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Meeting Report

Cambridge Healthtech Institute’s 7th Annual, Identifying and Validating Metabolic Markers for Drug Development and Clinical Studies

Pages 113-115 | Published online: 09 Jan 2014

References

  • Tweeddale H, Notley-McRobb L, Ferenci T. Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool (“metabolome”) analysis. J. Bacteriol.180, 5109–5116 (1998).
  • Nicholson JK, Lindon JC, Holmes E. ‘Metabonomics’: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica29, 1181–1189 (1999).
  • Trujillo E, Davis C, Milner J. Nutrigenomics, proteomics, metabolomics and the practice of dietetics. J. Am. Diet Assoc.106, 403–413 (2006).
  • Kochhar S, Jacobs DM, Ramadan Z, Berruex F, Fuerholz A, Fay LB. Probing gender-specific metabolism differences in humans by nuclear magnetic resonance-based metabonomics. Anal. Biochem.352, 274–281 (2006).
  • Serkova N, Fuller TF, Klawitter J, Freise CE, Niemann CU. H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Kidney Int.67, 1142–1151 (2005).
  • Wishart DS, Tzur D, Knox C et al. HMDB: the Human Metabolome Database. Nucleic Acids Res.35, D521–D526 (2007).

Websites

  • National Institutes of Health www.nih.gov
  • US FDA: The Critical Path to New Medical Products www.fda.gov/oc/initiatives/criticalpath

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