The role of inflammation in the pathogenesis of lung cancer

Bibliography

• Jermal A, Bray F, Center MM, Global cancer statistics. CA Cancer J Clin 2011;61:69-90
   Google Scholar
• Hussain SP, Harris CC. Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 2007;15:2373-80
   Google Scholar
• Ekbom A, Helmick C, Zack M, Adami HO. Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 1990;323:1228-33
   PubMed Web of Science ®Google Scholar
• Thorsteinsdottir S, Gudjonsson T, Nielsen OH, Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis. Nat Rev Gastroenterol Hepatol 2011; published online 7 June 2011; doi:10.1038/nrgastro.2011.96
   Google Scholar
• Ullman TA, Itzkowitz SH. Intestinal inflammation and cancer. Gastroenterology 2011;140:1807-16
   PubMed Web of Science ®Google Scholar
• Schiffman M, Wentzensen N, Wacholder S, Human papillomavirus testing in the prevention of cervical cancer. J Natl Cancer Inst 2011;103:368-83
   PubMedGoogle Scholar
• Wan SG, Taccioli C, Jiang Y, Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer 2011;129:331-45
   Google Scholar
• de Martel C, Plummer M, Parsonnet J, Helicobacter species in cancers of the gallbladder and extrahepatic biliary tract. Br J Cancer 2009;100:194-9
   PubMed Web of Science ®Google Scholar
• Das M, Garlick DS, Greiner DL, Davis RJ. The role of JNK in the development of hepatocellular carcinoma. Genes Dev 2011;25:634-45
   PubMed Web of Science ®Google Scholar
• Polk DB, Peek RM Jr. Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer 2010;10:403-14
   PubMed Web of Science ®Google Scholar
• De Nunzio C, Kramer G, Marberger M, The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation. Eur Urol 2011;60:106-17
   PubMed Web of Science ®Google Scholar
• Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006;118:3030-44
   PubMed Web of Science ®Google Scholar
• Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008;454:436-44
   PubMed Web of Science ®Google Scholar
• Rook GA, Dalgleish A. Infection, immunoregulation, and cancer. Immunol Rev 2011;240:141-59
   Google Scholar
• Kundu JK, Surh YJ. Inflammation: gearing the journey to cancer. Mutat Res 2008;659:15-30
   PubMed Web of Science ®Google Scholar
• Coussens LM, Raymond WW, Bergers G, Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 1999;13:1382-97
   PubMed Web of Science ®Google Scholar
• Cosper PF, Leinwand LA. Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Res 2011;71:1710-20
   PubMed Web of Science ®Google Scholar
• Losa D, Chanson M, Crespin S. Connexins as therapeutic targets in lung disease. Expert Opin Ther Targets 2011; published online 17 May 2011; doi:10.1517/14728222.2011.584875
   Google Scholar
• Alberg AJ, Ford JG, Samet JM; American College of Chest Physicians. Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 2007;132:29S-55S
   PubMed Web of Science ®Google Scholar
• Engels EA. Inflammation in the development of lung cancer: epidemiological evidence. Expert Rev Anticancer Ther 2008;8:605-15
   PubMed Web of Science ®Google Scholar
• Houghton AM, Mouded M, Shapiro SD, Common origins of lung cancer and COPD. Nat Med. 2008;14:1023-4
   Google Scholar
• Moghaddam SJ, Li H, Cho SN, Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model. Am J Respir Cell Mol Biol 2009;40:443-53
   PubMed Web of Science ®Google Scholar
• Punturieri A, Szabo E, Croxton TL, Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. J Natl Cancer Inst 2009;101:554-9
   PubMed Web of Science ®Google Scholar
• Oh SS, Chang SC, Cai L, Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers. Int J Cancer 2010;127:2169-82
   Google Scholar
• Goldkorn T, Filosto S. Lung injury and cancer: mechanistic insights into ceramide and EGFR signaling under cigarette smoke. Am J Respir Cell Mol Biol 2010;43:259-68
   Google Scholar
• Schwartz L, Guais A, Chaumet-Riffaud P, Carbon dioxide is largely responsible for the acute inflammatory effects of tobacco smoke. Inhal Toxicol 2010;22:543-51
   PubMed Web of Science ®Google Scholar
• Cheng CY, Hsieh HL, Sun CC, IL-1beta induces urokinase-plasminogen activator expression and cell migration through PKCalpha, JNK1/2, and NF-kappaB in A549 cells. J Cell Physiol 2009;219:183-93
   PubMed Web of Science ®Google Scholar
