255
Views
6
CrossRef citations to date
0
Altmetric
Reviews

Understanding and creating value from open source drug discovery for neglected tropical diseases

& (Senior Outsourcing Manager)
Pages 643-657 | Published online: 02 Jun 2012

Bibliography

  • Hunter J, Stephens S. Is open innovation the way forward for big pharma? Nat Rev Drug Discov 2010;9:87-8
  • Munos B. Can open-source drug R&D repower pharmaceutical innovation? Clin Pharmacol Ther 2010;87(5):534-6
  • Wagner J. Open-minded to open innovation and precompetitive collaboration. Clin Pharmacol Ther 2010;87(5):511-15
  • Wagner JA, Prince M, Wright EC, The biomarkers consortium: practice and pitfalls of open-source precompetitive collaboration. Clin Pharmacol Ther 2010;87(5):539-42
  • Weigelt J. The case for open-access chemical biology. EMBO Rep 2009;10(1):941-5
  • Edwards A. Open-source science to enable drug discovery. Drug Discov Today 2008;13(17/18):731-3
  • Hess C, Ostrom E. Understanding knowledge as a commons: from theory to practice. MIT Press; Cambridge: 2006
  • Foray D. The economics of knowledge. MIT Press; Cambridge: 2004
  • Allarakhia M, Kilgour DM, Fuller D. Modeling the incentive to participate in open source biopharmaceutical innovation. R D Manag 2010;40(1):50-66
  • Reichman JH, Dedeurwaerdere T, Uhlir PF. Designing the microbial research commons: global intellectual property strategies for assessing and using essential knowledge assets. 2010; under review
  • Nwaka S, Hudson A. Innovative lead discovery strategies for tropical diseases. Nat Rev Drug Discov 2006;5(11):941-55
  • Renslo AR, McKerrow JH. Drug discovery and development for neglected parasitic diseases. Nat Chem Biol 2006;2(12):701-10
  • Allarakhia M, Strandburg K. A Cultural Commons Study of New Approaches to Drug Development. Case Studies from the Fight Against Malaria, Convening Cultural Commons, Conference of the Engelberg Center on Innovation Law & Policy; 2011
  • Ardal C, Alstadsæter A, Røttingen J-A. Common characteristics of open source software development and applicability for drug discovery: a systematic review. Health Res Policy Syst 2011;9:36
  • Chesbrough HW. The era of open innovation. MIT Sloan Manag Rev 2003;44:35-41
  • Chesbrough HW, Vanhaverbeke W, West J. Open Innovation: researching a new paradigm. Oxford University Press; Oxford: 2006
  • Masum H, Harris R. Open Source for Neglected Diseases: Challenges and Opportunities. Center for Global Health R&D Policy Assessment; 22 February 2011
  • Chan L, Kirsop B, Arunachalam S. Towards open and equitable access to research and knowledge for development. PLoS Med 2011;8(3):e1001016
  • Madison MJ, Frischmann B, Strandburg K. Constructing commons in the cultural environment. Cornell Law Rev 2010;95:657-710
  • Ostrom E, Gardner R, Walker J. Rules, games and common-pool resources. University of Michigan Press; Ann Arbor: 1994
  • Allarakhia M, Walsh S. Managing knowledge assets under conditions of radical change: the case of the pharmaceutical industry. Technovation 2011;31(2-3):105-17
  • Banzi R, Moja L, Pistotti V, Conceptual frameworks and empirical approaches used to assess the impact of health research: an overview of reviews. Health Res Policy Syst 2011;9(1):26
  • Todd MH. Open access and open source in chemistry. Chem Cent J 2007;1:3
  • Aksoy S. Solutions to neglected tropical diseases require vibrant local scientific communities. PLoS Negl Trop Dis 2010;4(3):e662
  • Available from: www.plosntds.org [Last accessed 15 February 2012]
  • Antelman K. Do open access articles have a greater research impact?, college & research libraries news. American Library Association; US 2004. p. 372-82
  • Weiss D. Measuring success of open source projects using web search engines. The First International Conference on Open Source Systems; 24 October 2005
  • Barnes MR, Harland L, Foord SM, Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery. Nat Rev Drug Discov 2009;9:701-8
  • Available from: www.ebi.ac.uk/chemblntd [Last accessed 15 February 2012]
  • Maurer SM, Rai A, Sali A. Finding cures for tropical diseases: is open source an answer? PLoS Med 2004;1(3):e56
  • Orti L, Carbajo RJ, Pieper U, A kernel for open source drug discovery in tropical diseases. PLoS Negl Trop Dis 2009;3(4):e418
  • Everts S. Online research communities aim to unite scientists worldwide to find cures for neglected disease. Chem Eng News 2006;84(30):34-5
  • Woelfle M, Olliaro P, Todd MH. Open science is a research accelerator. Nat Chem 2011;3:745-8
