New delivery systems to improve the bioavailability of resveratrol

Bibliography

• de la Lastra CA, Villegas I. Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications. Biochem Soc Trans 2007;35(5):1156-60
   PubMed Web of Science ®Google Scholar
• Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J 2003;17(14):1975-85
   PubMed Web of Science ®Google Scholar
• Kristl J, Teskac K, Caddeo C, Improvements of cellular stress response on resveratrol in liposomes. Eur J Pharm Biopharm 2009;73(2):253-9
   PubMed Web of Science ®Google Scholar
• Gulcin I. Antioxidant properties of resveratrol: A structure–activity insight. Innovat Food Sci Emerg Tech 2010;11(1):210-18
   Web of Science ®Google Scholar
• Jensen J, Wertz C, O'Neill V. Preformulation stability of trans-resveratrol and trans-resveratrol glucoside (Piceid). J Agric Food Chem 2010;58(3):1685-90
   PubMed Web of Science ®Google Scholar
• Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006;5(6):493-506
   PubMed Web of Science ®Google Scholar
• Burkon A, Somoza V. Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - two novel resveratrol metabolites in human plasma. Mol Nutr Food Res 2008;52(5):549-57
   PubMed Web of Science ®Google Scholar
• Shi G, Rao L, Yu H, Stabilization and encapsulation of photosensitive resveratrol within yeast cell. Int J Pharm 2008;349(1-2):83-93
   PubMed Web of Science ®Google Scholar
• Juhasz B, Varga B, Gesztelyi R, Resveratrol: a multifunctional cytoprotective molecule. Curr Pharm Biotechnol 2010;11(8):810-18
   PubMed Web of Science ®Google Scholar
• Grill JD, Cummings JL. Current therapeutic targets for the treatment of Alzheimer's disease. Expert Rev Neurother 2010;10(5):711-28
   PubMed Web of Science ®Google Scholar
• Sun AY, Wang Q, Simonyi A, Resveratrol as a Therapeutic Agent for Neurodegenerative Diseases. Mol Neurobiol 2010;41(2-3):375-83
   PubMed Web of Science ®Google Scholar
• Gatouillat G, Balasse E, Joseph-Pietras D, Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J Cell Biochem 2010;110(4):893-902
   PubMed Web of Science ®Google Scholar
• Subramanian L, Youssef S, Bhattacharya S. Resveratrol: challenges in translation to the clinic - a critical discussion. Clin Cancer Res 2010;16(24):5942-8
   PubMed Web of Science ®Google Scholar
• Kroon PA, Iyer A, Chunduri P, The cardiovascular nutrapharmacology of resveratrol: pharmacokinetics, molecular mechanisms and therapeutic potential. Curr Med Chem 2010;17(23):2442-55
   PubMed Web of Science ®Google Scholar
• Tsunoda I, Rose JW, Rojas M, Treatment of an animal model for multiple sclerosis with resveratrol, a natural compound in red wine. J Neuroimmunol 2008;203(2):247
   Web of Science ®Google Scholar
• Cui X, Jin Y, Hofseth AB, Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prev Res (Phila Pa) 2010;3(4):549-59
   PubMed Web of Science ®Google Scholar
• Jha RK, Ma Q, Sha H, Protective effect of resveratrol in severe acute pancreatitis-induced brain injury. Pancreas 2009;38(8):947-53
   PubMed Web of Science ®Google Scholar
• Almeida L, Vaz-da-Silva M, Falcao A, Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Mol Nutr Food Res 2009;53(1):7-15
   PubMedGoogle Scholar
• Lu X, Ji C, Xu H, Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress. Int J Pharm 2009;37(1-2):89-96
   Google Scholar
• Caddeo C, Teskac K, Sinico C, Effect of resveratrol incorporated in liposomes on proliferation and UV-B protection of cells. Int J Pharm 2008;363(1-2):183-91
   PubMed Web of Science ®Google Scholar
