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Perspective

Glial progenitor cell transplantation and the generation of chimeric animal models with human brain cells: implications for novel therapeutics

, PhD
Pages 1639-1646 | Published online: 26 Nov 2009

Bibliography

  • Legrand N, Weijer K, Hergen Spits H. experimental model for the study of the human immune system. Methods Mol Biol 2008;415:65-82
  • Pearson T, Greiner DL, Shultz LD. Creation of humanized mice to study human immunity. Curr Protocols Immunol 2008;81
  • Habiro K, Skyes M, Yang G-M. Induction of human T-Cell tolerance to pig xenoantigens via thymus transplantation in mice with an established human immune system. Am J Transplant 2009;9:1324-9
  • Zhang H, Region-specific differentiation of neural tube-derived neuronal restricted progenitor cells after heterotopic transplantation. Proc Natl Acad Sci 2007;97:13366-71
  • Pow DV, Differential expression of the GABA transporters GAT-1 and GAT-3 in brains of rats, cats, monkeys and humans. Cell Tissue Res 2005;320:379-92
  • Williams SM, Glial glutamate transporter expression patterns in brains from multiple mammalian species. Glia 2005;49:520-41
  • Nedergaard M, Ransom B, Goldman SA. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 2003;26:523-30
  • Goldman SA, Schanz S, Windrem MS. Stem cell-based strategies for treating pediatric disorders of myelin. Hum Mol Genet 2008;17:76-83
  • Windrem MS, Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated lesions of the rat brain. J Neurosci Res 2002;69:966-75
  • Roy NS, Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J Neurosci 1999;9:9986-95
  • Scolding NJ, Rayner PJ, Sussman J, A proliferative adult human oligodendrocyte progenitor. Neuroreport 1995;15:441-5
  • Scolding NJ, Rayner PJ, Compston DA. Identification of A2B5-positive putative oligodendrocyte progenitor cells and A2B5-positive astrocytes in adult human white matter. Neuroscience 1999;89:1-4
  • Emborg ME, GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplant 2008;17:383-95
  • Suzuki M, GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS. PLoS One 2009;8:1-14
  • Hooshmand MJ, Sontag CJ, Uchida N, Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery. PLoS One 2009;4:e5871
  • Ke Y, Early response of endogenous adult neural progenitor cells to acute spinal cord injury in mice. Stem Cells 2006;24:1011-19
  • Jin K, Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum. Mol Cell Neurosci 2003;24:171-89
  • Jin K, Evidence for stroke-induced neurogenesis in the human brain. Proc Natl Acad Sci USA 2006;103(35):13198-202
  • Curtis MA, Connor B, Faull RL. Neurogenesis in the diseased adult human brain–new therapeutic strategies for neurodegenerative diseases. Cell Cycle 2003;2(5):428-30
  • Rice AC, Proliferation and neuronal differentiation of mitotically active cells following traumatic brain injury. Exp Neurol 2003;183(2):406-17
  • Tattersfield AS, Neurogenesis in the striatum of the quinolinic acid lesion model of huntington's disease. Neuroscience 2004;127:319-32
  • Munoz-Sanjuan I, Brivanlou A-H. Neural induction, the default model and embryonic stem cells. Nat Rev Neurosci 2002;3:271-80
  • Joannides AJ, Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain 2007;130:1263-75
  • Setoguchi T, Traumatic injury-induced BMP7 expression in the adult rat spinal cord. Brain Res 2001;921:219-25
  • Setoguchi T, Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor. Exp Neurol 2004;189:33-44
  • Windrem MS, Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell 2008;2:553-65
  • Givogri MI, Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. J Neurosci 2006;26:3109-19
  • Blakemore WL, Gilson JM, Crang JA. Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cells. J Neurosci Res 2000;61:288-94
  • Akesson E, Long-term survival, robust neuronal differentiation, and extensive migration of human forebrain stem/progenitor cells transplanted to the adult rat dorsal root ganglion cavity. Cell Transplant 2008;17:1115-23
