204
Views
13
CrossRef citations to date
0
Altmetric
Original Research

Influence of lipoplex surface charge on siRNA delivery: application to the in vitro downregulation of CXCR4 HIV-1 co-receptor

, PhD, , , , , , , , & show all
Pages 973-985 | Published online: 07 Jan 2013

Bibliography

  • Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 2008;319:921-6
  • Zhou H, Xu M, Huang Q, et al. Genome-scale RNAi screen for host factors required for HIV replication. Cell. Host Microbe 2008;4:495-504
  • Li M, Li H, Rossi JJ. RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy. Ann N Y Acad Sci 2006;1082:172-9
  • Anderson J, Akkina R. HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector. AIDS Res Ther 2005;2:1
  • Zhou N, Fang J, Mukhtar M, et al. Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther 2004;11:1703-12
  • Tamhane M, Akkina R. Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance. AIDS Res Ther 2008;5:16
  • Shim MS, Kwon YJ. Efficient and targeted delivery of siRNA in vivo. FEBS J 2010;277:4814-27
  • White PJ. Barriers to successful delivery of short interfering RNA after systemic administration. Clin Exp Pharmacol Physiol 2008;35:1371-6
  • Zimmermann TS, Lee AC, Akinc A, et al. RNAi-mediated gene silencing in non-human primates. Nature 2006;441:111-14
  • Castanotto D, Rossi JJ. The promises and pitfalls of RNA-interference-based therapeutics. Nature 2009;457:426-33
  • Akhtar S, Benter I. Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity. Adv Drug Deliv Rev 2007;59:164-82
  • Mescalchin A, Detzer A, Wecke M, et al. Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: novel options by phosphorothioate-stimulated delivery. Expert Opin Biol Ther 2007;7:1531-8
  • Zaghloul EM, Viola JR, Zuber G, et al. Formulation and delivery of splice-correction antisense oligonucleotides by amino acid modified polyethylenimine. Mol Pharm 2010;7:652-63
  • Masotti A, Mossa G, Cametti C, et al. Comparison of different commercially available cationic liposome-DNA lipoplexes: parameters influencing toxicity and transfection efficiency. Colloids Surf B Biointerfaces 2009;68:136-44
  • Barteau B, Chevre R, Letrou-Bonneval E, et al. Physicochemical parameters of non-viral vectors that govern transfection efficiency. Curr Gene Ther 2008;8:313-23
  • Midoux P, Breuzard G, Gomez JP, et al. Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes. Curr Gene Ther 2008;8:335-52
  • Felgner PL, Barenholz Y, Behr JP, et al. Nomenclature for synthetic gene delivery systems. Hum Gene Ther 1997;8:511-12
  • Tarahovsky YS. Cell transfection by DNA-lipid complexes - lipoplexes. Biochemistry (Mosc) 2009;74:1293-304
  • Hofland HE, Shephard L, Sullivan SM. Formation of stable cationic lipid/DNA complexes for gene transfer. Proc Natl Acad Sci USA 1996;93:7305-9
  • Thierry AR, Lunardi-Iskandar Y, Bryant JL, et al. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proc Natl Acad Sci USA 1995;92:9742-6
  • Zhu N, Liggitt D, Liu Y, et al. Systemic gene expression after intravenous DNA delivery into adult mice. Science 1993;261:209-11
  • Thierry AR, Vives E, Richard JP, et al. Cellular uptake and intracellular fate of antisense oligonucleotides. Curr Opin Mol Ther 2003;5:133-8
  • Lavigne C, Thierry AR. Enhanced antisense inhibition of human immunodeficiency virus type 1 in cell cultures by DLS delivery system. Biochem Biophys Res Commun 1997;237:566-71
  • Zelphati O, Szoka FC Jr. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci USA 1996;93:11493-8
  • Lv H, Zhang S, Wang B, et al. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 2006;114:100-9
  • Plank C, Mechtler K, Szoka FC Jr, et al. Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther 1996;7:1437-46
  • Pirollo KF, Rait A, Zhou Q, et al. Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system. Cancer Res 2007;67:2938-43
