Prenatal infectious and nutritional factors and risk of adult schizophrenia

References

• Eaton WW. Evidence for universality and uniformity of schizophrenia around the world: assessment and implications. In: Search for the Causes of Schizophrenia (IV). Gattaz WF, Hafner H (Eds). Springer-Verlag, Berlin, Germany 21–33 (1999).
   Google Scholar
• McGuffin P, Owen MJ, Farmer AE. Genetic basis of schizophrenia. Lancet346(8976), 678–682 (1995).
   PubMed Web of Science ®Google Scholar
• Davis JO, Phelps JA, Bracha HS. Prenatal development of monozygotic twins and concordance for schizophrenia. Schizophr. Bull.21(3), 357–366 (1995).
   PubMed Web of Science ®Google Scholar
• Bradbury TN, Miller GA. Season of birth in schizophrenia: a review of evidence, methodology, and etiology. Psychol. Bull.98(3), 569–594 (1985).
   PubMed Web of Science ®Google Scholar
• Mortensen PB, Pedersen CB, Westergaard T et al. Effects of family history and place and season of birth on the risk of schizophrenia. N. Engl. J. Med.340(8), 603–608 (1999).
   PubMed Web of Science ®Google Scholar
• Pedersen CB, Mortensen PB. Evidence of a dose–response relationship between urbanicity during upbringing and schizophrenia risk. Arch. Gen. Psychiatry58 (11), 1039–1046 (2001).
   PubMed Web of Science ®Google Scholar
• Van Os J, Pedersen CB, Mortensen PB. Confirmation of synergy between urbanicity and familial liability in the causation of psychosis. Am. J. Psychiatry161(12), 2312–2314 (2004).
   PubMed Web of Science ®Google Scholar
• Krabbendam L, van Os J. Schizophrenia and urbanicity: a major environmental influence – conditional on genetic risk. Schizophr. Bull.31(4), 795–799 (2005).
   PubMed Web of Science ®Google Scholar
• Cantor-Graae E, Selten JP. Schizophrenia and migration: a meta-analysis and review. Am. J. Psychiatry162(1), 12–24 (2005).
   PubMed Web of Science ®Google Scholar
• Selten JP, Veen N, Feller W et al. Incidence of psychotic disorders in immigrant groups to The Netherlands. Br. J. Psychiatry178, 367–372 (2001).
   PubMed Web of Science ®Google Scholar
• Brown AS. New perspectives on the neurodevelopmental hypothesis of schizophrenia. Psychiatr. Ann.29(3), 128–130 (1999).
   Web of Science ®Google Scholar
• Brown AS, Cohen P, Greenwald S, Susser E. Nonaffective psychosis after prenatal exposure to rubella. Am. J. Psychiatry157(3), 438–443 (2000).
   PubMed Web of Science ®Google Scholar
• Brown AS, Cohen P, Harkavy-Friedman J et al. A.E. Bennett Research Award. Prenatal rubella, premorbid abnormalities, and adult schizophrenia. Biol. Psychiatry49(6), 473–486 (2001).
   PubMed Web of Science ®Google Scholar
• Chess S, Korn S, Fernandez P. Psychiatric Disorders of Children with Congenital Rubella. Brunner/Mazel, NY, USA (1971).
   Google Scholar
• Chess S. Follow-up report on autism in congenital rubella. J. Autism Child Schizophr.7(1), 69–81 (1977).
   PubMedGoogle Scholar
• Nurnberger JI Jr, Blehar MC, Kaufmann CA et al. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch. Gen. Psychiatry51(11), 849–859 (1994).
   PubMed Web of Science ®Google Scholar
• Eaton WW. Epidemiology of schizophrenia. Epidemiol. Rev.7, 105–126 (1985).
   PubMed Web of Science ®Google Scholar
• Kendler KS, MacLean CJ, O’Neill FA et al. Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. Am. J. Psychiatry153(12), 1534–1540 (1996).
   PubMed Web of Science ®Google Scholar
• Brown AS. Serologic studies of prenatal infection and schizophrenia. In: Neuropsychiatric Disorders and Infection. Fatemi SH (Ed.). Martin Dunitz-Taylor & Francis Group, London, UK 43–50 (2005).
   Google Scholar
• Brown AS. Prenatal infection and adult schizophrenia: a review and synthesis. Int. J. Ment. Health29, 22–37 (2001).
   Web of Science ®Google Scholar
• Brown AS, Begg MD, Gravenstein S et al. Serologic evidence for prenatal influenza in the etiology of schizophrenia. Arch. Gen. Psychiatry61, 774–780 (2004).
   PubMed Web of Science ®Google Scholar
• van den Berg BJ. The California Child Health and Development Studies: twenty years of research. World Health Stat. Q.32(4), 269–286 (1979).
