Exercise Capacity and Cardiovascular Adaptations to Aerobic Training Early After Stroke

REFERENCES

• Carr J, Mungovan SF, Shepherd R, Dean CM, Nordholm LA. Physical therapy in stroke rehabilita-tion: bases for Australian physiotherapists' choice of treatment. Physiother Pract. 1994;10:201–209.
   Google Scholar
• Wade D. Rehabilitation therapy after stroke. Lancet. 1999;354:177–178.
   PubMed Web of Science ®Google Scholar
• Gresham GE, Duncan PW, Stason WB, et al. Post-stroke Rehabilitation: Clinical Practice Guideline No. 16. Rockville, MD: US Department of Health and Human Services; 1995:247. AHCPR Publication No. 95–0662.
   Google Scholar
• Stewart DG. Stroke rehabilitation. 1. Epidemiologic aspects and acute management. Arch Phys Med Rehabil. 1999;80:S4–S7.
   Google Scholar
• Heart and Stroke Facts. Dallas, TX: American Heart Association; 2002.
   Google Scholar
• Gresham GE, Dawber TR. Residual disability in survivors of stroke. The Framingham Study. N Engl ] Med. 1975;293:954–956.
   PubMed Web of Science ®Google Scholar
• Jorgensen HS, Nakayama H, Raaschou HO, Vive-Larsen J, Steller M, Olsen TS. Outcome and time course of recovery in stroke. Part 1: Outcome. The Copenhagen Stroke Study. Arch Phys Med Rehabil. 1995;76:399–405.
   PubMed Web of Science ®Google Scholar
• Stineman MG, Granger CV. Epidemiology of stroke-related disability and rehabilitation outcome. Phys Med Rehabil Clin North Am. 1991;2:457–471.
   Google Scholar
• Roth EJ, Heinemann AW, Lovell LL, Harvey RL, McGuire JR, Diaz S. Impairment and disability: their relation during stroke rehabilitation. Arch Phys Med Rehabil. 1998;79:329–335.
   PubMed Web of Science ®Google Scholar
• Gresham GE, Phillips TF, Wolf PA, McNamara PM, Kannal WB, Dawber TR. Epidemiologic profile of long-term stroke disability: the Framingham Study. Arch Phys Med Rehabil. 1979;60:487–491.
   PubMed Web of Science ®Google Scholar
• Potempa K, Lopez M, Braun LT, Szidon P, Fogg L, Tincknell T. Physiological outcomes of aerobic exer-cise training in hemiparetic stroke patients. Stroke. 1995;26:101–105.
   PubMed Web of Science ®Google Scholar
• Macko RF, Smith GV, Dobrovolny CL, Sorkin JD, Goldberg AP, Silver KH. Treadmill training improves fitness reserve in chronic stroke patients. Arch Phys Med Rehabil. 2001;82:879–884.
   PubMed Web of Science ®Google Scholar
• Rimmer JFI, Riley B, Creviston T, Nicola T. Exercise training in a predominantly African-American group of stroke survivors. Med Sci Sport Exerc. 2000;32:1990–1996.
   PubMed Web of Science ®Google Scholar
• Chu KS, Eng JJ, Dawson AS, Harris JE, Ozkaplan A, Glyfadóttir S. Water-based exercise for cardio-vascular fitness in people with chronic stroke: a randomized controlled trial. Am] Phys Med Rehabil. 2004;85:870–874.
   Web of Science ®Google Scholar
• Skilbeck CE, Wade DT, Langton HR, Wood VE. Recovery after stroke. I Neurol Neurosurg Psych. 1983;46:5–8.
   PubMed Web of Science ®Google Scholar
• Biernaskie J, Chernenko G, Corbett D. Efficacy of rehabilitation experience declines with time after focal ischemic brain injury. I Neurosci. 2004;24:1245–1254.
   Google Scholar
• Blair SN, Kampert JB, Kohl HW. Influences of car-diorespiratory fitness and other precursors on car-diovascular disease and all-cause mortality in men and women. JAMA. 1996;276:205–210.
