Pharmacokinetics of triamcinolone acetonide for the treatment of macular edema

Bibliography

• Johnson MW. Etiology and treatment of macular edema. Am J Ophthalmol 2009;147(10):11-21; e11
   PubMedGoogle Scholar
• Scholl S, Kirchhof J, Augustin AJ. Pathophysiology of macular edema. Ophthalmologica 2010;224(Suppl 1):8-15
   PubMedGoogle Scholar
• Jermak CM, Dellacroce JT, Heffez J, Peyman GA. Triamcinolone acetonide in ocular therapeutics. Surv Ophthalmol 2007;52(5):503-22
   PubMed Web of Science ®Google Scholar
• Peyman GA, Herbst R. Bacterial endophthalmitis. Treatment with intraocular injection of gentamicin and dexamethasone. Arch Ophthalmol 1974;91(5):416-18
   PubMed Web of Science ®Google Scholar
• Diabetic Retinopathy Clinical Research Network. A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema. Ophthalmology 2008;115(9):1447-9; 1449 e1441-1410
   PubMed Web of Science ®Google Scholar
• Silva PS, Sun JK, Aiello LP. Role of steroids in the management of diabetic macular edema and proliferative diabetic retinopathy. Semin Ophthalmol 2009;24(2):93-9
   PubMed Web of Science ®Google Scholar
• Unoki N, Nishijima K, Kita M, Randomised controlled trial of posterior sub-Tenon triamcinolone as adjunct to panretinal photocoagulation for treatment of diabetic retinopathy. Br J Ophthalmol 2009;93(6):765-70
   PubMed Web of Science ®Google Scholar
• Yilmaz T, Weaver CD, Gallagher MJ, Intravitreal triamcinolone acetonide injection for treatment of refractory diabetic macular edema: a systematic review. Ophthalmology 2009;116(5):902-11; quiz 912-903
   PubMed Web of Science ®Google Scholar
• Kuo CH, McCluskey P, Gillies M. Pharmacotherapeutic efficacy of preservative-free intravitreal triamcinolone acetonide. Expert Opin Pharmacother 2010;11(1):155-66
   PubMed Web of Science ®Google Scholar
• Robinson KA, Dickersin K. Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed. Int J Epidemiol 2002;31(1):150-3
   PubMed Web of Science ®Google Scholar
• Spitzer MS, Kaczmarek RT, Yoeruek E, The distribution, release kinetics, and biocompatibility of triamcinolone injected and dispersed in silicone oil. Invest Ophthalmol Vis Sci 2009;50(5):2337-43
   PubMed Web of Science ®Google Scholar
• Tao Y, Jonas JB. Intravitreal triamcinolone. Ophthalmologica 2011;225(1):1-20
   PubMed Web of Science ®Google Scholar
• Gopal L, Sharma T. Use of intravitreal injection of triamcinolone acetonide in the treatment of age-related macular degeneration. Indian J Ophthalmol 2007;55(6):431-5
   PubMedGoogle Scholar
• Zimmerman TJ, Kooner K, Sharir M, Fechtner RD. Textbook of ocular pharmacology. Lippincott-Raven; Philadelphia: 1997
   Google Scholar
• Argenti D, Jensen BK, Hensel R, A mass balance study to evaluate the biotransformation and excretion of [14C]-triamcinolone acetonide following oral administration. J Clin Pharmacol 2000;40(7):770-80
   PubMed Web of Science ®Google Scholar
• Edelman JL, Lutz D, Castro MR. Corticosteroids inhibit VEGF-induced vascular leakage in a rabbit model of blood-retinal and blood-aqueous barrier breakdown. Exp Eye Res 2005;80(2):249-58
   PubMed Web of Science ®Google Scholar
• Guex-Crosier Y. Non-steroidal anti-inflammatory drugs and ocular inflammation. Klin Monatsbl Augenheilkd 2001;218(5):305-8
   PubMedGoogle Scholar
• Cervantes Castaneda RA, Giuliari GP, Intravitreal bevacizumab in refractory uveitic macular edema: one-year follow-up. Eur J Ophthalmol 2009;19(4):622-9
   PubMed Web of Science ®Google Scholar
• Greenberg PB, Martidis A, Rogers AH, Intravitreal triamcinolone acetonide for macular oedema due to central retinal vein occlusion. Br J Ophthalmol 2002;86(2):247-8
