamCARussoMPJumaBNarulaASBrennerDASartorRBCurcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activityJ Immunol1999163 3474 3483 1:CAS:528:DyaK1MXlvV2lt7o%3D 10477620
PubMed Web of Science ®Google Scholar
SinghSAggarwalBBActivation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]J Biol Chem1995270 24995 25000 1:CAS:528:DyaK2MXovFWmsb8%3D https://doi.org/10.1074/jbc.270.42.24995 7559628
PubMedGoogle Scholar
AlamdariNO’NealPHasselgrenPOCurcumin and muscle wasting: a new role for an old drug?Nutrition200925 125 129 3258441 1:CAS:528:DC%2BD1MXntVyqsg%3D%3D https://doi.org/10.1016/j.nut.2008.09.002 19028079
PubMedGoogle Scholar
ThaloorDMillerKJGephartJMitchellPOPavlathGKSystemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injuryAm J Physiol1999277 C320 C329 1:CAS:528:DyaK1MXls1aitb4%3D 10444409
PubMed Web of Science ®Google Scholar
DunsmoreKEChenPGWongHRCurcumin, a medicinal herbal compound capable of inducing the heat shock responseCrit Care Med200129 2199 2204 1:CAS:528:DC%2BD3MXptVKrs78%3D https://doi.org/10.1097/00003246-200111000-00024 11700423
PubMed Web of Science ®Google Scholar
ChunKSKeumYSHanSSSongYSKimSHSurhYJCurcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activationCarcinogenesis200324 1515 1524 1:CAS:528:DC%2BD3sXnt1KjsrY%3D https://doi.org/10.1093/carcin/bgg107 12844482
PubMed Web of Science ®Google Scholar
ShehzadALeeYSMolecular mechanisms of curcumin action: signal transductionBioFactors201339 27 36 1:CAS:528:DC%2BC3sXjvVWquro%3D https://doi.org/10.1002/biof.1065 23303697
PubMed Web of Science ®Google Scholar
DavisJMMurphyEACarmichaelMDZielinskiMRGroschwitzCMBrownASGangemiJDGhaffarAMayerEPCurcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damageAmerican journal of physiology Regulatory, integrative and comparative physiology2007292 R2168 R2173 1:CAS:528:DC%2BD2sXmvF2ktrc%3D https://doi.org/10.1152/ajpregu.00858.2006 17332159
PubMed Web of Science ®Google Scholar
BuchfuhrerMJHansenJERobinsonTESueDYWassermanKWhippBJOptimizing the exercise protocol for cardiopulmonary assessmentJ Appl Physiol Respir Environ Exerc Physiol198355 1558 1564 1:STN:280:DyaL2c%2FmtFarsw%3D%3D 6643191
PubMed Web of Science ®Google Scholar
WassermanKBeaverWLWhippBJGas exchange theory and the lactic acidosis (anaerobic) thresholdCirculation199081 II14 II30 1:STN:280:DyaK3c7gs12ntw%3D%3D https://doi.org/10.1161/01.CIR.81.1.14 2403868
PubMedGoogle Scholar
NurenbergPGiddingsCJStray-GundersenJFleckensteinJLGonyeaWJPeshockRMMR imaging-guided muscle biopsy for correlation of increased signal intensity with ultrastructural change and delayed-onset muscle soreness after exerciseRadiology1992184 865 869 1:STN:280:DyaK38zns1aitQ%3D%3D https://doi.org/10.1148/radiology.184.3.1509081 1509081
PubMedGoogle Scholar
MalmCSjodinTLSjobergBLenkeiRRenstromPLundbergIEEkblomBLeukocytes, cytokines, growth factors and hormones in human skeletal muscle and blood after uphill or downhill runningJ Physiol2004556 983 1000 1664987 1:CAS:528:DC%2BD2cXktFCisr4%3D https://doi.org/10.1113/jphysiol.2003.056598 14766942
PubMed Web of Science ®Google Scholar
ClearyMAKimuraIFSitlerMRKendrickZVTemporal Pattern of the Repeated Bout Effect of Eccentric Exercise on Delayed-Onset Muscle SorenessJ Athl Train200237 32 36 164305 12937441
PubMed Web of Science ®Google Scholar
SmithLLMcKuneAJSempleSJSibandaESteelHAndersonRChanges in serum cytokines after repeated bouts of downhill runningApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme200732 233 240 1:CAS:528:DC%2BD2sXls12itrc%3D https://doi.org/10.1139/h06-106 17486164
PubMedGoogle Scholar
McNeilPLKhakeeRDisruptions of muscle fiber plasma membranes. Role in exercise-induced damageAm J Pathol1992140 1097 1109 1886518 1:STN:280:DyaK383lsV2huw%3D%3D 1374591
PubMed Web of Science ®Google Scholar
NosakaKClarksonPMChanges in indicators of inflammation after eccentric exercise of the elbow flexorsMed Sci Sports Exerc199628 953 961 1:STN:280:DyaK2s%2FisFOhtg%3D%3D https://doi.org/10.1097/00005768-199608000-00003 8871903
PubMed Web of Science ®Google Scholar
Orozco-LeviMGeaJLloretaJLFelezMMinguellaJSerranoSBroquetasJMSubcellular adaptation of the human diaphragm in chronic obstructive pulmonary diseaseEur Respir J199913 371 378 1:STN:280:DyaK1M7mtlGltQ%3D%3D https://doi.org/10.1183/09031936.99.13237199 10065684
PubMed Web of Science ®Google Scholar
