569
Views
16
CrossRef citations to date
0
Altmetric
Review

Human rotavirus vaccine (Rotarix): focus on effectiveness and impact 6 years after first introduction in Africa

, &

References

  • Parashar UD, Hummelman EG, Bresee JS, et al. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 2003;9(5):565-72
  • Gray J, Vesikari T, Van Damme P, et al. Rotavirus. J Pediatric Gastroenterol Nutr 2008;46(Suppl 2):S24-31
  • D’Agostino J. Considerations in assessing the clinical course and severity of rotavirus gastroenteritis. Clin Pediatr 2006;45(3):203-12
  • Soriano-Gabarro M, Mrukowicz J, Vesikari T, Verstraeten T. Burden of rotavirus disease in European Union countries. Pediatr Infect Dis J 2006;25(1 Suppl):S7-S11
  • Cortes JE, Curns AT, Tate JE, Parashar UD. Trends in healthcare utilization for diarrhea and rotavirus disease in privately insured US children <5 years of age, 2001-2006. Pediatr Infect Dis J 2009;28(10):874-8
  • Tate JE, Burton AH, Boschi-Pinto C, et al. 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect Dis 2012;12(2):136-41
  • Mrukowicz J, Szajewska H, Vesikari T. Options for the prevention of rotavirus disease other than vaccination. J Pediatr Gastroenterol Nutr 2008;46(Suppl 2):S32-7
  • World Health Organization. Rotavirus vaccines. WHO position paper - January 2013. Wkly Epidemiol Rec 2013;88(5):49-64
  • O’Ryan M, Vidal R, del Canto F, et al. Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part I: overview, vaccines for enteric viruses and Vibrio cholerae. Hum Vaccin Immunother 2015;11(3):584-600
  • PATH. Country introductions of rotavirus vaccines 2014. Available from: http://sites.path.org/rotavirusvaccine/country-introduction-maps-and-spreadsheet/
  • Yen C, Tate JE, Hyde TB, et al. Rotavirus vaccines: Current status and future considerations. Hum Vaccin Immunother 2014;10(6):1436-48
  • Muhsen K, Shulman L, Kasem E, et al. Effectiveness of rotavirus vaccines for prevention of rotavirus gastroenteritis-associated hospitalizations in Israel: a case-control study. Hum Vaccin 2010;6(6):450-4
  • Braeckman T, Van Herck K, Meyer N, et al. Effectiveness of rotavirus vaccination in prevention of hospital admissions for rotavirus gastroenteritis among young children in Belgium: case-control study. BMJ 2012;345:e4752
  • Castilla J, Beristain X, Martinez-Artola V, et al. Effectiveness of rotavirus vaccines in preventing cases and hospitalizations due to rotavirus gastroenteritis in Navarre, Spain. Vaccine 2012;30(3):539-43
  • Justino MC, Linhares AC, Lanzieri TM, et al. Effectiveness of the monovalent G1P[8] human rotavirus vaccine against hospitalization for severe G2P[4] rotavirus gastroenteritis in Belem, Brazil. Pediatr Infect Dis J 2011;30(5):396-401
  • de Palma O, Cruz L, Ramos H, et al. Effectiveness of rotavirus vaccination against childhood diarrhoea in El Salvador: case-control study. BMJ 2010;340:c2825
  • Patel MM, Patzi M, Pastor D, et al. Effectiveness of monovalent rotavirus vaccine in Bolivia: case-control study. BMJ 2013;346:f3726
  • Yen C, Armero Guardado JA, Alberto P, et al. Decline in rotavirus hospitalizations and health care visits for childhood diarrhea following rotavirus vaccination in El Salvador. Pediatr Infect Dis J 2011;30(1 Suppl):S6-S10
  • Hanquet G, Ducoffre G, Vergison A, et al. Impact of rotavirus vaccination on laboratory confirmed cases in Belgium. Vaccine 2011;29(29-30):4698-703
  • Standaert B, Gomez JA, Raes M, et al. Impact of rotavirus vaccination on hospitalisations in Belgium: comparing model predictions with observed data. PLoS One 2013;8(1):e53864