   PubMed Web of Science ®Google Scholar
• Kok H, Lau C, Maycock N, Outcome of intravitreal triamcinolone in uveitis. Ophthalmology 2005;112(11):1916; e1911-17
   PubMed Web of Science ®Google Scholar
• Scorolli L, Morara M, Meduri A, Treatment of cystoid macular edema in retinitis pigmentosa with intravitreal triamcinolone. Arch Ophthalmol 2007;125(6):759-64
   PubMed Web of Science ®Google Scholar
• Sutter FK, Gillies MC. Intravitreal triamcinolone for radiation-induced macular edema. Arch Ophthalmol 2003;121(10):1491-3
   PubMed Web of Science ®Google Scholar
• Wright PL, Wilkinson CP, Balyeat HD, Angiographic cystoid macular edema after posterior chamber lens implantation. Arch Ophthalmol 1988;106(6):740-4
   PubMed Web of Science ®Google Scholar
• Yilmaz T, Cordero-Coma M, Gallagher MJ, Teasley LA. Systematic review of intravitreal bevacizumab injection for treatment of primary diabetic macular oedema. Acta Ophthalmol 20 July 2010 . [Epub ahead of print]
   Google Scholar
• Yilmaz T, Cordero-Coma M, Lavaque AJ, Triamcinolone and intraocular sustained-release delivery systems in diabetic retinopathy. Curr Pharm Biotechnol 2011;12(3):337-46
   PubMed Web of Science ®Google Scholar
• Aiello LP, Avery RL, Arrigg PG, Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994;331(22):1480-7
   PubMed Web of Science ®Google Scholar
• Claesson-Welsh L. Signal transduction by vascular endothelial growth factor receptors. Biochem Soc Trans 2003;31(Pt 1):20-4
   PubMedGoogle Scholar
• Ishida S, Usui T, Yamashiro K, VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med 2003;198(3):483-9
   PubMed Web of Science ®Google Scholar
• Penfold PL, Wen L, Madigan MC, Triamcinolone acetonide modulates permeability and intercellular adhesion molecule-1 (ICAM-1) expression of the ECV304 cell line: implications for macular degeneration. Clin Exp Immunol 2000;121(3):458-65
   PubMed Web of Science ®Google Scholar
• Cekic O, Bardak Y, Tig SU, Hemodynamic response to intravitreal triamcinolone in eyes with macular edema: intravitreal triamcinolone and ocular blood flow. Int Ophthalmol 2007;27(5):313-19
   PubMedGoogle Scholar
• Mawatari Y, Koga T, Inumaru J, The effect of subtenon triamcinolone acetonide injection for diabetic macular edema on retinal and choroidal circulation. Am J Ophthalmol 2005;140(5):948-9
   PubMed Web of Science ®Google Scholar
• Vinten M, Larsen M, Lund-Andersen H, Short-term effects of intravitreal triamcinolone on retinal vascular leakage and trunk vessel diameters in diabetic macular oedema. Acta Ophthalmol Scand 2007;85(1):21-6
   PubMedGoogle Scholar
• Wickremasinghe SS, Rogers SL, Gillies MC, Retinal vascular caliber changes after intravitreal triamcinolone treatment for diabetic macular edema. Invest Ophthalmol Vis Sci 2008;49(11):4707-11
   PubMed Web of Science ®Google Scholar
• Cekic O, Bardak Y, Tig US, Quantitative evaluation of reduction of plaque-like hard exudates in diabetic macular edema after intravitreal triamcinolone injection. Int Ophthalmol 2008;28(2):95-9
   PubMedGoogle Scholar
• Avci R, Kaderli B. Intravitreal triamcinolone injection for chronic diabetic macular oedema with severe hard exudates. Graefes Arch Clin Exp Ophthalmol 2006;244(1):28-35
   PubMed Web of Science ®Google Scholar
• Beer PM, Bakri SJ, Singh RJ, Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 2003;110(4):681-6
   PubMed Web of Science ®Google Scholar
• Jonas JB. Intraocular availability of triamcinolone acetonide after intravitreal injection. Am J Ophthalmol 2004;137(3):560-2