   Google Scholar
• Fagard RH. Physical fitness and hypertension. I Hypertens Suppl. 1993;11:47–52.
   Web of Science ®Google Scholar
• Hill JO, Drougas HJ, Peters JC. Physical activ-ity, fitness, and moderate obesity. In: Bouchard C Sr, Stephens T, eds. Physical Activity and Health. Champaign, IL: Human Kinetics Publishers Inc.; 1994:684–695.
   Google Scholar
• Stefanick ML, Mackey S, Sheehan M, Ellsworth N, Haskell W, Wood PD. Effects of diet and exercise in men and postmenopausal women with low levels of HDL cholesterol and high levels of LDL choles-terol. N Engl ] Med. 1998;339:12–20.
   PubMed Web of Science ®Google Scholar
• American College of Sports Medicine. Guidelines for Exercise Testing and Prescription. Baltimore, MD: Williams & Wilkins; 2000.
   Google Scholar
• Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974;54:75–103.
   PubMed Web of Science ®Google Scholar
• Bjuro T, Fugl-Meyer AR, Grimby G, Hook O, Lundgren B. Ergonomic studies of standardized domestic work in patients with neuromuscular handicap. Scand ] Rehabil Med. 1975;7:106–113.
   PubMedGoogle Scholar
• Bachynski-Cole M, Cumming GR. The cardiovascu-lar fitness of disabled patients attending occupa-tional therapy. Occup Then ] Res. 1985;5:233–242.
   Web of Science ®Google Scholar
• Fujitani J, Ishikawa T, Akai M, Kakurai S. Influence of daily activity on changes in physical fitness for people with post-stroke hemiplegia. Am] Phys Med Rehabil. 1999;78:540–544.
   Web of Science ®Google Scholar
• Ryan AS, Dobrovolny CL, Silver KH, Smith GV, Macko RF. Cardiovascular fitness after stroke: role of muscle mass and gait deficit severity. I Stroke Cerebrovasc Dis. 2000;9: 185–191.
   PubMedGoogle Scholar
• Holm& I, Astrand PO. Swimming training and max-imal oxygen uptake. Appl Physiol. 1972;33:510-513.
   Google Scholar
• Visintin M, Barbeau H. The effects of body weight support on the locomotor pattern of spastic paretic patients. Can Neurol Sci. 1989;16:315–325.
   PubMed Web of Science ®Google Scholar
• Wernig A, Muller S. Laufband locomotion with body weight support improved walking in per-sons with severe spinal cord injuries. Paraplegia. 1992;30:229–238.
   PubMedGoogle Scholar
• MacKay-Lyons M, Makrides L, Speth S. Effect of 15% body weight support on exercise capac-ity of adults without impairments. Phys Ther. 2001;81:1790–1800.
   PubMed Web of Science ®Google Scholar
• MacKay-Lyons M, Makrides L. Exercise capac-ity early after stroke. Arch Phys Med Rehabil. 2002;83:1697–1702.
   PubMed Web of Science ®Google Scholar
• Howley ET, Bassett DR, Welch HG. Criteria for maxi-mal oxygen uptake: review and commentary. Med Sci Sports Exerc. 1995;27:1292–1301.
   PubMed Web of Science ®Google Scholar
• da Cunha Filho IT, Lim PA, Quershy H, Henson H, Monga TN, Protas EJ. A comparison of regular rehabilitation with supported treadmill ambula-tion training for acute stroke patients.] Rehabil Res Develop. 2001;38:245–255.
   PubMed Web of Science ®Google Scholar
• Buchfuhrer MJ, Hansen JE, Robinson TE, Sue DY, Wasserman K, Whipp BJ. Optimizing the exercise protocol for cardiopulmonary assessment. Appl Physiol. 1983;55:1558–1564.
   PubMed Web of Science ®Google Scholar
• Suomimen HE, Heikkinen T, Parkatti T, Forsberg S, Kiiskinen A. Effects of lifelong physical train-ing on functional aging in men. Scand ] Soc Med. 1980;14(suppl):225–240.
