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Editorials

Toll like receptors: a new hope on the horizon to treat multiple sclerosis

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References

  • DeLuca J, Nocentini U. Neuropsychological, medical and rehabilitative management of persons with multiple sclerosis. NeuroRehabilitation 2011;29(3):197-219
  • Dutta R, Trapp BD. Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog Neurobiol 2011;93(1):1-12
  • Trapp BD, Nave KA. Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci 2008;31:247-69
  • Castro-Borrero W, Graves D, Frohman TC, et al. Current and emerging therapies in multiple sclerosis: a systematic review. Ther Adv Neurol Disord Therapeutic advances in neurological disorders 2012;5(4):205-20
  • Steinman L. Immunology of relapse and remission in multiple sclerosis. Annu Rev Immunol 2014;32:257-81
  • Rezaei N. Therapeutic targeting of pattern-recognition receptors. Int Immunopharmacol 2006;6(6):863-9
  • Akira S. Pathogen recognition by innate immunity and its signaling. Proc Jpn Acad Ser B Phys Biol Sci 2009;85(4):143-56
  • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4(7):499-511
  • Hedayat M, Takeda K, Rezaei N. Prophylactic and therapeutic implications of toll like receptor ligands. Med Res Rev 2012;32(2):294-325
  • Zuany-Amorim C, Hastewell J, Walker C. Toll-like receptors as potential therapeutic targets for multiple diseases. Nat Rev Drug Discov 2002;1(10):797-807
  • Gooshe M, Abdolghaffari AH, Gambuzza ME, Rezaei N. The role of Toll-like receptors in multiple sclerosis and possible targeting for therapeutic purposes. Rev Neurosci 2014. [Epub ahead of print]
  • Jasani B, Navabi H, Adams M. Ampligen: a potential toll-like 3 receptor adjuvant for immunotherapy of cancer. Vaccine 2009;27(25-26):3401-4
  • Touil T, Fitzgerald D, Zhang GX, et al. Cutting Edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-beta. J Immunol 2006:177(11):7505-9
  • Henrick BM, Nag K, Yao XD, et al. Milk matters: soluble toll-like receptor 2 (sTLR2) in breast milk significantly inhibits HIV-1 infection and inflammation. PLoS One 2012;7(7):e40138
  • Hayashi T, Gray CS, Chan M, et al. Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. Proc Natl Acad Sci USA 2009;106(8):2764-9
  • Toshchakov VY, Vogel SN. Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions. Expert Opin Biol Ther 2007;7(7):1035-50
  • Antosz H, Choroszynska D. [Negative regulation of toll-like receptor signalling]. Postepy higieny i medycyny doswiadczalnej (Online) 2013;67:339-50
  • Filippini G, Del Giovane C, Vacchi L, et al. Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis. Cochrane Database Syst Rev 2013;6: Cd008933
  • Ciccone A, Beretta S, Brusaferri F, et al. Corticosteroids for the long-term treatment in multiple sclerosis. Cochrane Database Syst Rev 2008(1): Cd006264

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