Embryonic stem cells as a treatment for macular degeneration

Bibliography

• Klein R, Klein BE, Linton KL. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology 1992;99(6):933-43
   PubMed Web of Science ®Google Scholar
• Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282(5391):1145-7
   PubMed Web of Science ®Google Scholar
• Wenkel H, Streilein JW. Analysis of immune deviation elicited by antigens injected into the subretinal space. Invest Ophthalmol Vis Sci 1998;39(10):1823-34
   PubMed Web of Science ®Google Scholar
• Harman AM, Fleming PA, Hoskins RV, et al. Development and aging of cell topography in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci 1997;38(10):2016-26
   PubMed Web of Science ®Google Scholar
• Del Priore LV, Kuo YH, Tezel TH. Age-related changes in human RPE cell density and apoptosis proportion in situ. Invest Ophthalmol Vis Sci 2002;43(10):3312-18
   PubMed Web of Science ®Google Scholar
• Boulton M, Moriarty P, Jarvis-Evans J, et al. Regional variation and age-related changes of lysosomal enzymes in the human retinal pigment epithelium. Br J Ophthalmol 1994;78(2):125-9
   PubMed Web of Science ®Google Scholar
• Marmorstein AD. The polarity of the retinal pigment epithelium. Traffic 2001;2(12):867-72
   PubMed Web of Science ®Google Scholar
• Stamer WD, Bok D, Hu J, et al. Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement. Invest Ophthalmol Vis Sci 2003;44(6):2803-8
   PubMed Web of Science ®Google Scholar
• Carlson A, Bok D. Polarity of 11-cis retinal release from cultured retinal pigment epithelium. Invest Ophthalmol Vis Sci 1999;40(2):533-7
   PubMed Web of Science ®Google Scholar
• Marmor MF. Mechanisms of normal retinal adhesion in retina. St. Louis, Mosby; 2005. p. 1891-908
   Google Scholar
• Strauss O. The retinal pigment epithelium in visual function. Physiol Rev 2005;85(3):845-81
   PubMed Web of Science ®Google Scholar
• Bok D. The retinal pigment epithelium: a versatile partner in vision. J Cell Sci Suppl 1993;17:189-95
   PubMedGoogle Scholar
• Lamb TD, Pugh EN Jr. Dark adaptation and the retinoid cycle of vision. Prog Retin Eye Res 2004;23(3):307-80
   PubMed Web of Science ®Google Scholar
• Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004;122(4):564-72
   PubMed Web of Science ®Google Scholar
• Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 2004;122(4):598-614
   PubMed Web of Science ®Google Scholar
• Kunze C, Elsner AE, Beausencourt E, et al. Spatial extent of pigment epithelial detachments in age-related macular degeneration. Ophthalmology 1999;106(9):1830-40
   PubMed Web of Science ®Google Scholar
• Shen JK, Dong A, Hackett SF, et al. Oxidative damage in age-related macular degeneration. Histol Histopathol 2007;22(12):1301-8
   PubMed Web of Science ®Google Scholar
• Anderson DH, Radeke MJ, Gallo NB, et al. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 2010;29(2):95-112
   PubMed Web of Science ®Google Scholar
• Zhou J, Jang YP, Kim SR, et al. Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium. Proc Natl Acad Sci USA 2006;103(44):16182-7
   PubMed Web of Science ®Google Scholar
• Sparrow JR, Vollmer-Snarr HR, Zhou J, et al. A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J Biol Chem 2003;278(20):18207-13
   PubMed Web of Science ®Google Scholar
• Sarks JP, Sarks SH, Killingsworth MC, et al. Evolution of geographic atrophy of the retinal pigment epithelium. Eye (Lond) 1988;2(Pt 5):552-77
   PubMedGoogle Scholar
• Sohocki MM, Daiger SP, Bowne SJ, et al. Prevalence of mutations causing retinitis pigmentosa and other inherited retinopathies. Hum Mutat 2001;17(1):42-51
   PubMed Web of Science ®Google Scholar