• Lopez-Nicolas JM, Rodriguez-Bonilla P, Garcia-Caramona F. Complexation of Pinosylvin, an analogue of resveratrol with high antifungal and antimicrobial activity, by different types of cyclodextrins. J Agric Food Chem 2009;57(21):10175-80
   PubMed Web of Science ®Google Scholar
• Ros RZ. Resveratrol: marcador biologic i dietetic de consum de vi. Barcelona: 2008
   Google Scholar
• Henry C, Vitrac X, Decendit A, Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells. J Agric Food Chem 2005;53(3):798-803
   PubMed Web of Science ®Google Scholar
• Kuhnle G, Spencer JP, Chowrimootoo G, Resveratrol is absorbed in the small intestine as resveratrol glucuronide. Biochem Biophys Res Commun 2000;272(1):212-17
   PubMed Web of Science ®Google Scholar
• Walle T, Hsieh F, DeLegge MH, High absortion but very low bioavailability of oral resveratrol in humans. Drug Metab Dispos 2004;32(12):1377-82
   PubMed Web of Science ®Google Scholar
• Das S, Lin HS, Ho PC, The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol. Pharm Res 2008;25(11):2593-600
   PubMed Web of Science ®Google Scholar
• Kapetanovic IM, Muzzio M, Huang Z, Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol 20 Nov 2010; [Epub ahead of print]
   Web of Science ®Google Scholar
• Zhou M, Chen X, Zhong D. Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci 2007;854(1-2):219-23
   PubMed Web of Science ®Google Scholar
• Wenzel E, Somoza V. Metabolism and bioavailability of trans-resveratrol. Mol Nutr Food Res 2005;49(5):472-81
   PubMed Web of Science ®Google Scholar
• Miksits M, Maier-Salamon A, Aust S, Sulfation of resveratrol in human liver: Evidence of a major role for the sulfotransferases SULT1A1 and SULT1E1. Xenobiotica 2005;35(12):1101-19
   PubMed Web of Science ®Google Scholar
• Marier JF, Vachon P, Gritsas A, Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model. J Pharmacol Exp Ther 2002;302(1):369-73
   PubMed Web of Science ®Google Scholar
• Boocock DJ, Faust GE, Patel KR, Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. Cancer Epidemiol Biomarkers Prev 2007;16(6):1246-52
   PubMed Web of Science ®Google Scholar
• Ortuno J, Covas MI, Farre M, Matrix effects on the bioavailability of resveratrol in humans. Food Chem 2010;120(4):1123-30
   Web of Science ®Google Scholar
• Urpi-Sarda M, Jauregui O, Lamuela-Raventos RM, Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry. Anal Chem 2005;77(10):3149-55
   PubMed Web of Science ®Google Scholar
• Urpi-Sarda M, Zamora-Ros R, Lamuela-Raventos R, HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humans. Clin Chem 2007;53(2):292-9
   PubMed Web of Science ®Google Scholar
• Elliott PJ, Jirousek M. Sirtuins: novel targets for metabolic disease. Curr Opin Investig Drugs 2008;9(4):371-8
   PubMed Web of Science ®Google Scholar
• Vitaglione P, Sforza S, Galaverna G, Bioavailability of trans-resveratrol from red wine in humans. Mol Nutr Food Res 2005;49(5):495-504
   PubMed Web of Science ®Google Scholar
• Boocock DJ, Patel KR, Faust GE, Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2007;848(2):182-7
   PubMed Web of Science ®Google Scholar
• Wenzel E, Soldo T, Erbersdobler H, Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats. Mol Nutr Food Res 2005;49(5):482-94
   PubMed Web of Science ®Google Scholar
• Cottart CH, Nivet-Antoine V, Laguillier-Morizot C, Resveratrol bioavailability and toxicity in humans. Mol Nutr Food Res 2010;54(1):7-16
   PubMed Web of Science ®Google Scholar
• Orallo F. Comparative studies of the antioxidant effects of cis- and trans-resveratrol. Curr Med Chem 2006;13(1):87-98
   PubMed Web of Science ®Google Scholar