• Cheng CY, Kuo CT, Lin CC, IL-1beta induces expression of matrix metalloproteinase-9 and cell migration via a c-Src-dependent, growth factor receptor transactivation in A549 cells. Br J Pharmacol 2010;160:1595-610
   PubMedGoogle Scholar
• Antony GK, Dudek AZ. Interleukin 2 in cancer therapy. Curr Med Chem 2010;17:3297-302
   PubMed Web of Science ®Google Scholar
• Gougeon ML, Chiodi F. Impact of gamma-chain cytokines on T cell homeostasis in HIV-1 infection: therapeutic implications. J Intern Med 2010;267:502-14
   PubMedGoogle Scholar
• Jin GH, Hirano T, Murakami M. Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation. Int Immunol 2008;20:783-9
   PubMed Web of Science ®Google Scholar
• Krieg C, Letourneau S, Pantaleo G, Boyman O. Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells. Proc Natl Acad Sci USA 2010;107:11906-11
   PubMed Web of Science ®Google Scholar
• Gillies SD, Lan Y, Hettmann T, A low-toxicity IL-2-based immunocytokine retains antitumor activity despite its high degree of IL-2 receptor selectivity. Clin Cancer Res 2011;17:3673-85
   PubMed Web of Science ®Google Scholar
• Gocheva V, Wang HW, Gadea BB, IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes Dev 2010;24:241-55
   PubMed Web of Science ®Google Scholar
• Chi X, Tai HH. Interleukin-4 up-regulates 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in human lung cancer cells. Exp Cell Res 2010;316:2251-9
   Google Scholar
• Ochoa CE, Mirabolfathinejad SG, Ruiz VA, Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis. Cancer Prev Res (Phila) 2011;4:51-64
   PubMed Web of Science ®Google Scholar
• Huang WL, Yeh HH, Lin CC, Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells. Mol Cancer 2010;9:309
   PubMed Web of Science ®Google Scholar
• Song L, Rawal B, Nemeth JA, Haura EB. JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling. Mol Cancer Ther 2011;10:481-94
   PubMed Web of Science ®Google Scholar
• Yao Z, Fenoglio S, Gao DC, TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proc Natl Acad Sci USA 2010;107:15535-40
   PubMed Web of Science ®Google Scholar
• Eikawa S, Ohue Y, Kitaoka K, Enrichment of Foxp3+ CD4 regulatory T cells in migrated T cells to IL-6- and IL-8-expressing tumors through predominant induction of CXCR1 by IL-6. J Immunol 2010;185:6734-40
   PubMed Web of Science ®Google Scholar
• Hsu YL, Hung JY, Ko YC, Phospholipase D signaling pathway is involved in lung cancer-derived IL-8 increased osteoclastogenesis. Carcinogenesis 2010;31:587-96
   Google Scholar
• Miotto D, Cascio NL, Stendardo M, CD8+ T cells expressing IL-10 are associated with a favourable prognosis in lung cancer. Lung Cancer 2010;69:355-60
   PubMed Web of Science ®Google Scholar
• Kuo PL, Hung JY, Huang SK, Lung cancer-derived galectin-1 mediates dendritic cell anergy through inhibitor of DNA binding 3/IL-10 signaling pathway. J Immunol 2011;186:1521-30
   PubMed Web of Science ®Google Scholar
• Reynolds JM, Angkasekwinai P, Dong C. IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev 2010;21:413-23
   PubMed Web of Science ®Google Scholar
• Kryczek I, Wei S, Szeliga W, Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 2009;114:357-9
   PubMed Web of Science ®Google Scholar
• Ye ZJ, Zhou Q, Gu YY, Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion. J Immunol 2010;185:6348-54
   PubMed Web of Science ®Google Scholar
• Chen X, Xie Q, Cheng X, Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells. Cancer Sci 2010;101:2384-90
   PubMed Web of Science ®Google Scholar
• Burger JA, Stewart DJ. CXCR4 chemokine receptor antagonists: perspectives in SCLC. Expert Opin Investig Drugs 2009;18:481-90
   PubMed Web of Science ®Google Scholar
• Pfeiffer M, Hartmann TN, Leick M, Alternative implication of CXCR4 in JAK2/STAT3 activation in small cell lung cancer. Br J Cancer 2009;100:1949-56
   Google Scholar
• Minamiya Y, Saito H, Takahashi N, Expression of the chemokine receptor CXCR4 correlates with a favorable prognosis in patients with adenocarcinoma of the lung. Lung Cancer 2010;68:466-71
   PubMed Web of Science ®Google Scholar
• Grivennikov SI, Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 2011;70(Suppl 1):i104-8
   PubMedGoogle Scholar
• Greqorc V, De Braud FG, De Pas TM, Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. Clin Cancer Res 2011;17:1964-72