  • Hassan A, Tian Y, Zheng W, et al. Small interfering RNA-mediated functional silencing of vasopressin V2 receptors in the mouse kidney. Physiol Genomics 2005;21:382-8
  • Hassani Z, Lemkine GF, Erbacher P, et al. Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels. J Gene Med 2005;7:198-207
  • Yano J, Hirabayashi K, Nakagawa S, et al. Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer. Clin Cancer Res 2004;10:7721-6
  • Dritschilo A, Huang CH, Rudin CM, et al. Phase I study of liposome-encapsulated c-raf antisense oligodeoxyribonucleotide infusion in combination with radiation therapy in patients with advanced malignancies. Clin Cancer Res 2006;12:1251-9
  • Takeshita F, Minakuchi Y, Nagahara S, et al. Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 2005;102:12177-82
  • Thierry AR, Dritschilo A. Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity. Nucleic Acids Res 1992;20:5691-8
  • Lavigne C, Yelle J, Sauve G, et al. Lipid-based delivery of combinations of antisense oligodeoxynucleotides for the in vitro inhibition of HIV-1 replication. AAPS PharmSci 2001;3:E7
  • Lisziewicz J, Sun D, Weichold FF, et al. Antisense oligodeoxynucleotide phosphorothioate complementary to Gag mRNA blocks replication of human immunodeficiency virus type 1 in human peripheral blood cells. Proc Natl Acad Sci USA 1994;91:7942-6
  • Lavigne C, Thierry AR. Specific subcellular localization of siRNAs delivered by lipoplex in MCF-7 breast cancer cells. Biochimie 2007;89:1245-51
  • Meryet-Figuieres M, Resina S, Lavigne C, et al. Inhibition of PAI-1 expression in breast cancer carcinoma cells by siRNA at nanomolar range. Biochimie 2007;89:1228-33
  • Resina S, Prevot P, Thierry AR. Physico-chemical characteristics of lipoplexes influence cell uptake mechanisms and transfection efficacy. PLoS One 2009;4:e6058
  • Thierry AR, Abes S, Resina S, et al. Comparison of basic peptides- and lipid-based strategies for the delivery of splice correcting oligonucleotides. Biochim Biophys Acta 2006;1758:364-74
  • Chackerian B, Long EM, Luciw PA, et al. HIV-1 co-receptors participates in post-entry stages of the virus replication cycle and function in SIV infection. J Virol 1997;71:3932-9
  • Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996;381:661-6
  • Tavitian B, Marzabal S, Boutet V, et al. Characterization of a synthetic anionic vector for oligonucleotide delivery using in vivo whole body dynamic imaging. Pharm Res 2002;19:367-76
  • Schmutz M, Durand D, Debin A, et al. DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage. Proc Natl Acad Sci USA 1999;96:12293-8
  • Lavigne C, Rastogi A, Schmutz M, et al. Supramolecular auto organization of DNA and cationic lipid with cardiolipin in anionic particles of high gene transfer capacities. Unpublished Results
  • Felgner PL, Gadek TR, Holm M, et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987;84:7413-17
  • Ortiz A, Killian JA, Verkleij AJ, et al. Membrane fusion and the lamellar-to-inverted-hexagonal phase transition in cardiolipin vesicle systems induced by divalent cations. Biophys J 1999;77:2003-14
  • Almsherqi Z, Hyde S, Ramachandran M, et al. Cubic membranes: a structure-based design for DNA uptake. J R Soc Interface 2008;5:1023-9
  • Aleman LM, Doench J, Sharp PA. Comparison of siRNA-induced off-target RNA and protein effects. RNA 2007;13:385-95
  • Doench JG, Petersen CP, Sharp PA. siRNAs can function as miRNAs. Genes Dev 2003;17:438-42
  • Anderson J, Banerjea A, Akkina R. Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides 2003;13:303-12
  • Marchini C, Montani M, Amici A, et al. Structural stability and increase in size rationalize the efficiency of lipoplexes in serum. Langmuir 2009;25:3013-21
  • Pozharski EV, MacDonald RC. Single lipoplex study of cationic lipoid-DNA, self-assembled complexes. Mol Pharm 2007;4:962-74

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.