• Koenekoop RK, Lopez I, Den Hollander AI, et al. Genetic testing for retinal dystrophies and dysfunctions: benefits, dilemmas and solutions. Clin Experiment Ophthalmol 2007;35(5):473-85
   PubMed Web of Science ®Google Scholar
• Blacharski P, et al. Stargardt macular degeneration. In: Newsome DA, editor. Retinal dystrophies and degeneration. Raven Press, New York; 1988. Available from: http://ghr.nlm.nih.gov/condition/stargardt-macular-degeneration
   Google Scholar
• Flood MT, Gouras P, Kjeldbye H, et al. Growth characteristics and ultrastructure of human retinal pigment epithelium in vitro. Invest Ophthalmol Vis Sci 1980;19(11):1309-20
   PubMed Web of Science ®Google Scholar
• Gouras P, Flood MT, Kjeldbye H, et al. Transplantation of cultured human retinal epithelium to Bruch's membrane of the owl monkey's eye. Curr Eye Res 1985;4(3):253-65
   PubMed Web of Science ®Google Scholar
• Gouras P, Flood MT, Kjeldbye H, et al. Transplantation of cultured human retinal cells to monkey retina. An Acad Bras Cienc 1984;56(4):431-43
   PubMed Web of Science ®Google Scholar
• Lopez R, Gouras P, Kjeldbye K, et al. Transplanted retinal pigment epithelium modifies the retinal degeneration in the RCS rat. Invest Ophthalmol Vis Sci 1989;30(3):586-8
   PubMed Web of Science ®Google Scholar
• Vollrath D, Feng W, Duncan JL, et al. Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk. Proc Natl Acad Sci USA 2001;98(22):12584-9
   PubMed Web of Science ®Google Scholar
• Lawrence JM, Keeagan DJ, Muir EM, et al. Transplantation of Schwann cell line clones secreting GDNF or BDNF into retinas of dystrophic Royal College of Surgeons rats. Invest Ophthalmol Vis Sci 2004;45(1):267-74
   PubMed Web of Science ®Google Scholar
• Lund RD, Wang S, Lu B, et al. Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease. Stem Cells 2007;25(3):602-11
   PubMed Web of Science ®Google Scholar
• Wang S, Girman S, Lu B, et al. Long-term vision rescue by human neural progenitors in a rat model of photoreceptor degeneration. Invest Ophthalmol Vis Sci 2008;49(7):3201-6
   PubMed Web of Science ®Google Scholar
• Lu B, Wang S, Girman S, et al. Human adult bone marrow-derived somatic cells rescue vision in a rodent model of retinal degeneration. Exp Eye Res 2010;91(3):449-55
   PubMed Web of Science ®Google Scholar
• Wang S, Lu B, Wood P, et al. Grafting of ARPE-19 and Schwann cells to the subretinal space in RCS rats. Invest Ophthalmol Vis Sci 2005;46(7):2552-60
   PubMed Web of Science ®Google Scholar
• Peyman GA, Blinder KJ, Paris CL, et al. A technique for retinal pigment epithelium transplantation for age-related macular degeneration secondary to extensive subfoveal scarring. Ophthalmic Surg 1991;22(2):102-8
   PubMedGoogle Scholar
• Del Priore LV, Geng L, Tezel TH, et al. Extracellular matrix ligands promote RPE attachment to inner Bruch's membrane. Curr Eye Res 2002;25(2):79-89
   PubMed Web of Science ®Google Scholar
• Tezel TH, Kaplan HJ, Del Priore LV, et al. Fate of human retinal pigment epithelial cells seeded onto layers of human Bruch's membrane. Invest Ophthalmol Vis Sci 1999;40(2):467-76
   PubMed Web of Science ®Google Scholar
• Gullapalli VK, Sugino IK, Van Patten Y, et al.l. Impaired RPE survival on aged submacular human Bruch's membrane. Exp Eye Res 2005;80(2):235-48
   PubMed Web of Science ®Google Scholar
• Yamamoto S, Du J, Gouras P, et al. Retinal pigment epithelial transplants and retinal function in RCS rats. Invest Ophthalmol Vis Sci 1993;34(11):3068-75
   PubMed Web of Science ®Google Scholar
• Zhang XD, Bok D, et al. Transplantation of retinal pigment epithelial cells and immune response in the subretinal space. Invest Ophthalmol Vis Sci 1998;39(6):1021-7
   PubMed Web of Science ®Google Scholar
• Crafoord S, Algvere PV, Seregard S, et al. Long-term outcome of RPE allografts to the subretinal space of rabbits. Acta Ophthalmol Scand 1999;77(3):247-54