  • Paulke-Korinek M, Kollaritsch H, Aberle SW, et al. Sustained low hospitalization rates after four years of rotavirus mass vaccination in Austria. Vaccine 2013;31(24):2686-91
  • Macartney KK, Porwal M, Dalton D, et al. Decline in rotavirus hospitalisations following introduction of Australia’s national rotavirus immunisation programme. J Paediatr Child Health 2011;47(5):266-70
  • Safadi MA, Berezin EN, Munford V, et al. Hospital-based surveillance to evaluate the impact of rotavirus vaccination in Sao Paulo, Brazil. Pediatr Infect Dis J 2010;29(11):1019-22
  • Paulke-Korinek M, Kundi M, Rendi-Wagner P, et al. Herd immunity after two years of the universal mass vaccination program against rotavirus gastroenteritis in Austria. Vaccine 2011;29(15):2791-6
  • Gurgel RQ, Alvarez Ade J, Rodrigues A, et al. Incidence of rotavirus and circulating genotypes in Northeast Brazil during 7 years of national rotavirus vaccination. PLoS One 2014;9(10):e110217
  • Richardson V, Hernandez-Pichardo J, Quintanar-Solares M, et al. Effect of rotavirus vaccination on death from childhood diarrhea in Mexico. N Engl J Med 2010;362(4):299-305
  • Gastanaduy PA, Sanchez-Uribe E, Esparza-Aguilar M, et al. Effect of rotavirus vaccine on diarrhea mortality in different socioeconomic regions of Mexico. Pediatrics 2013;131(4):e1115-20
  • Lanzieri TM, Linhares AC, Costa I, et al. Impact of rotavirus vaccination on childhood deaths from diarrhea in Brazil. Int J Infect Dis 2011;15(3):e206-10
  • do Carmo GM, Yen C, Cortes J, et al. Decline in diarrhea mortality and admissions after routine childhood rotavirus immunization in Brazil: a time-series analysis. PLoS Med 2011;8(4):e1001024
  • Bayard V, DeAntonio R, Contreras R, et al. Impact of rotavirus vaccination on childhood gastroenteritis-related mortality and hospital discharges in Panama. Int J Infect Dis 2012;16(2):e94-8
  • GAVI rotavirus vaccine support timeline 2014. Available from: http://www.gavi.org/support/nvs/rotavirus/
  • World Health Organization. Reported estimates of rotavirus vaccine last dose coverage. 2014. Available from: http://apps.who.int/immunization_monitoring/globalsummary/timeseries/tscoveragerota_last.html
  • World Bank. World bank data - country and lending groups. 2003. Available from: http://data.worldbank.org/about/country-classifications/country-and-lending-groups
  • World Health Organization. World health report: List of member states by WHO region and mortality stratum. 2003
  • Msimang VM, Page N, Groome MJ, et al. Impact of rotavirus vaccine on childhood diarrheal hospitalization following introduction into the South African public immunization program. Pediatr Infect Dis J 2013;32(12):1359-64
  • World Bank. World bank GNI per capita in PPP. 2013. Available from: http://data.worldbank.org/indicator/NY.GNP.PCAP.PP.CD
  • Statistics South Africa. Statistics: living condition: poverty 2014. Available from: http://beta2.statssa.gov.za/?page_id=739&id=1
  • Pali Lehohla S-G. Poverty trends in south africa - An examination of absolute poverty between 2006 and 2011. Statistics South Africa, Pretoria, South Africa, 2014, 80
  • Groome MJ, Page N, Cortese MM, et al. Effectiveness of monovalent human rotavirus vaccine against admission to hospital for acute rotavirus diarrhoea in South African children: a case-control study. Lancet Infect Dis 2014;14(11):1096-104
  • Madhi SA, Cunliffe NA, Steele D, et al. Effect of human rotavirus vaccine on severe diarrhea in African infants. N Engl J Med 2010;362(4):289-98