   PubMed Web of Science ®Google Scholar
• Jonas JB. Concentration of intravitreally injected triamcinolone acetonide in aqueous humour. Br J Ophthalmol 2002;86(9):1066
   PubMed Web of Science ®Google Scholar
• Mason JO III, Somaiya MD, Singh RJ. Intravitreal concentration and clearance of triamcinolone acetonide in nonvitrectomized human eyes. Retina 2004;24(6):900-4
   PubMed Web of Science ®Google Scholar
• Audren F, Tod M, Massin P, Pharmacokinetic-pharmacodynamic modeling of the effect of triamcinolone acetonide on central macular thickness in patients with diabetic macular edema. Invest Ophthalmol Vis Sci 2004;45(10):3435-41
   PubMed Web of Science ®Google Scholar
• Degenring RF, Jonas JB. Serum levels of triamcinolone acetonide after intravitreal injection. Am J Ophthalmol 2004;137(6):1142-3
   PubMed Web of Science ®Google Scholar
• Riviere JE. Interspecies extrapolations. In: Ames IA. editor. Comparative pharmacokinetics: principles, techniques, and applications. Iowa State Press; Ames, Iowa: 1999. p. 296-307
   Google Scholar
• Nan K, Sun S, Li Y, Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-Tenon injection. Br J Ophthalmol 2010;94(5):654-8
   PubMed Web of Science ®Google Scholar
• Chin HS, Park TS, Moon YS, Oh JH. Difference in clearance of intravitreal triamcinolone acetonide between vitrectomized and nonvitrectomized eyes. Retina 2005;25(5):556-60
   PubMed Web of Science ®Google Scholar
• Schindler RH, Chandler D, Thresher R, Machemer R. The clearance of intravitreal triamcinolone acetonide. Am J Ophthalmol 1982;93(4):415-17
   PubMed Web of Science ®Google Scholar
• Scholes GN, O'Brien WJ, Abrams GW, Kubicek MF. Clearance of triamcinolone from vitreous. Arch Ophthalmol 1985;103(10):1567-9
   PubMed Web of Science ®Google Scholar
• Cheng L, Banker AS, Martin M, Triamcinolone acetonide concentration of aqueous humor after decanted 20-mg intravitreal injection. Ophthalmology 2009;116(7):1356-9
   PubMed Web of Science ®Google Scholar
• Kivilcim M, Peyman GA, El Retinal toxicity of triamcinolone acetonide in silicone-filled eyes. Ophthalmic Surg Lasers 2000;31(6):474-8
   PubMedGoogle Scholar
• McCuen BW II, Bessler M, Tano Y, The lack of toxicity of intravitreally administered triamcinolone acetonide. Am J Ophthalmol 1981;91(6):785-8
   PubMed Web of Science ®Google Scholar
• Vedantham V, Kolluru C, Ramasamy K. Persistent depot of triamcinolone acetonide after a single intravitreal injection. Indian J Ophthalmol 2005;53(1):65-6
   PubMedGoogle Scholar
• Francis BA, Chang EL, Haik BG. Particle size and drug interactions of injectable corticosteroids used in ophthalmic practice. Ophthalmology 1996;103(11):1884-8
   PubMed Web of Science ®Google Scholar
• Sanislo SR, Moshfeghi AA, Nugent AK, Triamcinolone acetonide preparations: impact of crystal size upon in vitro behavior. In: Paper Presented at: Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, Florida 2009
   Google Scholar
• Hsu J. Drug delivery methods for posterior segment disease. Curr Opin Ophthalmol 2007;18(3):235-9
   PubMed Web of Science ®Google Scholar
• Inoue M, Takeda K, Morita K, Vitreous concentrations of triamcinolone acetonide in human eyes after intravitreal or subtenon injection. Am J Ophthalmol 2004;138(6):1046-8
   PubMed Web of Science ®Google Scholar
• Lee SJ, Kim ES, Geroski DH, Pharmacokinetics of intraocular drug delivery of Oregon green 488-labeled triamcinolone by subtenon injection using ocular fluorophotometry in rabbit eyes. Invest Ophthalmol Vis Sci 2008;49(10):4506-14
   PubMed Web of Science ®Google Scholar
