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Volume 10, Issue 1

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 10, Issue 1 (2006)

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Expert Opinion on Therapeutic Targets, Volume 10, Issue 1 (2006)

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Interview

Article

A new therapeutic target for atherosclerosis treatment: interview with Uday Saxena

Interviewed by Emma Quigley

Pages: 1-3

Published online: 27 Jan 2006

AbstractforA new therapeutic target for atherosclerosis treatment: interview with Uday Saxena | Full Text | PDF (38.1 KB)

503 Views
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Review

Article

Targeting vascular endothelial growth factor in angina therapy

Munir Boodhwani, Basel Ramlawi, Roger J Laham & Frank W Sellke

Pages: 5-14

Published online: 27 Jan 2006

AbstractforTargeting vascular endothelial growth factor in angina therapy | Full Text | References | PDF (162.8 KB)

37 Views
1 CrossRef citations
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Article

Targeting Brn-3b in breast cancer therapy

Vishwanie S Budhram-Mahadeo & David S Latchman

Pages: 15-25

Published online: 27 Jan 2006

AbstractforTargeting Brn-3b in breast cancer therapy | Full Text | References | PDF (171 KB)

128 Views
13 CrossRef citations
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Article

The role of cellular flice inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer

Amanda Dutton, Lawrence S Young & Paul G Murray

Pages: 27-35

Published online: 27 Jan 2006

AbstractforThe role of cellular flice inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer | Full Text | References | PDF (122.6 KB)

193 Views
39 CrossRef citations
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Article

Targeting chaperones in transformed systems – a focus on Hsp90 and cancer

Gabriela Chiosis

Pages: 37-50

Published online: 27 Jan 2006

AbstractforTargeting chaperones in transformed systems – a focus on Hsp90 and cancer | Full Text | References | PDF (183.8 KB)

177 Views
65 CrossRef citations
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Article

Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML

Øystein Bruserud, Camilla Stapnes, Karl Johan Tronstad, Anita Ryningen, Nina Ånensen & Bjørn Tore Gjertsen

Pages: 51-68

Published online: 27 Jan 2006

AbstractforProtein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML | Full Text | References | PDF (231.9 KB)

257 Views
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Article

The small-molecule immune response modifier imiquimod – its mode of action and clinical use in the treatment of skin cancer

Michael P Schön & Margarete Schön

Pages: 69-76

Published online: 27 Jan 2006

AbstractforThe small-molecule immune response modifier imiquimod – its mode of action and clinical use in the treatment of skin cancer | Full Text | References | PDF (112.3 KB)

134 Views
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Article

Targeting Aurora kinases in ovarian cancer

Siqing Fu, Wei Hu, John J Kavanagh & Robert C Bast Jr

Pages: 77-85

Published online: 27 Jan 2006

AbstractforTargeting Aurora kinases in ovarian cancer | Full Text | References | PDF (111.3 KB)

119 Views
16 CrossRef citations
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Article

From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer

Bharat B Aggarwal, Haruyo Ichikawa, Prachi Garodia, Priya Weerasinghe, Gautam Sethi, Indra D Bhatt, Manoj K Pandey, Shishir Shishodia & Muraleedharan G Nair

Pages: 87-118

Published online: 27 Jan 2006

AbstractforFrom traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer | Full Text | References | PDF (510.7 KB)

828 Views
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Article

Adipose targets for obesity drug development

Olivier Boss & Nils Bergenhem

Pages: 119-134

Published online: 27 Jan 2006

AbstractforAdipose targets for obesity drug development | Full Text | References | PDF (197.1 KB)

170 Views
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Article

Shp2 as a therapeutic target for leptin resistance and obesity

Gen-Sheng Feng

Pages: 135-142

Published online: 27 Jan 2006

AbstractforShp2 as a therapeutic target for leptin resistance and obesity | Full Text | References | PDF (146.8 KB)

289 Views
29 CrossRef citations
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Article

Targeting matrix metalloproteases to improve cutaneous wound healing

Meilang Xue, Nghia TV Le & Christopher J Jackson

Pages: 143-155

Published online: 27 Jan 2006

AbstractforTargeting matrix metalloproteases to improve cutaneous wound healing | Full Text | References | PDF (225.4 KB)

476 Views
104 CrossRef citations
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Article

Targeting the PTPome in human disease

Lutz Tautz, Maurizio Pellecchia & Tomas Mustelin

Pages: 157-177

Published online: 27 Jan 2006

AbstractforTargeting the PTPome in human disease | Full Text | References | PDF (289.5 KB)

394 Views
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Technology Evaluation

Article

Transcreener™: screening enzymes involved in covalent regulation

Robert G Lowery & Karen Kleman-Leyer

Pages: 179-190

Published online: 27 Jan 2006

AbstractforTranscreener™: screening enzymes involved in covalent regulation | Full Text | References | PDF (176 KB)

118 Views
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Key Paper Evaluation

Article

Ceramide as a target in emphysema

PETRACHE I, NATARAJAN V, ZHEN L et al.: Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat. Med. (2005) 11:491-498.

Sheila A Doggrell

Pages: 191-194

Published online: 27 Jan 2006

AbstractforCeramide as a target in emphysema | Full Text | References | PDF (58.2 KB)

40 Views
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