   Google Scholar
• Probst BL, Liu L, Ramesh V, Smac mimetics increase cancer cell response to chemotherapeutics in a TNF-alpha-dependent manner. Cell Death Differ 2010;17:1645-54
   PubMed Web of Science ®Google Scholar
• Bai L, Xu S, Chen W, Blocking NF-kappaB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death. Apoptosis 2011;16:45-54
   PubMed Web of Science ®Google Scholar
• Weir BA, Woo MS, Getz G, Characterizing the cancer genome in lung adenocarcinoma. Nature 2007;450:893-8
   PubMed Web of Science ®Google Scholar
• Ogiwara H, Kohno T, Nakanishi H, Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer. Oncogene 2008;27:4788-97
   Google Scholar
• Rauch TA, Zhong X, Wu X, High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci USA 2008;105:252-7
   PubMed Web of Science ®Google Scholar
• Meylan E, Dooley AL, Feldser DM, Requirement for NF-kappaB signaling in a mouse model of lung adenocarcinoma. Nature 2009;462:104-7
   PubMed Web of Science ®Google Scholar
• Crescenzi E, Pacifico F, Lavorgna A, NF-kappaB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells. Oncogene 2011;30:2707-17
   PubMedGoogle Scholar
• Tauler J, Mulshine JL. Lung cancer and inflammation: interaction of chemokines and hnRNPs. Curr Opin Pharmacol 2009;9:384-8
   PubMed Web of Science ®Google Scholar
• Tauler J, Zudaire E, Liu H, HnRNP A2/B1 modulates epithelial-mesenchymal transition in lung cancer cell lines. Cancer Res 2010;70:7137-47
   PubMed Web of Science ®Google Scholar
• Cho WC. Recent progress in genetic variants associated with cancer and their implications in diagnostics development. Expert Rev Mol Diagn 2010;10:699-703
   PubMed Web of Science ®Google Scholar
• Landvik NE, Hart K, Skaug V, A specific interleukin-1B haplotype correlates with high levels of IL1B mRNA in the lung and increased risk of non-small cell lung cancer. Carcinogenesis 2009;30:1186-92
   PubMed Web of Science ®Google Scholar
• Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y. IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population. J Thorac Oncol 2010;5:299-304
   PubMed Web of Science ®Google Scholar
• Hildebrandt MA, Komaki R, Liao Z, Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. PLoS ONE 2010;5:e12402
   PubMed Web of Science ®Google Scholar
• Truong T, Sauter W, McKay JD, International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants. Carcinogenesis 2010;31:625-33
   PubMed Web of Science ®Google Scholar
• Adcock IM. HDAC inhibitors as anti-inflammatory agents. Br J Pharmacol 2007;150:829-31
   PubMed Web of Science ®Google Scholar
• Blanco D, Vicent S, Fraga MF, Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway. Neoplasia 2007;9:840-52
   PubMed Web of Science ®Google Scholar
• Williams AE, Perry MM, Moschos SA, Role of miRNA-146a in the regulation of the innate immune response and cancer. Biochem Soc Trans 2008;36:1211-15
   PubMed Web of Science ®Google Scholar
• Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 2009;139:693-706
   PubMed Web of Science ®Google Scholar
• Iliopoulos D, Jaeger SA, Hirsch HA, STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol Cell 2010;39:493-506
   PubMed Web of Science ®Google Scholar
• Tili E, Michaille JJ, Wernicke D, Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. Proc Natl Acad Sci USA 2011;108:4908-13
   PubMed Web of Science ®Google Scholar
• Cho WC. MicroRNAs as therapeutic targets for lung cancer. Expert Opin Ther Targets 2010;14:1005-8
   PubMed Web of Science ®Google Scholar
• Gibbons DL, Rizvi ZH, Kurie JM. The role of microRNAs in lung cancer development, progression, and metastasis. In: Cho WC. editor. MicroRNAs in cancer translational research. New York: Springer; 2011. p. 73-89
   Google Scholar
• Germano G, Allavena P, Mantovani A. Cytokines as a key component of cancer-related inflammation. Cytokine 2008;43:374-9
   PubMed Web of Science ®Google Scholar
• Pierce BL, Ballard-Barbash R, Bernstein L, Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients. J Clin Oncol 2009;27:3437-44
   PubMed Web of Science ®Google Scholar
• Sahni A, Simpson-Haidaris PJ, Sahni SK, Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2). J Thromb Haemost 2008;6:176-83
   PubMed Web of Science ®Google Scholar