• Robinson MR, Lee SS, Kim H, A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide. Exp Eye Res 2006;82(3):479-87
   PubMed Web of Science ®Google Scholar
• Silva PS, Singh RJ, Bakri SJ, Vitreous concentration of triamcinolone acetonide after a single transseptal depot injection. Ocul Immunol Inflamm 2009;17(3):216-20
   PubMed Web of Science ®Google Scholar
• Hernaez-Ortega MC, Soto-Pedre E. A simple and rapid method for purification of triamcinolone acetonide suspension for intravitreal injection. Ophthalmic Surg Lasers Imaging 2004;35(4):350-1
   PubMed Web of Science ®Google Scholar
• Oishi M, Maeda S, Nakamura A, Examination of purification methods and development of intravitreal injection of triamcinolone acetonide. Jpn J Ophthalmol 2005;49(5):384-7
   PubMed Web of Science ®Google Scholar
• Korodi T, Lachmann B, Kopelent-Frank H. Evaluation of different preparation methods for a preservative free triamcinolone acetonide preparation for intravitreal administration: a validated stability indicating HPLC-method. Pharmazie 2010;65(12):860-6
   PubMed Web of Science ®Google Scholar
• Macky TA, Helmy D, El Shazly N. Retinal toxicity of triamcinolone's vehicle (benzyl alcohol): an electrophysiologic and electron microscopic study. Graefes Arch Clin Exp Ophthalmol 2007;245(6):817-24
   PubMed Web of Science ®Google Scholar
• Lorenzo Carrero J, Gonzalez Barcia M, Perez Flores I. Sterile endophthalmitis after benzyl alcohol filtered triamcinolone acetonide injection. Arch Ophthalmol 2008;126(1):142-3
   PubMed Web of Science ®Google Scholar
• Wang LC, Yang CM. Sterile endophthalmitis following intravitreal injection of triamcinolone acetonide. Ocul Immunol Inflamm 2005;13(4):295-300
   PubMed Web of Science ®Google Scholar
• Jonas JB, Kreissig I, Sofker A, Degenring RF. Intravitreal injection of triamcinolone for diffuse diabetic macular edema. Arch Ophthalmol 2003;121(1):57-61
   PubMed Web of Science ®Google Scholar
• Kogure A, Ohkoshi K, Kogure S, Efficacy and retention times of intravitreal triamcinolone acetonide for macular edema. Jpn J Ophthalmol 2008;52(2):122-6
   PubMed Web of Science ®Google Scholar
• Oishi M, Maeda S, Hashida N, Pharmacokinetic behavior of intravitreal triamcinolone acetonide prepared by a hospital pharmacy. Jpn J Ophthalmol 2008;52(6):489-92
   PubMed Web of Science ®Google Scholar
• Shen L, You Y, Sun S, Intraocular and systemic pharmacokinetics of triamcinolone acetonide after a single 40-mg posterior subtenon application. Ophthalmology 2010;117(12):2365-71
   PubMed Web of Science ®Google Scholar
• Cordero Coma M, Sobrin L, Onal S, Intravitreal bevacizumab for treatment of uveitic macular edema. Ophthalmology 2007;114(8):1574-9; e1571
   PubMed Web of Science ®Google Scholar
• Flach AJ. The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery. Trans Am Ophthalmol Soc 1998;96:557-634
   PubMedGoogle Scholar
• Bae JH, Lee CS, Lee SC. Efficacy and safety of intravitreal bevacizumab compared with intravitreal and posterior sub-tenon triamcinolone acetonide for treatment of uveitic cystoid macular edema. Retina 2011;31(1):111-18
   PubMed Web of Science ®Google Scholar
• Shimura M, Nakazawa T, Yasuda K, Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema. Am J Ophthalmol 2008;145(5):854-61
   PubMed Web of Science ®Google Scholar
• Bakri SJ, Snyder MR, Reid JM, Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology 2007;114(5):855-9
   PubMed Web of Science ®Google Scholar
• Krohne TU, Eter N, Holz FG, Meyer CH. Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans. Am J Ophthalmol 2008;146(4):508-12
   PubMed Web of Science ®Google Scholar