Targeting Brn-3b in breast cancer therapy

Bibliography

• VERRIJZER CP, VAN DER VLIET PC: POU domain transcription factors. Biochim. Biophys. Acta (1993) 1173:1-21.
   PubMedGoogle Scholar
• PHILLIPS K, LUISI B: The virtuoso of versatility: POU proteins that flex to fit. J. Mol. Biol. (2000) 302:1023-1039.
   PubMed Web of Science ®Google Scholar
• LATCHMAN DS: POU family transcription factors in the nervous system. J. Cell. Physiol. (1999) 179:126-133.
   PubMed Web of Science ®Google Scholar
• LEVINE M, HOEY T: Homeobox proteins as sequence-specific transcription factors. Cell (1998) 55:537-540.
   Google Scholar
• RYAN AK, ROSENFELD MG: POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev. (1997) 11:1207-1225.
   PubMedGoogle Scholar
• XIANG M, ZHOU L, MACKE JP et al.: The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. J. Neurosci. (1995) 15:4762-4785.
   PubMed Web of Science ®Google Scholar
• KLEMM JD, ROULD MA, AURORA R, HERR W, PABO CO: Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell (1994) 77:21-32.
   PubMed Web of Science ®Google Scholar
• GRUBER CA, RHEE JM, GLEIBERMAN A, TURNER EE: POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolution. Mol. Cell. Biol. (1997) 17:2391-2400.
   PubMedGoogle Scholar
• HERR W, STURM RA, CLERC RG et al.: The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. (1998) 2:1513-1516.
   Google Scholar
• HE X, TREACY MN, SIMMONS DM, INGRAHAM HA, SWANSON LW, ROSENFELD M: Expression of a large family of POU-domain regulatory genes in mammalian brain development. Nature (1999) 340:35-41.
   Google Scholar
• LILLYCROP KA, BUDHRAM-MAHADEO V, LAKIN ND et al.: A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Res. (1992) 20:5093-5096.
   PubMedGoogle Scholar
• NINKINA NN, STEVENS GE, WOOD JN, RICHARDSON W: A novel Brn3-like POU transcription factor expressed in subsets of rat sensory and spinal cord neurons. Nucleic Acids Res. (1993) 21:3175-3182.
   PubMedGoogle Scholar
• TREACY MN, HE X, ROSENFELD M: I-POU: a POU-domain protein that inhibits neuron-specific gene activation. Nature (1991) 350:577-584.
   PubMedGoogle Scholar
• XIANG M, ZHOU L, PENG YW, EDDY RL, SHOWS TB, NATHANS J: Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells. Neuron (1993) 11:689-701.
   PubMedGoogle Scholar
• TURNER EE, JENNE KJ, ROSENFELD M: Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron (1994) 12:205-218.
   PubMedGoogle Scholar
• BUDHRAM-MAHADEO V, MOORE A, MORRIS PJ et al.: The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis. Int. J. Biochem. Cell Biol. (2001) 33:1027-1039.
   PubMedGoogle Scholar
• BUDHRAM-MAHADEO V, NDISANG D, WARD T, WEBER BL, LATCHMAN D: The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells. Oncogene (1999) 18:6684-6691.
   PubMedGoogle Scholar
• THEIL T, ZECHNER U, KLETT C, ADOLPH S, MOROY T: Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes. Cytogenet. Cell Genet. (1994) 66:267-271.
   PubMedGoogle Scholar
• THEIL T, MCLEAN-HUNTER S, ZORNIG M, MOROY T: Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a. Nucleic Acids Res. (1993) 21:5921-5929.
   PubMedGoogle Scholar
• GAN L, WANG SW, HUANG Z, KLEIN W: POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification. Dev. Biol. (1999) 210:469-480.
   PubMedGoogle Scholar
• XIANG M: Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev. Biol. (1998) 197:155-169.
   PubMedGoogle Scholar
• BUDHRAM-MAHADEO V, LILLYCROP KA, LATCHMAN D: The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors. Neurosci. Lett. (1995) 185:48-51.
   PubMedGoogle Scholar
• BUDHRAM-MAHADEO V, THEIL T, MORRIS PJ, LILLYCROP KA, MOROY T, LATCHMAN D: The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells. Nucleic Acids Res. (1994) 22:3092-3098.
