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Reviews

The impact of vitamin D on asthmatic human airway smooth muscle

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Pages 127-135 | Received 16 Oct 2015, Accepted 02 Dec 2015, Published online: 28 Dec 2015

References

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•• In-depth review outlining the association between vitamin D and respiratory diseases as well as current knowledge on vitamin D supplementation as a potential therapeutic option.

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• Clinical trial with relatively large sample size which demonstrated that vitamin D supplementation was ineffective in reducing exacerbations in patients with persistent asthma.

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• Recently concluded clinical trial which showed that vitamin D supplementation was able to improve FEV1 in patients with mild-to-moderate asthma.

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• One of the first studies to demonstrate the effects of vitamin D on expression of genes involved in human ASM cell growth, survival and function.

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• Study highlighting a potential role of vitamin D in the treatment of steroid-resistant asthma.

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