   PubMedGoogle Scholar
• Gabrielian K, Oganesian A, Patel SC, et al. Cellular response in rabbit eyes after human fetal. RPE cell transplantation. Graefes Arch Clin Exp Ophthalmol 1999;237(4):326-35
   PubMed Web of Science ®Google Scholar
• Del Priore LV, Ishida O, Johnson EW, et al. Triple immune suppression increases short-term survival of porcine fetal retinal pigment epithelium xenografts. Invest Ophthalmol Vis Sci 2003;44(9):4044-53
   PubMed Web of Science ®Google Scholar
• Crafoord S, Algvere PV, Kopp ED, et al. Cyclosporine treatment of RPE allografts in the rabbit subretinal space. Acta Ophthalmol Scand 2000;78(2):122-9
   PubMedGoogle Scholar
• Binder S, Stolba U, Krebs I, et al. Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: a pilot study. Am J Ophthalmol 2002;133(2):215-25
   PubMed Web of Science ®Google Scholar
• Assadoullina A. Harvesting efficacy and viability of retinal pigment epithelial cells in aspirates from posterior retinal areas – a study on human eyes. In: Binder S, editor. The macula: diagnosis, treatment and future trends. Springer, New York; 2004. p. 45-50
   Google Scholar
• Phillips SJ, Sadda SR, Tso MO, et al. Autologous transplantation of retinal pigment epithelium after mechanical debridement of Bruch's membrane. Curr Eye Res 2003;26(2):81-8
   PubMed Web of Science ®Google Scholar
• Gouras P, Algvere P, et al. Retinal cell transplantation in the macula: new techniques. Vision Res 1996;36(24):4121-5
   PubMed Web of Science ®Google Scholar
• Del Priore LV, Kaplan HJ, Tezel TH, et al. Retinal pigment epithelial cell transplantation after subfoveal membranectomy in age-related macular degeneration: clinicopathologic correlation. Am J Ophthalmol 2001;131(4):472-80
   PubMed Web of Science ®Google Scholar
• van Meurs JC, Ter Averst E, Hofland LJ, et al. Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes. Br J Ophthalmol 2004;88(1):110-13
   PubMed Web of Science ®Google Scholar
• Joussen AM, Heussen FM, Joeres S, et al. Autologous translocation of the choroid and retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol 2006;142(1):17-30
   PubMed Web of Science ®Google Scholar
• Tsukahara I, Ninomiya S, Castellarin A, et al. Early attachment of uncultured retinal pigment epithelium from aged donors onto Bruch's membrane explants. Exp Eye Res 2002;74(2):255-66
   PubMed Web of Science ®Google Scholar
• Tezel TH, Del Priore LV. Repopulation of different layers of host human Bruch's membrane by retinal pigment epithelial cell grafts. Invest Ophthalmol Vis Sci 1999;40(3):767-74
   PubMed Web of Science ®Google Scholar
• Lund RD, Kwan AS, Keeagan DJ, et al. Cell transplantation as a treatment for retinal disease. Prog Retin Eye Res 2001;20(4):415-49
   PubMed Web of Science ®Google Scholar
• Wong IY, Poon MW, Pang RT, et al. Promises of stem cell therapy for retinal degenerative diseases. Graefes Arch Clin Exp Ophthalmol 2011;249(10):1439-48
   PubMed Web of Science ®Google Scholar
• Rezai KA, Kohen L, Wiedemann P, et al. Iris pigment epithelium transplantation. Graefes Arch Clin Exp Ophthalmol 1997;235(9):558-62
   PubMed Web of Science ®Google Scholar
• Rezai KA, Lappas A, Farrokh-Siar L, et al. Iris pigment epithelial cells of Long-Evans rats demonstrate phagocytic activity. Exp Eye Res 1997;65(1):23-9
   PubMed Web of Science ®Google Scholar
• Thumann G, Bartz-Schmidt KU, Heimann K, et al. Phagocytosis of rod outer segments by human iris pigment epithelial cells in vitro. Graefes Arch Clin Exp Ophthalmol 1998;236(10):753-7
   PubMed Web of Science ®Google Scholar
• Abe T, Yoshida M, Tomita H, et al. Auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration: short-term results. Tohoku J Exp Med 2000;191(1):7-20