  • Madhi SA, Kirsten M, Louw C, et al. Efficacy and immunogenicity of two or three dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons: a randomized, double-blind, placebo-controlled trial. Vaccine 2012;30(Suppl 1):A44-51
  • Cunliffe N, Zaman K, Rodrigo C, et al. Early exposure of infants to natural rotavirus infection: a review of studies with human rotavirus vaccine RIX4414. BMC Pediatr 2014;14(1):295
  • Sanderson C, Clark A, Taylor D, Bolanos B. Global review of rotavirus morbidity and mortality data by age and region. 2011
  • Buttery JP, Lambert SB, Grimwood K, et al. Reduction in rotavirus-associated acute gastroenteritis following introduction of rotavirus vaccine into Australia’s National Childhood vaccine schedule. Pediatr Infect Dis J 2011;30(1 Suppl):S25-9
  • Barron P, Pillay Y, Doherty T, et al. Eliminating mother-to-child HIV transmission in South Africa. Bull World Health Organ 2013;91(1):70-4
  • Slogrove A, Reikie B, Naidoo S, et al. HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life. J Trop Pediatr 2012;58(6):505-8
  • World Health Organization. Global health observatory data repository - HIV/AIDS prevalence in sub-Saharan Africa, data by sex and residence 2014. Available from: http://apps.who.int/gho/data/node.main.247?lang=en
  • Enweronu-Laryea CC, Boamah I, Sifah E, et al. Decline in severe diarrhea hospitalizations after the introduction of rotavirus vaccination in Ghana: a prevalence study. BMC Infect Dis 2014;14:431
  • Ghana Ministry of Health. Introduction of new vaccines 2015. Available from: http://www.moh-ghana.org/otherpages.aspx?id=3
  • Bar-Zeev N, Kapanda L, Tate JE, et al. Effectiveness of a monovalent rotavirus vaccine in infants in Malawi after programmatic roll-out: an observational and case-control study. Lancet Infect Dis 2015;15(4):422-8
  • Cunliffe NA, Witte D, Ngwira BM, et al. Efficacy of human rotavirus vaccine against severe gastroenteritis in Malawian children in the first two years of life: a randomized, double-blind, placebo controlled trial. Vaccine 2012;30(Suppl 1)):A36-43
  • Patel M, Shane AL, Parashar UD, et al. Oral rotavirus vaccines: how well will they work where they are needed most? J Infect Dis 2009;200(Suppl 1):S39-48
  • GlaxoSmithKline. Rotarix™ summary of product characteristics. 2014, Last updated 18 April 2014
  • Leshem E, Lopman B, Glass R, et al. Distribution of rotavirus strains and strain-specific effectiveness of the rotavirus vaccine after its introduction: a systematic review and meta-analysis. Lancet Infect Dis 2014;14(9):847-56
  • Velasquez D, Parashar U, Jiang B. Strain diversity plays no major role in the varying efficacy of rotavirus vaccines: An overview. Infection, Genetics and Evolution 2014;28:561-71
  • Murphy TV, Gargiullo PM, Massoudi MS, et al. Intussusception among infants given an oral rotavirus vaccine. N Engl J Med 2001;344(8):564-72
  • Patel MM, Haber P, Baggs J, et al. Intussusception and rotavirus vaccination: a review of the available evidence. Expert Rev Vaccines 2009;8(11):1555-64
  • Jiang J, Jiang B, Parashar U, et al. Childhood intussusception: a literature review. PLoS One 2013;8(7):e68482
  • European medicines agency. European public assessment report - Annex I Summary of product characteristics. 2009; [Last updated 14 May 2014]
  • Rosillon D, Buyse H, Friedland L, et al. Risk of intussusception after rotavirus vaccination: meta-analysis of postlicensure studies. Pediatr Infect Dis J 2015. [Epub ahead of print]