   Google Scholar
• Astrand PO, Rodahl K. Textbook of Work Physiology. New York: McGraw-Hill; 1986.
   Google Scholar
• Vogel JA, Patton JF, Mello RP, Daniels WL. An analysis of aerobic capacity in a large United States population. Appl Physiol. 1986;60:494–500.
   PubMed Web of Science ®Google Scholar
• Borg GA. Psychophysical bases of perceived exer-tion. Med Sci Sports Exerc. 1982;14:377–381.
   PubMed Web of Science ®Google Scholar
• Londeree BR, Moeschberger ML. Influence of age and other factors on maximal heart rate. Cardiopulm Rehabil. 1984;4:44–49.
   Google Scholar
• Kelly JO, Kilbreadth SL, Davis GM, Zeman B, Raymond J. Cardiorespiratory fitness and walking ability in subacute stroke patients. Arch Phys Med Rehabil. 2003;84:1780–1785.
   PubMed Web of Science ®Google Scholar
• Wasserman K, Hansen JE, Sue DY, Casaburi R, Whipp BJ. Principles of Exercise Testing and Interpretation. Philadelphia, PA: Lippincott Williams & Wilkins; 1999.
   Google Scholar
• Shephard RJ. Physical training in the elderly. Arch Environ Health. 1986;5:515–533.
   Google Scholar
• Morris CK, Ueshima K, Kawaguchi T, Hideg A, Froelicher VF. The prognostic value of exercise capacity: a review of the literature. Am Heart J. 1991;122:1423–1430.
   PubMed Web of Science ®Google Scholar
• Rokey R, Rolak LA, Harati Y, Kutka N, Verani MS. Coronary artery disease in patients with cerebro-vascular disease: a prospective study. Ann Neurol. 1984;16:50–53.
   PubMed Web of Science ®Google Scholar
• Lseri LT, Smith RV, Evans MJ. Cardiovascular problems and functional evaluation in rehabilitation of hemiplegic patients. Chron Dis. 1968;21:423–434.
   PubMedGoogle Scholar
• Macko RF, Katzel LI, Yataco A, et al. Low-veloc-ity graded treadmill stress testing in hemiparetic stroke patients. Stroke. 1997;28:988–992.
   PubMed Web of Science ®Google Scholar
• Kurl S, Laukkanen JA, Rauramaa R, Lakka TA, Sivenius J, Salonen JT. Cardiorespiratory fitness and the risk of stroke in men. Arch Intern Med. 2003;163:1682–1688.
   PubMed Web of Science ®Google Scholar
• Bouchard C, Shephard RJ, Stephens T, Sutten JR, McPherson BD. Exercise, Fitness and Health: A Consensus of Current Knowledge. Champaign, IL: Human Kinetics; 1990.
   Google Scholar
• Roth E. Heart disease in patients with stroke. Part 1: classification and prevalence. Arch Phys Med Rehabil. 1993;74:752–760.
   PubMed Web of Science ®Google Scholar
• Roth E. Heart disease in patients with stroke. Part II: impact and implications for rehabilitation. Arch Phys Med Rehabil. 1994;75:94–101.
   PubMed Web of Science ®Google Scholar
• Young W, Gofman JW, Tandy S. Quantification of atherosclerosis within and between the coro-nary and cerebral vascular bed. Am ] Cardiol. 1960;6:300–308.
   Web of Science ®Google Scholar
• Mitchell JRA, Schwartz CI. Relationship between arterial disease in different sites. Br Med J. 1962;1:1293–1301.
   PubMedGoogle Scholar
• Wolf PA, Clagett GP, Easton JD, et al. Preventing ischemic stroke in patients with prior stroke and transient ischemic attack: a statement for health-care professionals from the stroke council of the American Heart Association. Stroke. 1999;30:1991–1994.
   PubMed Web of Science ®Google Scholar
• Hachinski V, Norris JW. The Acute Stroke. Philadelphia, PA: Davis; 1985.
   Google Scholar
• Di Pasquale G, Andreoli A, Carini G. Noninvasive screening for silent ischemic heart disease in patients with cerebral ischemia: use of dipyridam-ole-thallium myocardial imaging. Cerebrovasc Dis. 1991;1:31–37.