   PubMedGoogle Scholar
• SMITH MD, DAWSON SJ, LATCHMAN D: Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor. J. Biol. Chem. (1997) 272:1382-1388.
   PubMedGoogle Scholar
• DENNIS JH, BUDHRAM-MAHADEO V, LATCHMAN D: The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells. Oncogene (2001) 20:4961-4971.
   PubMedGoogle Scholar
• LEE SA, NDISANG D, PATEL C et al.: Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter. Cancer Res. (2005) 65:3072-3080.
   PubMed Web of Science ®Google Scholar
• IRSHAD S, PEDLEY RB, ANDERSON J, LATCHMAN DS, BUDHRAM-MAHADEO V: The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo. J. Biol. Chem. (2004) 279:21617-21627.
   PubMedGoogle Scholar
• STARITA LM, PARVIN J: The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr. Opin. Cell Biol. (2003) 15:345-350.
   PubMed Web of Science ®Google Scholar
• WELCSH PL, OWENS KN, KING M: Insights into the functions of BRCA1 and BRCA2. Trends Genet. (2000) 16:69-74.
   PubMed Web of Science ®Google Scholar
• THOMPSON D, EASTON D: Cancer Incidence in BRCA1 mutation carriers. J. Natl. Cancer Inst. (2002) 94:1358-1365.
   PubMed Web of Science ®Google Scholar
• THOMPSON ME, JENSEN RA, OBERMILLER PS, PAGE DL, HOLT J: Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat. Genet. (1995) 9:444-450.
   PubMed Web of Science ®Google Scholar
• MAGDINIER F, RIBIERAS S, LENOIR GM, FRAPPART L, DANTE R: Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region. Oncogene (1998) 17:3169-3176.
   PubMedGoogle Scholar
• SAMADY L, DENNIS J, BUDHRAM-MAHADEO V, LATCHMAN D: Activation of CDK4 gene expr.ession in human breast cancer cells by the Brn-3b POU family tTranscription factor. Cancer Biol. Ther. (2004) 3:317-323.
   PubMed Web of Science ®Google Scholar
• VARGAS-ROIG LM, GAGO FE, TELLO O, AZNAR JC, CIOCCA D: Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy. Int. J. Cancer (1998) 79:468-475.
   PubMed Web of Science ®Google Scholar
• VARGAS-ROIG LM, FANELLI MA, LOPEZ LA et al.: Heat shock proteins and cell proliferation in human breast cancer biopsy samples. Cancer Detect. Prev. (1997) 21:441-451.
   PubMedGoogle Scholar
• OESTERREICH S, WENG CN, QIU M, HILSENBECK SG, OSBORNE CK, FUQUA S: The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res. (1993) 53:4443-4448.
   PubMed Web of Science ®Google Scholar
• HANSEN RK, PARRA I, LEMIEUX P, OESTERREICH S, HILSENBECK SG, FUQUA S: Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells. Breast Cancer Res. Treat. (1999) 56:187-196.
   PubMed Web of Science ®Google Scholar
• LEMIEUX P, OESTERREICH S, LAWRENCE JA et al.: The small heat shock protein hsp27 increases invasiveness but decreases motility of breast cancer cells. Invasion Metastasis (1997) 17:113-123.
   PubMedGoogle Scholar
• OESTERREICH S, WENG CN, QIU M, HILSENBECK SG, OSBORNE CK, FUQUA S: The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res. (1993) 53:4443-4448.
   PubMed Web of Science ®Google Scholar
• SAMADY L, DENNIS JD, BUDHRAM-MAHADEO V, LATCHMAN D: Expression of plakoglobin in breast cancer cells is inversely correlated with Brn-3b which represses its expression. Int. J. Cancer (2005). In press.
   Google Scholar
• BUCHNER A, OBERNEDER R, RIESENBERG R, KEIDITSCH E, HOFSTETTER A: Expression of plakoglobin in renal cell carcinoma. Anti-Cancer Res. (1998) 18:4231-4235.
   PubMedGoogle Scholar
• BUDHRAM-MAHADEO V, PARKER M, LATCHMAN D: POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Mol. Cell. Biol. (1998) 18:1029-1041.
