Clinical consequences of polypharmacy in elderly

Bibliography

• Merriam Webster Medical Dictionary. Available from: http://www.merriam-webster.com/medlineplus/polypharmacy [Accessed 2 May] [2013]
   Google Scholar
• Tjia J, Velten SJ, Parsons C, et al. Studies to reduce unnecessary medication use in frail older adults: a systematic review. Drugs Aging 2013;30:285-307
   PubMed Web of Science ®Google Scholar
• Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007;5:345-51
   PubMedGoogle Scholar
• Boyd CM, Darer J, Boult C, et al. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA 2005;294:716-24
   PubMed Web of Science ®Google Scholar
• Qato DM, Alexander GC, Conti R, et al. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA 2008;300:2867-78
   PubMed Web of Science ®Google Scholar
• Chrischilles EA, Foley DJ, Wallace RB, et al. Use of medications by persons 65 and over: data from the Established Populations for Epidemiologic Studies of the Elderly. J Gerontol Med Sci 1992;47:137-44
   Google Scholar
• Rossi MI, Young A, Maher R, et al. Polypharmacy and health beliefs in older outpatients. Am J Geriatr Pharmacother 2007;5:317-23
   PubMedGoogle Scholar
• Hajjar E, Hanlon JT, Sloane RJ, et al. Unnecessary drug use in frail older people at hospital discharge. J Am Geriatr Soc 2005;53:1518-23
   PubMed Web of Science ®Google Scholar
• Nobili A, Licata G, Salerno F, et al. Polypharmacy, length of hospital stay and inpatient mortality among elderly patients in internal medicine wards. The REPOSI study. Eur J Clin Pharmacol 2011;67:507-19
   PubMed Web of Science ®Google Scholar
• Dwyer L, Han B, Woodwell D, et al. Polypharmacy in nursing home residents in the United States: results of the 2004 National Nursing Home Survey. Am J Geriatr Pharmacother 2009;8:63-72
   Web of Science ®Google Scholar
• Bronskill S, Sudeep S, Gill MD, et al. Exploring variation in rates of polypharmacy across long term care homes. JAMDA 2012;309:e15-21
   Google Scholar
• Akazawa M, Imai H, Igarashi A, Tsutani K. Potentially inappropriate medication use in elderly Japanese patients. Am J Geriatr Pharmacother 2010;8:146-60
   PubMed Web of Science ®Google Scholar
• Hovstadius B, Petersson G. The impact of increasing polypharmacy on prescribed drug expenditure-a register-based study in Sweden 2005-2009. Health Policy 2013;109:166-74
   PubMed Web of Science ®Google Scholar
• Bourgeois FT, Shannon MW, Valim C, et al. Adverse drug events in the outpatient setting: an 11-year national analysis. Pharmacoepidemiol Drug Saf 2010;19:901-10
   PubMed Web of Science ®Google Scholar
• Hohl CM, Dankoff J, Colacone A, et al. Polypharmacy, adverse drug-related events, and potential adverse drug interactions in elderly patients presenting to an emergency department. Ann Emerg Med 2001;38:666-71
   PubMed Web of Science ®Google Scholar
• Nguyen JK, Fouts MM, Kotabe SE, Lo E. Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents. Am J Geriatr Pharmacother 2006;4:36-41
   PubMedGoogle Scholar
• Marcum ZA, Amuan ME, Hanlon JT, et al. Prevalence of unplanned hospitalizations caused by adverse drug reactions in older veterans. J Am Geriatric Soc 2012;60:34-41
   PubMed Web of Science ®Google Scholar
• Gurwitz JH, Field TS, Harrold LR, et al. Incidence and preventability of adverse drug events among older persons in the ambulatory setting. JAMA 2003;289:1107-16
   PubMed Web of Science ®Google Scholar
• Mallet L, Spinewine A, Huang A. The challenge of managing drug interactions in elderly people. Lancet 2007;370:185-91
   PubMed Web of Science ®Google Scholar
• Doan J, Zakrewski-Jakubiak H, Roy J, et al. Prevalence and risk of potential cytochrome p450-mediated drug-drug interactions in older hospitalized patients with polypharmacy. Ann Pharmacother 2013;47:324-32