   PubMedGoogle Scholar
• van den Berg BJ. The California Child Health and Development Studies. In: Handbook of Longitudinal Research. Mednick SA, Harway M, Finello K (Eds). Praeger, NY, USA 166–179 (1984).
   Google Scholar
• Susser ES, Schaefer CA, Brown AS, Begg MD, Wyatt RJ. The design of the Prenatal Determinants of Schizophrenia Study. Schizophr. Bull.26(2), 257–273 (2000).
   PubMed Web of Science ®Google Scholar
• Remington JS, McLeod R, Thulliez P, Desmonts G. Toxoplasmosis. In: Infectious Diseases of the Fetus & Newborn Infant. Remington JS, Klein JO (Eds). WB Saunders Co., PA, USA 205–346 (2001).
   Google Scholar
• Dukes C, Luft B, Durack D. Toxoplasmosis. In: Infections of the Central Nervous System. Scheld WM, Whitley RJ, Durack DT (Eds). Lippincott-Raven, PA, USA, 785–806 (1997).
   Google Scholar
• Brown AS, Schaefer CA, Quesenberry CP Jr, Liu L, Babulas VP, Susser ES. Maternal exposure to toxoplasmosis and risk of schizophrenia in adult offspring. Am. J. Psychiatry162 (4), 767–773 (2005).
   PubMed Web of Science ®Google Scholar
• Corey L, Whitley RJ, Stone EF, Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet1(8575–8576), 1–4 (1988).
   PubMed Web of Science ®Google Scholar
• Ingall D, Sanchez PJ. Syphilis. In: Infectious Diseases of the Fetus & Newborn Infant. Remington JS, Klein JO (Eds). WB Saunders Co., PA, USA 652 (1995).
   Google Scholar
• Babulas V, Factor-Litvak P, Goetz R, Schaefer CA, Brown AS. Prenatal exposure to maternal genital and reproductive infections and adult schizophrenia. Am. J. Psychiatry163(5), 927–929 (2006).
   PubMed Web of Science ®Google Scholar
• Weizman R, Bessler H. Cytokines: stress and immunity. In: Cytokines: Stress and Immunity. Plotnikoff NP, Faith RE, Murgo AJ, Good RA (Eds). CRC Press, FL, USA 1–15 (1999).
   Google Scholar
• Shimoya K, Matsuzaki N, Taniguchi T, Okada T, Saji F, Murata Y. Interleukin-8 level in maternal serum as a marker for screening of histological chorioamnionitis at term. Int. J. Gynaecol. Obstet.57(2), 153–159 (1997).
   PubMed Web of Science ®Google Scholar
• Gilmore JH, Jarskog LF. Exposure to infection and brain development: cytokines in the pathogenesis of schizophrenia. Schizophr. Res.24(3), 365–367 (1997).
   PubMed Web of Science ®Google Scholar
• Brown AS, Hooton J, Schaefer CA et al. Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring. Am. J. Psychiatry161(5), 889–895 (2004).
   PubMed Web of Science ®Google Scholar
• Harker LA, Ross R, Slichter SJ, Scott CR. Homocystine-induced arteriosclerosis: the role of endothelial cell injury and platelet response in its genesis. J. Clin. Invest.58(3), 731–741 (1976).
   PubMed Web of Science ®Google Scholar
• Nelen WL, Bulten J, Steegers EA, Blom HJ, Hanselaar AG, Eskes TK. Maternal homocysteine and chorionic vascularization in recurrent early pregnancy loss. Hum. Reprod.15(4), 954–960 (2000).
   PubMed Web of Science ®Google Scholar
• Holmes VA. Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis? Proc. Nutr. Soc.62(2), 479–493 (2003).
   PubMed Web of Science ®Google Scholar
• Starkebaum G, Harlan JM. Endothelial-cell injury due to copper-catalyzed hydrogen-peroxide generation from homocysteine. J. Clin. Invest.77(4), 1370–1376 (1986).
   PubMed Web of Science ®Google Scholar
• Parnetti L, Bottiglieri T, Lowenthal D. Role of homocysteine in age-related vascular and non-vascular diseases. Aging. Clin. Exp. Res.9(4), 241–257 (1997).
   Web of Science ®Google Scholar
• di Simone N, Riccardi P, Maggiano N et al. Effect of folic acid on homocysteine-induced trophoblast apoptosis. Mol. Hum. Reprod.10(9), 665–669 (2004).
   PubMedGoogle Scholar
• Murphy MM, Scott JM, Arija V, Molloy AM, Fernandez-Ballart JD. Maternal homocysteine before conception and throughout pregnancy predicts fetal homocysteine and birth weight. Clin. Chem.50(8), 1406–1412 (2004).