  • Magarinos MP, Carmona SJ, Crowther GJ, TDR targets: a chemogenomics resource for neglected diseases. Nucleic Acids Res 2012;40(D1):D1118-27
  • Available from: tdrtargets.org [Last accessed 22 February 2012]
  • Ridley RG, Fletcher ER. Making a difference: 30 years of TDR. Nat Rev Microbiol 2008;6(5):401-7
  • Crowther GJ, Shanmugam D, Carmona SJ, Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PLoS Negl Trop Dis 2010;4(8):e804
  • Available from: www.malariagen.com [Last accessed August 2011]
  • Bhardwaj A, Scaria V, Raghava GP, Open Source Drug Discovery Consortium, Brahmachari SK. Open source drug discovery: A new paradigm of collaborative research in tuberculosis drug development. Tuberculosis 2011;91(5):479-86
  • Available from: www.osdd.net [Last accessed 15 February 2012]
  • Hurlimann E, Schur N, Boutsika K, Toward an open-access global database for mapping, control, and surveillance of neglected tropical diseases. PLoS Negl Trop Dis 2011;5(12):e1404
  • Available from: www.gntd.org [Last accessed 22 February 2012]
  • New research identifies promising leads to follow in search for medicines to fight malaria. GSK; 19 May 2010
  • Edlin C. The importance of patent sharing in neglected disease drug discovery. Future Med Chem 2011;3(11):1331-4
  • Rai AK, Reichman JH, Uhlir PF, Crossman CR. Pathways across the valley of death: novel intellectual property strategies for accelerated drug discovery. Yale J Health Policy Law Ethics 2008;8(1):53-89
  • Leading Pharmaceutical Companies & Research Institutions Offer IP and Expertise for use in Treating Neglected Tropical Diseases as Part of WIPO Re:Search. WIPO; 26 October 2011
  • WIPO NTD Consortium Access Provisions Set a Bad Precedent by Excluding Countries & Patients. MSF; October 26 2011
  • Drugs for Neglected Diseases Initiative. DNDi Joins WIPO Open Innovation Platform But Calls for More Ambitious Provisions for Innovation and Access. DNDi; 26 October 2011
  • Kapczynski A, Chaifetz S, Benkler Y, Katz Z. Addressing global health inequities: an open licensing approach for University Innovations. Berkeley Technol Law J 2005;20:1031-114
  • Scott WL, O'Donnell MJ. Distributed drug discovery, part 1: linking academia and combinatorial chemistry to find drug leads for developing world diseases. J Comb Chem 2009;11(1):3-13
  • IUPUI Chemists Develop Distributed Drug Discovery: Finding Drugs for Neglected Diseases. IUPUI; June 15 2009
  • Correa P. Scientists use global computer network to find leishmaniasis drugs. SciDev.Net, September 302011
  • Scott C, Nunez M. Grid Computing guiding malaria drug discovery. SciDev.Net, May 112009
  • Stevens R, McEntire R, Goble C, Grid and the drug discovery process. Drug Discovery Today 2004;2(4):140-8
  • Chesler EJ, Baker EJ. The importance of open-source integrative genomics to drug discovery. Curr Opin Drug Discov Devel 2010;13(3):310-16
  • Reichman JH, Uhlir PF. A contractually reconstructed research commons for scientific data: international considerations. In: Essanu JM, Uhlir PF, editors. Open access and the public domain in digital data and information for science: proceedings of an international symposium. National Academics Press; Washington: 2004. p. 98-102
  • Uhlir PF. Designing the microbial commons: proceedings of an international workshop. The National Academies Press; Washington DC: 2011
  • Guth RA. Glaxo tries a linux approach. Wall Street J 2010
  • Joint Policy on Data Sharing, Intellectual Property and Publications. MalariaGen; 15 July 2005
  • , von Lakhani KHippel EV. How open source software works: “Free” user-to-user assistance. Res Policy 2003;32(6):923-43
  • Roy A, McDonald PR, Chaguturu R. Recent trends in collaborative, open source drug discovery. Open Conf Proc J 2011;2:130-136.
  • Hughes B. A Wellcome experiment in seeding drug discovery. Nat Drug Discov 2010;9(3):178-80
  • Butler D. Open-source science takes on neglected disease. Nature February 4, 2010
  • Wilson ME, Ko AI, Reis MG. Collaborative teaching and learning: a model for building capacity and partnerships to address NTDs. PLoS Negl Trop Dis 2011;5(3):e939
  • Available from: www.ntd-africa.net/en/fellowships.html [Last accessed 22 February 2012]
  • Available from: globalhealthtrials.tghn.org [Last accessed 22 February 2012]
  • Lessi M, Asadullah K. Crowd sourcing in drug discovery. Nat Rev Drug Discov 2011;10(4):241-2
  • WHO roadmap inspires unprecedented support to defeat neglected tropical diseases. WHO, Geneva February 032012.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.