  • Givogri MI, Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. J Neurosci 2002;26:3109-19
  • Archer DR, Cuddon PA, Lipsitz D, Duncan ID. Myelination of the canine central nervous system by glial cell transplantation: a model for repair of human myelin disease. Nat Med 1997;3:54-9
  • Perez-Bouza A, Glaser T, Brustle O. ES cell-derived glial precursors contribute to remyelination in acutely demyelinated spinal cord lesions. Brain pathology. Brain Pathol 2005;15:208-16
  • Chang A, Premyelinating oligodendrocytes in chronic lesionsof multiple sclerosis. NEJM 2002;346:165-73
  • Franklin RJM. Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci 2002;3:705-14
  • Kuhlmann T, Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 2008;131:1749-58
  • Goldman, US7,524,491B2; 2009
  • Popko B, Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin. Cell 1987;48:713-21
  • Readhead C, Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell 1987;48:703-12
  • Roach A, Boylan K, Horvath S, Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice. Cell 1983;34:799-806
  • Gout O, Gansmuller A, Baumann N, Gumpel M. Remyelination by transplanted oligodendrocytes of a demyelinated lesion in the spinal cord of the adult shiverer mouse. Neurosci Lett 1988;87:195-9
  • Low HP, Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice. J Neurol Sci 2009;276:133-37
  • Yandava DY, Billinghurst LL, Snyder EY. “Global” cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. Proc Natl Acad Sci 1999;96:7029-34
  • Weiss, US6497872C1; 2002
  • Goldman, US7468277B2; 2002
  • Reubinoff, US7504257B2; 2002
  • Snyder BJ, Olanow CW. Stem cell treatment for Parkinson's disease: an update for 2005. Curr Opin Neurol 2005;18(4):376-85
  • Krystkowiak P, Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with huntington's disease. PLoS One 2007;2:e166
  • Peschanski M, Bachoud-Lévi AC, Hantraye P. Integrating fetal neural transplants into a therapeutic strategy: the example of huntington's disease. Brain 2004;127:1219-28
  • Kordower JH, Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies. J Comp Neurol 1996;370:203-30
  • Lindvall O, Evidence for long-term survival and function of dopaminergic grafts in progressive parkinson's disease. Ann Neurol 1994;35:172-80
  • Tepavcević V, Blakemore WF. Haplotype matching is not an essential requirement to achieve remyelination of demyelinating CNS lesions. Glia 2006;54:880-90
  • Nait-Oumesmar B, Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors. Proc Natl Acad Sci USA 2007;104:4694-9
  • Nait-Oumesmar B, Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination. Eur J Neurosci 1999;11:4357-66
  • Lepore AC, Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci 2006;11:1294-301
  • Guzman R, Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci 2007;104:10211-16
  • Neri M, Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking. Stem Cells 2008; 26:505-16
  • Schäfer R, The use of clinically approved small particles of iron oxide (SPIO) for labeling of mesenchymal stem cells aggravates clinical symptoms in experimental autoimmune encephalomyelitis and influences their in vivo distribution. Cell Transplant 2008;17:923-41
  • Schäfer R, Labeling of human mesenchymal stromal cells with superparamagnetic iron oxide leads to a decrease in migration capacity and colony formation ability. Cytotherapy 2009;11:68-78
  • Duncan ID, Griffiths IR, Munz M. ‘SHAKING PUPS’: a disorder of central myelination in the spaniel dog. III. Quantitative aspects of glia and myelin in the spinal cord and optic nerve. Neuropathol Appl Neurobiol 1983;9:355-68
  • Fauza DO, Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida. Surgery 2008;144:367-73
  • Bjugstad KB, Human neural stem cells migrate along the nigrostriatal pathway in a primate model of parkinson's disease. Exp Neurology 2008;211:362-9
  • Goldman SA, Schanz S, Windrem MS. Stem cell-based strategies for treating pediatric disorders of myelin. Hum Mol Genet 2008;17:76-83

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