   PubMed Web of Science ®Google Scholar
• Baschat AA. Fetal responses to placental insufficiency: an update. BJOG111 (10), 1031–1041 (2004).
   PubMed Web of Science ®Google Scholar
• Lipton SA, Kim WK, Choi YB et al. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc. Natl Acad. Sci. USA94(11), 5923–5928 (1997).
   PubMed Web of Science ®Google Scholar
• Coyle JT, Tsai GC. NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia. Disorders of synaptic plasticity and schizophrenia. Int. Rev. Neurobiol.59, 491–515 (2004).
   Google Scholar
• Javitt DC, Steinschneider M, Schroeder CE, Arezzo JC. Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation: implications for schizophrenia. Proc. Natl Acad. Sci. USA.93(21), 11962–11967 (1996).
   PubMed Web of Science ®Google Scholar
• Brown AS, Bottiglieri T, Schaefer CA et al. Elevated prenatal homocysteine levels as a risk factor for schizophrenia. Arch. Gen. Psychiatry64(1), 31–39 (2007).
   PubMed Web of Science ®Google Scholar
• Whitley RJ, Stagno S. Perinatal infections. In: Infections of the Central Nervous System. Scheld WM, Whitley RJ, Durack DT (Eds). Lippincott-Raven, PA, USA 223–253 (1997).
   Google Scholar
• Boue JG, Boue A. Effects of rubella virus infection on the division of human cells. Am. J. Dis. Child.118(1), 45–48 (1969).
   PubMedGoogle Scholar
• Rorke LB. Nervous system lesions in the congenital rubella syndrome. Arch. Otolaryngol.98(4), 249–251 (1973).
   PubMedGoogle Scholar
• Kemper TL, Lecours AR, Gates MJ, Yakovlev PI. Retardation of the myelo- and cytoarchitectonic maturation of the brain in the congenital rubella syndrome. Res. Publ. Assoc. Res. Nerv. Ment. Dis.51, 23–62 (1973).
   PubMedGoogle Scholar
• Townsend JJ. Rubella virus disease. In: Handbook of Neurovirology. McKendall RR, Stropp WG (Eds). Marcel Dekker, NY, USA 603–611 (1994).
   Google Scholar
• Frenkel JK, Nelson BM, Ariasstella J. Immunosuppression and toxoplasmic encephalitis – clinical and experimental aspects. Hum. Path.6(1), 97–111 (1975).
   PubMed Web of Science ®Google Scholar
• DeLisi LE. Is there a viral or immune dysfunction etiology to schizophrenia? Re-evaluation a decade later. Schizophr. Res.22(1), 1–4 (1996).
   PubMedGoogle Scholar
• Wright P, Takei N, Murray RM, Sham PC. Seasonality, prenatal influenza exposure, and schizophrenia. In: Prenatal Exposures in Schizophrenia. Susser ES, Brown AS, Gorman JM (Eds). American Psychiatric Press, Inc., DC, USA 89–112 (1999).
   Google Scholar
• Atta-ur-Rahman, Harvey K, Siddiqui RA. Interleukin-8: an autocrine inflammatory mediator. Curr. Pharm. Des.5(4), 241–253 (1999).
   PubMedGoogle Scholar
• Mukaida N. The roles of cytokine receptors in diseases. Rinsho Byori48(5), 409–415 (2000).
   PubMedGoogle Scholar
• Detmers PA, Lo SK, Olsen-Egbert E, Walz A, Baggiolini M, Cohn ZA. Neutrophil activating protein 1/interleukin-8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J. Exp. Med.171(4), 1155–1162 (1990).
   PubMed Web of Science ®Google Scholar
• Huber AR, Kunkel SL, Todd RF III, Weiss SJ. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science254(5028), 99–102 (1991).
   PubMed Web of Science ®Google Scholar
• Brown AS, Susser E. Plausibility of prenatal rubella, influenza, and other viral infections as risk factors for schizophrenia. In: Prenatal Exposures in Schizophrenia. Susser ES, Brown AS, Gorman JM (Eds). American Psychiatric Press, Inc., DC, USA 113–131 (1999).
   Google Scholar
• Koenig JI, Kirkpatrick B, Lee P. Glucocorticoid hormones and early brain development in schizophrenia. Neuropsychopharmacology27(2), 309–318 (2002).
   PubMed Web of Science ®Google Scholar
• Brown AS, Susser ES, Butler PD, Richardson AR, Kaufmann CA, Gorman JM. Neurobiological plausibility of prenatal nutritional deprivation as a risk factor for schizophrenia. J. Nerv. Ment. Dis.184(2), 71–85 (1996).