   PubMed Web of Science ®Google Scholar
• Bjorkman IK, Fastbom J, Schmidt IK, et al. Drug-drug interactions in the elderly. Ann Pharmacother 2002;36:1165-71
   Google Scholar
• Juurlink DN, Mamdani M, Kopp A, et al. Drug-drug interactions among elderly patients hospitalized for drug toxicity. JAMA 2003;289:1652-8
   PubMed Web of Science ®Google Scholar
• Lindblad CI, Artz MB, Pieper CF, et al. Potential drug-disease interactions in frail, hospitalized elderly veterans. Ann Pharmacother 2005;39:412-17
   PubMed Web of Science ®Google Scholar
• Lindblad CI, Hanlon JT, Gross CR, et al. Clinically important drug- disease interactions and their prevalence in older adults. Clin Ther 2006;28:1133-43
   PubMed Web of Science ®Google Scholar
• Vik SA, Maxwell CJ, Hogan DB. Measurement, correlates, and health outcomes of medication adherence among seniors. Ann Pharmacother 2004;38:303-12
   PubMed Web of Science ®Google Scholar
• Lee VW, Pang KK, Hui KC, et al. Medication adherence: is it a hidden drug-related problem in hidden elderly? Geriatr Gerontol Int 2013; [Epub ahead of print]
   Web of Science ®Google Scholar
• Colley CA, Lucas LM. Polypharmacy: the cure becomes the disease. J Gen Int Med 1993;8:278-83
   PubMed Web of Science ®Google Scholar
• Salazar JA, Poon I, Nair M. Clinical consequences of polypharmacy in the elderly: expect the unexpected, think the unthinkable. Expert Opin Drug Saf 2007;6:695-704
   PubMed Web of Science ®Google Scholar
• Rollason V, Vogt N. Reduction of polypharmacy in the elderly: a systematic review of the role of the pharmacist. Drugs Aging 2003;20:817-32
   PubMed Web of Science ®Google Scholar
• Magaziner J, Cadigan DA, Fedder DO, Hebel JR. Medication use and functional decline among community-dwelling older women. J Aging Health 1989;1:470-84
   Google Scholar
• Crenstil V, Ricks MO, Xue QL, Fried LP. A pharmacoepidemiologic study of community-dwelling, disabled older women: factors associated with medication use. Am J Geriatr Pharmacother 2010;8:215-24
   PubMed Web of Science ®Google Scholar
• Jyrkka J, Enlund H, Lavikainen P, et al. Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol Drug Saf 2010;20:514-22
   Web of Science ®Google Scholar
• Rosso AL, Eaton CB, Wallace R, et al. Geriatric syndromes and incident disability in older women: results from the Women's Health Initiative Observational Study. J Am Geriatr Soc 2013;61(3):371-9
   PubMed Web of Science ®Google Scholar
• Stel VS, Smit JH, Plujim SM, Lips P. Consequences of falling in older men and women and risk factors for health service use and functional decline. Age Aging 2004;33:58-65
   PubMed Web of Science ®Google Scholar
• Martin NJ, Stones MJ, Young JE, et al. Development of delirium: a prospective cohort study in a community hospital. Int Psychogeriatr 2000;12:117-27
   PubMed Web of Science ®Google Scholar
• Fletcher PC, Berg K, Dalby DM, Hirdes JP. Risk factors for falling among community-based seniors. J Patient Saf 2009;5:61-6
   PubMedGoogle Scholar
• Kojima T, Akishita M, Nakamura T, et al. Association of polypharmacy with fall risk among geriatric outpatients. Geriatr Gerontol Int 2011;11:438-44
   PubMed Web of Science ®Google Scholar
• Tromp AM, Plujim SM, Smit JH, et al. Fall-risk screening test: a positive study of predictors for falls in community-dwelling elderly. J Clin Epidemiol 2001;54:837-44
   PubMed Web of Science ®Google Scholar
• Lee CY, Chen LK, Lo YK, et al. Urinary incontinence: an under-recognized risk factor for falls among elderly dementia patients. Neurourol Urodyn 2011;30:1286-90
   PubMed Web of Science ®Google Scholar