   PubMedGoogle Scholar
• KLINGE C: Estrogen receptor interaction with estrogen response elements. Nucleic Acids Res. (2001) 29:2905-2919.
   PubMed Web of Science ®Google Scholar
• KUSHNER PJ, WEBB P, UHT RM, LIU M-M, PRICE RH: Estrogen receptor action through target genes with classical and alternative response elements. Pure Appl. Chem. (2003) 75:1757-1769.
   Google Scholar
• HART LL, DAVIE J: The estrogen receptor: more than the average transcription factor. Biochem. Cell Biol. (2002) 80:335-341.
   PubMedGoogle Scholar
• SOMMER S, FUQUA S: Estrogen receptor and breast cancer. Semin. Cancer Biol. (2001) 11:339-352.
   PubMed Web of Science ®Google Scholar
• CIOCCA DR, FANELLI M: Estrogen Receptors and cell proliferation in breast cancer. Trends Endocrinol. Metab. (1997) 8:313-321.
   PubMed Web of Science ®Google Scholar
• HOWELL SJ, JOHNSTON SR, HOWELL A: The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer. Best. Pract. Res. Clin. Endocrinol. Metab. (2004) 18:47-66.
   PubMed Web of Science ®Google Scholar
• ROBERTSON J: Estrogen receptor downregulators: new antihormonal therapy for advanced breast cancer. Clin. Ther. (2002) 24(Suppl. A):A17-A30.
   Google Scholar
• HUDIS C: Current status and future directions in breast cancer therapy. Clin. Breast Cancer (2003) 4(Suppl. 2):S70-S75.
   PubMedGoogle Scholar
• MILES D, VON MINCKWITZ G, SEIDMAN A: Combination versus sequential single-agent therapy in metastatic breast cancer. Oncologist (2002) 7(Suppl. 6):13-19.
   PubMed Web of Science ®Google Scholar
• RUBENS R: Treatment of metastatic breast cancer and its complications. Curr. Opin. Oncol. (1991) 3:1029-1034.
   PubMedGoogle Scholar
• BECKER F, MURTHI K, SMITH C et al.: A three-hybrid approach to scanning the proteome for targets of small molecule kinase inhibitors. Chem. Biol. (2004) 11:211-223.
   PubMed Web of Science ®Google Scholar
• WINSSINGER N, FICARRO S, SCHULTZ PG, HARRIS J: Profiling protein function with small molecule microarrays. Proc. Natl. Acad. Sci. USA (2002) 99:11139-11144.
   PubMed Web of Science ®Google Scholar
• STOCKWELL BR, HAGGARTY SJ, SCHREIBER S: High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications. Chem. Biol. (1999) 6:71-83.
   PubMed Web of Science ®Google Scholar
• PADDISON PJ, HANNON G: RNA interference: the new somatic cell genetics? Cancer Cell (2002) 2:17-23.
   PubMed Web of Science ®Google Scholar
• HANNON G: RNA interference. Nature (2002) 418:244-251.
   PubMed Web of Science ®Google Scholar
• DYKXHOORN DM, NOVINA CD, SHARP P: Killing the messenger: short RNAs that silence gene expression. Nat. Rev. Mol. Cell. Biol. (2003) 4:457-467.
   PubMed Web of Science ®Google Scholar
• HENDRIE PC, RUSSELL D: Gene targeting with viral vectors. Mol. Ther. (2005) 12:9-17.
   PubMed Web of Science ®Google Scholar
• LUNDSTROM K: Latest development in viral vectors for gene therapy. Trends Biotech. (2003) 21:117-122.
   PubMed Web of Science ®Google Scholar
• SMITH AE: Viral vectors in gene therapy. Ann. Rev. Microbiol. (1995) 49:807-838.
   PubMed Web of Science ®Google Scholar
• LING X, ARLINGHAUS R: Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice. Cancer Res. (2005) 65:2532-2536.
   PubMed Web of Science ®Google Scholar
• ANDERSON LM, SWAMINATHAN S, ZACKON I, TAJUDDIN AK, THIMMAPAYA B, WEITZMAN S: Adenovirus-mediated tissue-targeted expression of the HSVtk gene for the treatment of breast cancer. Gene Ther. (1999) 6:854-864.
   PubMedGoogle Scholar