Analysis of factors influencing gastric emptying of pellets in a fed state

Bibliography

• Wilding IR, Coupe AJ, Davis SS. The role of gamma-scintigraphy in oral drug delivery. Adv Drug Delivery Rev 2001;46:103–24
   PubMed Web of Science ®Google Scholar
• Goodman K, Hodges LA, Band J, et al. Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy. Eur J Pharm Biopharm 2010;74:84–92
   PubMed Web of Science ®Google Scholar
• Weitschies W, Blume H, Mönnikes H. Magnetic marker monitoring: high resolution real-time tracking of oral solid dosage forms in the gastrointestinal tract. Eur J Pharm Biopharm 2010;74:93–101
   PubMed Web of Science ®Google Scholar
• Locatelli I, Mrhar A, Bogataj M. Gastric emptying of pellets under fasting conditions: a mathematical model. Pharm Res 2009;26:1607–17
   PubMed Web of Science ®Google Scholar
• Locatelli I, Nagelj Kovačič N, Mrhar A, Bogataj M. Gastric emptying of non-disintegrating solid drug delivery systems in a fasted state: relevance to drug dissolution. Expert Opin Drug Del 2010;7:967–76
   PubMed Web of Science ®Google Scholar
• Newton JM. Gastric emptying of multi-particulate dosage forms. Int J Pharm 2010;395:2–8
   PubMedGoogle Scholar
• FDA Guidance for Industry, Food-Effect Bioavailability and Fed Bioequivalence Studies. U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER). 2002. Available from: http://www.fda.gov/downloads/regulatoryinformation/guidances/ucm126833.pdf [Last accessed 5 March 2014]
   Google Scholar
• EMA Guideline on the Investigation of Bioequivalence European Medicines Agency. 2010. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2010/01/WC500070039.pdf [Last accessed 5 March 2014]
   Google Scholar
• Meyer JH, Elashoff J, Porter-Fink V, et al. human postprandial gastric emptying of 1-3-millimeter spheres. Gastroenterology 1988;94:1315–25
   PubMed Web of Science ®Google Scholar
• Yuen KH, Deshmukh AA, Newton JM, et al. Gastrointestinal transit and absorption of theophylline from a multi-particulate controlled release formulation. Int J Pharm 1993;97:61–77
   Web of Science ®Google Scholar
• Wilding IR, Sparrow RA, Davis SS, Horton RJ. The role of gastric emptying in the absorption and metabolism of nifedipine given in a modified release pellet formulation. Int J Pharm 1992;84:59–67
   Web of Science ®Google Scholar
• Podczeck F, Newton JM, Yuen KH. The description of the gastrointestinal transit of pellets assessed by gamma scintigraphy using statistical moments. Pharm Res 1995;12:376–9
   PubMed Web of Science ®Google Scholar
• Davis SS, Khosla R, Wilson CG, Washington N. gastrointestinal transit of a controlled-release pellet formulation of tiaprofenic acid and the effect of food. Int J Pharm 1987;35:253–8
   Web of Science ®Google Scholar
• Wilding IR, Davis SS, Sparrow RA, et al. The effect of food on the in vivo behaviour of a novel sustained release formulation of tiaprofenic acid. Int J Pharm 1992;83:155–61
   Google Scholar
• Coupe AJ, Davis SS, Evans DF, Wilding IR. Do pellet formulations empty from stomach with food? Int J Pharm 1993;92:167–75
   Web of Science ®Google Scholar
• Davis SS, Hardy JG, Taylor MJ, et al. A comparative study of the gastrointestinal transit of a pellet and tablet formulation. Int J Pharm 1984;21:167–77
   Web of Science ®Google Scholar
• Devereux JE, Newton JM, Short MB. The influence of density on the gastrointestinal transit of pellets. J Pharm Pharmacol 1990;42:500–1
   PubMed Web of Science ®Google Scholar
• Davis SS, Hardy JG, Fara JW. Transit of pharmaceutical dosage forms through the small intestine. Gut 1986;27:886–92
   PubMed Web of Science ®Google Scholar
• Horikawa Y. Gastric emptying of three different size of indigestible radiopaque markers in healthy subjects. J Smooth Muscle Res 1998;34:83–8
   PubMedGoogle Scholar
• Stotzer PO, Abrahamsson H. Human postprandial gastric emptying of indigestible solids can occur unrelated to antral phase III. Neurogastroenterol Motil 2000;12:415–19
   PubMed Web of Science ®Google Scholar