   Web of Science ®Google Scholar
• Sirna S, Biller J, Skorton DJ, Seabold JE. Cardiac evaluation of the patient with stroke. Stroke. 1990;21:14–23.
   PubMed Web of Science ®Google Scholar
• Tallman WT. Cardiovascular regulation and lesions of the central nervous system. Ann Neurol. 1985;18:1–12.
   PubMed Web of Science ®Google Scholar
• Clausen JP, Klausen K, Rasmussen B, Trap-Jensen J. Central and peripheral circulatory changes after training of the arms and legs. Am ] Physiol. 1973;225:675–682.
   PubMed Web of Science ®Google Scholar
• Camm Al. Chronotropic incompetence - Part 1: normal regulation of the heart rate. Clin Cardiol. 1996;19:424–428.
   PubMed Web of Science ®Google Scholar
• Vingerhoets F, Bogousslavsky J. Respiratory dysfunc-tion in stroke. Clin Chest Med. 1994;15:729–737.
   PubMedGoogle Scholar
• Harvey RL, Roth EJ, Heinemann AW, Lovell LL, McGuire JR, Diaz S. Stroke rehabilitation: clinical predictors of resource utilization. Arch Phys Med Rehabil. 1998;79:1349–1355.
   PubMed Web of Science ®Google Scholar
• Haas A, Rusk HA, Pelosof H, Adam JR. Respiratory function in hemiplegic patients. Arch Phys Med Rehabil. 1967;48:174–179.
   PubMedGoogle Scholar
• Fugl-Meyer AR, Grimby G. Respiration in tetraplegia and hemiplegia: a review. Int Rehabil Med. 1984;6:186–190.
   PubMedGoogle Scholar
• Fugl-Meyer A, Linderholm H, Wilson AF. Restrictive ventilatory dysfunction in stroke: its relation to loco-motor function. Scand ] Rehabil Med. 1983;(suppl 9):118–124.
   Google Scholar
• McComas AJ, Sica RE, Upton AR, Aquilera N. Functional changes in motoneurones of hemi-paretic patients. J Neurol Neurosurg Psychiatry. 1973;36:183–193.
   PubMed Web of Science ®Google Scholar
• Landin S, Hagenfeldt L, Saltin B, Wahren J. Muscle metabolism during exercise in hemiparetic patients. Clin Sci Mol Med. 1977;53:257–269.
   PubMedGoogle Scholar
• Jakobsson F, Edstrom L, Grimby L. Disuse of ante-rior tibial muscle during locomotion and increased proportion of type II fibers in hemiplegia. J Neurol Sci. 1991;105:49–56.
   Google Scholar
• De Deyne PG, Hafer-Macko CE, Ivey FM, Ryan AS, Macko RF. Muscle molecular phenotype after stroke is associated with gait speed. Musde Nerve. 2004;30:209–215.
   PubMed Web of Science ®Google Scholar
• Saltin B, Landin S. Work capacity, muscle strength, and SDH activity in both legs of hemiparetic patients and patients with Parkinson's disease. Scand J Clin Lab Invest. 1975;35:531–538.
   PubMed Web of Science ®Google Scholar
• Saunders DH, Greig CA, Young A, Mead GE. Physical Fitness Training for Stroke Patients (Cochrane Review). Chichester, UK: John Wiley & Sons, Ltd., The Cochrane Library; 2004.
   Google Scholar
• MacKay-Lyons M, Makrides L. Cardiovascular stress during stroke rehabilitation: Is the intensity ade-quate to induce a training effect? Arch Phys Med Rehabil. 2002;83: 1378–1383.
   PubMed Web of Science ®Google Scholar
• MacKay-Lyons M, Makrides L. Longitudinal chang-es in exercise capacity after stroke. Arch Phys Med Rehabil. 2004;85:1608–1612.
   PubMed Web of Science ®Google Scholar
• Taylor HL, Buskirk E, Henschel A. Maximal oxygen uptake as an objective measure of cardiorespiratory performance. J Appl Physiol. 1955;8:73–80.