  • Buttery JP, Danchin MH, Lee KJ, et al. Intussusception following rotavirus vaccine administration: Post-marketing surveillance in the National Immunization Program in Australia. Vaccine 2011;29(16):3061-6
  • Patel M, Steele AD, Parashar UD. Influence of oral polio vaccines on performance of the monovalent and pentavalent rotavirus vaccines. Vaccine 2012;30(Suppl 1):A30-5
  • Valdez Y, Brown EM, Finlay BB. Influence of the microbiota on vaccine effectiveness. Trends Immunol 2014;35(11):526-37
  • Moon SS, Wang Y, Shane AL, et al. Inhibitory effect of breast milk on infectivity of live oral rotavirus vaccines. Pediatr Infect Dis J 2010;29(10):919-23
  • Pott J, Stockinger S, Torow N, et al. Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility. PLoS Pathogens 2012;8(5
  • Imbert-Marcille BM, Barbé L, Dupé M, et al. A FUT2 gene common polymorphism determines resistance to rotavirus A of the P[8] genotype. J Infect Dis 2014;209(8):1227-30
  • Cunliffe NA, Ngwira BM, Dove W, et al. Epidemiology of rotavirus infection in children in Blantyre, Malawi, 1997-2007. J Infect Dis 2010;202(Suppl):S168-74
  • Linhares AC, Gabbay YB, Mascarenhas JD, et al. Immunogenicity, safety and efficacy of tetravalent rhesus-human, reassortant rotavirus vaccine in Belem, Brazil. Bull World Health Organ 1996;74(5):491-500
  • Steele AD, De Vos B, Tumbo J, et al. Co-administration study in South African infants of a live-attenuated oral human rotavirus vaccine (RIX4414) and poliovirus vaccines. Vaccine 2010;28(39):6542-8
  • Tregnaghi MW, Abate HJ, Valencia A, et al. Human rotavirus vaccine is highly efficacious when coadministered with routine expanded program of immunization vaccines including oral poliovirus vaccine in Latin America. Pediatr Infect Dis J 2011;30(6):e103-8
  • Ruiz-Palacios GM, Perez-Schael I, Velazquez FR, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med 2006;354(1):11-22
  • Trang NV, Braeckman T, Lernout T, et al. Prevalence of rotavirus antibodies in breast milk and inhibitory effects to rotavirus vaccines. Hum Vaccin Immunother 2014;10(12):3681-7
  • Groome MJ, Moon SS, Velasquez D, et al. Effect of breastfeeding on immunogenicity of oral live-attenuated human rotavirus vaccine: a randomized trial in HIV-uninfected infants in Soweto, South Africa. Bull World Health Organ 2014;92(4):238-45
  • Van Damme P, Giaquinto C, Huet F, et al. Multicenter prospective study of the burden of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL study. J Infect Dis 2007;195(Suppl 1):S4-S16
  • Velazquez FR, Matson DO, Calva JJ, et al. Rotavirus infections in infants as protection against subsequent infections. N Engl J Med 1996;335(14):1022-8
  • Gladstone BP, Ramani S, Mukhopadhya I, et al. Protective effect of natural rotavirus infection in an Indian birth cohort. N Engl J Med 2011;365(4):337-46
  • O’Ryan ML, Clemens R. Rotavirus vaccines roll-out in resource-deprived regions. Lancet Infect Dis 2015
  • Steele AD, Neuzil KM, Cunliffe NA, et al. Human rotavirus vaccine Rotarix provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial. BMC Infect Dis 2012;12:213
  • Mwenda JM, Tate JE, Parashar UD, et al. African rotavirus surveillance network: a brief overview. Pediatr Infect Dis J 2014;33(Suppl 1):S6-8
  • Mwenda JM, Tate JE, Steele AD, Parashar UD. Preparing for the scale-up of rotavirus vaccine introduction in Africa: establishing surveillance platforms to monitor disease burden and vaccine impact. Pediatr Infect Dis J 2014;33(Suppl 1):S1-5
  • O’Ryan M. The ever-changing landscape of rotavirus serotypes. Pediatr Infect Dis J 2009;28:S60-2

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.