• Cremona M, Calabro E, Randi G, Elevated levels of the acute-phase serum amyloid are associated with heightened lung cancer risk. Cancer 2010;116:1326-35
   Google Scholar
• Cho WC, Yip TT, Cheng WW, Au JS. Serum amyloid A is elevated in the serum of lung cancer patients with poor prognosis. Br J Cancer 2010;102:1731-5
   PubMed Web of Science ®Google Scholar
• O'Dowd C, McRae LA, McMillan DC, Elevated preoperative C-reactive protein predicts poor cancer specific survival in patients undergoing resection for non-small cell lung cancer. J Thorac Oncol 2010;5:988-92
   Google Scholar
• Minamiya Y, Miura M, Hinai Y, The CRP 1846T/T genotype is associated with a poor prognosis in patients with non-small cell lung cancer. Tumour Biol 2010;31:673-9
   Google Scholar
• Heikkila K, Harris R, Lowe G, Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes Control 2009;20:15-26
   PubMed Web of Science ®Google Scholar
• Koch A, Fohlin H, Sorenson S. Prognostic significance of C-reactive protein and smoking in patients with advanced non-small cell lung cancer treated with first-line palliative chemotherapy. J Thorac Oncol 2009;4:326-32
   PubMed Web of Science ®Google Scholar
• Saha S, Harrison SH, Chen JY. Dissecting the human plasma proteome and inflammatory response biomarkers. Proteomics 2009;9:470-84
   PubMedGoogle Scholar
• Lin Y, Bai L, Chen W, Xu S. The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy. Expert Opin Ther Targets 2010;14:45-55
   PubMed Web of Science ®Google Scholar
• Seike T, Fujita K, Yamakawa Y, Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis. Clin Exp Metastasis 2011;28:13-25
   Google Scholar
• Navin N, Hicks J. Future medical applications of single-cell sequencing in cancer. Genome Med 2011;3:31
   PubMed Web of Science ®Google Scholar
• Navin N, Kendall J, Troge J, Tumour evolution inferred by single-cell sequencing. Nature 2011;472:90-4
   PubMed Web of Science ®Google Scholar
• Garcia MG, Alaniz L, Lopes EC, Inhibition of NF-kappaB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines. Leuk Res 2005;29:1425-34
   PubMed Web of Science ®Google Scholar
• Ravaud A, Cerny T, Terret C, Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumors: an ECSG/EORTC study. Eur J Cancer 2005;41:702-7
   PubMed Web of Science ®Google Scholar
• Yang J, Amiri KI, Burke JR, BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways. Clin Cancer Res 2006;12:950-60
   PubMed Web of Science ®Google Scholar
• Choo MK, Sakurai H, Kim DH, Saiki I. A ginseng saponin metabolite suppresses tumor necrosis factor-a-promoted metastasis by suppressing nuclear factor-kappaB signaling in murine colon cancer cells. Oncol Rep 2008;19:595-600
   PubMed Web of Science ®Google Scholar
• Hideshima T, Chauhan D, Kiziltepe T, Biologic sequelae of IkappaB kinase (IKK) inhibition in multiple myeloma: therapeutic implications. Blood 2009;113:5228-36
   PubMed Web of Science ®Google Scholar
• Jeon KI, Xu X, Aizawa T, Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proc Natl Acad Sci USA 2010;107:9795-800
   PubMed Web of Science ®Google Scholar
• Pandey MK, Sung B, Kunnumakkara AB, Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res 2008;68:5370-9
   PubMed Web of Science ®Google Scholar
• Choi KC, Lee YH, Jung MG, Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells. Mol Cancer Res 2009;7:2011-21
   PubMed Web of Science ®Google Scholar
• Wang X, Ju W, Renouard J, 17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway. Cancer Res 2006;66:1089-95
   PubMed Web of Science ®Google Scholar
• Wang X, Chen W, Lin Y. Sensitization of TNF-induced cytotoxicity in lung cancer cells by concurrent suppression of the NF-kappaB and Akt pathways. Biochem Biophys Res Commun 2007;355:807-12
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74
   PubMed Web of Science ®Google Scholar
• Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011;331:1565-70
   PubMed Web of Science ®Google Scholar
• Zhu Z, Shen Z. Targeting the inflammatory pathways to enhance chemotherapy of cancer. Cancer Biol Ther 2011;12:3
   Google Scholar
• Flores-Santana W, Moody T, Chen W, Redox-modified non-steroidal anti-inflammatory drugs as potential anti-cancer agents with the SOD mimetic nitroxide. Br J Pharmacol 2011: [Epub ahead of print]
   Google Scholar