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Bibliography
- Lindsay MA. Target discovery. Nat Rev Drug Discov 2003;6:831-8
- van de Waterbeemd H, Gifford E. ADMET in silico modelling: towards prediction paradise? Nat Rev Drug Discov 2003;2:192-204
- Knowles J, Gromo G. A guide to drug discovery: target selection in drug discovery. Nat Rev Drug Discov 2003;2:63-9
- Keiser MJ, Setola V, Irwin JJ, Predicting new molecular targets for known drugs. Nature 2009;462:175-81
- Yang Y, Adelstein SJ, Kassis AI. Target discovery from data mining approaches. Drug Discov Today 2009;14:147-54
- Scheiber J, Chen B, Milik M, Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis. J Chem Inf Model 2009;49:308-17
- Tan Y-T, Tillett DJ, McKay IA. Molecular strategies for overcoming antibiotic resistance in bacteria. Mol Med Today 2000;6:309-14
- Levy J. The effects of antibiotic use on gastrointestinal function. Am J Gastroenterol 2000;95:8-10
- Chandra N. Computational systems approach for drug target discovery. Expert Opin Drug Discov 2009;4:1221-36
- Blundell TL, Sibanda BL, Montalvao RW, Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery. Philos Trans R Soc Lond B Biol Sci 2006;361:413-23
- Al-Lazikani B, Gaulton A, Paolini G, The Molecular basis of predicting. Wiley-VCH Verlag GmbH; Druggability: 2008
- Perot S, Sperandio O, Miteva MA, Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery. Drug Discov Today 2010;15:656-67
- Chandra N, Anand P, Yeturu K. Structural bioinformatics: deriving biological insights from protein structures. Interdiscip Sci 2010;2:347-66
- Gao Z, Li H, Zhang H, PDTD: a web-accessible protein database for drug target identification. BMC Bioinformatics 2008;9:104
- Raman K, Yeturu K. Chandra N. targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis. BMC Syst Biol 2008;2:109
- Xie L, Xie L, Bourne PE. Structure-based systems biology for analyzing off-target binding. Curr Opin Struct Biol 2011;21:189-99
- Voit EO. Computational analysis of biochemical systems. Cambridge University Press; Cambridge, UK; 2000
- Oberhardt MA, Palsson BO, Papin JA. Applications of genome-scale metabolic reconstructions. Mol Syst Biol 2009;5:320
- Zhao S, Li S. Network-based relating pharmacological and genomic spaces for drug target identification. PLoS One 2010;5:e11764
- Hasan S, Daugelat S, Rao PSS, Prioritizing genomic drug targets in pathogens: application to mycobacterium tuberculosis. PLoS Comput Biol 2006;2:e61
- Strong M, Eisenberg D. The protein network as a tool for finding novel drug targets. Prog Drug Res 2007;64:193-215
- Forst CV. Network genomics – A novel approach for the analysis of biological systems in the post-genomic era. Mol Biol Rep 2002;29:265-80
- Raman K, Chandra N. Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance. BMC Microbiol 2008;8:234
- Vaz RJ, Klabunde T. Antitargets: prediction and prevention of drug side effects. Wiley-VCH Verlag GmbH & Co. KGaA; Weinheim, Germany; 2008
- Hopkins AL. Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol 2008;4:682-90
- Raman K, Vashisht R, Chandra N. Strategies for efficient disruption of metabolism in Mycobacterium tuberculosis from network analysis. Mol Biosyst 2009;5:1740-51
- Aguero F, Al-Lazikani B, Aslett M, Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov 2008;7:900-7
- Sams-Dodd F. Target-based drug discovery: is something wrong? Drug Discov Today 2005;10:139-47
- Brown D. Unfinished business: target-based drug discovery. Drug Discov Today 2007;12:1007-12