• Feely LC, Davis SS. Correlation of phenylpropanolamine bioavailability with gastrointestinal transit by scintigraphic monitoring of 111in-labeled hydroxypropylmethylcellulose matrices. Pharm Res 1989;6:274–8
   PubMed Web of Science ®Google Scholar
• Kedzierewicz F, Thouvenot P, Lemut J, et al. Evaluation of peroral silicone dosage forms in humans by gamma-scintigraphy. J Control Release 1999;58:195–205
   PubMed Web of Science ®Google Scholar
• Digenis GA, Sandefer EP, Parr AF, et al. Gastrointestinal behavior of orally administered radiolabeled erythromycin pellets in man as determined by gamma scintigraphy. J Clin Pharmacol 1990;30:621–31
   PubMed Web of Science ®Google Scholar
• Nielsen OH, Gjørup T, Christensen FN. Gastric emptying rate and small bowel transit time in patients with irritable bowel syndrome determined with 99mtc-labeled pellets and scintigraphy. Digest Dis Sci 1986;31:1287–91
   PubMed Web of Science ®Google Scholar
• O’Reilly S, Wilson CG, Hardy JG. The influence of food on the gastric emptying of multi-particulate dosage forms. Int J Pharm 1987;34:213–16
   Web of Science ®Google Scholar
• Kong F, Singh RP. Disintegration of solid foods in human stomach. J Food Sci 2008;73:67–80
   PubMed Web of Science ®Google Scholar
• Bennink R, Peeters M, Van den Maegdenbergh V, et al. Comparison of total and compartmental gastric emptying and antral motility between healthy men and women. Eur J Nucl Med 1998;25:1293–9
   PubMedGoogle Scholar
• Wilding IR, Hardy JG, Maccari M, et al. Scintigraphic and pharmacokinetic assessment of a multiparticulate sustained release formulation of diltiazem. Int J Pharm 1991;76:133–43
   Web of Science ®Google Scholar
• Hunter E, Fell JT, Sharma H. The gastric emptying of pellets contained in hard gelatin capsules. Drug Dev Ind Pharm 1982;8:751–7
   Web of Science ®Google Scholar
• Hardy JG, Lamont GL, Evans DF, et al. Evaluation of an enteric-coated naproxen pellet formulation. Aliment Pharmacol Ther 1991;5:69–75
   PubMed Web of Science ®Google Scholar
• Sato Y, Kawashima Y, Takeuchi H, et al. Pharmacoscintigraphic evaluation of riboflavin-containing microballoons for a floating controlled drug delivery system in healthy humans. J Control Release 2004;98:75–85
   PubMed Web of Science ®Google Scholar
• Coupe AJ, Davis SS, Wilding IR. Variation in gastrointestinal transit of pharmaceutical dosage forms in healthy subjects. Pharm Res 1991;3:360–4
   Google Scholar
• Davis SS, Hardy JG, Taylor MJ, et al. the effect of food on the gastrointestinal transit of pellets and an osmotic device (osmet). Int J Pharm 1984;21:331–40
   Web of Science ®Google Scholar
• Fischer W, Boertz A, Davis SS, et al. Investigation of the gastrointestinal transit and in vivo drug release of isosorbide-5-nitrate pellets. Pharm Res 1987;4:480–5
   PubMed Web of Science ®Google Scholar
• Kenyon CJ, Hooper G, Tierney D, et al. The effect of food on the gastrointestinal transit and systemic absorption of naproxen from a novel sustained release formulation. J Control Release 1995;34:31–6
   Web of Science ®Google Scholar
• Souci WS, Fachmann W, Kraut H. Food composition and nutrition tables. 7th edition. MedPharm Scientific Publishers, Taylor & Francis; Stuttgart: 2008
   Google Scholar
• Bürmen B, Locatelli I, Bürmen A, et al. Mathematical modeling of individual gastric emptying of pellets in the fed state. J Drug Del Sci Tech 2014;24(4):418–24
   Web of Science ®Google Scholar
• Draper NR, Smith H. Applied regression analysis. Wiley; New York: 1998
   Google Scholar
• Blackwell JN, Holt S, Heading RC. Effect of nifedipine on oesophageal motility and gastric emptying. Digestion 1981;21:50–6
   PubMed Web of Science ®Google Scholar
• Traube M, Lange RC, McAllister RG, McCallum RW. Effect of nifedipine on gastric emptying in normal subjects. Digest Dis Sci 1985;30:710–12
   PubMed Web of Science ®Google Scholar
• Santander R, Mena I, Gramisu M, Valenzuela JE. Effect of nifedipine on gastric emptying and gastrointestinal motility in man. Digest Dis Sci 1988;33:535–53
   PubMed Web of Science ®Google Scholar