   PubMed Web of Science ®Google Scholar
• Graham I. Homocysteine Metabolism: From Basic Science to Clinical Medicine. Kluwer Academic Publishers, MA, USA (1997).
   Google Scholar
• Lewis CA, Pancharuniti N, Sauberlich HE. Plasma folate adequacy as determined by homocysteine level. Ann. NY Acad. Sci.669, 360–362 (1992).
   PubMed Web of Science ®Google Scholar
• Goff DC, Coyle JT. The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am. J. Psychiatry158(9), 1367–1377 (2001).
   PubMed Web of Science ®Google Scholar
• McGrath J. Hypothesis: is low prenatal vitamin D a risk-modifying factor for schizophrenia? Schizophr. Res.40(3), 173–177 (1999).
   PubMed Web of Science ®Google Scholar
• McGrath J, Eyles D, Mowry B et al. Low maternal vitamin D as a risk factor for schizophrenia: a pilot study using banked sera. Schizophr. Res.63(1–2), 73–78 (2003).
   PubMed Web of Science ®Google Scholar
• MacKay-Sim A, Feron F, Eyles D, Burne T, McGrath J. Schizophrenia, vitamin D, and brain development. Int. Rev. Neurobiol.59, 351–380 (2004).
   PubMed Web of Science ®Google Scholar
• Anton ES, Marchionni MA, Lee KF, Rakic P. Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development124(18), 3501–3510 (1997).
   PubMed Web of Science ®Google Scholar
• Kamiya A, Kubo K, Tomoda T et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat. Cell Biol.7(12), 1167–1178 (2005).
   PubMed Web of Science ®Google Scholar
• Lencz T, Morgan TV, Athanasiou M et al. Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. Mol. Psychiatry12(6), 572–580 (2007).
   PubMed Web of Science ®Google Scholar
• Tan EC, Chong SA, Lim LC et al. Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders. Psychiatr. Genet.14(4), 227–231 (2004).
   PubMedGoogle Scholar
• Virgos C, Martorell L, Simo JM et al. Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant: lack of association with schizophrenia. Neuroreport10(10), 2035–2038 (1999).
   PubMed Web of Science ®Google Scholar
• Shi L, Fatemi SH, Sidwell RW, Patterson PH. Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J. Neurosci.23(1), 297–302 (2003).
   PubMed Web of Science ®Google Scholar
• Fatemi SH, Emamian ES, Kist D et al. Defective corticogenesis and reduction in reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice. Mol. Psychiatry4(2), 145–154 (1999).
   PubMed Web of Science ®Google Scholar
• Zuckerman L, Rehavi M, Nachman R, Weiner I. Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia. Neuropsychopharmacology28(10), 1778–1789 (2003).
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. CDC Recommendations Regarding Selected Conditions Affecting Women’s Health, 49 No. RR-2. Centers for Disease Control and Prevention, GA, USA 57–75 (2000).
   Google Scholar
• Amminger GP, Berger GE, Schafer MF et al. Omega-3 fatty acids supplementation in children withautism: a double-blind randomized, placebo-controlled pilot study. Biol. Psychiatry61(4), 551–553 (2007).
   PubMed Web of Science ®Google Scholar
• Brown AS, Schaefer CA, Wyatt RJ et al. Maternal exposure to respiratory infections and adult schizophrenia spectrum disorders: a prospective birth cohort study. Schizophr. Bull.26(2), 287–295 (2000).
   PubMed Web of Science ®Google Scholar
• Mortensen PB, Norgaard-Pedersen B, Waltoft BL et al.Toxoplasma gondii as a risk factor for early-onset schizophrenia: analysis of filter paper blood samples obtained at birth. Biol. Psychiatry61(5), 688–693 (2007).
   PubMed Web of Science ®Google Scholar
• Buka SL, Tsuang MT, Torrey EF, Klebanoff MA, Bernstein D, Yolken RH. Maternal infections and subsequent psychosis among offspring. Arch. Gen. Psychiatry58(11), 1032–1037 (2001).
   PubMed Web of Science ®Google Scholar
• Susser E, Neugebauer R, Hoek HW et al. Schizophrenia after prenatal famine. Further evidence. Arch. Gen. Psychiatry53(1), 25–31 (1996).
   PubMed Web of Science ®Google Scholar
• St Clair D, Xu M, Wang P et al. Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959–1961. JAMA294(5), 557–562 (2005).
   PubMed Web of Science ®Google Scholar
• Schaefer CA, Brown AS, Wyatt RJ et al. Maternal prepregnant body mass and risk of schizophrenia in adult offspring. Schizophr. Bull.26(2), 275–286 (2000).
   PubMed Web of Science ®Google Scholar