   PubMed Web of Science ®Google Scholar
• Tamai M. Autologous iris pigment transplantation in age related macular degeneration. In: Das T, editor. Retina: current practice and future trends. Paras, Hyderabad; India; 1999. p. 151-61
   Google Scholar
• Thumann G, Aisenbrey S, Schraermeyer U, et al. Transplantation of autologous iris pigment epithelium after removal of choroidal neovascular membranes. Arch Ophthalmol 2000;118(10):1350-5
   PubMed Web of Science ®Google Scholar
• Aisenbrey S, Lafaut BA, Szurman P, et al. Iris pigment epithelial translocation in the treatment of exudative macular degeneration: a 3-year follow-up. Arch Ophthalmol 2006;124(2):183-8
   PubMed Web of Science ®Google Scholar
• Cai H, Shin MC, Tezel TH, et al. Use of iris pigment epithelium to replace retinal pigment epithelium in age-related macular degeneration: a gene expression analysis. Arch Ophthalmol 2006;124(9):1276-85
   PubMed Web of Science ®Google Scholar
• Tropepe V, Coles BL, Chiasson BJ, et al. Retinal stem cells in the adult mammalian eye. Science 2000;287(5460):2032-6
   PubMed Web of Science ®Google Scholar
• Ahmad I, Das AV, James J, et al. Neural stem cells in the mammalian eye: types and regulation. Semin Cell Dev Biol 2004;15(1):53-62
   PubMed Web of Science ®Google Scholar
• MacNeil A, Pearson RA, Maclaren RE, et al. Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye. Stem Cells 2007;25(10):2430-8
   PubMed Web of Science ®Google Scholar
• Coles BL, Angenieux B, Inoue T, et al. Facile isolation and the characterization of human retinal stem cells. Proc Natl Acad Sci USA 2004;101(44):15772-7
   PubMed Web of Science ®Google Scholar
• Ratajczak MZ, Kucia M, Reca R, et al. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004;18(1):29-40
   PubMed Web of Science ®Google Scholar
• Li Y, Atmaca-Sonmez P, Schanie CL, et al. Endogenous bone marrow derived cells express retinal pigment epithelium cell markers and migrate to focal areas of RPE damage. Invest Ophthalmol Vis Sci 2007;48(9):4321-7
   PubMed Web of Science ®Google Scholar
• Hoffman LM, Carpenter MK. Characterization and culture of human embryonic stem cells. Nat Biotechnol 2005;23(6):699-708
   PubMed Web of Science ®Google Scholar
• Leveillard T, Mohand-Said S, Sahel JA. Retinal repair by transplantation of photoreceptor precursors. Med Sci (Paris) 2007;23(3):240-2
   PubMed Web of Science ®Google Scholar
• MacLaren RE, Pearson RA, Macneil A, et al. Retinal repair by transplantation of photoreceptor precursors. Nature 2006;444(7116):203-7
   PubMed Web of Science ®Google Scholar
• Schraermeyer U, Thumann G, Luther T, et al. Subretinally transplanted embryonic stem cells rescue photoreceptor cells from degeneration in the RCS rats. Cell Transplant 2001;10(8):673-80
   PubMed Web of Science ®Google Scholar
• Haruta M. Embryonic stem cells: potential source for ocular repair. Semin Ophthalmol 2005;20(1):17-23
   PubMedGoogle Scholar
• Arnhold S, Klein H, Semkoval I, et al. Neurally selected embryonic stem cells induce tumor formation after long-term survival following engraftment into the subretinal space. Invest Ophthalmol Vis Sci 2004;45(12):4251-5
   PubMed Web of Science ®Google Scholar
• Klimanskaya I, Hipp J, Rezai KA, et al. Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics. Cloning Stem Cells 2004;6(3):217-45
   PubMedGoogle Scholar
• Lund RD, Wang S, Klimanskaya I, et al. Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats. Cloning Stem Cells 2006;8(3):189-99
   PubMedGoogle Scholar
• Lu B, Malcuit C, Wang S, et al. Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells 2009;27(9):2126-35
   PubMed Web of Science ®Google Scholar