• Gescher AJ, Steward WP. Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum. Cancer Epidemiol Biomarkers Prev 2003;12(10):953-7
   PubMed Web of Science ®Google Scholar
• Athar M, Back JH, Tang X, Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol 2007;224(3):274-83
   PubMed Web of Science ®Google Scholar
• Juan ME, Wenzel U, Daniel H, Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells. J Agric Food Chem 2008;56(12):4813-18
   PubMed Web of Science ®Google Scholar
• Dudley J, Das S, Mukherjee S, Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J Nutr Biochem 2009;20(6):443-52
   PubMed Web of Science ®Google Scholar
• Jang MH, Piao XL, Kim HY, Resveratrol oligomers from Vitis amurensis attenuate beta-amyloid-induced oxidative stress in PC12 cells. Biol Pharm Bull 2007;30(6):1130-4
   PubMed Web of Science ®Google Scholar
• Sharma V, McNeill JH. To scale or not to scale: the principles of dose extrapolation. Br J Pharmacol 2009;157(6):907-21
   PubMed Web of Science ®Google Scholar
• Zamora-Ros R, Urpi-Sarda M, Lamuela-Raventos RM, Diagnostic performance of urinary resveratrol metabolites as a biomarker of moderate wine consumption. Clin Chem 2006;52(7):1373-80
   PubMed Web of Science ®Google Scholar
• Zamora-Ros R, Urpi-Sarda M, Lamuela-Raventos RM, Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: the PREDIMED study. Free Radic Biol Med 2009;46(12):1561
   PubMed Web of Science ®Google Scholar
• Suri S, Liu XH, Rayment S, Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery. Br J Pharmacol 2010;159(3):566-75
   PubMed Web of Science ®Google Scholar
• Tribolo S, Lodi F, Connor C, Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells. Atherosclerosis 2008;197(1):50-6
   PubMed Web of Science ®Google Scholar
• Shu XH, Li H, Sun Z, Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol 2010;79(10):1516-25
   PubMed Web of Science ®Google Scholar
• Miksits M, Wlcek K, Svoboda M, Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells. Planta Med 2009;75(11):1227-30
   PubMed Web of Science ®Google Scholar
• Wang LX, Heredia A, Song H, Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity. J Pharm Sci 2004;93(10):2448-57
   PubMed Web of Science ®Google Scholar
• Mikulski D, Gorniak R, Molski M. A theoretical study of the structure-radical scavenging activity of trans-resveratrol analogues and cis-resveratrol in gas phase and water environment. Eur J Med Chem 2010;45(3):1015-27
   PubMed Web of Science ®Google Scholar
• Orsini F, Verotta L, Lecchi M, Resveratrol derivatives and their role as potassium channels modulators. J Nat Prod 2004;67(3):421-6
   PubMed Web of Science ®Google Scholar
• Asensi M, Medina I, Ortega A, Inhibition of cancer growth by resveratrol is related to its low bioavailability. Free Radic Biol Med 2002;33(3):387-98
   PubMed Web of Science ®Google Scholar
• Regev-Shoshani G, Shoseyov O, Bilkis I, Glycosylation of resveratrol protects it from enzymatic oxidation. Biochem J 2003;374(Pt 1):157-63
   PubMedGoogle Scholar
• Pervaiz S, Holme AL. Resveratrol: its biologic targets and functional activity. Antioxid Redox Signal 2009;11(11):2851-97
   PubMed Web of Science ®Google Scholar
• Hu M. Commentary: bioavailability of flavonoids and polyphenols: call to arms. Mol Pharm 2007;4(6):803-6
   PubMed Web of Science ®Google Scholar
• Fuchs S, Kutscher M, Hertel T, Transglutaminase: new insights into gelatin nanoparticle cross-linking. J Microencapsul 2010;27(8):747-54
   PubMed Web of Science ®Google Scholar