• Damian J, Pastor-Barriuso R, Valderrama-Gama E, de Pedro-Cuesta J. Factors associated with falls among older adults living in institutions. BMC Geriatr 2013;13:6
   PubMedGoogle Scholar
• Nuotio M, Jylha M, Luukkaala T, Tammela T. Health problems associated with lower urinary tract symptoms in older women. Scand J Prim Care 2005;23:209-14
   PubMed Web of Science ®Google Scholar
• Heuberger RA, Caudell K. Polypharmacy and nutritional status in older adults. Drugs Aging 2011;28:315-23
   PubMed Web of Science ®Google Scholar
• Prithviraj GK, Koroukian S, Margevicius S, et al. Patient characteristics associated with polypharmacy and inappropriate prescribing of medications among older adults with cancer. J Geriatr Oncol 2012;3:228-37
   PubMed Web of Science ®Google Scholar
• Bao Y, SHao H, Bishop TF, et al. Inappropriate medication in a national sample of US elderly patients receiving home health care. J Gen Intern Med 2012;27:304-10
   PubMed Web of Science ®Google Scholar
• Cannon KT, Choi MM, Zuniga MA. Potentially inappropriate medication use in patients receiving home health care: a retrospective data analysis. Am J Geriatr Pharmacother 2006;4:134-43
   PubMedGoogle Scholar
• Patterson SM, Hughes C, Kerse N, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev 2012;5:CD008165
   PubMed Web of Science ®Google Scholar
• Schmader KE, Hanlon JT, Pieper CF, et al. Effectiveness of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly. Am J Med 2004;116:394-401
   PubMed Web of Science ®Google Scholar
• Spinewine A, Swine C, Dhillon S, et al. Effect of a collaborative approach on the quality of prescribing for geriatric inpatients: a randomized, controlled trial. J Am Geriatr Soc 2007;55:658-65
   PubMed Web of Science ®Google Scholar
• Hanlon JT, Weinberger M, Samsa GP, et al. A randomized controlled trial of a clinical pharmacist intervention with elderly outpatients with polypharmacy. Am J Med 1996;100:428-3
   PubMed Web of Science ®Google Scholar
• Gallagher PF, O'Connor MN, O'Mahony D. Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START Criteria. Clin Pharmacol Ther 2011;89:845-54
   PubMed Web of Science ®Google Scholar
• Bregnhoj L, Thirstrup S, Kristensen MB, et al. Combined intervention programme reduces inappropriate prescribing in elderly patients exposed to polypharmacy in primary care. Eur J Clin Pharmacol 2009;65:199-207
   PubMed Web of Science ®Google Scholar
• Lipton HL, Bero LA, Bird JA, McPhee SJ. The impact of clinical pharmacists' consultations on physicians' geriatric drug prescribing. A randomized controlled trial. Med Care 1992;30:646-58
   PubMed Web of Science ®Google Scholar
• Owens NJ, Sherburne NJ, Silliman RA, Fretwell MD. The Senior Care Study : the optimal use of medications in acutely ill older patients. J Am Geriatr Soc 1990;38:1082-7
   PubMed Web of Science ®Google Scholar
• Krska J, Cromarty JA, Arris F, et al. Pharmacist-led medication review in patients over 65: a randomized, controlled trial in primary care. Age Ageing 2001;30:205-11
   PubMed Web of Science ®Google Scholar
• Hellström LM, Bondesson A, Höglund P, et al. Impact of the Lund Integrated Medicines Management (LIMM) model on medication appropriateness and drug-related hospital revisits. Eur J Clin Pharmacol 2011;67:741-52
   PubMed Web of Science ®Google Scholar
• Crotty M, Rowett D, Spurling L, et al. Does the addition of a pharmacist transition coordinator improve evidence-based medication management and health outcomes in older adults moving from the hospital to a long-term care facility? results of a randomized, controlled trial. Am J Geriatr Pharmacother 2004;2:257-64
   PubMedGoogle Scholar
• Pellegrino AN, Martin MT, Tilton JJ, et al. Medication therapy management services. Drugs 2009;69(4):393-406
   PubMed Web of Science ®Google Scholar