• Schwartz SD, Hubschman JP, Heilwell G, et al. Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet 2012;379(9817):713-20
   PubMed Web of Science ®Google Scholar
• Abe T, Tomita H, Kano T, et al. Autologous iris pigment epithelial cell transplantation in monkey subretinal region. Curr Eye Res 2000;20(4):268-75
   PubMed Web of Science ®Google Scholar
• Wongpichedchai S, Weiter JJ, Weber P, et al. Comparison of external and internal approaches for transplantation of autologous retinal pigment epithelium. Invest Ophthalmol Vis Sci 1992;33(12):3341-52
   PubMed Web of Science ®Google Scholar
• Bhatt NS, Newsome DA, Fenech T, et al. Experimental transplantation of human retinal pigment epithelial cells on collagen substrates. Am J Ophthalmol 1994;117(2):214-21
   PubMed Web of Science ®Google Scholar
• Singhal S, Vemuganti GK. Primary adult human retinal pigment epithelial cell cultures on human amniotic membranes. Indian J Ophthalmol 2005;53(2):109-13
   PubMedGoogle Scholar
• Farrokh-Siar L, Rezai KA, Patel SC, et al. Cryoprecipitate: an autologous substrate for human fetal retinal pigment epithelium. Curr Eye Res 1999;19(2):89-94
   PubMed Web of Science ®Google Scholar
• Hadlock T, Singh S, Vacanti JP, et al. Ocular cell monolayers cultured on biodegradable substrates. Tissue Eng 1999;5(3):187-96
   PubMedGoogle Scholar
• Thomson RC, Giordano GG, Collier JH, et al. Manufacture and characterization of poly(alpha-hydroxy ester) thin films as temporary substrates for retinal pigment epithelium cells. Biomaterials 1996;17(3):321-7
   PubMed Web of Science ®Google Scholar
• Tezcaner A, Bugra K, Hasirci V. Retinal pigment epithelium cell culture on surface modified poly(hydroxybutyrate-co-hydroxyvalerate) thin films. Biomaterials 2003;24(25):4573-83
   PubMed Web of Science ®Google Scholar
• Capeans C, Pinerio A, Pardo M, et al. Amniotic membrane as support for human retinal pigment epithelium (RPE) cell growth. Acta Ophthalmol Scand 2003;81(3):271-7
   PubMedGoogle Scholar
• Ohno-Matsui K, Ichinosae S, Nakahama K, et al. The effects of amniotic membrane on retinal pigment epithelial cell differentiation. Mol Vis 2005;11:1-10
   PubMed Web of Science ®Google Scholar
• Ohno-Matsui K, Mori K, Ichinose S, et al. In vitro and in vivo characterization of iris pigment epithelial cells cultured on amniotic membranes. Mol Vis 2006;12:1022-32
   PubMed Web of Science ®Google Scholar
• Gullapalli VK, Sugino IK, Van Patten Y, et al. Retinal pigment epithelium resurfacing of aged submacular human Bruch's membrane. Trans Am Ophthalmol Soc 2004;102:123-37; discussion 137-8
   PubMedGoogle Scholar
• Beutel J, Greulich L, Luke M, et al. Inner limiting membrane as membranous support in RPE sheet-transplantation. Graefes Arch Clin Exp Ophthalmol 2007;245(10):1469-73
   PubMed Web of Science ®Google Scholar
• Srivastava GK, Martin L, Singh AK, et al. Elastin-like recombinamers as substrates for retinal pigment epithelial cell growth. J Biomed Mater Res A 2011;97(3):243-50
   PubMed Web of Science ®Google Scholar
• Nicolini J, Kiilgaard JF, Wiencke AK, et al. The anterior lens capsule used as support material in RPE cell-transplantation. Acta Ophthalmol Scand 2000;78(5):527-31
   PubMedGoogle Scholar
• Lu B, Zhu D, Hinton D, et al. Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells. Biomed Microdevices 2012
   PubMed Web of Science ®Google Scholar
• Sugino IK, Gullapalli VK, Sun Q, et al. Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane. Invest Ophthalmol Vis Sci 2011;52(3):1345-58
   PubMed Web of Science ®Google Scholar
• Sugino IK, Rapista A, Sun Q, et al. A method to enhance cell survival on Bruch's membrane in eyes affected by age and age-related macular degeneration. Invest Ophthalmol Vis Sci 2011;52(13):9598-609
   PubMed Web of Science ®Google Scholar