• Peter M, Binulal NS, Nair SV, Novel biodegradable chitosan–gelatin/nano-bioactive glass ceramic composite scaffolds for alveolar bone tissue engineering. Chem Eng J 2010;158(2):353-61
   Web of Science ®Google Scholar
• Atanackovic M, Posa M, Heinle H, Solubilization of resveratrol in micellar solutions of different bile acids. Colloids Surf B Biointerfaces 2009;72(1):148-54
   PubMed Web of Science ®Google Scholar
• Pinto Reis C, Neufeld RJ, Ribeiro AJ, Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine 2006;2(1):8-21
   PubMed Web of Science ®Google Scholar
• Borgogna M, Bellich B, Zorzin L, Food microencapsulation of bioactive compounds: Rheological and thermal characterisation of non-conventional gelling system. Food Chem 2010;122(2):416-23
   Web of Science ®Google Scholar
• Chen C, inventor. Casein-resveratrol complex used as supplement for food, feed, beverage, pharmaceutically active agent, or as component of cosmetic preparations, for improvement of physical or mental state of mammal comprises resveratrol and casein. WO2008017415-A1; 2008 04-22-2010
   Google Scholar
• Nam J-B, Ryu J-H, Kim J-W, Stabilization of resveratrol immobilized in monodisperse cyano-functionalized porous polymeric microspheres. Polymer (Guildf) 2005;46(21):8956-63
   Web of Science ®Google Scholar
• Das S, Ng KY. Colon-specific delivery of resveratrol: Optimization of multi-particulate calcium-pectinate carrier. Int J Pharm 2009;385(1-2):20-8
   PubMedGoogle Scholar
• Peng H, Xiong H, Li J, Vanillin cross-linked chitosan microspheres for controlled release of resveratrol. Food Chem 2010;121(1):23-8
   Web of Science ®Google Scholar
• Lu Z, Cheng B, Hu Y, Complexation of resveratrol with cyclodextrins: Solubility and antioxidant activity. Food Chem 2009;113(1):17-20
   Web of Science ®Google Scholar
• Shao J, Li X, Lu X, Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels. Colloids Surf B Biointerfaces 2009;72(1):40-7
   PubMed Web of Science ®Google Scholar
• Teskac K, Kristl J. The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol. Int J Pharm 2010;390(1):61-9
   PubMed Web of Science ®Google Scholar
• Fang JY, Hung CF, Liao MH, A study of the formulation design of acoustically active lipospheres as carriers for drug delivery. Eur J Pharm Biopharm 2007;67(1):67-75
   PubMed Web of Science ®Google Scholar
• Kabanov AV, Gendelman HE. Nanomedicine in the diagnosis and therapy of neurodegenerative disorders. Prog Polym Sci 2007;32(8-9):1054-82
   PubMed Web of Science ®Google Scholar
• Han DW, Lee JJ, Jung DY, Development of epigallocatechin gallate-eluting polymeric stent and its physicochemical, biomechanical and biological evaluations. Biomed Mater 2009;4(4):044104 Available online at: http://iopscience.iop.org/1748-605X/4/4/044104 [Last accessed 18 May]
   Web of Science ®Google Scholar
• Italia JL, Datta P, Ankola DD, Nanoparticles enhance per oral bioavailability of poorly available molecules: epigallocatechin gallate nanoparticles ameliorates cyclosporine induced nephrotoxicity in rats at three times lower dose than oral solution. J Biomed Nanotechnol 2008;4(3):304-12
   Web of Science ®Google Scholar
• Sahu A, Bora U, Kasoju N, Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells. Acta Biomater 2008;4(6):1752-61
   PubMed Web of Science ®Google Scholar
• Thangapazham RL, Puri A, Tele S, Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells. Int J Oncol 2008;32(5):1119-23
   PubMed Web of Science ®Google Scholar
• Das RK, Kasoju N, Bora U. Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells. Nanomedicine 2010;6(1):153-60
   PubMed Web of Science ®Google Scholar