   Google Scholar
• Savin WM, Haskell WL, Houston-Miller N, DeBusk RF. Improvements in aerobic capacity soon after myocar-dial infarction. J Cardiac Rehabil. 1981;1:337–342.
   Google Scholar
• Dressendorfer RH, Franklin BA, Cameron IL, Trahan KJ, Gordon S, Timmis GC. Exercise training frequen-cy in early post-infarction cardiac rehabilitation: influence on aerobic conditioning. J Cardiopulm Rehabil. 1995;15:269–276.
   PubMedGoogle Scholar
• Swain DP, Franklin BA. V02 reserve and the mini-mal intensity for improving cardiorespiratory fit-ness. Med Sci Sports Exerc. 2002;34:152–157.
   PubMed Web of Science ®Google Scholar
• Duncan P, Studenski S, Richards L, et al. Randomized clinical trial of therapeutic exercise in subacute stroke. Stroke. 2003;34:2173–2180.
   PubMed Web of Science ®Google Scholar
• Samitz G, Bachl N. Physical training programs and their effects on aerobic capacity and coronary risk profile in sedentary individuals. J Sports Med Phys Fitness. 1991;31:283–293.
   PubMed Web of Science ®Google Scholar
• Franklin BA, Besseghini I, Goldn LH. Low inten-sity physical conditioning: effects on patients with coronary heart disease. Arch Phys Med Rehabil. 1978;59:276–280.
   PubMed Web of Science ®Google Scholar
• Mertens DJ, Kavanagh T. Exercise training for patients with chronic atrial fibrillation. J Cardiopulm Rehabil. 1996;16:193–196.
   PubMedGoogle Scholar
• MacKay-Lyons M. Longitudinal Study of Changes in Exercise Capacity After Stroke. [doctoral thesis]. Department of Physiology and Biophysics, Faculty of Medicine, Dalhousie University; 2000.
   Google Scholar
• Lewis DA, Kamon E, Hodgson IL. Physiological dif-ferences between genders. Implications for sports conditioning. Sports Med. 1986;3:357–369.
   PubMed Web of Science ®Google Scholar
• MacKay-Lyons M, Howlett J, McDonald A, et al. Unpublished data. 2004.
   Google Scholar
• Saltin B. Physiological effects of physical condition-ing. Med Sci Sport. 1969;1:50–56.
   Google Scholar
• Fergueson RJ, Taylor AW, Cote P, et al. Skeletal mus-cle and cardiac changes with training in patients with angina pectoris. Am ] Physiol. 1982;243: H830–H836.
   Google Scholar
• Madsen K, Pedersen PK, Djurhuus MS, Klitgaard NA. Effects of detraining on endurance capacity and metabolic changes during prolonged endur-ance exercise. J Appl Physiol. 1993;43:1444–1451.
   Google Scholar
• da Cunha Filho IT, Lim PA, Quershy H, Henson H, Monga TN, Protas EJ. Gait outcomes after acute stroke rehabilitation with supported treadmill train-ing: a randomized controlled pilot study. Arch Phys Med Rehabil. 2002;83:1258–1265.
   PubMed Web of Science ®Google Scholar
• Roth EJ, Mueller K, Green D. Cardiovascular response to physical therapy in stroke rehabilita-tion. NeuroRehabil. 1992;2:7–15.
   Google Scholar
• Lellamo F, Legramante JM, Raimondi G, et al. Effects of isokinetic, isotonic and isometric submaximal exercise on heart rate and blood pressure. Eur ] Appl Physiol. 1997;75:89–96.
   PubMed Web of Science ®Google Scholar
• Hankey GJ, Warlow CR Treatment and second-ary prevention of stroke: evidence, costs and effects on individuals and populations. Lancet. 1999;354:1457–1463.
   PubMed Web of Science ®Google Scholar
• Antiplatelet Trialists' Collaboration. Secondary pre-vention of vascular disease by prolonged antiplate-let treatment. Br Med J. 1988;296:320–331.
   PubMed Web of Science ®Google Scholar