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Patent Evaluations

3-Hydroxy-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-ones as new HIV-1 integrase inhibitors WO2011046873 A1

Pages 1799-1804 | Published online: 06 Oct 2011

Bibliography

  • Moyle G, Gatell J, Perno CF, Potential for new antiretrovirals to address unmet needs in the management of HIV-1 infection. AIDS Patient Care STDs 2008;22:459-71
  • Steigbigel RT, Cooper DA, Kumar PN, Raltegravir with optimized background therapy for resistant HIV-1 infection. N Engl J Med 2008;359:339-54
  • Ramkumar K, Neamati N. Raltegravir: the evidence of its therapeutic value in HIV-1 infection. Core Evid 2010;4:131-47
  • Al-Mawsawi LQ, Al-Safi RI, Neamati N. Anti-infectives: clinical progress of HIV-1 integrase inhibitors. Expert Opin Emerg Drugs 2008;13:213-25
  • Zolopa A, Mullen M, Berger D, 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, USA, 143LB 2007
  • Min S, Song I, Borland J, Pharmacokinetics and safety of S/GSK1349572, a next-generation HIV integrase inhibitor, in healthy volunteers.. Antimicrob Agents Chemother 2010;54:254-8
  • Mascolinli M, Kort R. 5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention: summary of key research and implications for policy and practice - clinical sciences. Int AIDS Soc 2010;13(Suppl 1):S3
  • Garvey EP, Johns BA, Gartland MJ, The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother 2008;52:901-8
  • Kobayashi M, Yoshinaga T, Seki T, In vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor. Antimicrob Agents Chemother 2011;55:813-21
  • Garrido C, Soriano V, Geretti AM, Resistance associated mutations to dolutegravir (S/GSK1349572) in HIV-infected patients – Impact of HIV subtypes and prior raltegravir experience. Antiviral Res 2011;90:164-7
  • Bristol-Myers Squibb Co. HIV integrase inhibitors. WO2008154246; 2008
  • Bristol-Myers Squibb Co. Bridged heterocycles as HIV integrase inhibitors. WO2009117540; 2009
  • Merck & Co., Inc. HIV integrase inhibitors. WO2010042391; 2010
  • Merck & Co., Inc. HIV integrase inhibitors. WO2010042392; 2010
  • Merck & Co., Inc. Bridged compounds as HIV integrase inhibitors. WO2010088167; 2010
  • Merck & Co. Bridged compounds as HIV integrase inhibitors. WO2010088167; 2010
  • Serrao E, Odde S, Ramkumar K, Neamati N. Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology 2009;6:25
  • Bristol-Myers Squibb Co. HIV integrase inhibitors. WO2011046873; 2011
  • Bristol-Myers Squibb Co. Preparation of tetrahydrocarbolines for treatment of HIV infection and AIDS. US20050267105 A1; 2005
  • Engelman A, Craigie R. Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity. J Virol 1995;69:5908-11
  • Johnson VA, Byington RT. Infectivity assay. In: Aldovini A, Walker B, editors. Techniques in HIV research. Stockton Press; New York: 1990
  • Hare S, Gupta SS, Valkov E, Retroviral intasome assembly and inhibition of DNA strand transfer. Nature 2010;464:232-7
  • Pendri A, Meanwell NA, Peese KM, Walker MA. New first and second generation inhibitors of human immunodeficiency virus-1 integrase. Expert Opin Ther Patents 2011;21:1173-89

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