• Merrell JG, McLaughlin SW, Tie L, Curcumin-loaded poly(epsilon-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties. Clin Exp Pharmacol Physiol 2009;36(12):1149-56
   PubMed Web of Science ®Google Scholar
• Li J, Wang Y, Yang C, Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1. Mol Pharmacol 2009;76(1):81-90
   PubMed Web of Science ®Google Scholar
• Hu Y, Jiang X, Ding Y, Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)-poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles. Biomaterials 2003;24(13):2395-404
   PubMed Web of Science ®Google Scholar
• Zhang L, Hu Y, Jiang X, Camptothecin derivative-loaded poly(caprolactone-co-lactide)-b-PEG-b-poly(caprolactone-co-lactide) nanoparticles and their biodistribution in mice. J Control Release 2004;96(1):135-48
   PubMed Web of Science ®Google Scholar
• Narayanan NK, Nargi D, Randolph C, Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer 2009;125(1):1-8
   PubMed Web of Science ®Google Scholar
• Kennedy DO, Wightman EL, Reay JL, Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. Am J for Clin Nutr 2010;91(6):1590-7
   PubMed Web of Science ®Google Scholar
• Liao PC, Ng LT, Lin LT, Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells. J Med Food 2010;13(6):1415-23
   PubMed Web of Science ®Google Scholar
• Quincozes-Santos A, Gottfried C. Resveratrol modulates astroglial functions: neuroprotective hypothesis. Ann NY Acad Sci 2011;1215(1):72-8
   PubMedGoogle Scholar
• Zhang H, Zhang J, Ungvari Z. Resveratrol Improves endothelial function: role of TNF{alpha} and vascular oxidative stress. Arterioscler Thromb Vasc Biol 2009;29(8):1164-71
   PubMed Web of Science ®Google Scholar
• Csiszar A, Labinskyy N, Pinto JT, Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol 2009;297(1):H13-20
   PubMed Web of Science ®Google Scholar
• Ungvari Z, Bagi Z, Feher A, Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 2010;299(1):H18-24
   PubMed Web of Science ®Google Scholar
• Meng X, Maliakal P, Lu H, Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice. J Agric Food Chem 2004;52(4):935-42
   PubMed Web of Science ®Google Scholar
• Soleas GJ, Yan J, Goldberg DM. Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection. J Chromatogr B Biomed Sci Appl 2001;757(1):161-72
   PubMedGoogle Scholar
• Soleas GJ, Yan J, Goldberg DM. Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection. Methods Enzymol 2001;335:130-45
   PubMed Web of Science ®Google Scholar
• Goldberg DM, Yan J, Soleas GJ. Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Clin Biochem 2003;36(1):79-87
   PubMed Web of Science ®Google Scholar
• la Porte C, Voduc N, Zhang G, Steady-state pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Clinic Pharmacokinet 2010;49(7):449-54
   PubMed Web of Science ®Google Scholar
• Ohguchi K, Tanaka T, Ito T, Inhibitory effects of resveratrol derivatives from dipterocarpaceae plants on tyrosinase activity. Biosci Biotechnol Biochem 2003;67(7):1587-9
   PubMed Web of Science ®Google Scholar
• Arigony Souto A. Resveratrol/cyclodextrin compound-containing water soluble complex e.g. for treating inflammation is prepared by adding cyclodextrin, organic solvent and resveratrol compound, heating, cooling and separating crystal. Eurofarma Lab Ltda; Uniao Brasileira Educacao E Assistencia Mantenedora Da Pucrs; Uniao Brasileira Educacao E Assistenci. 2009
   Google Scholar
• Altiok D, Altiok E, Bayraktar O, Stability of trans-Resveratrol Incorporated in Chitosan Microspheres. 2009 14th National Biomedical Engineering Meeting; Biyomut; 2009. p. 360-3
   Google Scholar