ArtellsRNavarroADiazTMonzoMUltrastructural and immunohistochemical analysis of intestinal myofibroblasts during the early organogenesis of the human small intestineAnat Rec2011294 462 471 https://doi.org/10.1002/ar.21333
Google Scholar
JiangTXReidWDBelcastroARoadJDLoad dependence of secondary diaphragm inflammation and injury after acute inspiratory loadingAm J Respir Crit Care Med1998157 230 236 1:STN:280:DyaK1c7gs1SrsA%3D%3D https://doi.org/10.1164/ajrccm.157.1.9702051 9445304
PubMedGoogle Scholar
StraubVRafaelJAChamberlainJSCampbellKPAnimal models for muscular dystrophy show different patterns of sarcolemmal disruptionJ Cell Biol1997139 375 385 2139791 1:CAS:528:DyaK2sXmvV2guro%3D https://doi.org/10.1083/jcb.139.2.375 9334342
PubMed Web of Science ®Google Scholar
GoskerHRKubatBSchaartGvan der VusseGJWoutersEFScholsAMMyopathological features in skeletal muscle of patients with chronic obstructive pulmonary diseaseEur Respir J200322 280 285 1:STN:280:DC%2BD3svht1ygsA%3D%3D https://doi.org/10.1183/09031936.03.00012803 12952261
PubMed Web of Science ®Google Scholar
Gomez-CabreraMCDomenechERomagnoliMArduiniABorrasCPallardoFVSastreJVinaJOral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performanceAm J Clin Nutr200887 142 149 1:CAS:528:DC%2BD1cXmt1amsw%3D%3D 18175748
PubMed Web of Science ®Google Scholar
RistowMZarseKOberbachAKlotingNBirringerMKiehntopfMStumvollMKahnCRBluherMAntioxidants prevent health-promoting effects of physical exercise in humansProc Natl Acad Sci U S A2009106 8665 8670 2680430 1:CAS:528:DC%2BD1MXnt1SqsLs%3D https://doi.org/10.1073/pnas.0903485106 19433800
PubMed Web of Science ®Google Scholar
HandlerNJaegerWPuschacherHLeisserKErkerTSynthesis of novel curcumin analogues and their evaluation as selective cyclooxygenase-1 (COX-1) inhibitorsChem Pharm Bull200755 64 71 1:CAS:528:DC%2BD2sXjtlWmtr0%3D https://doi.org/10.1248/cpb.55.64 17202703
PubMed Web of Science ®Google Scholar
HongJBoseMJuJRyuJHChenXSangSLeeMJYangCSModulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenaseCarcinogenesis200425 1671 1679 1:CAS:528:DC%2BD2cXntFaiurk%3D https://doi.org/10.1093/carcin/bgh165 15073046
PubMed Web of Science ®Google Scholar
SchoenfeldBJDoes exercise-induced muscle damage play a role in skeletal muscle hypertrophy?J Strength Cond Res/National Strength & Conditioning Association201226 1441 1453 https://doi.org/10.1519/JSC.0b013e31824f207e
PubMed Web of Science ®Google Scholar
KoeberleANorthoffHWerzOCurcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1Mol Cancer Ther20098 2348 2355 1:CAS:528:DC%2BD1MXpvFCmsrY%3D https://doi.org/10.1158/1535-7163.MCT-09-0290 19671757
PubMed Web of Science ®Google Scholar
MeneghelAJVerlengiaRCrispAHAokiMSNosakaKDa MotaGRLopesCRMuscle damage of resistance-trained men after two bouts of eccentric bench press exerciseJ Strength Cond Res/National Strength & Conditioning Association2014 In press
Google Scholar
LeamyAWShuklaPMcAlexanderMACarrMJGhattaSCurcumin ((E, E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1Neurosci Lett2011503 157 162 1:CAS:528:DC%2BC3MXht1ans7nI https://doi.org/10.1016/j.neulet.2011.07.054 21855605
PubMedGoogle Scholar
YeonKYKimSAKimYHLeeMKAhnDKKimHJKimJSJungSJOhSBCurcumin produces an antihyperalgesic effect via antagonism of TRPV1J Dent Res201089 170 174 1:CAS:528:DC%2BC3cXitVKhtb4%3D https://doi.org/10.1177/0022034509356169 20040737
PubMed Web of Science ®Google Scholar
DasLVinayakMLong term effect of curcumin down regulates expression of TNF-alpha and IL-6 via modulation of ETS and NF-kappaB transcription factor in liver of lymphoma bearing miceLeukemia & lymphoma2014 In press
Google Scholar
FuYGaoRCaoYGuoMWeiZZhouELiYYaoMYangZZhangNCurcumin attenuates inflammatory responses by suppressing TLR4-mediated NF-kappaB signaling pathway in lipopolysaccharide-induced mastitis in miceInt Immunopharmacol201420 1 54 58 1:CAS:528:DC%2BC2cXntFOqu74%3D https://doi.org/10.1016/j.intimp.2014.01.024 24508537
PubMed Web of Science ®Google Scholar
BelcaroGCesaroneMRDugallMProduct evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritisPanminerva Med201052 55 62 1:STN:280:DC%2BC3cbisF2ltg%3D%3D 20657536
PubMed Web of Science ®Google Scholar

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Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial

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Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial

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